Trans-11 vaccenic acid reduces hepatic lipogenesis and chylomicron secretion in JCR: LA-cp rats

Journal of Nutrition

Volumn 139, Issue 11, 2009, Pages 2049-2054

  Wang, Ye ^a   Jacome Sosa, M Miriam ^a   Ruth, Megan R ^a   Goruk, Sue D ^a   Reaney, Martin J ^b   Glimm, David R ^a   Wright, David C ^a   Vine, Donna F ^a   Field, Catherine J ^a   Proctor, Spencer D ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; APOLIPOPROTEIN B48; CHYLOMICRON; FATTY ACID; FATTY ACID SYNTHASE; HAPTOGLOBIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRANS 11 VACCENIC ACID; TRIACYLGLYCEROL; TRIOLEIN; UNCLASSIFIED DRUG; VACCENIC ACID;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD LEVEL; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIET SUPPLEMENTATION; FOOD INTAKE; INTESTINE; INTESTINE SECRETION; LIPID BLOOD LEVEL; LIPID COMPOSITION; LIPOGENESIS; LIPOPROTEIN BLOOD LEVEL; LIVER; LIVER LEVEL; MALE; MESENTERY LYMPH NODE; NONHUMAN; ORGAN WEIGHT; POSTPRANDIAL STATE; RAT; TRIACYLGLYCEROL BLOOD LEVEL;

ACETYL-COA CARBOXYLASE; ANIMALS; APOLIPOPROTEIN B-48; BODY WEIGHT; CHYLOMICRONS; DIET; EMULSIONS; ENERGY INTAKE; FATTY ACID SYNTHETASE COMPLEX; INFUSIONS, PARENTERAL; LIPOGENESIS; LIVER; LYMPH; OBESITY; OLEIC ACIDS; ORGAN SIZE; RATS; RATS, INBRED STRAINS; TRIGLYCERIDES; TRIOLEIN;

ANIMALIA; RATTUS;

EID: 70350279317     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.109.109488     Document Type: Article

References (48)

1. Han SN, Leka LS, Lichtenstein AH, Ausman LM, Schaefer EJ, Meydani SN. Effect of hydrogenated and saturated, relative to polyunsaturated, fat on immune and inflammatory responses of adults with moderate hypercholesterolemia. J Lipid Res. 2002;43:445-452
2. Lichtenstein AH, Ausman LM, Jalbert SM, Schaefer EJ. Effects of different forms of dietary hydrogenated fats on serum lipoprotein cholesterol levels. N Engl J Med. 1999;340:1933-1940
3. Lichtenstein AH, Erkkila AT, Lamarche B, Schwab US, Jalbert SM, Ausman LM. Influence of hydrogenated fat and butter on CVD risk factors: remnant-like particles, glucose and insulin, blood pressure and C-reactive protein. Atherosclerosis. 2003;171:97-107. (Pubitemid 37464634)
4. Judd JT, Baer DJ, Clevidence BA, Muesing RA, Chen SC, Weststrate JA, Meijer GW, Wittes J, Lichtenstein AH, et al. Effects of margarine compared with those of butter on blood lipid profiles related to cardiovascular disease risk factors in normolipemic adults fed controlled diets. Am J Clin Nutr. 1998;68:768-777 (Pubitemid 28471059)
5. Judd JT, Clevidence BA, Muesing RA, Wittes J, Sunkin ME, Podczasy JJ. Dietary trans fatty acids: effects on plasma lipids and lipoproteins of healthy men and women. Am J Clin Nutr. 1994;59:861-868 (Pubitemid 24112524)
6. Judd JT, Baer DJ, Clevidence BA, Kris-Etherton P, Muesing RA, Iwane M. Dietary cis and trans monounsaturated and saturated FA and plasma lipids and lipoproteins in men. Lipids. 2002;37:123-131 (Pubitemid 34213977)
7. Lock AL, Bauman DE. Modifying milk fat composition of dairy cows to enhance fatty acids beneficial to human health. Lipids. 2004;39:1197-1206
8. Cruz-Hernandez C, Kramer JK, Kennelly JJ, Glimm DR, Sorensen BM, Okine EK, Goonewardene LA, Weselake RJ. Evaluating the conjugated linoleic acid and trans 18:1 isomers in milk fat of dairy cows fed increasing amounts of sunflower oil and a constant level of fish oil. J Dairy Sci. 2007;90:3786-3801 (Pubitemid 350045258)
9. Palmquist DL, Lock AL, Shingfield KJ, Bauman DE. Biosynthesis of conjugated linoleic acid in ruminants and humans. Adv Food Nutr Res. 2005;50:179-217.
10. Lock AL, Corl BA, Barbano DM, Bauman DE, Ip C. The anticarcinogenic effect of trans-11 18:1 is dependent on its conversion to cis-9, trans-11 CLA by delta9-desaturase in rats. J Nutr. 2004;134:2698-2704
11. Turpeinen AM, Mutanen M, Aro A, Salminen I, Basu S, Palmquist DL, Griinari JM. Bioconversion of vaccenic acid to conjugated linoleic acid in humans. Am J Clin Nutr. 2002;76:504-510 (Pubitemid 34920825)
12. Motard-Belanger A, Charest A, Grenier G, Paquin P, Chouinard Y, Lemieux S, Couture P, Lamarche B. Study of the effect of trans fatty acids from ruminants on blood lipids and other risk factors for cardiovascular disease. Am J Clin Nutr. 2008;87:593-599
13. Chardigny JM, Destaillats F, Malpuech-Brugere C, Moulin J, Bauman DE, Lock AL, Barbano DM, Mensink RP, Bezelgues JB, et al. Do trans fatty acids from industrially produced sources and from natural sources have the same effect on cardiovascular disease risk factors in healthy subjects? Results of the trans Fatty Acids Collaboration (TRANSFACT) study. Am J Clin Nutr. 2008;87:558-566
14. Bauchart D, Roy A, Lorenz S, Chardigny JM, Ferlay A, Gruffat D, Sebedio JL, Chilliard Y, Durand D. Butters varying in trans 18:1 and cis-9,trans-11 conjugated linoleic acid modify plasma lipoproteins in the hypercholesterolemic rabbit. Lipids. 2007;42:123-133 (Pubitemid 351912043)
15. Lock AL, Horne CA, Bauman DE, Salter AM. Butter naturally enriched in conjugated linoleic acid and vaccenic acid alters tissue fatty acids and improves the plasma lipoprotein profile in cholesterol-fed hamsters. J Nutr. 2005;135:1934-1939
16. Faulconnier Y, Roy A, Ferlay A, Chardigny JM, Durand D, Lorenz S, Gruffat D, Chilliard Y. Effect of dietary supply of butters rich either in trans-10-18: 1 or in trans-11-18: 1 plus cis-9, trans-11-18: 2 on rabbit adipose tissue and liver lipogenic activities. Br J Nutr. 2006;96:461-468
17. Tyburczy C, Major C, Lock AL, Destaillat F, Lawrence P, Brenna JT, Salter AM, Bauman DE. Individual trans octadecenoic acids and partially hydrogenated vegetable oil differentially affect hepatic lipid and lipoprotein metabolism in golden Syrian hamsters. J Nutr. 2009;139:257-263
18. Wang Y, Lu J, Ruth MR, Goruk SD, Reaney MJ, Glimm DR, Vine DF, Field CJ, Proctor SD. Trans-11 vaccenic acid dietary supplementation induces hypolipidemic effects in JCR:LA-cp rats. J Nutr. 2008;138:2117-2122
19. Koletsky S. Obese spontaneously hypertensive rats: a model for study of atherosclerosis. Exp Mol Pathol. 1973;19:53-60.
20. Elam MB, Wilcox HG, Cagen LM, Deng X, Raghow R, Kumar P, Heimberg M, Russell JC. Increased hepatic VLDL secretion, lipogenesis, and SREBP-1 expression in the corpulent JCR:LA-cp rat. J Lipid Res. 2001;42:2039-2048 (Pubitemid 34001053)
21. Mangat R, Su J, Scott PG, Russell JC, Vine DF, Proctor SD. Chylomicron and apoB48 metabolism in the JCR:LA corpulent rat, a model for the metabolic syndrome. Biochem Soc Trans. 2007;35:477-481 (Pubitemid 46975056)
22. Russell JC, Graham S, Hameed M. Abnormal insulin and glucose metabolism in the JCR:LA-corpulent rat. Metabolism. 1994;43:538-543 (Pubitemid 24145457)
23. Russell JC, Graham SE, Richardson M. Cardiovascular disease in the JCR:LA-cp rat. Mol Cell Biochem. 1998;188:113-126
24. Russell JC, Koeslag DG, Amy RM, Dolphin PJ. Plasma lipid secretion and clearance in hyperlipidemic JCR:LA-corpulent rats. Arteriosclerosis. 1989;9:869-876
25. Vance JE, Russell JC. Hypersecretion of VLDL, but not HDL, by hepatocytes from the JCR:LA-corpulent rat. J Lipid Res. 1990;31:1491-1501
26. Vine DF, Takechi R, Russell JC, Proctor SD. Impaired postprandial apolipoprotein-B48 metabolism in the obese, insulin-resistant JCR:LA-cp rat: increased atherogenicity for the metabolic syndrome. Atherosclerosis. 2007;190:282-290 (Pubitemid 46074043)
27. Vine DF, Glimm DR, Proctor SD. Intestinal lipid transport and chylomicron production: possible links to exacerbated atherogenesis in a rodent model of the metabolic syndrome. Atherosclerosis. 2008;9:69-76.
28. Russell JC, Amy RM, Graham SE, Dolphin PJ, Wood GO, Bar-Tana J. Inhibition of atherosclerosis and myocardial lesions in the JCR:LA-cp rat by beta, beta'-tetramethylhexadecanedioic acid (MEDICA 16). Arterioscler Thromb Vasc Biol. 1995;15:918-923
29. Robinson LE, Field CJ. Dietary long-chain (n-3) fatty acids facilitate immune cell activation in sedentary, but not exercise-trained rats. J Nutr. 1998;128:498-504.
30. Swain MLBB. Formation of traces of conjugated tetraenoic and trienoic constitutents in autoxidized linolenic and linoleic acids and vegetable oils during alkali-isomerization. JAOCS. 1949;26:272-277
31. Qin Y, Dalen KT, Gustafsson JA, Nebb HI. Regulation of hepatic fatty acid elongase 5 by LXRalpha-SREBP-1c. Biochim Biophys Acta. 2009;1791:140-147
32. Weiser MM. Intestinal epithelial cell surface membrane glycoprotein synthesis. II. Glycosyltransferases and endogenous acceptors of the undifferentiated cell surface membrane. J Biol Chem. 1973;248:2542-2548
33. Vine DF, Croft KD, Beilin LJ, Mamo JC. Absorption of dietary cholesterol oxidation products and incorporation into rat lymph chylomicrons. Lipids. 1997;32:887-893
34. Cooper-DeHoff RM, Pepine CJ. Metabolic syndrome and cardiovascular disease: challenges and opportunities. Clin Cardiol. 2007;30:593-597 (Pubitemid 350293340)
35. Falko JM, Moser RJ, Meis SB, Caulin-Glaser T. Cardiovascular disease risk of type 2 diabetes mellitus and metabolic syndrome: focus on aggressive management of dyslipidemia. Curr Diabetes Rev. 2005;1:127-135
36. Gupta S, Gupta BM. Metabolic syndrome: diabetes and cardiovascular disease. Indian Heart J. 2006;58:149-152 (Pubitemid 44533124)
37. Jiamsripong P, Mookadam M, Honda T, Khandheria BK, Mookadam F. The metabolic syndrome and cardiovascular disease: Part I. Prev Cardiol. 2008;11:155-161
38. Rana JS, Nieuwdorp M, Jukema JW, Kastelein JJ. Cardiovascular metabolic syndrome: an interplay of obesity, inflammation, diabetes and coronary heart disease. Diabetes Obes Metab. 2007;9:218-232 (Pubitemid 46502040)
39. Meijer GW, van Tol A, van Berkel TJ, Weststrate JA. Effect of dietary elaidic versus vaccenic acid on blood and liver lipids in the hamster. Atherosclerosis. 2001;157:31-40.
40. Tholstrup T, Raff M, Basu S, Nonboe P, Sejrsen K, Straarup EM. Effects of butter high in ruminant trans and monounsaturated fatty acids on lipoproteins, incorporation of fatty acids into lipid classes, plasma C-reactive protein, oxidative stress, hemostatic variables, and insulin in healthy young men. Am J Clin Nutr. 2006;83:237-243 (Pubitemid 44713183)
41. Libby P, Ridker PM, Maseri A. Inflammation and atherosclerosis. Circulation. 2002;105:1135-1143
42. Engstrom G, Lind P, Hedblad B, Stavenow L, Janzon L, Lindgarde F. Long-term effects of inflammation-sensitive plasma proteins and systolic blood pressure on incidence of stroke. Stroke. 2002;33:2744-2749 (Pubitemid 35462837)
43. Maresca G, Di Blasio A, Marchioli R, Di Minno G. Measuring plasma fibrinogen to predict stroke and myocardial infarction: an update. Arterioscler Thromb Vasc Biol. 1999;19:1368-1377 (Pubitemid 29263005)
44. Balestrieri M, Cigliano L, Simone ML, Dale B, Abrescia P. Haptoglobin inhibits lecithin-cholesterol acyltransferase in human ovarian follicular fluid. Mol Reprod Dev. 2001;59:186-191 (Pubitemid 32391244)
45. Cigliano L, Maresca B, Salvatore A, Nino M, Monfrecola G, Ayala F, Carlucci A, Pugliese RC, Pedone C, et al. Haptoglobin from psoriatic patients exhibits decreased activity in binding haemoglobin and inhibiting lecithin-cholesterol acyltransferase activity. J Eur Acad Dermatol Venereol. 2008;22:417-425
46. Jump DB. N-3 polyunsaturated fatty acid regulation of hepatic gene transcription. Curr Opin Lipidol. 2008;19:242-247
47. Jump DB, Botolin D, Wang Y, Xu J, Demeure O, Christian B. Docosahexaenoic acid (DHA) and hepatic gene transcription. Chem Phys Lipids. 2008;153:3-13.
48. Lampen A, Leifheit M, Voss J, Nau H. Molecular and cellular effects of cis-9, trans-11-conjugated linoleic acid in enterocytes: effects on proliferation, differentiation, and gene expression. Biochim biophys acta 2005;1735:30-40. (Pubitemid 40814511)