Effects of Puerariae radix extract on the increasing intestinal permeability in rat with alcohol-induced liver injury

Journal of Ethnopharmacology

Volumn 126, Issue 2, 2009, Pages 207-214

  Zhang, Rongrong ^a   Hu, Yiyang ^a   Yuan, Jianye ^a,b   Wu, Dazheng ^a,b  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b Shanghai Key Laboratory of Complex Prescription   (China)

Author keywords

Alcohol; Intestinal permeability; Liver damage; Puerariae radix; ZO 1

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ASPARTATE AMINOTRANSFERASE; DAIDZEIN; DAIDZIN; PUERARIA EXTRACT; PUERARIN; SUPEROXIDE DISMUTASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL LIVER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DRUG DETERMINATION; ENZYME ANALYSIS; ENZYME INHIBITION; FATTY LIVER; HEPATITIS; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INTESTINE INJURY; INTESTINE MUCOSA PERMEABILITY; LIVER INJURY; LIVER NECROSIS; LIVER PROTECTION; LONG TERM EXPOSURE; MALE; NONHUMAN; PLANT ROOT; PUERARIA; RAT; TUBE FEEDING; WISTAR RAT;

ANIMALS; DRUGS, CHINESE HERBAL; ETHANOL; INTESTINAL MUCOSA; INTESTINE, SMALL; LIVER; LIVER DISEASES, ALCOHOLIC; MALE; MODELS, ANIMAL; PERMEABILITY; PHYTOTHERAPY; PLANT ROOTS; PUERARIA; RATS; RATS, WISTAR;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 70350302336     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.08.044     Document Type: Article

References (30)

1. Anderson J.M., and Van Itallie C.M. Tight junctions and the molecular basis for regulation of paracellular permeability. The American Journal of Physiology 269 (1995) G467-G475
2. Arao T., Udayama M., Kinjo J., and Nohara T. Preventive effects of saponins from the Pueraria lobata root on in vitro immunological liver injury of rat primary hepatocyte cultures. Planta Medica 64 (1998) 413-416
3. Arao T., Udayama M., Kinjo J., Nohara T., Funakoshi T., and Kojima S. Preventive effects of saponins from puerariae radix (the root of Pueraria lobata Ohwi) on in vitro immunological injury of rat primary hepatocyte cultures. Biological & Pharmaceutical Bulletin 20 (1997) 988-991
4. Atkinson K.J., and Rao R.K. Role of protein tyrosine phosphorylation in acetaldehyde-induced disruption of epithelial tight junctions. American Journal of Physiology-Gastrointestinal and Liver Physiology 280 (2001) G1280-G1288
5. Dinda P.K., Kossev P., Beck I.T., and Buell M.G. Role of xanthine oxidase-derived oxidants and leukocytes in ethanol-induced jejunal mucosal injury. Digestive Diseases and Sciences 41 (1996) 2461-2470
6. Ezzell R.M., Carter E.A., Yarmush M.L., and Tompkins R.G. Thermal injury-induced changes in the rat intestine brush border cytoskeleton. Surgery 114 (1993) 591-597
7. Fan Y., Wu D.Z., Gong Y.Q., Zhou J.Y., and Hu Z.B. Effects of calycosin on the impairment of barrier function induced by hypoxia in human umbilical vein endothelial cells. European Journal of Pharmacology 481 (2003) 33-40
8. Ferrier L., Berard F., Debrauwer L., Chabo C., Langella P., Bueno L., and Fioramonti J. Impairment of the intestinal barrier by ethanol involves enteric microflora and mast cell activation in rodents. The American Journal of Pathology 168 (2006) 1148-1154
9. French S.W., Miyamoto K., and Tsukamoto H. Ethanol-induced hepatic fibrosis in the rat: role of the amount of dietary fat. Alcoholism, Clinical and Experimental Research 10 (1986) 13S-19S
10. Hashimoto N., and Ohyanagi H. Effect of acute portal hypertension on gut mucosa. Hepato-Gastroenterology 49 (2002) 1567-1570
11. Hollander D. Crohn's disease-a permeability disorder of the tight junction?. Gut 29 (1988) 1621-1624
12. Keshavarzian A., Choudhary S., Holmes E.W., Yong S., Banan A., Jakate S., and Fields J.Z. Preventing gut leakiness by oats supplementation ameliorates alcohol-induced liver damage in rats. The Journal of Pharmacology and Experimental Therapeutics 299 (2001) 442-448
13. Keshavarzian A., Fields J.Z., Vaeth J., and Holmes E.W. The differing effects of acute and chronic alcohol on gastric and intestinal permeability. The American Journal of Gastroenterology 89 (1994) 2205-2211
14. Keung W.M., Klyosov A.A., and Vallee B.L. Daidzin inhibits mitochondrial aldehyde dehydrogenase and suppresses ethanol intake of Syrian golden hamsters. Proceedings of the National Academy of Sciences of the United States of America 94 (1997) 1675-1679
15. Keung W.M., and Vallee B.L. Daidzin and daidzein suppress free-choice ethanol intake by Syrian golden hamsters. Proceedings of the National Academy of Sciences of the United States of America 90 (1993) 10008-10012
16. Keung W.M., and Vallee B.L. Kudzu root: an ancient Chinese source of modern antidipsotropic agents. Phytochemistry 47 (1998) 499-506
17. Lambert J.C., Zhou Z., Wang L., Song Z., McClain C.J., and Kang Y.J. Prevention of alterations in intestinal permeability is involved in zinc inhibition of acute ethanol-induced liver damage in mice. The Journal of Pharmacology and Experimental Therapeutics 305 (2003) 880-886
18. Lee J.S. Supplementation of Pueraria radix water extract on changes of antioxidant enzymes and lipid profile in ethanol-treated rats. Clinica Chimica Acta: International Journal of Clinical Chemistry 347 (2004) 121-128
19. Lee M.K., Cho S.Y., Jang J.Y., Cho M.S., Jeon S.M., Jang M.K., Kim M.J., and Park Y.B. Effects of Puerariae Flos and Puerariae radix extracts on antioxidant enzymes in ethanol-treated rats. The American Journal of Chinese Medicine 29 (2001) 343-354
20. Levitt M.D., Doizaki W., and Levine A.S. Hypothesis: metabolic activity of the colonic bacteria influences organ injury from ethanol. Hepatology 2 (1982) 598-600
21. Lin R.C., and Li T.K. Effects of isoflavones on alcohol pharmacokinetics and alcohol-drinking behavior in rats. The American Journal of Clinical Nutrition 68 (1998) 1512S-1515S
22. Ma T.Y., Nguyen D., Bui V., Nguyen H., and Hoa N. Ethanol modulation of intestinal epithelial tight junction barrier. The American Journal of Physiology 276 (1999) G965-G974
23. Madara J.L. Loosening tight junctions. Lessons from the intestine. The Journal of Clinical Investigation 83 (1989) 1089-1094
24. Mathurin P., Deng Q.G., Keshavarzian A., Choudhary S., Holmes E.W., and Tsukamoto H. Exacerbation of alcoholic liver injury by enteral endotoxin in rats. Hepatology 32 (2000) 1008-1017
25. Nordmann R., Ribiere C., and Rouach H. Implication of free radical mechanisms in ethanol-induced cellular injury. Free Radical Biology & Medicine 12 (1992) 219-240
26. Ohshima Y., Okuyama T., Takahashi K., Takizawa T., and Shibata S. Isolation and high performance liquid chromatography (HPLC) of isoflavonoids from the Pueraria root. Planta Medica 54 (1988) 250-254
27. Rao R.K., Seth A., and Sheth P. Recent advances in alcoholic liver disease I. Role of intestinal permeability and endotoxemia in alcoholic liver disease. American Journal of Physiology-Gastrointestinal and Liver Physiology 286 (2004) G881-884
28. Sun Z., Wang X., and Andersson R. Role of intestinal permeability in monitoring mucosal barrier function. History, methodology, and significance of pathophysiology. Digestive Surgery 15 (1998) 386-397
29. Tan X.D., Chang H., Qu X.W., Caplan M., Gonzalez-Crussi F., and Hsueh W. Platelet-activating factor increases mucosal permeability in rat intestine via tyrosine phosphorylation of E-cadherin. British Journal of Pharmacology 129 (2000) 1522-1529
30. Zhang S., Ji G., and Liu J. Reversal of chemical-induced liver fibrosis in Wistar rats by puerarin. The Journal of Nutritional Biochemistry 17 (2006) 485-491