메뉴 건너뛰기




Volumn 394, Issue 1, 2009, Pages 29-45

Regulated Expression of the α Isoform of the Human Thromboxane A2 Receptor during Megakaryocyte Differentiation: A Coordinated Role for WT1, Egr1, and Sp1

Author keywords

Egr1; megakaryocytic differentiation; Sp1; thromboxane receptor gene; WT1

Indexed keywords

BINDING PROTEIN; CIS ACTING ELEMENT; EARLY GROWTH RESPONSE FACTOR 1; ISOPROTEIN; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; THROMBOXANE; THROMBOXANE A2 RECEPTOR; TRANSCRIPTION FACTOR SP1; WT1 PROTEIN;

EID: 70350211070     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2009.09.007     Document Type: Article
Times cited : (15)

References (51)
  • 1
    • 0032823306 scopus 로고    scopus 로고
    • Prostanoid receptors: structures, properties, and functions
    • Narumiya S., Sugimoto Y., and Ushikubi F. Prostanoid receptors: structures, properties, and functions. Physiol. Rev. 79 (1999) 1193-1226
    • (1999) Physiol. Rev. , vol.79 , pp. 1193-1226
    • Narumiya, S.1    Sugimoto, Y.2    Ushikubi, F.3
  • 2
    • 0018398906 scopus 로고
    • Arachidonic acid metabolites and the interactions between platelets and blood-vessel walls
    • Moncada S., and Vane J.R. Arachidonic acid metabolites and the interactions between platelets and blood-vessel walls. N. Engl. J. Med. 300 (1979) 1142-1147
    • (1979) N. Engl. J. Med. , vol.300 , pp. 1142-1147
    • Moncada, S.1    Vane, J.R.2
  • 3
    • 0026060120 scopus 로고
    • Characterization of thromboxane A2/prostaglandin H2 receptors of various tissues using a new radioiodinated thromboxane A2/prostaglandin H2 mimetic, I-BOP
    • Morinelli T.A., Naka M., Masuda A., Oatis Jr. J.E., Okwu A.K., Mais D.E., et al. Characterization of thromboxane A2/prostaglandin H2 receptors of various tissues using a new radioiodinated thromboxane A2/prostaglandin H2 mimetic, I-BOP. Adv. Prostaglandin, Thromboxane, Leukotriene Res. 21A (1991) 331-337
    • (1991) Adv. Prostaglandin, Thromboxane, Leukotriene Res. , vol.21 A , pp. 331-337
    • Morinelli, T.A.1    Naka, M.2    Masuda, A.3    Oatis Jr., J.E.4    Okwu, A.K.5    Mais, D.E.6
  • 5
    • 0018196543 scopus 로고
    • Prostacyclin and thromboxane A2 biosynthesis capacities of heart, arteries and platelets at various stages of experimental atherosclerosis in rabbits
    • Gryglewski R.J., Dembinska-Kiec A., Zmuda A., and Gryglewska T. Prostacyclin and thromboxane A2 biosynthesis capacities of heart, arteries and platelets at various stages of experimental atherosclerosis in rabbits. Atherosclerosis 31 (1978) 385-394
    • (1978) Atherosclerosis , vol.31 , pp. 385-394
    • Gryglewski, R.J.1    Dembinska-Kiec, A.2    Zmuda, A.3    Gryglewska, T.4
  • 6
    • 0019504566 scopus 로고
    • Release of prostaglandins and thromboxane into the coronary circulation in patients with ischemic heart disease
    • Hirsh P.D., Hillis L.D., Campbell W.B., Firth B.G., and Willerson J.T. Release of prostaglandins and thromboxane into the coronary circulation in patients with ischemic heart disease. N. Engl. J. Med. 304 (1981) 685-691
    • (1981) N. Engl. J. Med. , vol.304 , pp. 685-691
    • Hirsh, P.D.1    Hillis, L.D.2    Campbell, W.B.3    Firth, B.G.4    Willerson, J.T.5
  • 7
    • 0028296680 scopus 로고
    • A comparative evaluation of thromboxane receptor blockade, thromboxane synthase inhibition and both in animal models of arterial thrombosis
    • Salvati P., Dho L., Ukmar G., Vaga L., Rimoldi O., and Patrono C. A comparative evaluation of thromboxane receptor blockade, thromboxane synthase inhibition and both in animal models of arterial thrombosis. J. Pharmacol. Exp. Ther. 269 (1994) 238-245
    • (1994) J. Pharmacol. Exp. Ther. , vol.269 , pp. 238-245
    • Salvati, P.1    Dho, L.2    Ukmar, G.3    Vaga, L.4    Rimoldi, O.5    Patrono, C.6
  • 8
    • 0027484210 scopus 로고
    • Characterization and chromosomal mapping of the human thromboxane A2 receptor gene
    • Nusing R.M., Hirata M., Kakizuka A., Eki T., Ozawa K., and Narumiya S. Characterization and chromosomal mapping of the human thromboxane A2 receptor gene. J. Biol. Chem. 268 (1993) 25253-25259
    • (1993) J. Biol. Chem. , vol.268 , pp. 25253-25259
    • Nusing, R.M.1    Hirata, M.2    Kakizuka, A.3    Eki, T.4    Ozawa, K.5    Narumiya, S.6
  • 9
    • 0027936171 scopus 로고
    • Alternative splicing produces a divergent cytoplasmic tail in the human endothelial thromboxane A2 receptor
    • Raychowdhury M.K., Yukawa M., Collins L.J., McGrail S.H., Kent K.C., and Ware J.A. Alternative splicing produces a divergent cytoplasmic tail in the human endothelial thromboxane A2 receptor. J. Biol. Chem. 269 (1994) 19256-19261
    • (1994) J. Biol. Chem. , vol.269 , pp. 19256-19261
    • Raychowdhury, M.K.1    Yukawa, M.2    Collins, L.J.3    McGrail, S.H.4    Kent, K.C.5    Ware, J.A.6
  • 10
    • 0029664751 scopus 로고    scopus 로고
    • Two thromboxane A2 receptor isoforms in human platelets. Opposite coupling to adenylyl cyclase with different sensitivity to Arg60 to Leu mutation
    • Hirata T., Ushikubi F., Kakizuka A., Okuma M., and Narumiya S. Two thromboxane A2 receptor isoforms in human platelets. Opposite coupling to adenylyl cyclase with different sensitivity to Arg60 to Leu mutation. J. Clin. Invest. 97 (1996) 949-956
    • (1996) J. Clin. Invest. , vol.97 , pp. 949-956
    • Hirata, T.1    Ushikubi, F.2    Kakizuka, A.3    Okuma, M.4    Narumiya, S.5
  • 11
    • 0346435101 scopus 로고    scopus 로고
    • The alpha, but not the beta, isoform of the human thromboxane A2 receptor is a target for nitric oxide-mediated desensitization. Independent modulation of Tp alpha signaling by nitric oxide and prostacyclin
    • Reid H.M., and Kinsella B.T. The alpha, but not the beta, isoform of the human thromboxane A2 receptor is a target for nitric oxide-mediated desensitization. Independent modulation of Tp alpha signaling by nitric oxide and prostacyclin. J. Biol. Chem. 278 (2003) 51190-51202
    • (2003) J. Biol. Chem. , vol.278 , pp. 51190-51202
    • Reid, H.M.1    Kinsella, B.T.2
  • 12
    • 0034617213 scopus 로고    scopus 로고
    • The alpha, but not the beta, isoform of the human thromboxane A2 receptor is a target for prostacyclin-mediated desensitization
    • Walsh M.T., Foley J.F., and Kinsella B.T. The alpha, but not the beta, isoform of the human thromboxane A2 receptor is a target for prostacyclin-mediated desensitization. J. Biol. Chem. 275 (2000) 20412-20423
    • (2000) J. Biol. Chem. , vol.275 , pp. 20412-20423
    • Walsh, M.T.1    Foley, J.F.2    Kinsella, B.T.3
  • 13
    • 33748450161 scopus 로고    scopus 로고
    • Homologous desensitization of signalling by the beta (beta) isoform of the human thromboxane A2 receptor
    • Kelley-Hickie L.P., and Kinsella B.T. Homologous desensitization of signalling by the beta (beta) isoform of the human thromboxane A2 receptor. Biochim. Biophys. Acta 1761 (2006) 1114-1131
    • (2006) Biochim. Biophys. Acta , vol.1761 , pp. 1114-1131
    • Kelley-Hickie, L.P.1    Kinsella, B.T.2
  • 14
    • 0033605423 scopus 로고    scopus 로고
    • Internalization of the TXA2 receptor alpha and beta isoforms. Role of the differentially spliced COOH terminus in agonist-promoted receptor internalization
    • Parent J.L., Labrecque P., Orsini M.J., and Benovic J.L. Internalization of the TXA2 receptor alpha and beta isoforms. Role of the differentially spliced COOH terminus in agonist-promoted receptor internalization. J. Biol. Chem. 274 (1999) 8941-8948
    • (1999) J. Biol. Chem. , vol.274 , pp. 8941-8948
    • Parent, J.L.1    Labrecque, P.2    Orsini, M.J.3    Benovic, J.L.4
  • 15
    • 0031762633 scopus 로고    scopus 로고
    • Expression and tissue distribution of the mRNAs encoding the human thromboxane A2 receptor (TP) alpha and beta isoforms
    • Miggin S.M., and Kinsella B.T. Expression and tissue distribution of the mRNAs encoding the human thromboxane A2 receptor (TP) alpha and beta isoforms. Biochim. Biophys. Acta 1425 (1998) 543-559
    • (1998) Biochim. Biophys. Acta , vol.1425 , pp. 543-559
    • Miggin, S.M.1    Kinsella, B.T.2
  • 16
    • 0033613968 scopus 로고    scopus 로고
    • Phosphorylation of the thromboxane receptor alpha, the predominant isoform expressed in human platelets
    • Habib A., FitzGerald G.A., and Maclouf J. Phosphorylation of the thromboxane receptor alpha, the predominant isoform expressed in human platelets. J. Biol. Chem. 274 (1999) 2645-2651
    • (1999) J. Biol. Chem. , vol.274 , pp. 2645-2651
    • Habib, A.1    FitzGerald, G.A.2    Maclouf, J.3
  • 17
    • 0035982616 scopus 로고    scopus 로고
    • Characterization of the 5′ untranslated region of alpha and beta isoforms of the human thromboxane A2 receptor (TP). Differential promoter utilization by the TP isoforms
    • Coyle A.T., Miggin S.M., and Kinsella B.T. Characterization of the 5′ untranslated region of alpha and beta isoforms of the human thromboxane A2 receptor (TP). Differential promoter utilization by the TP isoforms. Eur. J. Biochem. 269 (2002) 4058-4073
    • (2002) Eur. J. Biochem. , vol.269 , pp. 4058-4073
    • Coyle, A.T.1    Miggin, S.M.2    Kinsella, B.T.3
  • 18
    • 14044251418 scopus 로고    scopus 로고
    • Characterization of promoter 3 of the human thromboxane A receptor gene. A functional AP-1 and octamer motif are required for basal promoter activity
    • Coyle A.T., and Kinsella B.T. Characterization of promoter 3 of the human thromboxane A receptor gene. A functional AP-1 and octamer motif are required for basal promoter activity. FEBS J. 272 (2005) 1036-1053
    • (2005) FEBS J. , vol.272 , pp. 1036-1053
    • Coyle, A.T.1    Kinsella, B.T.2
  • 19
    • 25444498564 scopus 로고    scopus 로고
    • 15-deoxy Delta12,14-prostaglandin J2 suppresses transcription by promoter 3 of the human thromboxane A2 receptor gene through peroxisome proliferator-activated receptor gamma in human erythroleukemia cells
    • Coyle A.T., O'Keeffe M.B., and Kinsella B.T. 15-deoxy Delta12,14-prostaglandin J2 suppresses transcription by promoter 3 of the human thromboxane A2 receptor gene through peroxisome proliferator-activated receptor gamma in human erythroleukemia cells. FEBS J. 272 (2005) 4754-4773
    • (2005) FEBS J. , vol.272 , pp. 4754-4773
    • Coyle, A.T.1    O'Keeffe, M.B.2    Kinsella, B.T.3
  • 20
    • 33645128230 scopus 로고    scopus 로고
    • Synthetic peroxisome proliferator-activated receptor gamma agonists rosiglitazone and troglitazone suppress transcription by promoter 3 of the human thromboxane A2 receptor gene in human erythroleukemia cells
    • Coyle A.T., and Kinsella B.T. Synthetic peroxisome proliferator-activated receptor gamma agonists rosiglitazone and troglitazone suppress transcription by promoter 3 of the human thromboxane A2 receptor gene in human erythroleukemia cells. Biochem. Pharmacol. 71 (2006) 1308-1323
    • (2006) Biochem. Pharmacol. , vol.71 , pp. 1308-1323
    • Coyle, A.T.1    Kinsella, B.T.2
  • 21
    • 59649116172 scopus 로고    scopus 로고
    • Regulation of the human thromboxane A2 receptor gene by Sp1, Egr1, NF-E2, GATA-1 and Ets-1 in megakaryocytes
    • Gannon A.M., and Kinsella B.T. Regulation of the human thromboxane A2 receptor gene by Sp1, Egr1, NF-E2, GATA-1 and Ets-1 in megakaryocytes. J. Lipid Res. 49 (2008) 2590-2604
    • (2008) J. Lipid Res. , vol.49 , pp. 2590-2604
    • Gannon, A.M.1    Kinsella, B.T.2
  • 22
    • 85080844443 scopus 로고    scopus 로고
    • The Wilms' tumor suppressor protein WT1 acts as a key transcriptional repressor of the human thromboxane A2 receptor gene in megakaryocytes
    • 10.111/j.1582-4934.2008
    • Gannon A.M., and Kinsella B.T. The Wilms' tumor suppressor protein WT1 acts as a key transcriptional repressor of the human thromboxane A2 receptor gene in megakaryocytes. J. Cell. Mol. Med. (2008) 10.111/j.1582-4934.2008
    • (2008) J. Cell. Mol. Med.
    • Gannon, A.M.1    Kinsella, B.T.2
  • 24
    • 0021382037 scopus 로고
    • Expression of platelet membrane glycoproteins and alpha-granule proteins by a human erythroleukemia cell line (HEL)
    • Tabilio A., Rosa J.P., Testa U., Kieffer N., Nurden A.T., Del Canizo M.C., et al. Expression of platelet membrane glycoproteins and alpha-granule proteins by a human erythroleukemia cell line (HEL). EMBO J. 3 (1984) 453-459
    • (1984) EMBO J. , vol.3 , pp. 453-459
    • Tabilio, A.1    Rosa, J.P.2    Testa, U.3    Kieffer, N.4    Nurden, A.T.5    Del Canizo, M.C.6
  • 25
    • 0029829231 scopus 로고    scopus 로고
    • Novel role for Sp1 in phorbol ester enhancement of human platelet thromboxane receptor gene expression
    • D'Angelo D.D., Oliver B.G., Davis M.G., McCluskey T.S., and Dorn G.W. Novel role for Sp1 in phorbol ester enhancement of human platelet thromboxane receptor gene expression. J. Biol. Chem. 271 (1996) 19696-19704
    • (1996) J. Biol. Chem. , vol.271 , pp. 19696-19704
    • D'Angelo, D.D.1    Oliver, B.G.2    Davis, M.G.3    McCluskey, T.S.4    Dorn, G.W.5
  • 26
    • 0028799701 scopus 로고
    • Sequence and structural requirements for high-affinity DNA binding by the WT1 gene product
    • Nakagama H., Heinrich G., Pelletier J., and Housman D.E. Sequence and structural requirements for high-affinity DNA binding by the WT1 gene product. Mol. Cell. Biol. 15 (1995) 1489-1498
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1489-1498
    • Nakagama, H.1    Heinrich, G.2    Pelletier, J.3    Housman, D.E.4
  • 27
    • 0029865115 scopus 로고    scopus 로고
    • Transcriptional regulation of murine beta1,4-galactosyltransferase in somatic cells. Analysis of a gene that serves both a housekeeping and a mammary gland-specific function
    • Rajput B., Shaper N.L., and Shaper J.H. Transcriptional regulation of murine beta1,4-galactosyltransferase in somatic cells. Analysis of a gene that serves both a housekeeping and a mammary gland-specific function. J. Biol. Chem. 271 (1996) 5131-5142
    • (1996) J. Biol. Chem. , vol.271 , pp. 5131-5142
    • Rajput, B.1    Shaper, N.L.2    Shaper, J.H.3
  • 28
    • 0025037502 scopus 로고
    • GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase
    • Jackson S.P., MacDonald J.J., Lees-Miller S., and Tjian R. GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase. Cell 63 (1990) 155-165
    • (1990) Cell , vol.63 , pp. 155-165
    • Jackson, S.P.1    MacDonald, J.J.2    Lees-Miller, S.3    Tjian, R.4
  • 29
    • 0027931178 scopus 로고
    • Wilms' tumor gene, WT1, mRNA is down-regulated during induction of erythroid and megakaryocytic differentiation of K562 cells
    • Phelan S.A., Lindberg C., and Call K.M. Wilms' tumor gene, WT1, mRNA is down-regulated during induction of erythroid and megakaryocytic differentiation of K562 cells. Cell Growth Differ. 5 (1994) 677-686
    • (1994) Cell Growth Differ. , vol.5 , pp. 677-686
    • Phelan, S.A.1    Lindberg, C.2    Call, K.M.3
  • 31
    • 0028084337 scopus 로고
    • Ternary complex factors: growth factor regulated transcriptional activators
    • Treisman R. Ternary complex factors: growth factor regulated transcriptional activators. Curr. Opin. Genet. Dev. 4 (1994) 96-101
    • (1994) Curr. Opin. Genet. Dev. , vol.4 , pp. 96-101
    • Treisman, R.1
  • 32
    • 0027980492 scopus 로고
    • Transient activation of RAF-1, MEK, and ERK2 coincides kinetically with ternary complex factor phosphorylation and immediate-early gene promoter activity in vivo
    • Hipskind R.A., Baccarini M., and Nordheim A. Transient activation of RAF-1, MEK, and ERK2 coincides kinetically with ternary complex factor phosphorylation and immediate-early gene promoter activity in vivo. Mol. Cell. Biol. 14 (1994) 6219-6231
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 6219-6231
    • Hipskind, R.A.1    Baccarini, M.2    Nordheim, A.3
  • 33
    • 0242497936 scopus 로고    scopus 로고
    • Specific interaction of Egr1 and c/EBPbeta leads to the transcriptional activation of the human low density lipoprotein receptor gene
    • Zhang F., Lin M., Abidi P., Thiel G., and Liu J. Specific interaction of Egr1 and c/EBPbeta leads to the transcriptional activation of the human low density lipoprotein receptor gene. J. Biol. Chem. 278 (2003) 44246-44254
    • (2003) J. Biol. Chem. , vol.278 , pp. 44246-44254
    • Zhang, F.1    Lin, M.2    Abidi, P.3    Thiel, G.4    Liu, J.5
  • 34
    • 0028227357 scopus 로고
    • The phosphorylated forms of the transcription factor, Egr-1, bind to DNA more efficiently than non-phosphorylated
    • Huang R.P., and Adamson E.D. The phosphorylated forms of the transcription factor, Egr-1, bind to DNA more efficiently than non-phosphorylated. Biochem. Biophys. Res. Commun. 200 (1994) 1271-1276
    • (1994) Biochem. Biophys. Res. Commun. , vol.200 , pp. 1271-1276
    • Huang, R.P.1    Adamson, E.D.2
  • 35
    • 0033000998 scopus 로고    scopus 로고
    • Pathways of Egr-1-mediated gene transcription in vascular biology
    • Silverman E.S., and Collins T. Pathways of Egr-1-mediated gene transcription in vascular biology. Am. J. Pathol. 154 (1999) 665-670
    • (1999) Am. J. Pathol. , vol.154 , pp. 665-670
    • Silverman, E.S.1    Collins, T.2
  • 36
    • 0142215639 scopus 로고    scopus 로고
    • The Wilms' tumour suppressor protein, WT1, undergoes CRM1-independent nucleocytoplasmic shuttling
    • Vajjhala P.R., Macmillan E., Gonda T., and Little M. The Wilms' tumour suppressor protein, WT1, undergoes CRM1-independent nucleocytoplasmic shuttling. FEBS Lett. 554 (2003) 143-148
    • (2003) FEBS Lett. , vol.554 , pp. 143-148
    • Vajjhala, P.R.1    Macmillan, E.2    Gonda, T.3    Little, M.4
  • 37
    • 0029853390 scopus 로고    scopus 로고
    • Regulation of WT1 by phosphorylation: inhibition of DNA binding, alteration of transcriptional activity and cellular translocation
    • Ye Y., Raychaudhuri B., Gurney A., Campbell C.E., and Williams B.R. Regulation of WT1 by phosphorylation: inhibition of DNA binding, alteration of transcriptional activity and cellular translocation. EMBO J. 15 (1996) 5606-5615
    • (1996) EMBO J. , vol.15 , pp. 5606-5615
    • Ye, Y.1    Raychaudhuri, B.2    Gurney, A.3    Campbell, C.E.4    Williams, B.R.5
  • 38
    • 34250860039 scopus 로고    scopus 로고
    • The transcription factor Wilms tumor 1 regulates matrix metalloproteinase-9 through a nitric oxide-mediated pathway
    • Marcet-Palacios M., Ulanova M., Duta F., Puttagunta L., Munoz S., Gibbings D., et al. The transcription factor Wilms tumor 1 regulates matrix metalloproteinase-9 through a nitric oxide-mediated pathway. J. Immunol. 179 (2007) 256-265
    • (2007) J. Immunol. , vol.179 , pp. 256-265
    • Marcet-Palacios, M.1    Ulanova, M.2    Duta, F.3    Puttagunta, L.4    Munoz, S.5    Gibbings, D.6
  • 39
    • 0035920219 scopus 로고    scopus 로고
    • In vivo formation of a human beta-globin locus control region core element requires binding sites for multiple factors including GATA-1, NF-E2, erythroid Kruppel-like factor, and Sp1
    • Goodwin A.J., McInerney J.M., Glander M.A., Pomerantz O., and Lowrey C.H. In vivo formation of a human beta-globin locus control region core element requires binding sites for multiple factors including GATA-1, NF-E2, erythroid Kruppel-like factor, and Sp1. J. Biol. Chem. 276 (2001) 26883-26892
    • (2001) J. Biol. Chem. , vol.276 , pp. 26883-26892
    • Goodwin, A.J.1    McInerney, J.M.2    Glander, M.A.3    Pomerantz, O.4    Lowrey, C.H.5
  • 40
    • 0032545033 scopus 로고    scopus 로고
    • Serum responsive gene expression mediated by Sp1
    • Kumar A.P., and Butler A.P. Serum responsive gene expression mediated by Sp1. Biochem. Biophys. Res. Commun. 252 (1998) 517-523
    • (1998) Biochem. Biophys. Res. Commun. , vol.252 , pp. 517-523
    • Kumar, A.P.1    Butler, A.P.2
  • 41
    • 44649166455 scopus 로고    scopus 로고
    • PKC{alpha}-induced derepression of the human LH receptor gene transcription through ERK-mediated release of HDAC1/Sin3A corepressor complex from Sp1 sites
    • Liao M., Zhang Y., and Dufau M.L. PKC{alpha}-induced derepression of the human LH receptor gene transcription through ERK-mediated release of HDAC1/Sin3A corepressor complex from Sp1 sites. Mol. Endocrinol. 22 (2008) 1449-1463
    • (2008) Mol. Endocrinol. , vol.22 , pp. 1449-1463
    • Liao, M.1    Zhang, Y.2    Dufau, M.L.3
  • 42
    • 0027942751 scopus 로고
    • Transcription factor egr-1 is involved in phorbol 12-myristate 13-acetate-induced megakaryocytic differentiation of K562 cells
    • Cheng T., Wang Y., and Dai W. Transcription factor egr-1 is involved in phorbol 12-myristate 13-acetate-induced megakaryocytic differentiation of K562 cells. J. Biol. Chem. 269 (1994) 30848-30853
    • (1994) J. Biol. Chem. , vol.269 , pp. 30848-30853
    • Cheng, T.1    Wang, Y.2    Dai, W.3
  • 43
    • 33750995582 scopus 로고    scopus 로고
    • Early growth response transcription factor EGR-1 regulates Galphaq gene in megakaryocytic cells
    • Jalagadugula G., Dhanasekaran D.N., Kim S., Kunapuli S.P., and Rao A.K. Early growth response transcription factor EGR-1 regulates Galphaq gene in megakaryocytic cells. J. Thromb. Haemost. 4 (2006) 2678-2686
    • (2006) J. Thromb. Haemost. , vol.4 , pp. 2678-2686
    • Jalagadugula, G.1    Dhanasekaran, D.N.2    Kim, S.3    Kunapuli, S.P.4    Rao, A.K.5
  • 44
    • 55549143361 scopus 로고    scopus 로고
    • Phorbol 12-myristate 13-acetate (PMA) responsive sequence in Galphaq promoter during megakaryocytic differentiation. Regulation by EGR-1 and MAP kinase pathway
    • Jalagadugula G., Dhanasekaran D.N., and Rao A.K. Phorbol 12-myristate 13-acetate (PMA) responsive sequence in Galphaq promoter during megakaryocytic differentiation. Regulation by EGR-1 and MAP kinase pathway. Thromb. Haemostasis 100 (2008) 821-828
    • (2008) Thromb. Haemostasis , vol.100 , pp. 821-828
    • Jalagadugula, G.1    Dhanasekaran, D.N.2    Rao, A.K.3
  • 45
    • 0030756508 scopus 로고    scopus 로고
    • Defective platelet activation in G alpha(q)-deficient mice
    • Offermanns S., Toombs C.F., Hu Y.H., and Simon M.I. Defective platelet activation in G alpha(q)-deficient mice. Nature 389 (1997) 183-186
    • (1997) Nature , vol.389 , pp. 183-186
    • Offermanns, S.1    Toombs, C.F.2    Hu, Y.H.3    Simon, M.I.4
  • 46
    • 0034060981 scopus 로고    scopus 로고
    • High-level expression of Egr-1 and Egr-1-inducible genes in mouse and human atherosclerosis
    • McCaffrey T.A., Fu C., Du B., Eksinar S., Kent K.C., Bush Jr. H., et al. High-level expression of Egr-1 and Egr-1-inducible genes in mouse and human atherosclerosis. J. Clin. Invest. 105 (2000) 653-662
    • (2000) J. Clin. Invest. , vol.105 , pp. 653-662
    • McCaffrey, T.A.1    Fu, C.2    Du, B.3    Eksinar, S.4    Kent, K.C.5    Bush Jr., H.6
  • 47
    • 0034597331 scopus 로고    scopus 로고
    • The human transcriptional repressor protein NAB1: expression and biological activity
    • Thiel G., Kaufmann K., Magin A., Lietz M., Bach K., and Cramer M. The human transcriptional repressor protein NAB1: expression and biological activity. Biochim. Biophys. Acta 1493 (2000) 289-301
    • (2000) Biochim. Biophys. Acta , vol.1493 , pp. 289-301
    • Thiel, G.1    Kaufmann, K.2    Magin, A.3    Lietz, M.4    Bach, K.5    Cramer, M.6
  • 48
    • 28244481494 scopus 로고    scopus 로고
    • Transcription factor specificity protein 1 (Sp1) is the main regulator of nerve growth factor-induced sphingosine kinase 1 gene expression of the rat pheochromocytoma cell line, PC12
    • Sobue S., Hagiwara K., Banno Y., Tamiya-Koizumi K., Suzuki M., Takagi A., et al. Transcription factor specificity protein 1 (Sp1) is the main regulator of nerve growth factor-induced sphingosine kinase 1 gene expression of the rat pheochromocytoma cell line, PC12. J. Neurochem. 95 (2005) 940-949
    • (2005) J. Neurochem. , vol.95 , pp. 940-949
    • Sobue, S.1    Hagiwara, K.2    Banno, Y.3    Tamiya-Koizumi, K.4    Suzuki, M.5    Takagi, A.6
  • 49
    • 45949096604 scopus 로고    scopus 로고
    • The Wilms' tumour suppressor WT1 is involved in endothelial cell proliferation and migration: expression in tumour vessels in vivo
    • Wagner N., Michiels J.F., Schedl A., and Wagner K.D. The Wilms' tumour suppressor WT1 is involved in endothelial cell proliferation and migration: expression in tumour vessels in vivo. Oncogene 27 (2008) 3662-3672
    • (2008) Oncogene , vol.27 , pp. 3662-3672
    • Wagner, N.1    Michiels, J.F.2    Schedl, A.3    Wagner, K.D.4
  • 50
    • 0036739302 scopus 로고    scopus 로고
    • Identification of Egr1 as the oncostatin M-induced transcription activator that binds to sterol-independent regulatory element of human LDL receptor promoter
    • Zhang F., Ahlborn T.E., Li C., Kraemer F.B., and Liu J. Identification of Egr1 as the oncostatin M-induced transcription activator that binds to sterol-independent regulatory element of human LDL receptor promoter. J. Lipid Res. 43 (2002) 1477-1485
    • (2002) J. Lipid Res. , vol.43 , pp. 1477-1485
    • Zhang, F.1    Ahlborn, T.E.2    Li, C.3    Kraemer, F.B.4    Liu, J.5
  • 51
    • 1242285630 scopus 로고    scopus 로고
    • The Wilms' tumour protein (WT1) shuttles between nucleus and cytoplasm and is present in functional polysomes
    • Niksic M., Slight J., Sanford J.R., Caceres J.F., and Hastie N.D. The Wilms' tumour protein (WT1) shuttles between nucleus and cytoplasm and is present in functional polysomes. Hum. Mol. Genet. 13 (2004) 463-471
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 463-471
    • Niksic, M.1    Slight, J.2    Sanford, J.R.3    Caceres, J.F.4    Hastie, N.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.