In vitro performance of an injectable hydrogel/microsphere based immunocyte delivery system for localised anti-tumour activity

Biomaterials

Volumn 30, Issue 36, 2009, Pages 6986-6995

  Wang, Chunming ^a   Adrianus, Gerard N ^a   Sheng, Nan ^a   Toh, Shikai ^a   Gong, Yihong ^a   Wang, Dong An ^a  

^a Nanyang Technological University   (Singapore)

Author keywords

Apoptosis; Cancer immunotherapy; Cytokine; Hydrogel; Macrophage; Microsphere

Indexed keywords

APOPTOSIS; CANCER IMMUNOTHERAPY; CARCINOMA CELLS; CELL LEAKAGE; CELL TARGETING; CELL-BASED; CURRENT PRACTICES; CYTOKINE; DELIVERY SYSTEMS; ENGINEERING SOLUTIONS; HIGH SAFETY; IN-VITRO; INJECTABILITY; LOCALISATION; PHYSICAL IMMOBILISATION; TARGETED DELIVERY;

BIOLOGICAL MATERIALS; CELL DEATH; CELL MEMBRANES; MACROPHAGES; MICROSPHERES; THREE DIMENSIONAL; TUMORS;

HYDROGELS;

MICROSPHERE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER IMMUNOTHERAPY; CELL ENCAPSULATION; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; GENE MUTATION; HUMAN; HUMAN CELL; HYDROGEL; IN VITRO STUDY; MACROPHAGE; PRIORITY JOURNAL;

ANIMALS; BIOCOMPATIBLE MATERIALS; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; HUMANS; HYDROGELS; IMMUNOTHERAPY; INJECTIONS; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MATERIALS TESTING; MICROSPHERES; NEOPLASMS;

EID: 70350339788     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.09.006     Document Type: Article

References (32)

1. Caspi R.R. Immunotherapy of autoimmunity and cancer: the penalty for success. Nat Rev Immunol 8 (2008) 970-976
2. Stoeckle C., and Gleske A.K. Immunotherapy: from basic research to clinical applications. Cancer Immunol Immunother 58 (2009) 1129-1136
3. Blattman J.N., and Greenberg P.D. Cancer immunotherapy: a treatment for the masses. Science 305 (2004) 200-205
4. Leen A.M., Rooney C.M., and Foster A.E. Improving T cell therapy for cancer. Annu Rev Immunol 25 (2007) 243-265
5. Coukos G., and Conejo-Garcia J.-R. The tumor microenvironment. In: Disis M.L. (Ed). Immunotherapy of cancer (2006), Humana Press 285-301
6. Carter P. Improving the efficacy of antibody-based cancer therapies. Nat Rev Cancer 1 (2001) 118-129
7. Mackensen A., Meidenbauer N., Vogl S., Laumer M., Berger J., and Andreesen R. Phase I study of adoptive T-cell therapy using antigen-specific CD8+ T cells for the treatment of patients with metastatic melanoma. J Clin Oncol 24 (2006) 5060-5069
8. Sentman C.L., Barber M.A., Barber A., and Zhang T. NK cell receptors as tools in cancer immunotherapy. Adv Cancer Res 95 (2006) 249-292
9. Dranoff G., Jaffee E., Lazenby A., Golumbek P., Levitsky H., Brose K., et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci U S A 90 (1993) 3539-3543
10. Karanikas V., Lurquin C., Colau D., van Baren N., de Smet C., Lethe B., et al. Monoclonal anti-MAGE-3 CTL responses in melanoma patients displaying tumor regression after vaccination with a recombinant canarypox virus. J Immunol 171 (2003) 4898-4904
11. Silk A.W., and Finn O.J. Cancer vaccines: a promising cancer therapy against all odds. Future Oncol 3 (2007) 299-306
12. Williams D.F. On the mechanisms of biocompatibility. Biomaterials 29 (2008) 2941-2953
13. Panza J.L., Wagner W.R., Rilo H.L., Rao R.H., Beckman E.J., and Russell A.J. Treatment of rat pancreatic islets with reactive PEG. Biomaterials 21 (2000) 1155-1164
14. Okamoto N., Chihara R., Shimizu C., Nishimoto S., and Watanabe T. Artificial lymph nodes induce potent secondary immune responses in naive and immunodeficient mice. J Clin Invest 117 (2007) 997-1007
15. Suematsu S., and Watanabe T. Generation of a synthetic lymphoid tissue-like organoid in mice. Nat Biotechnol 22 (2004) 1539-1545
16. Hori Y., Winans A.M., Huang C.C., Horrigan E.M., and Irvine D.J. Injectable dendritic cell-carrying alginate gels for immunization and immunotherapy. Biomaterials 29 (2008) 3671-3682
17. Hori Y., Winans A.M., and Irvine D.J. Modular injectable matrices based on alginate solution/microsphere mixtures that gel in situ and co-deliver immunomodulatory factors. Acta Biomater 5 (2009) 969-982
18. Gong Y., Wang C., Lai R.C., Su K., Zhang F., and Wang D.-A. An improved injectable polysaccharide hydrogel: modified gellan gum for long-term cartilage regeneration in vitro. J Mater Chem 19 (2009) 1968-1977
19. Yu L., and Ding J. Injectable hydrogels as unique biomedical materials. Chem Soc Rev 37 (2008) 1473-1481
20. van Horssen R., Ten Hagen T.L., and Eggermont A.M. TNF-alpha in cancer treatment: molecular insights, antitumor effects, and clinical utility. Oncologist 11 (2006) 397-408
21. Wang C., Gong Y., Zhong Y., Yao Y., Su K., and Wang D.A. The control of anchorage-dependent cell behavior within a hydrogel/microcarrier system in an osteogenic model. Biomaterials 30 (2009) 2259-2269
22. Wang C., Hao J., Zhang F., Su K., and Wang D.A. RNA extraction from polysaccharide-based cell-laden hydrogel scaffolds. Anal Biochem 380 (2008) 333-334
23. Carswell E.A., Old L.J., Kassel R.L., Green S., Fiore N., and Williamson B. An endotoxin-induced serum factor that causes necrosis of tumors. Proc Natl Acad Sci U S A 72 (1975) 3666-3670
24. Dranoff G. Cytokines in cancer pathogenesis and cancer therapy. Nat Rev Cancer 4 (2004) 11-22
25. Yoshida J., Mizuno M., and Wakabayashi T. Interferon-beta gene therapy for cancer: basic research to clinical application. Cancer Sci 95 (2004) 858-865
26. Jakubowski A.A., Bajorin D.F., Templeton M.A., Chapman P.B., Cody B.V., Thaler H., et al. Phase I study of continuous-infusion recombinant macrophage colony-stimulating factor in patients with metastatic melanoma. Clin Cancer Res 2 (1996) 295-302
27. Asadullah K., Sterry W., and Volk H.D. Interleukin-10 therapy-review of a new approach. Pharmacol Rev 55 (2003) 241-269
28. Urban J.L., Shepard H.M., Rothstein J.L., Sugarman B.J., and Schreiber H. Tumor necrosis factor: a potent effector molecule for tumor cell killing by activated macrophages. Proc Natl Acad Sci U S A 83 (1986) 5233-5237
29. Virca G.D., Kim S.Y., Glaser K.B., and Ulevitch R.J. Lipopolysaccharide induces hyporesponsiveness to its own action in RAW 264.7 cells. J Biol Chem 264 (1989) 21951-21956
30. Ruoslahti E., and Reed J.C. Anchorage dependence, integrins, and apoptosis. Cell 77 (1994) 477-478
31. Wang C., Bai J., Gong Y., Zhang F., Shen J., and Wang D.A. Enhancing cell affinity of nonadhesive hydrogel substrate: the role of silica hybridization. Biotechnol Prog 24 (2008) 1142-1146
32. Grigoriou V., Shapiro I.M., Cavalcanti-Adam E.A., Composto R.J., Ducheyne P., and Adams C.S. Apoptosis and survival of osteoblast-like cells are regulated by surface attachment. J Biol Chem 280 (2005) 1733-1739