The transcription factor Wilms tumor 1 regulates matrix metalloproteinase-9 through a nitric oxide-mediated pathway

Journal of Immunology

Volumn 179, Issue 1, 2007, Pages 256-265

  Marcet Palacios, Marcelo ^a   Ulanova, Marina ^b   Duta, Florentina ^a   Puttagunta, Lakshmi ^d   Munoz, Samira ^a   Gibbings, Derrick ^a   Radomski, Marek ^c   Cameron, Lisa ^a   Mayers, Irvin ^a   Befus, A Dean ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b LAKEHEAD UNIVERSITY   (Canada)

^c TRINITY COLLEGE DUBLIN   (Ireland)

^d UNIVERSITY OF ALBERTA HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GELATINASE B; LIPOPOLYSACCHARIDE; N [3 (AMINOMETHYL)BENZYL]ACETAMIDINE; NITRIC OXIDE; PHORBOL 13 ACETATE 12 MYRISTATE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR; WT1 PROTEIN;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA FLANKING REGION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; TRANSCRIPTION REGULATION; UPREGULATION;

EID: 34250860039     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.179.1.256     Document Type: Article

References (48)

1. Atkinson, J. J., and R. M. Senior. 2003. Matrix metalloproteinase-9 in lung remodeling. Am. J. Respir. Cell Mol. Biol. 28: 12-24.
2. Somerville, R. P., S. A. Oblander, and S. S. Apte. 2003. Matrix metalloproteinases: old dogs with new tricks. Genome Biol. 4: 216.
3. Han, Z., Junxu, and N. Zhong. 2003. Expression of matrix metalloproteinases MMP-9 within the airways in asthma. Respir. Med. 97: 563-567.
4. Mautino, G., N. Oliver, P. Chanez, J. Bousquet, and F. Capony. 1997. Increased release of matrix metalloproteinase-9 in bronchoalveolar lavage fluid and by alveolar macrophages of asthmatics. Am. J. Respir. Cell Mol. Biol. 17: 583-591.
5. Lee, Y. C., H. B. Lee, Y. K. Rhee, and C. H. Song. 2001. The involvement of matrix metalloproteinase-9 in airway inflammation of patients with acute asthma. Clin. Exp. Allergy 31: 1623-1630.
6. Kelly, E. A., W. W. Busse, and N. N. Jarjour. 2000. Increased matrix metalloproteinase-9 in the airway after allergen challenge. Am. J. Respir. Crit. Care Med. 162: 1157-1161.
7. McMillan, S. J., J. Kearley, J. D. Campbell, X. W. Zhu, K. Y. Larbi, J. M. Shipley, R. M. Senior, S. Nourshargh, and C. M. Lloyd. 2004. Matrix metalloproteinase-9 deficiency results in enhanced allergen-induced airway inflammation. J. Immunol. 172: 2586-2594.
8. d'Ortho, M. P., C. Clerici, P. M. Yao, C. Delacourt, C. Delclaux, M. L. Franco-Montoya, A. Harf, and C. Lafuma. 1997. Alveolar epithelial cells in vitro produce gelatinases and tissue inhibitor of matrix metalloproteinase-2. Am. J. Physiol. 273: L663-675.
9. Hozumi, A., Y. Nishimura, T. Nishiuma, Y. Kotani, and M. Yokoyama. 2001. Induction of MMP-9 in normal human bronchial epithelial cells by TNF-α via NF-κB-mediated pathway. Am. J. Physiol. 281: L1444-L1452.
10. Ichiyasu, H., J. M. McCormack, K. M. McCarthy, D. Dombkowski, F. I. Preffer, and E. E. Schneeberger. 2004. Matrix metalloproteinase-9-delicient dendritic cells have impaired migration through tracheal epithelial tight junctions. Am. J. Respir. Cell Mol. Biol. 30: 761-770.
11. Vermaelen, K. Y., D. Cataldo, K. Tournoy, T. Maes, A. Dhulst, R. Louis, J. M. Foidart, A. Noel, and R. Pauwels. 2003. Matrix metalloproteinase-9- mediated dendritic cell recruitment into the airways is a critical step in a mouse model of asthma. J. Immunol. 171: 1016-1022.
12. Cataldo, D. D., K. G. Tournoy, K. Vermaelen, C. Munaut, J. M. Foidart, R. Louis, A. Noel, and R. A. Pauwels. 2002. Matrix metalloproteinase-9 deficiency impairs cellular infiltration and bronchial hyperresponsiveness during allergen-induced airway inflammation. Am. J. Pathol. 161: 491-498.
13. Naoum, J. J., K. J. Woodside, S. Zhang, P. G. Rychahou, and G. C. Hunter. 2005. Effects of rapamycin on the arterial inflammatory response in atherosclerotic plaques in Apo-E knockout mice. Transplant. Proc. 37: 1880-1884.
14. Egi, K., N. E. Conrad, J. Kwan, C. Schulze, R. Schulz, and S. M. Wildhirt. 2004. Inhibition of inducible nitric oxide synthase and superoxide production reduces matrix metalloproteinase-9 activity and restores coronary vasomotor function in rat cardiac allografts. Eur. J. Cardiothorac. Surg. 26: 262-269.
15. Gu, Z., M. Kaul, B. Yan, S. J. Kridel, J. Cui, A. Strongin, J. W. Smith, R. C. Liddington, and S. A. Lipton. 2002. S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death. Science 297: 1186-1190.
16. Mayers, I., T. Hurst, A. Radomski, D. Johnson, S. Fricker, G. Bridger, B. Cameron, M. Darkes, and M. W. Radomski. 2003. Increased matrix metalloproteinase activity after canine cardiopulmonary bypass is suppressed by a nitric oxide scavenger. J. Thorac. Cardiovasc. Surg. 125: 661-668.
17. Mayers, I., T. Hurst, L. Puttagunta, A. Radomski, T. Mycyk, G. Sawicki, D. Johnson, and M. W. Radomski. 2001. Cardiac surgery increases the activity of matrix metalloproteinases and nitric oxide synthase in human hearts. J. Thorac. Cardiovasc. Surg. 122: 746-752.
18. Marcet-Palacios, M., K. Graham, C. Cass, A. D. Befus, I. Mayers, and M. W. Radomski. 2003. Nitric oxide and cyclic GMP increase the expression of matrix metalloproteinase-9 in vascular smooth muscle. J. Pharmacol. Exp. Ther. 307: 429-436.
19. Takimoto, E., H. C. Champion, M. Li, S. Ren, E. R. Rodriguez, B. Tavazzi, G. Lazzarino, N. Paolocci, K. L. Gabrielson, Y. Wang, and D. A. Kass. 2005. Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load. J. Clin. Invest. 115: 1221-1231.
20. Chen, Y., S. Hozawa, S. Sawamura, S. Sato, N. Fukuyama, C. Tsuji, T. Mine, Y. Okada, R. Tanino, Y. Ogushi, and H. Nakazawa. 2005. Deficiency of inducible nitric oxide synthase exacerbates hepatic fibrosis in mice fed high-fat diet. Biochem. Biophys. Res. Commun. 326: 45-51.
21. Joos, L., J. Q. He, M. B. Shepherdson, J. E. Connett, N. R. Anthonisen, P. D. Pare, and A. J. Sandford. 2002. The role of matrix metalloproteinase polymorphisms in the rate of decline in lung function. Hum. Mol. Genet. 11: 569-576.
22. Shimajiri, S., N. Arima, A. Tanimoto, Y. Murata, T. Hamada, K. Y. Wang, and Y. Sasaguri. 1999. Shortened microsatellite d(CA)21 sequence down-regulates promoter activity of matrix metalloproteinase 9 gene. FEBS Lett. 455: 70-74.
23. Mundlos, S., J. Pelletier, A. Darveau, M. Bachmann, A. Winterpacht, and B. Zabel. 1993. Nuclear localization of the protein encoded by the Wilms' tumor gene WT1 in embryonic and adult tissues. Development 119: 1329-1341.
24. Silberstein, G. B., K. Van Horn, P. Strickland, C. T. Roberts, Jr., and C. W. Daniel. 1997. Altered expression of the WT1 Wilms tumor suppressor gene in human breast cancer. Proc. Natl. Acad. Sci. USA 94: 8132-8137.
25. Lee, S. B., and D. A. Haber. 2001. Wilms tumor and the WT1 gene. Exp. Cell Res. 264: 74-99.
26. Sakamoto, Y., M. Yoshida, K. Semba, and T. Hunter. 1997. Inhibition of the DNA-binding and transcriptional repression activity of the Wilms' tumor gene product, WT1, by cAMP-dependent protein kinase-mediated phosphorylation of Ser-365 and Ser-393 in the zinc finger domain. Oncogene 15: 2001-2012.
27. Li, Z., J. Ajdic, M. Eigenthaler, and X. Du. 2003. A predominant role for cAMP-dependent protein kinase in the cGMP-induced phosphorylation of vasodilator-stimulated phosphoprotein and platelet inhibition in humans. Blood 101: 4423-4429.
28. Forte, L. R., P. K. Thome, S. L. Eber, W. J. Krause, R. H. Freeman, S. H. Francis, and J. D. Corbin. 1992. Stimulation of intestinal Cl- transport by heat-stable enterotoxin: activation of cAMP-dependent protein kinase by cGMP. Am. J. Physiol. 263: C607-C615.
29. 2+ channels by cyclic nucleotide cross activation of opposing protein kinases in rabbit portal vein. Circ. Res. 82: 557-565.
30. Drummond, I. A., S. L. Madden, P. Rohwer-Nutter, G. I. Bell, V. P. Sukhatme, and F. J. Rauscher, 3rd. 1992. Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1. Science 257: 674-678.
31. Madden, S. L., D. M. Cook, J. F. Morris, A. Gashler, V. P. Sukhatme, and F. J. Rauscher, III. 1991. Transcriptional repression mediated by the WT1 Wilms tumor gene product. Science 253: 1550-1553.
32. Wang, Z. Y., S. L. Madden, T. F. Deuel, and F. J. Rauscher, 3rd. 1992. The Wilms' tumor gene product, WT1, represses transcription of the platelet-derived growth factor A-chain gene. J. Biol. Chem. 267: 21999-22002.
33. Gilchrist, M., S. D. McCauley, and A. D. Befus. 2004. Expression, localization, and regulation of NOS in human mast cell lines: effects on leukotriene production. Blood 104: 462-469.
34. Bickmore, W. A., K. Oghene, M. H. Little, A. Seawright, V. van Heyningen, and N. D. Hastie. 1992. Modulation of DNA binding specificity by alternative splicing of the Wilms tumor wt1 gene transcript. Science 257: 235-237.
35. Mohamed, A. J., L. Vargas, B. F. Nore, C. M. Backesjo, B. Christensson, and C. I. Smith. 2000. Nucleocytoplasmic shuttling of Bruton's tyrosine kinase. J. Biol. Chem. 275: 40614-40619.
36. 1-integrin signaling and inflammatory responses in airway epithelial cells. Am. J. Physiol. 288: L497-L507.
37. Luecke, H. F., and K. R. Yamamoto. 2005. The glucocorticoid receptor blocks P-TEFb recruitment by NFκB to effect promoter-specific transcriptional repression. Genes Dev. 19: 1116-1127.
38. Boffelli, D., C. V. Weer, L. Weng, K. D. Lewis, M. I. Shoukry, L. Pachter, D. N. Keys, and E. M. Rubin. 2004. Intraspecies sequence comparisons for annotating genomes. Genome Res. 14: 2406-2411.
39. Scholz, H., and K. M. Kirschner. 2005. A role for the Wilms' tumor protein WT1 in organ development. Physiology 20: 54-59.
40. Rundlof, A. K., M. Carlsten, and E. S. Arner. 2001. The core promoter of human thioredoxin reductase 1: cloning, transcriptional activity, and Oct-1, Sp1, and Sp3 binding reveal a housekeeping-type promoter for the AU-rich element-regulated gene. J. Biol. Chem. 276: 30542-30551.
41. Choi, J. H., K. C. Choi, N. Auersperg, and P. C. Leung. 2006. Gonadotropins activate proteolysis and increase invasion through protein kinase A and phosphatidylinositol 3-kinase pathways in human epithelial ovarian cancer cells. Cancer Res. 66: 3912-3920.
42. Ye, Y., B. Raychaudhuri, A. Gurney, C. E. Campbell, and B. R. Williams. 1996. Regulation of WT1 by phosphorylation: inhibition of DNA binding, alteration of transcriptional activity and cellular translocation. EMBO J. 15: 5606-5615.
43. Wang, Z. Y., Q. Q. Qiu, J. Huang, M. Gurrieri, and T. F. Deuel. 1995. Products of alternatively spliced transcripts of the Wilms' tumor suppressor gene, wt1, have altered DNA binding specificity and regulate transcription in different ways. Oncogene 10: 415-422.
44. Himelstein, B. P., E. J. Lee, H. Sato, M. Seiki, and R. J. Muschel. 1998. Tumor cell contact mediated transcriptional activation of the fibroblast matrix metalloproteinase-9 gene: involvement of multiple transcription factors including Ets and an alternating purine-pyrimidine repeat. Clin. Exp. Metastasis 16: 169-177.
45. Wu, T., T. Ikezono, C. W. Angus, and J. H. Shelhamer. 1994. Characterization of the promoter for the human 85 kDa cytosolic phospholipase A2 gene. Nucleic Acids Res. 22: 5093-5098.
46. Yan, C., H. Wang, B. Aggarwal, and D. D. Boyd. 2004. A novel homologous recombination system to study 92 kDa type IV collagenase transcription demonstrates that the NF-κB motif drives the transition from a repressed to an activated state of gene expression. FASEB J. 18: 540-541.
47. Bradbury, N. A. 2000. Protein kinase-A-mediated secretion of mucin from human colonic epithelial cells. J. Cell Physiol. 185: 408-415.
48. Van Seuningen, I., P. Pigny, M. Perrais, N. Porchet, and J. P. Aubert. 2001. Transcriptional regulation of the 11p15 mucin genes: towards new biological tools in human therapy, in inflammatory diseases and cancer? Front Biosci. 6: D1216-D1234.