Circulating cytokines in pulmonary tuberculosis according to HIV status and dietary iron content

International Journal of Tuberculosis and Lung Disease

Volumn 13, Issue 10, 2009, Pages 1267-1273

  Gordeuk, Victor R ^a   Moyo, V M ^b   Nouraie, M ^a   Gangaidzo, I T ^c   Murphree, N L ^d   Gomo, Z A R ^c   Boelaert, J R ^e   Weiss, G ^f  

^a HOWARD UNIVERSITY   (United States)

^b MERRIMACK PHARMACEUTICALS   (United States)

^c UNIVERSITY OF ZIMBABWE   (Zimbabwe)

^d Nyadire Mission Hospital   (Zimbabwe)

^e General Hospital St Jan   (Belgium)

^f INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

HIV; Immune response; Iron status; Tuberculosis

Indexed keywords

ASPARTATE AMINOTRANSFERASE; CYTOKINE; ETHAMBUTOL; FERRITIN; INTERLEUKIN 12; INTERLEUKIN 6; IRON; ISONIAZID; NEOPTERIN; NITRATE; NITRIC OXIDE; RIFAMPICIN; STREPTOMYCIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CYTOKINE PRODUCTION; DIETARY INTAKE; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IRON INTAKE; LUNG TUBERCULOSIS; MALE; PRIORITY JOURNAL; SERODIAGNOSIS; TH1 CELL; TH2 CELL; TUBERCULOSIS; ZIMBABWE;

ADULT; ANTITUBERCULAR AGENTS; CYTOKINES; FEMALE; HIV SEROPOSITIVITY; HUMANS; IRON, DIETARY; MALE; MIDDLE AGED; NITRATES; NITRITES; RISK FACTORS; TH1 CELLS; TH2 CELLS; TUBERCULOSIS, PULMONARY; YOUNG ADULT; ZIMBABWE;

EID: 70350099068     PISSN: 10273719     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. de Jong R, Altare F, Haagen I A, et al. Severe mycobacterial and salmonella infections in interleukin-12 receptor-deficient patients. Science 1998; 280: 1435-1438. (Pubitemid 28264837)
2. Romagnani S. The Th1/Th2 paradigm. Immunol Today 1997; 18: 263-266.
3. Rook G A, Hernandez-Pando R, Dheda K, Teng Seah G. IL-4 in tuberculosis: implications for vaccine design. Trends Immunol 2004; 25: 483-488. (Pubitemid 39490255)
4. Verbon A, Juffermans N, Van Deventer S J, Speelman P, Van Deutekom H, Van Der Poll T. Serum concentrations of cytokines in patients with active tuberculosis (TB) and after treatment. Clin Exp Immunol 1999; 115: 110-113. (Pubitemid 29030371)
5. De Cock K M, Soro B, Coulibaly I M, Lucas S B. Tuberculosis and HIV infection in sub-Saharan Africa. JAMA 1992; 268: 1581-1587.
6. Gordeuk V R. Hereditary and nutritional iron overload. Baillieres Clin Haematol 1992; 5: 169-186.
7. Rockstroh J K, Kreuzer K A, Sauerbruch T, Spengler U. Protein levels of interleukin-12 p70 holomer, its p40 chain and interferon-gamma during advancing HIV infection. J Infect 1998; 37: 282-286. (Pubitemid 29017276)
8. Wirleitner B, Schroecksnadel K, Winkler C, Fuchs D. Neopterin in HIV-1 infection. Mol Immunol 2005; 42: 183-194.
9. Gordeuk V R, McLaren C E, MacPhail A P, Deichsel G, Bothwell T H. Associations of iron overload in Africa with hepatocellular carcinoma and tuberculosis: Strachan's 1929 thesis revisited. Blood 1996; 87: 3470-3476.
10. Moyo V M, Mandishona E, Hasstedt S J, et al. Evidence of genetic transmission in African iron overload. Blood 1998; 91: 1076-1082. (Pubitemid 28078313)
11. Gordeuk VR, Caleffi A, Corradini E, et al. Iron overload in Africans and African-Americans and a common mutation in the SCL40A1 (ferroportin 1) gene. Blood Cells Mol Dis 2003; 31: 299-304. (Pubitemid 37433868)
12. Weiss G. Iron and immunity: a double-edged sword. Eur J Clin Invest 2002; 32 (Suppl 1): S70-S78.
13. Olakanmi O, Schlesinger L S, Britigan B E. Hereditary hemochromatosis results in decreased iron acquisition and growth by Mycobacterium tuberculosis within human macrophages. J Leukoc Biol 2007; 81: 195-204. (Pubitemid 46021269)
14. Schaible U E, Kaufmann S H. Iron and microbial infection. Nat Rev Microbiol 2004; 2: 946-953.
15. Drakesmith H, Prentice A. Viral infection and iron metabolism. Nat Rev Microbiol 2008; 6: 541-552.
16. Boelaert J R, Vandecasteele S J, Appelberg R, Gordeuk V R. The effect of the host's iron status on tuberculosis. J Infect Dis 2007; 195: 1745-1753. (Pubitemid 46870246)
17. Gangaidzo I T, Moyo V M, Mvundura E, et al. Association of pulmonary tuberculosis with increased dietary iron. J Infect Dis 2001; 184: 936-939. (Pubitemid 32881103)
18. Moyo V M, Gangaidzo I T, Gomo Z A, et al. Traditional beer consumption and the iron status of spouse pairs from a rural community in Zimbabwe. Blood 1997; 89: 2159-2166.
19. Wapnick A A, Bothwell T H, Seftel H. The relationship between serum ion levels and ascorbic acid stores in siderotic Bantu. Br J Haematol 1970; 19: 271-276.
20. Mackenzie B, Garrick M D. Iron imports. II. Iron uptake at the apical membrane in the intestine. Am J Physiol Gastrointest Liver Physiol 2005; 289: G981-G986. (Pubitemid 41742230)
21. Jacobson M A, Liu L, Khayam-Bashi H, Deeks S G, Hecht F M, Kahn J. Absolute or total lymphocyte count as a marker for the CD4 T lymphocyte criterion for initiating antiretroviral therapy. AIDS 2003; 17: 917-919. (Pubitemid 36547666)
22. International Committee for Standardisation in Haematology (Iron Panel). Recommendations for the measurement of serum iron in human blood. Br J Haematol 1978; 38: 291-294.
23. International Committee for Standardisation in Haematology (Iron Panel). The measurement of toal and unsaturated iron binding capacity in serum. Br J Haematol 1978; 38: 281-290.
24. Prieto J, Barry M, Sherlock S. Serum ferritin in patients with iron overload and with acute and chronic liver diseases. Gastroenterology 1975; 68: 525-533.
25. Weiss G, Bogdan C, Hentze M W. Pathways for the regulation of macrophage iron metabolism by the anti-inflammatory cytokines IL-4 and IL-13. J Immunol 1997; 158: 420-425. (Pubitemid 127483884)
26. Nathan C, Shiloh M U. Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens. Proc Natl Acad Sci USA 2000; 97: 8841-8848. (Pubitemid 30626635)
27. Dlaska M, Weiss G. Central role of transcription factor NF-IL6 for cytokine and iron-mediated regulation of murine inducible nitric oxide synthase expression. J Immunol 1999; 162: 6171-6177. (Pubitemid 29314979)
28. Swaminathan S, Gong J, Zhang M, et al. Cytokine production in children with tuberculous infection and disease. Clin Infect Dis 1999; 28: 1290-1293. (Pubitemid 29272805)
29. Immanuel C, Rajeswari R, Rahman F, Kumaran P P, Chandrasekaran V, Swamy R. Serial evaluation of serum neopterin in HIV-seronegative patients treated for tuberculosis. Int J Tuberc Lung Dis 2001; 5: 185-190.
30. Ma X, Montaner L J. Proinflammatory response and IL-12 expression in HIV-1 infection. J Leukoc Biol 2000; 68: 383-390.
31. Torre D, Ferrario G, Speranza F, Martegani R, Zeroli C. Increased levels of nitrite in the sera of children infected with human immunodeficiency virus type 1. Clin Infect Dis 1996; 22: 650-653. (Pubitemid 26286311)
32. Fuchs D, Hausen A, Reibnegger G, et al. Interferon-gamma concentrations are increased in sera from individuals infected with human immunodeficiency virus type 1. J Acquir Immune Defic Syndr 1989; 2: 158-162. (Pubitemid 19127092)
33. Huber C, Batchelor J R, Fuchs D, et al. Immune response-associated production of neopterin. Release from macrophages primarily under control of interferon-gamma. J Exp Med 1984; 160: 310-316. (Pubitemid 14089799)
34. Oexle H, Kaser A, Most J, et al. Pathways for the regulation of interferon-gamma-inducible genes by iron in human monocytic cells. J Leukoc Biol 2003; 74: 287-294. (Pubitemid 38040426)
35. Mencacci A, Cenci E, Boelaert J R, et al. Iron overload alters innate and T helper cell responses to Candida albicans in mice. J Infect Dis 1997; 175: 1467-1476. (Pubitemid 27225052)
36. Clerici M, Butto S, Lukwiya M, et al. Immune activation in Africa is environmentally-driven and is associated with upregulation of CCR5. Italian-Ugandan AIDS Project. AIDS 2000; 14: 2083-2092. (Pubitemid 30792480)
37. Lawn S D, Butera S T, Folks T M. Contribution of immune activation to the pathogenesis and transmission of human immunodeficiency virus type 1 infection. Clin Microbiol Rev 2001; 14: 753-777. (Pubitemid 32979630)
38. Strachan A S. Haemosiderosis and haemochromatosis in South African natives with a comment on the etiology of haemochromatosis. M.D. thesis, University of Glascow, 1929.