Excited to death: Different ways to lose your neurones

Biogerontology

Volumn 3, Issue 1-2, 2002, Pages 51-56

  Dodd, Peter R ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Alcoholism; Alzheimer disease; Excitotoxicity; GABA; Glutamate; Human brain; Pathogenesis

Indexed keywords

4 AMINOBUTYRIC ACID; ALCOHOL; CELL SURFACE RECEPTOR; GLUTAMIC ACID; POSTSYNAPTIC RECEPTOR;

ALZHEIMER DISEASE; ARTICLE; BRAIN INJURY; CELL DEATH; CELL KILLING; CELL LOSS; CELL STIMULATION; CELL TRANSPORT; CONTROLLED STUDY; CYTOTOXICITY; DEGENERATIVE DISEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERSENSITIVITY; NERVE CELL; PATHOPHYSIOLOGY; PRESYNAPTIC NERVE; PRIORITY JOURNAL; STIMULATION; SYNAPTIC TRANSMISSION;

ANIMALS; CELL DEATH; EXCITATORY AMINO ACIDS; HUMANS; NEURONS;

EID: 0036203974     PISSN: 13895729     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1015255312948     Document Type: Article

References (61)

1. Alternative excitotoxic hypotheses
2. Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance
3. Heterogeneity of high affinity uptake of L-glutamate and L-aspartate in the mammalian central nervous system
4. Distinct, developmentally regulated brain mRNAs direct the synthesis of neurotransmitter transporters
5. Biochemistry and basic mechanisms in epilepsy
6. Convulsions and activation of epileptic foci induced by monosodium glutamate and related compounds
7. A receptor subtypes in human alcoholic brain
8. Cerebral GABA-ergic and glutamatergic function in hepatic encephalopathy
9. Glutamate and epilepsy
10. Excitotoxicity of NMDA and kainic acid is modulated by nigrostriatal dopaminergic fibres
11. Excitatory amino acid receptors in the vertebrate central nervous system
12. The glutamate transporter EAAT4 in rat cerebellar Purkinje cells: A glutamate-gated chloride channel concentrated near the synapse in parts of the dendritic membrane facing astroglia
13. A comparison of methodologies for the study of functional transmitter neurochemistry in human brain
14. Amino acid neurotransmitter receptor changes in cerebral cortex in alcoholism: Effect of cirrhosis of the liver
15. Excitotoxic mechanisms in the pathogenesis of dementia
16. Receptor binding sites and uptake activities mediating GABA neurotransmission in chronic alcoholics with Wernicke encephalopathy
17. Cell death mediated by amino acid transmitter receptors in human alcoholic brain damage: Conflicts in the evidence
18. Glutamate-mediated transmission, alcohol, and alcoholism
19. A receptors in rat brain
20. Amyotrophic lateral sclerosis is a multifactorial disease
21. 3H]aspartate from cerebral cortical synaptosomes
22. A receptor following exposure to diazepam
23. Region-specific loss of glutamate innervation in Alzheimer's disease
24. Brain glutamate transporter proteins form homomultimers
25. Distribution of GABA-containing neurons in human frontal cortex: A quantitative immunocytochemical study
26. Alzheimer's disease: Cell-specific pathology isolates the hippocampal formation
27. NMDA receptor NR1 subunit mRNA expression in Alzheimer's disease
28. Diagnosis of Alzheimer's disease
29. The cerebral cortex is damaged in chronic alcoholics
30. Activities of neuronal and astrocytic marker enzymes in autopsied brain tissue from patients with hepatic encephalopathy
31. A receptor in human alcoholic brain
32. A receptor in brain from human cirrhotic and non-cirrhotic alcoholics
33. A receptor α subunit proteins in human chronic alcoholics
34. A novel inhibitor of glutamate release reduces excitotoxic injury in vitro
35. β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
36. Alternative splicing of the glutamate transporter EAAT2 (GLT-1)
37. Roles of metabotropic glutamate receptors in brain plasticity and pathology
38. The modulatory effect of spermine on the glutamate-NMDA receptor is regionally variable in normal human adult cerebral cortex
39. Concurrent down-regulation of a glutamate transporter and receptor in glaucoma
40. Stucture-activity relationships of conantokins at the human glutamate-NMDA receptor
41. Release of excitatory amino acids from cultured hippocampal astrocytes induced by a hypoxic-hypoglycemic stimulation
42. Glutamate transport and storage in synaptic vesicles
43. Kainic acid differentially affects the synaptosomal release of endogenous and exogenous amino acidic neurotransmitters
44. A-benzodiazepine receptors produced in transfected cells
45. Glutamate and the pathophysiology of hypoxic-ischemic brain damage
46. Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis
47. Localization of neuronal and glial glutamate transporters
48. Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis
49. In vitro and in vivo pharmacology of trans- and cis-(+-)-1-amino-1,3-cyclopentanedicarboxylic acid: Dissociation of metabotropic and ionotropic excitatory amino acid receptor effects
50. Variant forms of neuronal glutamate transporter sites in Alzheimer's disease cerebral cortex
51. The identification and characterization of excitotoxic nerve-endings in Alzheimer disease
52. Aberrant expression of glutamate transporter EAATI in Alzheimer's disease
53. A receptor heterogeneity: An integrated molecular approach
54. The metabotropic glutamate receptor (MGR): Pharmacology and subcellular location
55. Excitatory amino acids in health and disease
56. Lamotrigine in Rett syndrome
57. Cerebral blood flow and ischemia-induced neurotransmitter release in the striatum of aged spontaneously hypertensive rats
58. α-Amino-3-hydroxy-5-methyl-4-isoxazolepro pionate (AMPA) receptors mediate excitotoxicity in the oligodendroglial lineage
59. Excitatory amino acid-induced toxicity in chick retina: Amino acid release, histology, and effects of chloride channel blockers
60. Excitotoxicity at both NMDA and non-NMDA glutamate receptors is antagonized by aurintricarboxylic acid: Evidence for differing mechanisms of action