Crystal structure of Manduca sexta prophenoloxidase provides insights into the mechanism of type 3 copper enzymes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 40, 2009, Pages 17002-17006

  Li, Yongchao ^a   Wang, Yang ^a   Jiang, Haobo ^a   Deng, Junpeng ^a  

^a OKLAHOMA STATE UNIVERSITY   (United States)

Author keywords

Hemocyanin; Innate immune; Melanization; Tyrosinase; Zymogen activation

Indexed keywords

ARGININE DERIVATIVE; COPPER DERIVATIVE; COPPER ION; GLUTAMIC ACID DERIVATIVE; HETERODIMER; HISTIDINE DERIVATIVE; INSECT PROTEIN; MONOPHENOL MONOOXYGENASE; OXYGENASE; POLYPEPTIDE; PROPHENOL OXIDASE; PROPHENOLOXIDASE 1; PROPHENOLOXIDASE 2; TYPE 3 COPPER PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ELECTRICITY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SUBUNIT; INTROSPECTION; MANDUCA SEXTA; MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN FAMILY; PROTON TRANSPORT;

ANIMALS; CATALYTIC DOMAIN; CATECHOL OXIDASE; COPPER; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; ENZYME PRECURSORS; HISTIDINE; INSECT PROTEINS; MANDUCA; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; STATIC ELECTRICITY;

ARTHROPODA; HEXAPODA; MANDUCA SEXTA;

EID: 70350135449     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0906095106     Document Type: Article

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