Chlorzoxazone hydroxylation in microsomes and hepatocytes from cytochrome P450 oxidoreductase-null mice

Journal of Biochemical and Molecular Toxicology

Volumn 23, Issue 5, 2009, Pages 357-363

  Li, Li ^a   Porter, Todd D ^a  

^a University of Kentucky   (United States)

Author keywords

Chlorzoxazone; Cytochrome b5; Cytochrome P450 2E1; Cytochrome P450 oxidoreductase; Hepatocytes

Indexed keywords

CHLORZOXAZONE; CYTOCHROME B5; CYTOCHROME P450; CYTOCHROME P450 2E1; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRON TRANSPORT; ENZYME ACTIVITY; HYDROXYLATION; LIVER CELL; LIVER MICROSOME; MOUSE; NONHUMAN; QUANTITATIVE ANALYSIS;

ANIMALS; CHLORZOXAZONE; CYTOCHROME P-450 CYP2E1; CYTOCHROMES B5; DOSE-RESPONSE RELATIONSHIP, DRUG; HEPATOCYTES; HYDROXYLATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSOMES, LIVER; NADP; NADPH-FERRIHEMOPROTEIN REDUCTASE; TEMPERATURE; TIME FACTORS; TRANSGENES;

MUS;

EID: 70350176618     PISSN: 10956670     EISSN: 10990461     Source Type: Journal    
DOI: 10.1002/jbt.20299     Document Type: Article

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