Intrinsic voltage dependence of the epithelial Na+ channel is masked by a conserved transmembrane domain tryptophan

Journal of Biological Chemistry

Volumn 284, Issue 38, 2009, Pages 25512-25521

  Pochynyuk, Oleh ^a   Kucher, Volodymyr ^a   Boiko, Nina ^a   Mironova, Elena ^a   Staruschenko, Alexander ^b   Karpushev, Alexey V ^b   Tong, Qiusheng ^a   Hendron, Eunan ^a   Stockand, James ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOCK MECHANISM; CHANNEL ACTIVITY; DIVALENT CATION; MACROSCOPIC CURRENTS; TRANS-MEMBRANE DOMAINS; TRYPTOPHAN RESIDUES; VOLTAGE DEPENDENCE; VOLTAGE SENSITIVITY; WATER INTERFACE;

ACTIVATION ANALYSIS; AMINES; AMINO ACIDS; APPLICATION SPECIFIC INTEGRATED CIRCUITS; CELL MEMBRANES; ORGANIC ACIDS;

BIOLOGICAL MEMBRANES;

CATION; CYSTEINE; EPITHELIAL SODIUM CHANNEL; GLUTAMIC ACID; GLYCINE; ISOLEUCINE; LYSINE; PHENYLALANINE; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRYPTOPHAN; VOLTAGE DEPENDENT ANION CHANNEL; ASIC CHANNEL; DEGENERIN EPITHELIAL SODIUM CHANNELS; NERVE PROTEIN; SODIUM CHANNEL;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DEPOLARIZATION; EVOKED RESPONSE; HYPERPOLARIZATION; MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; STEADY STATE; ANIMAL; CELL MEMBRANE POTENTIAL; CHO CELL; CRICETULUS; GENETICS; HAMSTER; METABOLISM; MISSENSE MUTATION; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

RATTUS;

AMINO ACID SUBSTITUTION; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; EPITHELIAL SODIUM CHANNEL; ION CHANNEL GATING; MEMBRANE POTENTIALS; MICE; MUTATION, MISSENSE; NERVE TISSUE PROTEINS; PROTEIN STRUCTURE, TERTIARY; RATS; SODIUM CHANNELS; TRYPTOPHAN;

EID: 70350023553     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.015917     Document Type: Article

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