Discovery and validation of colonic tumor-associated proteins via metabolic labeling and stable isotopic dilution

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 40, 2009, Pages 17235-17240

  Huttlin, Edward L ^a,e   Chen, Xiaodi ^b   Barrett Wilt, Gregory A ^a   Hegeman, Adrian D ^c   Halberg, Richard B ^b,d   Harms, Amy C ^a   Newton, Michael A ^d   Dove, William F ^a,b   Sussman, Michael R ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

^d UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Colon cancer; Differential mass spectrometry; Min mouse; Proteomics; Transcriptomics

Indexed keywords

ISOTOPE; NITROGEN 15; TUMOR PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CELL LABELING; COLON TUMOR; CONTROLLED STUDY; GENE EXPRESSION; ISOTOPE DILUTION ASSAY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; QUANTITATIVE ANALYSIS; TRANSCRIPTOMICS;

ADENOMATOUS POLYPOSIS COLI; ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; CHROMATOGRAPHY, LIQUID; COLONIC NEOPLASMS; DIET; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION PROFILING; HUMANS; ISOTOPE LABELING; LINEAR MODELS; MICE; MICE, INBRED C57BL; MUTATION; NEOPLASM PROTEINS; NITROGEN ISOTOPES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEOMICS; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SPIRULINA;

ALGAE; MUS; RODENTIA;

EID: 70350133594     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0909282106     Document Type: Article

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