Structure-guided development of selective TbcatB inhibitors

Journal of Medicinal Chemistry

Volumn 52, Issue 20, 2009, Pages 6489-6493

  Mallari, Jeremy P ^a,b   Shelat, Anang A ^b   Kosinski, Aaron ^b   Caffrey, Conor R ^c   Connelly, Michele ^b   Zhu, Fangyi ^b   McKerrow, James H ^c   Kiplin Guy, R ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN B; CATHEPSIN B INHIBITOR; CATHEPSIN L;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG INHIBITION; DRUG POTENCY; DRUG STRUCTURE; DRUG TARGETING; ENZYME ACTIVITY; HUMAN; HUMAN CELL;

ANIMALS; CATHEPSIN B; CATHEPSIN L; CELL LINE; CYSTEINE ENDOPEPTIDASES; DRUG DISCOVERY; HUMANS; MODELS, MOLECULAR; PROTEASE INHIBITORS; PROTEIN CONFORMATION; PURINES; SUBSTRATE SPECIFICITY; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI;

EID: 70350057084     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm900908p     Document Type: Article

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