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Volumn 27, Issue 4, 2009, Pages 1063-1074

Sudden Unexpected Death in Epilepsy (SUDEP): Update and Reflections

Author keywords

AEDs; Definitions; Epilepsy; Mortemus; SUDEP; Supervision

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; LAMOTRIGINE; VALPROIC ACID;

EID: 70350070741     PISSN: 07338619     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ncl.2009.08.003     Document Type: Review
Times cited : (96)

References (50)
  • 1
    • 53649103661 scopus 로고    scopus 로고
    • Sudden unexpected death in epilepsy: current knowledge and future directions
    • Tomson T., Nashef L., and Ryvlin P. Sudden unexpected death in epilepsy: current knowledge and future directions. Lancet Neurol 7 11 (2008) 1021-1031
    • (2008) Lancet Neurol , vol.7 , Issue.11 , pp. 1021-1031
    • Tomson, T.1    Nashef, L.2    Ryvlin, P.3
  • 2
    • 70350066410 scopus 로고    scopus 로고
    • Sudden unexpected death in epilepsy
    • The epilepsies 3. Shorvon S., and Pedley T. (Eds), Saunders Elsevier, Philadelphia
    • Rugg-Gunn F., and Nashef L. Sudden unexpected death in epilepsy. The epilepsies 3. In: Shorvon S., and Pedley T. (Eds). Blue books of neurology (2009), Saunders Elsevier, Philadelphia 211-240
    • (2009) Blue books of neurology , pp. 211-240
    • Rugg-Gunn, F.1    Nashef, L.2
  • 3
    • 33644778810 scopus 로고    scopus 로고
    • Sudden unexpected death in epilepsy: a review of incidence and risk factors
    • Tomson T., Walczak T., Sillanpaa M., et al. Sudden unexpected death in epilepsy: a review of incidence and risk factors. Epilepsia 46 Suppl 11 (2005) 54-61
    • (2005) Epilepsia , vol.46 , Issue.SUPPL. 11 , pp. 54-61
    • Tomson, T.1    Walczak, T.2    Sillanpaa, M.3
  • 4
    • 17644390562 scopus 로고    scopus 로고
    • Sudden unexpected death in people with epilepsy: a pediatric perspective
    • Camfield P., and Camfield C. Sudden unexpected death in people with epilepsy: a pediatric perspective. Semin Pediatr Neurol 12 1 (2005) 10-14
    • (2005) Semin Pediatr Neurol , vol.12 , Issue.1 , pp. 10-14
    • Camfield, P.1    Camfield, C.2
  • 5
    • 2342600567 scopus 로고    scopus 로고
    • Cardiorespiratory findings in sudden unexplained/unexpected death in epilepsy (SUDEP)
    • Stöllberger C., and Finsterer J. Cardiorespiratory findings in sudden unexplained/unexpected death in epilepsy (SUDEP). Epilepsy Res 59 1 (2004) 51-60
    • (2004) Epilepsy Res , vol.59 , Issue.1 , pp. 51-60
    • Stöllberger, C.1    Finsterer, J.2
  • 6
    • 59749092844 scopus 로고    scopus 로고
    • A review of sudden unexpected death in epilepsy: prediction of patients at risk
    • Hughes J.R. A review of sudden unexpected death in epilepsy: prediction of patients at risk. Epilepsy Behav 14 2 (2009) 280-287
    • (2009) Epilepsy Behav , vol.14 , Issue.2 , pp. 280-287
    • Hughes, J.R.1
  • 7
    • 0031771841 scopus 로고    scopus 로고
    • Population-based study of the incidence of sudden unexplained death in epilepsy
    • Ficker D.M., So E.L., Shen W.K., et al. Population-based study of the incidence of sudden unexplained death in epilepsy. Neurology 51 5 (1998) 1270-1274
    • (1998) Neurology , vol.51 , Issue.5 , pp. 1270-1274
    • Ficker, D.M.1    So, E.L.2    Shen, W.K.3
  • 8
    • 33846821568 scopus 로고    scopus 로고
    • SUDEP in the Netherlands: a retrospective study in a tertiary referral center
    • Vlooswijk M.C., Majoie H.J., De Krom M.C., et al. SUDEP in the Netherlands: a retrospective study in a tertiary referral center. Seizure 16 2 (2007) 153-159
    • (2007) Seizure , vol.16 , Issue.2 , pp. 153-159
    • Vlooswijk, M.C.1    Majoie, H.J.2    De Krom, M.C.3
  • 9
    • 16844378420 scopus 로고    scopus 로고
    • Case-control study of SUDEP
    • Langan Y., Nashef L., and Sander J.W. Case-control study of SUDEP. Neurology 64 7 (2005) 1131-1133
    • (2005) Neurology , vol.64 , Issue.7 , pp. 1131-1133
    • Langan, Y.1    Nashef, L.2    Sander, J.W.3
  • 10
    • 0141828922 scopus 로고    scopus 로고
    • Risk factors for sudden unexpected death in epilepsy: a controlled prospective study based on coroners cases
    • Opeskin K., and Berkovic S.F. Risk factors for sudden unexpected death in epilepsy: a controlled prospective study based on coroners cases. Seizure 12 7 (2003) 456-464
    • (2003) Seizure , vol.12 , Issue.7 , pp. 456-464
    • Opeskin, K.1    Berkovic, S.F.2
  • 11
    • 0035001354 scopus 로고    scopus 로고
    • Antiepileptic drug therapy and its management in sudden unexpected death in epilepsy: a case-control study
    • Nilsson L., Bergman U., Diwan V., et al. Antiepileptic drug therapy and its management in sudden unexpected death in epilepsy: a case-control study. Epilepsia 42 5 (2001) 667-673
    • (2001) Epilepsia , vol.42 , Issue.5 , pp. 667-673
    • Nilsson, L.1    Bergman, U.2    Diwan, V.3
  • 12
    • 0035957118 scopus 로고    scopus 로고
    • Incidence and risk factors in sudden unexpected death in epilepsy: a prospective cohort study
    • Walczak T.S., Leppik I.E., D'Amelio M., et al. Incidence and risk factors in sudden unexpected death in epilepsy: a prospective cohort study. Neurology 56 4 (2001) 519-525
    • (2001) Neurology , vol.56 , Issue.4 , pp. 519-525
    • Walczak, T.S.1    Leppik, I.E.2    D'Amelio, M.3
  • 13
    • 0034176058 scopus 로고    scopus 로고
    • Sudden unexpected death in epilepsy (SUDEP): risk factors and case control studies
    • [Review]
    • Langan Y. Sudden unexpected death in epilepsy (SUDEP): risk factors and case control studies. Seizure 9 3 (2000) 179-183 [Review]
    • (2000) Seizure , vol.9 , Issue.3 , pp. 179-183
    • Langan, Y.1
  • 14
    • 0032762997 scopus 로고    scopus 로고
    • Comparison of antiepileptic drug levels in sudden unexpected deaths in epilepsy with deaths from other causes
    • Opeskin K., Burke M.P., Cordner S.M., et al. Comparison of antiepileptic drug levels in sudden unexpected deaths in epilepsy with deaths from other causes. Epilepsia 40 12 (1999) 1795-1798
    • (1999) Epilepsia , vol.40 , Issue.12 , pp. 1795-1798
    • Opeskin, K.1    Burke, M.P.2    Cordner, S.M.3
  • 15
    • 0032854608 scopus 로고    scopus 로고
    • Sudden unexpected death in epilepsy (SUDEP): a clinical perspective and a search for risk factors
    • Kloster R., and Engelskjøn T. Sudden unexpected death in epilepsy (SUDEP): a clinical perspective and a search for risk factors. J Neurol Neurosurg Psychiatr 67 4 (1999) 439-444
    • (1999) J Neurol Neurosurg Psychiatr , vol.67 , Issue.4 , pp. 439-444
    • Kloster, R.1    Engelskjøn, T.2
  • 16
    • 0033550997 scopus 로고    scopus 로고
    • Risk factors for sudden unexpected death in epilepsy: a case-control study
    • Nilsson L., Farahmand B.Y., Persson P.G., et al. Risk factors for sudden unexpected death in epilepsy: a case-control study. Lancet 353 9156 (1999) 888-893
    • (1999) Lancet , vol.353 , Issue.9156 , pp. 888-893
    • Nilsson, L.1    Farahmand, B.Y.2    Persson, P.G.3
  • 17
    • 0031947282 scopus 로고    scopus 로고
    • Circumstances of death in sudden death in epilepsy: interviews of bereaved relatives
    • Nashef L., Garner S., Sander J.W., et al. Circumstances of death in sudden death in epilepsy: interviews of bereaved relatives. J Neurol Neurosurg Psychiatr 64 3 (1998) 349-352
    • (1998) J Neurol Neurosurg Psychiatr , vol.64 , Issue.3 , pp. 349-352
    • Nashef, L.1    Garner, S.2    Sander, J.W.3
  • 18
    • 0042736049 scopus 로고    scopus 로고
    • Tongue bite injuries-a diagnostic criterium for death in epileptic seizure?
    • Ulrich J., and Maxeiner H. Tongue bite injuries-a diagnostic criterium for death in epileptic seizure?. Arch Kriminol 212 1-2 (2003) 19-29
    • (2003) Arch Kriminol , vol.212 , Issue.1-2 , pp. 19-29
    • Ulrich, J.1    Maxeiner, H.2
  • 19
    • 0031469059 scopus 로고    scopus 로고
    • Sudden unexpected death in epilepsy: terminology and definitions
    • Nashef L. Sudden unexpected death in epilepsy: terminology and definitions. Epilepsia 38 (1997) S6-S8
    • (1997) Epilepsia , vol.38
    • Nashef, L.1
  • 21
    • 0032885518 scopus 로고    scopus 로고
    • SUDEP: overview of definitions and review of incidence data
    • Annegers J.F., and Coan S.P. SUDEP: overview of definitions and review of incidence data. Seizure 8 6 (1999) 347-352
    • (1999) Seizure , vol.8 , Issue.6 , pp. 347-352
    • Annegers, J.F.1    Coan, S.P.2
  • 22
    • 0031467479 scopus 로고    scopus 로고
    • United States perspectives on definitions and classifications
    • Annegers J.F. United States perspectives on definitions and classifications. Epilepsia 38 s11 (1997) S9-12
    • (1997) Epilepsia , vol.38 , Issue.SUPPL.11
    • Annegers, J.F.1
  • 23
    • 57249099772 scopus 로고    scopus 로고
    • Nonadherence to antiepileptic drugs and increased mortality: findings from the RANSOM Study
    • Faught E., Duh M.S., Weiner J.R., et al. Nonadherence to antiepileptic drugs and increased mortality: findings from the RANSOM Study. Neurology 71 20 (2008) 1572-1578
    • (2008) Neurology , vol.71 , Issue.20 , pp. 1572-1578
    • Faught, E.1    Duh, M.S.2    Weiner, J.R.3
  • 24
    • 70350068310 scopus 로고    scopus 로고
    • Unit of Health Care Epidemiology, Oxford University and South East England Public Health Observatory. Epilepsy in England 1996 to 2004. A geographical profile of mortality. Available at: www.sepho.org.uk/. Accessed 2008.
    • Unit of Health Care Epidemiology, Oxford University and South East England Public Health Observatory. Epilepsy in England 1996 to 2004. A geographical profile of mortality. Available at: www.sepho.org.uk/. Accessed 2008.
  • 25
    • 33846885882 scopus 로고    scopus 로고
    • Lamotrigine in idiopathic epilepsy - increased risk of cardiac death?
    • Aurlien D., Leren T.P., Taubøll E., et al. Lamotrigine in idiopathic epilepsy - increased risk of cardiac death?. Acta Neurol Scand 115 3 (2007) 199-203
    • (2007) Acta Neurol Scand , vol.115 , Issue.3 , pp. 199-203
    • Aurlien, D.1    Leren, T.P.2    Taubøll, E.3
  • 26
    • 33947228816 scopus 로고    scopus 로고
    • (SANAD Study group). The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial
    • Marson A.G., Al-Kharusi A.M., Alwaidh M., et al. (SANAD Study group). The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial. Lancet 369 9566 (2007) 1016-1026
    • (2007) Lancet , vol.369 , Issue.9566 , pp. 1016-1026
    • Marson, A.G.1    Al-Kharusi, A.M.2    Alwaidh, M.3
  • 27
    • 70350068316 scopus 로고    scopus 로고
    • Genetics of sudden death in epilepsy
    • Lathers C., Schreider P.L., Bungo M.W., et al. (Eds), CRC Press, Boca Raton (FL)
    • Ghali N., and Nashef L. Genetics of sudden death in epilepsy. In: Lathers C., Schreider P.L., Bungo M.W., et al. (Eds). Sudden death in epilepsy. Forensic and clinical issues (2010), CRC Press, Boca Raton (FL)
    • (2010) Sudden death in epilepsy. Forensic and clinical issues
    • Ghali, N.1    Nashef, L.2
  • 28
    • 62149112931 scopus 로고    scopus 로고
    • Chromosome 15q11-13 duplication syndrome brain reveals epigenetic alterations in gene expression not predicted from copy number
    • Hogart A., Leung K.N., Wang N.J., et al. Chromosome 15q11-13 duplication syndrome brain reveals epigenetic alterations in gene expression not predicted from copy number. J Med Genet 46 2 (2009) 86-93
    • (2009) J Med Genet , vol.46 , Issue.2 , pp. 86-93
    • Hogart, A.1    Leung, K.N.2    Wang, N.J.3
  • 29
    • 70350064345 scopus 로고    scopus 로고
    • IDEAS IsoDicentric 15 Exchange, Advocacy & Support. Available at:
    • IDEAS IsoDicentric 15 Exchange, Advocacy & Support. Available at: (2009). http://www.idic15.org/dr_physicianadvisory.php
    • (2009)
  • 30
    • 38649138348 scopus 로고    scopus 로고
    • Two cases of sudden unexpected death in epilepsy in a GEFS+ family with an SCN1A mutation
    • Hindocha N., Nashef L., Elmslie F., et al. Two cases of sudden unexpected death in epilepsy in a GEFS+ family with an SCN1A mutation. Epilepsia 49 (2008) 360-365
    • (2008) Epilepsia , vol.49 , pp. 360-365
    • Hindocha, N.1    Nashef, L.2    Elmslie, F.3
  • 31
    • 45749090058 scopus 로고    scopus 로고
    • Sodium channel beta1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humans
    • Watanabe H., Koopmann T.T., Le Scouarnec S., et al. Sodium channel beta1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humans. J Clin Invest 118 (2008) 2260-2268
    • (2008) J Clin Invest , vol.118 , pp. 2260-2268
    • Watanabe, H.1    Koopmann, T.T.2    Le Scouarnec, S.3
  • 32
    • 60649106155 scopus 로고    scopus 로고
    • New SCN5A mutation in a SUDEP victim with idiopathic epilepsy
    • Aurlien D., Leren T.P., Taubøll E., et al. New SCN5A mutation in a SUDEP victim with idiopathic epilepsy. Seizure 18 2 (2009) 158-160
    • (2009) Seizure , vol.18 , Issue.2 , pp. 158-160
    • Aurlien, D.1    Leren, T.P.2    Taubøll, E.3
  • 33
    • 0034847363 scopus 로고    scopus 로고
    • Premature death in juvenile myoclonic epilepsy
    • Genton P., and Gelisse P. Premature death in juvenile myoclonic epilepsy. Acta Neurol Scand 104 (2001) 125-129
    • (2001) Acta Neurol Scand , vol.104 , pp. 125-129
    • Genton, P.1    Gelisse, P.2
  • 34
    • 34248592512 scopus 로고    scopus 로고
    • Risk factors in sudden death in epilepsy (SUDEP): the quest for mechanisms
    • Nashef L., Hindocha N., and Makoff A. Risk factors in sudden death in epilepsy (SUDEP): the quest for mechanisms. Epilepsia 48 (2007) 859-871
    • (2007) Epilepsia , vol.48 , pp. 859-871
    • Nashef, L.1    Hindocha, N.2    Makoff, A.3
  • 35
    • 17144450747 scopus 로고    scopus 로고
    • Prolongation of the QT interval and the sudden infant death syndrome
    • Schwartz P.J., Stramba-Badiale M., Segantini A., et al. Prolongation of the QT interval and the sudden infant death syndrome. N Engl J Med 338 (1998) 1709-1714
    • (1998) N Engl J Med , vol.338 , pp. 1709-1714
    • Schwartz, P.J.1    Stramba-Badiale, M.2    Segantini, A.3
  • 36
    • 35548938924 scopus 로고    scopus 로고
    • Sudden infant death syndrome
    • Moon R.Y., Horne R.S., and Hauck F.R. Sudden infant death syndrome. Lancet 370 9598 (2007) 1578-1587
    • (2007) Lancet , vol.370 , Issue.9598 , pp. 1578-1587
    • Moon, R.Y.1    Horne, R.S.2    Hauck, F.R.3
  • 37
    • 0346363231 scopus 로고    scopus 로고
    • Serotonin receptors: guardians of stable breathing
    • Richter D.W., Manzke T., Wilken B., et al. Serotonin receptors: guardians of stable breathing. Trends Mol Med 9 12 (2003) 542-548
    • (2003) Trends Mol Med , vol.9 , Issue.12 , pp. 542-548
    • Richter, D.W.1    Manzke, T.2    Wilken, B.3
  • 38
    • 42149163365 scopus 로고    scopus 로고
    • Simulated apnoeas induce serotonin-dependent respiratory long-term facilitation in rats
    • Mahamed S., and Mitchell G.S. Simulated apnoeas induce serotonin-dependent respiratory long-term facilitation in rats. J Physiol 586 8 (2008) 2171-2181
    • (2008) J Physiol , vol.586 , Issue.8 , pp. 2171-2181
    • Mahamed, S.1    Mitchell, G.S.2
  • 39
    • 0033001834 scopus 로고    scopus 로고
    • Effect of fluoxetine on maximal electroshock seizures in mice: acute vs chronic administration
    • Raju S.S., Noor A.R., Gurthu S., et al. Effect of fluoxetine on maximal electroshock seizures in mice: acute vs chronic administration. Pharm Res 39 6 (1999) 451-454
    • (1999) Pharm Res , vol.39 , Issue.6 , pp. 451-454
    • Raju, S.S.1    Noor, A.R.2    Gurthu, S.3
  • 40
    • 0033591311 scopus 로고    scopus 로고
    • Pindolol potentiates the effect of fluoxetine on hippocampal seizures in rats
    • Wada Y., Hirao N., Shiraishi J., et al. Pindolol potentiates the effect of fluoxetine on hippocampal seizures in rats. Neurosci Lett 267 1 (1999) 61-64
    • (1999) Neurosci Lett , vol.267 , Issue.1 , pp. 61-64
    • Wada, Y.1    Hirao, N.2    Shiraishi, J.3
  • 41
    • 0029431596 scopus 로고
    • Anticonvulsant effect of fluoxetine in humans
    • Favale E., Rubino V., Mainardi P., et al. Anticonvulsant effect of fluoxetine in humans. Neurology 45 10 (1995) 1926-1927
    • (1995) Neurology , vol.45 , Issue.10 , pp. 1926-1927
    • Favale, E.1    Rubino, V.2    Mainardi, P.3
  • 42
    • 0031011626 scopus 로고    scopus 로고
    • Anticonvulsant doses of carbamazepine increase hippocampal extracellular serotonin in genetically epilepsy-prone rats: dose response relationships
    • Dailey J.W., Reith M.E., Yan Q.S., et al. Anticonvulsant doses of carbamazepine increase hippocampal extracellular serotonin in genetically epilepsy-prone rats: dose response relationships. Neurosci Lett 227 1 (1997) 13-16
    • (1997) Neurosci Lett , vol.227 , Issue.1 , pp. 13-16
    • Dailey, J.W.1    Reith, M.E.2    Yan, Q.S.3
  • 43
    • 33645018161 scopus 로고    scopus 로고
    • Evidence supporting a role of serotonin in modulation of sudden death induced by seizures in DBA/2 mice
    • Tupal S., and Faingold C.L. Evidence supporting a role of serotonin in modulation of sudden death induced by seizures in DBA/2 mice. Epilepsia 47 (2006) 21-26
    • (2006) Epilepsia , vol.47 , pp. 21-26
    • Tupal, S.1    Faingold, C.L.2
  • 44
    • 0031456285 scopus 로고    scopus 로고
    • Sudden unexplained death in epilepsy: an intracranially monitored case
    • Bird J.M., Dembney K.A.T., Sandeman D., et al. Sudden unexplained death in epilepsy: an intracranially monitored case. Epilepsia 38 (1997) S52-S56
    • (1997) Epilepsia , vol.38
    • Bird, J.M.1    Dembney, K.A.T.2    Sandeman, D.3
  • 45
    • 0032778598 scopus 로고    scopus 로고
    • Partial seizures manifesting as apnea only in an adult
    • Lee H.W., Hong S.B., Tae W.S., et al. Partial seizures manifesting as apnea only in an adult. Epilepsia 40 (1999) 1828-1831
    • (1999) Epilepsia , vol.40 , pp. 1828-1831
    • Lee, H.W.1    Hong, S.B.2    Tae, W.S.3
  • 46
    • 36849060548 scopus 로고    scopus 로고
    • Sudden death in epilepsy recorded in ambulatory EEG
    • McLean B.N., and Wimalaratna S. Sudden death in epilepsy recorded in ambulatory EEG. J Neurol Neurosurg Psychiatr 78 (2007) 1395-1397
    • (2007) J Neurol Neurosurg Psychiatr , vol.78 , pp. 1395-1397
    • McLean, B.N.1    Wimalaratna, S.2
  • 47
    • 0033761626 scopus 로고    scopus 로고
    • Postictal central apnea as a cause of SUDEP: evidence from near-SUDEP incident
    • So E.L., Sam M.C., and Lagerlund T.L. Postictal central apnea as a cause of SUDEP: evidence from near-SUDEP incident. Epilepsia 41 (2000) 1494-1497
    • (2000) Epilepsia , vol.41 , pp. 1494-1497
    • So, E.L.1    Sam, M.C.2    Lagerlund, T.L.3
  • 48
    • 0030424320 scopus 로고    scopus 로고
    • Syncope anoxo-ischémique par dyspnée obstructive au cours d'une crise partielle complexe temporale droite
    • Thomas P., Landré E., Suisse G., et al. Syncope anoxo-ischémique par dyspnée obstructive au cours d'une crise partielle complexe temporale droite. Epilepsies 8 (1996) 339-346
    • (1996) Epilepsies , vol.8 , pp. 339-346
    • Thomas, P.1    Landré, E.2    Suisse, G.3
  • 49
    • 62949246675 scopus 로고    scopus 로고
    • Intracranial stimulation therapy for epilepsy
    • Skarpaas T.L., and Morrell M.J. Intracranial stimulation therapy for epilepsy. Neurotherapeutics 6 2 (2009) 238-243
    • (2009) Neurotherapeutics , vol.6 , Issue.2 , pp. 238-243
    • Skarpaas, T.L.1    Morrell, M.J.2
  • 50
    • 58149133768 scopus 로고    scopus 로고
    • Ictal hypoxemia in localization-related epilepsy: analysis of incidence, severity and risk factors
    • (3):199-203
    • Bateman L.M., Li C.S., and Seyal M. Ictal hypoxemia in localization-related epilepsy: analysis of incidence, severity and risk factors. Brain 131 Pt 12 (2008) 3239-3245 (3):199-203
    • (2008) Brain , vol.131 , Issue.PART 12 , pp. 3239-3245
    • Bateman, L.M.1    Li, C.S.2    Seyal, M.3


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