Disruption of glucose homeostasis and induction of insulin resistance by elevated free fatty acids in human L02 hepatocytes

Journal of Endocrinological Investigation

Volumn 32, Issue 5, 2009, Pages 454-459

  Wan, X D ^a,b   Yang, W B ^b   Xia, Y Z ^a   Wang, J F ^a   Lu, T ^a   Wang, X M ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b HENAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Insulin receptor substrate 2; Insulin resistance; L02 hepatocytes; Palmitic acid; Phosphoenolpyruvate carboxykinase

Indexed keywords

FATTY ACID; GLUCOSE; GLYCOGEN; INSULIN; INSULIN RECEPTOR SUBSTRATE 2; PALMITIC ACID; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PROTEIN KINASE B; WORTMANNIN;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME INHIBITION; FATTY ACID BLOOD LEVEL; GLUCOSE HOMEOSTASIS; HUMAN; HUMAN CELL; INSULIN METABOLISM; INSULIN RESISTANCE; LIVER CELL; MEMBRANE DAMAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ACIDS, NONESTERIFIED; GLUCOSE; GLYCOGEN; HEPATOCYTES; HOMEOSTASIS; HUMANS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; ONCOGENE PROTEIN V-AKT; PALMITIC ACID; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; TIME FACTORS; UP-REGULATION;

EID: 70350348685     PISSN: 03914097     EISSN: None     Source Type: Journal    
DOI: 10.3275/6235     Document Type: Article

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