메뉴 건너뛰기




Volumn 16, Issue 3, 2009, Pages 265-274

Atorvastatin increases endoglin, SMAD2, phosphorylated SMAD2/3 and eNOS expression in ApoE/LDLR double knockout mice

Author keywords

ApoE LDLR double knockout mice; Atorvastatin; Endoglin; eNOS; Phosphorylated SMAD2 3; SMAD2

Indexed keywords

APOLIPOPROTEIN E; ATORVASTATIN; CHOLESTEROL; ENDOGLIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; SMAD2 PROTEIN; SMAD3 PROTEIN; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

EID: 70350225475     PISSN: 13403478     EISSN: 18803873     Source Type: Journal    
DOI: 10.5551/jat.E745     Document Type: Article
Times cited : (16)

References (32)
  • 2
    • 0030071563 scopus 로고    scopus 로고
    • Endoglin is a component of the transforming growth factor (TGF)-beta receptor complex of human pre-B leukemic cells
    • Zhang H, Shaw AR, Mak A, Letarte M: Endoglin is a component of the transforming growth factor (TGF)-beta receptor complex of human pre-B leukemic cells. J Immunol, 1996; 156:564-573
    • (1996) J Immunol , vol.156 , pp. 564-573
    • Zhang, H.1    Shaw, A.R.2    Mak, A.3    Letarte, M.4
  • 3
    • 0034730108 scopus 로고    scopus 로고
    • Effect of chronic treatment with the inducible nitric oxide synthase inhibitor N-iminoethyl-L-lysine or with L-arginine on progression of coronary and aortic atherosclerosis in hypercholesterolemic rabbits
    • Behr-Roussel D, Rupin A, Simonet S, Bonhomme E, Coumailleau S, Cordi A, Serkiz B, Fabiani JN, Verbeuren TJ: Effect of chronic treatment with the inducible nitric oxide synthase inhibitor N-iminoethyl-L-lysine or with L-arginine on progression of coronary and aortic atherosclerosis in hypercholesterolemic rabbits. Circulation, 2000; 102:1033-1038
    • (2000) Circulation , vol.102 , pp. 1033-1038
    • Behr-Roussel, D.1    Rupin, A.2    Simonet, S.3    Bonhomme, E.4    Coumailleau, S.5    Cordi, A.6    Serkiz, B.7    Fabiani, J.N.8    Verbeuren, T.J.9
  • 4
    • 0034496590 scopus 로고    scopus 로고
    • Endoglin, a TGF-beta receptor-associated protein, is expressed by smooth muscle cells in human atherosclerotic plaques
    • Conley BA, Smith JD, Guerrero-Esteo M, Bernabeu C, Vary CP: Endoglin, a TGF-beta receptor-associated protein, is expressed by smooth muscle cells in human atherosclerotic plaques. Atherosclerosis, 2000; 153:323-335
    • (2000) Atherosclerosis , vol.153 , pp. 323-335
    • Conley, B.A.1    Smith, J.D.2    Guerrero-Esteo, M.3    Bernabeu, C.4    Vary, C.P.5
  • 8
    • 33746533646 scopus 로고    scopus 로고
    • Significant expression of endoglin (CD105), TGFbeta-1 and TGFbeta R-2 in the atherosclerotic aorta: An immunohistological study
    • Piao M, Tokunaga O: Significant expression of endoglin (CD105), TGFbeta-1 and TGFbeta R-2 in the atherosclerotic aorta: an immunohistological study. J Atheroscler Thromb, 2006; 13:82-89
    • (2006) J Atheroscler Thromb , vol.13 , pp. 82-89
    • Piao, M.1    Tokunaga, O.2
  • 10
    • 3042730959 scopus 로고    scopus 로고
    • eNOS at a glance
    • Sessa WC: eNOS at a glance. J Cell Sci, 2004; 117:2427-2429
    • (2004) J Cell Sci , vol.117 , pp. 2427-2429
    • Sessa, W.C.1
  • 12
    • 2642536741 scopus 로고    scopus 로고
    • Inflammation, immunity, and HMG-CoA reductase inhibitors: Statins as antiinflammatory agents?
    • Schönbeck U, Libby P: Inflammation, immunity, and HMG-CoA reductase inhibitors: statins as antiinflammatory agents? Circulation, 2004; 109:II 18-26
    • (2004) Circulation , vol.109 , Issue.II , pp. 18-26
    • Schönbeck, U.1    Libby, P.2
  • 14
    • 34347334674 scopus 로고    scopus 로고
    • Mevastatin increases eNO synthase expression and inhibits lipid peroxidation in human endothelial cells
    • Schalkwijk CG, van Dam B, Stehouwer CD, van Hinsbergh VW: Mevastatin increases eNO synthase expression and inhibits lipid peroxidation in human endothelial cells. Clin Hemorheol Microcirc, 2007; 37:179-184
    • (2007) Clin Hemorheol Microcirc , vol.37 , pp. 179-184
    • Schalkwijk, C.G.1    van Dam, B.2    Stehouwer, C.D.3    van Hinsbergh, V.W.4
  • 20
    • 0033673419 scopus 로고    scopus 로고
    • Endoglin is overexpressed after arterial injury and is required for transforming growth factor-beta-induced inhibition of smooth muscle cell migration
    • Ma X, Labinaz M, Goldstein J, Miller H, Keon WJ, Letarte M, O'Brien E: Endoglin is overexpressed after arterial injury and is required for transforming growth factor-beta-induced inhibition of smooth muscle cell migration. Arterioscler Thromb Vasc Biol, 2000; 20:2546-2552
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2546-2552
    • Ma, X.1    Labinaz, M.2    Goldstein, J.3    Miller, H.4    Keon, W.J.5    Letarte, M.6    O'Brien, E.7
  • 23
    • 16444373524 scopus 로고    scopus 로고
    • A role for endoglin in coupling eNOS activity and regulating vascular tone revealed in hereditary hemorrhagic telangiectasia
    • Toporsian M, Gros R, Kabir MG, Vera S, Govindaraju K, Eidelman DH, Husain M, Letarte M: A role for endoglin in coupling eNOS activity and regulating vascular tone revealed in hereditary hemorrhagic telangiectasia. Circ Res, 2005; 96:684-692
    • (2005) Circ Res , vol.96 , pp. 684-692
    • Toporsian, M.1    Gros, R.2    Kabir, M.G.3    Vera, S.4    Govindaraju, K.5    Eidelman, D.H.6    Husain, M.7    Letarte, M.8
  • 24
    • 33746829275 scopus 로고    scopus 로고
    • Transforming growth factor-betas and vascular disorders
    • Bobik A: Transforming growth factor-betas and vascular disorders. Arterioscler Thromb Vasc Biol, 2006; 26:1712-1720
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1712-1720
    • Bobik, A.1
  • 25
    • 39149086751 scopus 로고    scopus 로고
    • Cholesterol modulates cellular TGF-beta responsiveness by altering TGF-beta binding to TGF-beta receptors
    • Chen CL, Huang SS, Huang JS: Cholesterol modulates cellular TGF-beta responsiveness by altering TGF-beta binding to TGF-beta receptors. J Cell Physiol, 2008; 215:223-233
    • (2008) J Cell Physiol , vol.215 , pp. 223-233
    • Chen, C.L.1    Huang, S.S.2    Huang, J.S.3
  • 26
    • 36248952556 scopus 로고    scopus 로고
    • Cholesterol suppresses cellular TGF-beta responsiveness: Implications in atherogenesis
    • Chen CL, Liu IH, Fliesler SJ, Han X, Huang SS, Huang JS: Cholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesis. J Cell Sci, 2007; 120:3509-3521
    • (2007) J Cell Sci , vol.120 , pp. 3509-3521
    • Chen, C.L.1    Liu, I.H.2    Fliesler, S.J.3    Han, X.4    Huang, S.S.5    Huang, J.S.6
  • 27
    • 0036773855 scopus 로고    scopus 로고
    • The role of transforming growth factor beta in atherosclerosis: Novel insights and future perspectives
    • Mallat Z, Tedgui A: The role of transforming growth factor beta in atherosclerosis: novel insights and future perspectives. Curr Opin Lipidol, 2002; 13:523-529
    • (2002) Curr Opin Lipidol , vol.13 , pp. 523-529
    • Mallat, Z.1    Tedgui, A.2
  • 28
    • 33644907733 scopus 로고    scopus 로고
    • Role of transforming growth factor-beta1/Smads in regulating vascular inflammation and atherogenesis
    • Feinberg MW, Jain MK: Role of transforming growth factor-beta1/Smads in regulating vascular inflammation and atherogenesis. Panminerva Med, 2005; 47:169-186
    • (2005) Panminerva Med , vol.47 , pp. 169-186
    • Feinberg, M.W.1    Jain, M.K.2
  • 30
    • 21644452716 scopus 로고    scopus 로고
    • Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex
    • Blanco FJ, Santibanez JF, Guerrero-Esteo M, Langa C, Vary CP, Bernabeu C: Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex. J Cell Physiol, 2005; 204:574-584
    • (2005) J Cell Physiol , vol.204 , pp. 574-584
    • Blanco, F.J.1    Santibanez, J.F.2    Guerrero-Esteo, M.3    Langa, C.4    Vary, C.P.5    Bernabeu, C.6
  • 31
    • 0033527664 scopus 로고    scopus 로고
    • Oxidized low density lipoprotein displaces endothelial nitric-oxide synthase (eNOS) from plasmalemmal caveolae and impairs eNOS activation
    • Blair A, Shaul PW, Yuhanna IS, Conrad PA, Smart EJ: Oxidized low density lipoprotein displaces endothelial nitric-oxide synthase (eNOS) from plasmalemmal caveolae and impairs eNOS activation. J Biol Chem, 1999; 274:32512-32519
    • (1999) J Biol Chem , vol.274 , pp. 32512-32519
    • Blair, A.1    Shaul, P.W.2    Yuhanna, I.S.3    Conrad, P.A.4    Smart, E.J.5
  • 32
    • 0032584177 scopus 로고    scopus 로고
    • Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors
    • Laufs U, La Fata V, Plutzky J, Liao JK: Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors. Circulation, 1998; 97:1129-1135
    • (1998) Circulation , vol.97 , pp. 1129-1135
    • Laufs, U.1    La Fata, V.2    Plutzky, J.3    Liao, J.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.