Semiconductor quantum dots in chemical sensors and biosensors

Sensors

Volumn 9, Issue 9, 2009, Pages 7266-7286

  Frasco, Manuela F ^a   Chaniotakis, Nikos ^a  

^a UNIVERSITY OF CRETE   (Greece)

Author keywords

Nanoassembly; Optical sensors; Photoluminescence; Semiconductor quantum dots

Indexed keywords

LUMINESCENT QUANTUM DOTS; NANO-ASSEMBLIES; OPTICAL TRANSDUCTION; SEMICONDUCTOR CRYSTALS; SMALL MOLECULES; TARGET MOLECULE;

BIOSENSORS; CHEMICAL SENSORS; MOLECULES; NUCLEIC ACIDS; OPTICAL SENSORS; PHOTOLUMINESCENCE; SURFACE CHEMISTRY;

SEMICONDUCTOR QUANTUM DOTS;

EID: 70350004969     PISSN: 14248220     EISSN: None     Source Type: Journal    
DOI: 10.3390/s90907266     Document Type: Review

References (93)

1. Bruchez, M., Jr.; Moronne, M.; Gin, P.; Weiss, S.; Alivisatos, A.P. Semiconductor nanocrystals as fluorescent biological labels. Science 1998, 281, 2013-2016.
2. Chan, W.C.W.; Nie, S. Quantum dot bioconjugates for ultrasensitive nonisotopic detection. Science 1998, 281, 2016-2018.
3. Resch-Genger, U.; Grabolle, M.; Cavaliere-Jaricot, S.; Nitschke, R.; Nann, T. Quantum dots versus organic dyes as fluorescent labels. Nat. Methods 2008, 5, 763-775.
4. Weller, H. Colloidal semiconductor Q-particles: Chemistry in the transition region between solid state and molecules. Angew. Chem. Int. Ed. 1993, 32, 41-53.
5. Murphy, C.J. Optical sensing with quantum dots. Anal. Chem. 2002, 74, 520A-526A.
6. Dabbousi, B.O.; Rodriguez-Viejo, J.; Mikulec, F.V.; Heine, J.R.; Mattoussi, H.; Ober, R.; Jensen, K.F.; Bawendi, M.G. (CdSe)ZnS core-shell quantum dots: Synthesis and characterization of a size series of highly luminescent nanocrystallites. J. Phys. Chem. B 1997, 101, 9463-9475.
7. Jaiswal, J.K.; Mattoussi, H.; Mauro, J.M.; Simon, S.M. Long-term multiple color imaging of live cells using quantum dot bioconjugates. Nat. Biotechnol. 2003, 21, 47-51.
8. Murray, C.B.; Norris, D.J.; Bawendi, M.G. Synthesis and characterization of nearly monodisperse CdE (E = sulphur, selenium, tellurium) semiconductor nanocrystallites. J. Am. Chem. Soc. 1993, 115, 8706-8715.
9. Park, J.; Joo, J.; Kwon, S.G.; Jang, Y.; Hyeon, T. Synthesis of monodisperse spherical nanocrystals. Angew. Chem. Int. Ed. 2007, 46, 4630-4660.
10. Reiss, P.; Protière, M.; Li, L. Core/shell semiconductor nanocrystals. Small 2009, 5, 154-168.
11. Smith, A.M.; Ruan, G.; Rhyner, M.N.; Nie, S. Engineering luminescent quantum dots for in vivo molecular and cellular imaging. Ann. Biomed. Eng. 2006, 34, 3-14.
12. Jamieson, T.; Bakhshi, R.; Petrova, D.; Pocock, R.; Imani, M.; Seifalian, A.M. Biological applications of quantum dots. Biomaterials 2007, 28, 4717-4732.
13. Delehanty, J.B.; Mattoussi, H.; Medintz, I.L. Delivering quantum dots into cells: strategies, progress and remaining issues. Anal. Bioanal. Chem. 2009, 393, 1091-1105.
14. Nie, S.; Xing, Y.; Kim, G.J.; Simons, J.W. Nanotechnology applications in cancer. Annu. Rev. Biomed. Eng. 2007, 9, 257-288.
15. Smith, A.M.; Duan, H.; Mohs, A.M.; Nie, S. Bioconjugated quantum dots for in vivo molecular and cellular imaging. Adv. Drug Deliv. Rev. 2008, 60, 1226-1240.
16. Medintz, I.L.; Mattoussi, H.; Clapp, A.R. Potential clinical applications of quantum dots. Int. J. Nanomed. 2008, 3, 151-167.
17. Drbohlavova, J.; Adam, V.; Kizek, R.; Hubalek, J. Quantum dots - characterization, preparation and usage in biological systems. Int. J. Mol. Sci. 2009, 10, 656-673.
18. Somers, R.C.; Bawendi, M.G.; Nocera, D.G. CdSe nanocrystal based chem.-/bio- sensors. Chem. Soc. Rev. 2007, 36, 579-591.
19. Gill, R.; Zayats, M.; Willner, I. Semiconductor quantum dots for bioanalysis. Angew. Chem. Int. Ed. 2008, 47, 7602-7625.
20. Clapp, A.R.; Medintz, I.L.; Mattoussi, H. Förster resonance energy transfer investigations using quantum-dot fluorophores. Chem. Phys. Chem. 2006, 7, 47-57.
21. Willard, D.M.; Mutschler, T.; Yu, M.; Jung, J.; Van Orden, A. Directing energy flow through quantum dots: Towards nanoscale sensing. Anal. Bioanal. Chem. 2006, 384, 564-571.
22. Willard, D.M.; Carillo, L.L.; Jung, J.; Van Orden, A. CdSe-ZnS quantum dots as resonance energy transfer donors in a model protein-protein binding assay. Nano Lett. 2001, 1, 469-474.
23. Clapp, A.R.; Medintz, I.L.; Fisher, B.R.; Anderson, G.P.; Mattoussi, H. Can luminescent quantum dots be efficient energy acceptors with organic dye donors? J. Am. Chem. Soc. 2005, 127, 1242-1250.
24. Anni, M.; Manna, L.; Cingolani, R.; Valerini, D.; Cretí, A.; Lomascolo, M. Förster energy transfer from blue-emitting polymers to colloidal CdSe/ZnS core shell quantum dots. Appl. Phys. Lett. 2004, 85, 4169-4171.
25. So, M.-K.; Xu, C.; Loening, A.M.; Gambhir, S.S.; Rao, J. Self-illuminating quantum dot conjugates for in vivo imaging. Nat. Biotechnol. 2006, 24, 339-343.
26. Tomasulo, M.; Yildiz, I.; Kaanumalle, S.L.; Raymo, F.M. pH-sensitive ligand for luminescent quantum dots. Langmuir 2006, 22, 10284-10290.
27. Snee, P.T.; Somers, R.C.; Nair, G.; Zimmer, J.P.; Bawendi, M.G.; Nocera, D.G. A ratiometric CdSe/ZnS nanocrystal pH sensor. J. Am. Chem. Soc. 2006, 128, 13320-13321.
28. Susha, A.S.; Javier, A.M.; Parak, W.J.; Rogach, A.L. Luminescent CdTe nanocrystals as ion probes and pH sensors in aqueous solutions. Colloid. Surf. A 2006, 281, 40-43.
29. Liu, Y.-S.; Sun, Y.; Vernier, P.T.; Liang, C.-H.; Chong, S.Y.C.; Gundersen, M.A. pH-sensitive photoluminescence of CdSe/ZnSe/ZnS quantum dots in human ovarian cancer cells. J. Phys. Chem. C 2007, 111, 2872-2878.
30. Yu, D.; Wang, Z.; Liu, Y.; Jin, L.; Cheng, Y.; Zhou, J.; Cao, S. Quantum dot-based pH probe for quick study of enzyme reaction kinetics. Enzyme Microb. Technol. 2007, 41, 127-132.
31. Wang, Y.-Q.; Ye, C.; Zhu, Z.-H.; Hu, Y.-Z. Cadmium telluride quantum dots as pH-sensitive probes for tiopronin determination. Anal. Chim. Acta 2008, 610, 50-56.
32. Huang, C.-P.; Li, Y.-K.; Chen, T.-M. A highly sensitive system for urea detection by using CdSe/ZnS core-shell quantum dots. Biosens. Bioelectron. 2007, 22, 1835-1838.
33. 2+ probe. Spectrochim. Acta A 2004, 60, 2527-2530.
34. Li, H.; Zhang, Y.; Wang, X.; Gao, Z. A luminescent nanosensor for Hg(II) based on functionalized CdSe/ZnS quantum dots. Microchim. Acta 2008, 160, 119-123.
35. Chen, Y.; Rosenzweig, Z. Luminescent CdS quantum dots as selective ion probes. Anal. Chem. 2002, 74, 5132-5138.
36. Wang, X.; Ruedas-Rama, M.J.; Hall, E.A.H. The emerging use of quantum dots in analysis. Anal. Lett. 2007, 40, 1497-1520.
37. 2+ salt introduction. Langmuir 2001, 17, 2541-2544.
38. Zhang, Y.-H.; Zhang, H.-S.; Ma, M.; Guo, X.-F.; Wang, H. The influence of ligands on the preparation and optical properties of water-soluble CdTe quantum dots. Appl. Surf. Sci. 2009, 255, 4747-4753.
39. 2+ ions. Mater. Lett. 2007, 61, 1474-1477.
40. Li, J.; Mei, F.; Li, W.-Y.; He, X.-W.; Zhang, Y.-K. Study on the fluorescence resonance energy transfer between CdTe QDs and butyl-rhodamine B in the presence of CTMAB and its application on the detection of Hg(II). Spectrochim. Acta A 2008, 70, 811-817.
41. Ruedas-Rama, M.J.; Hall, E.A.H. Azamacrocycle activated quantum dot for zinc ion detection. Anal. Chem. 2008, 80, 8260-8268.
42. Jin, W.J.; Fernández-Argüelles, M.T.; Costa-Fernández, J.M.; Pereiro, R.; Sanz-Medel, A. Photoactivated luminescent CdSe quantum dots as sensitive cyanide probes in aqueous solutions. Chem. Commun. 2005, 883-885.
43. Callan, J.F.; Mulrooney, R.C.; Kamila, S.; McCaughan, B. Anion sensing with luminescent quantum dots-a modular approach based on the photoinduced electron transfer (PET) mechanism. J. Fluoresc. 2008, 18, 527-532.
44. Gattás-Asfura, K.M.; Leblanc, R.M. Peptide-coated CdS quantum dots for the optical detection of copper(II) and silver(I). Chem. Commun. 2003, 2684-2685.
45. Singh, N.; Mulrooney, R.C.; Kaur, N.; Callan, J.F. A nanoparticle based chromogenic chemosensor for the simultaneous detection of multiple analytes. Chem. Commun. 2008, 4900-4902, doi:10.1039/b813423e.
46. Shang, Z.B.; Wang, Y.; Jin, W.J. Triethanolamine-capped CdSe quantum dots as fluorescent sensors for reciprocal recognition of mercury(II) and iodide in aqueous solution. Talanta 2009, 78, 364-369.
47. Vinayaka, A.C.; Basheer, S.; Thakur, M.S. Bioconjugation of CdTe quantum dot for the detection of 2,4-dichlorophenoxyacetic acid by competitive fluoroimmunoassay based biosensor. Biosens. Bioelectron. 2009, 24, 1615-1620.
48. Ji, X.; Zheng, J.; Xu, J.; Rastogi, V.K.; Cheng, T.-C.; DeFrank, J.J.; Leblanc, R.M. (CdSe)ZnS quantum dots and organophosphorus hydrolase bioconjugate as biosensors for detection of paraoxon. J. Phys. Chem. B 2005, 109, 3793-3799.
49. Gill, R.; Bahshi, L.; Freeman, R.; Willner, I. Optical detection of glucose and acetylcholine esterase inhibitors by H2O2-sensitive CdSe/ZnS quantum dots. Angew. Chem. Int. Ed. 2008, 47, 1676-1679.
50. Liang, J.-G.; Zhang, S.-S.; Ai, X.-P.; Ji, X.-H.; He, Z.-K. The interaction between some diamines and CdSe quantum dots. Spectrochim. Acta A 2005, 61, 2974-2978.
51. Shi, G.H.; Shang, Z.B.; Wang, Y.; Jin, W.J.; Zhang, T.C. Fluorescence quenching of CdSe quantum dots by nitroaromatic explosives and their relative compounds. Spectrochim. Acta A 2008, 70, 247-252.
52. Goldman, E.R.; Medintz, I.L.; Whitley, J.L.; Hayhurst, A.; Clapp, A.R.; Uyeda, H.T.; Deschamps, J.R.; Lassman, M.E.; Mattoussi, H. A hybrid quantum dot-antibody fragment fluorescence resonance energy transfer-based TNT sensor. J. Am. Chem. Soc. 2005, 127, 6744-6751.
53. Hamity, M.; Lema, R.H.; Suchetti, C.A. The effect of tetraalkylammonium and alkyl sulphate salts on the fluorescence bands of quantum-sized CdS. J. Photochem. Photobiol. A: Chem. 1998, 115, 163-168.
54. Diao, X.-L.; Xia, Y.-S.; Zhang, T.-L.; Li, Y.; Zhu, C.-Q. Fluorescence-detecting cationic surfactants using luminescent CdTe quantum dots as probes. Anal. Bioanal. Chem. 2007, 388, 1191-1197.
55. Qu, F.; Li, H. Selective molecular recognition of polycyclic aromatic hydrocarbons using CdTe quantum dots with cyclodextrin as supramolecular nano-sensitizers in water. Sens. Actuators B: Chem. 2009, 135, 499-505.
56. Yeh, H.-C.; Ho, Y.-P.; Wang, T.-H. Quantum dot-mediated biosensing assays for specific nucleic acid detection. Nanomed.: Nanotechnol. Biol. Med. 2005, 1, 115-121.
57. Dyadyusha, L.; Yin, H.; Jaiswal, S.; Brown, T.; Baumberg, J.J.; Booy, F.P.; Melvin, T. Quenching of CdSe quantum dot emission, a new approach for biosensing. Chem. Commun. 2005, 3201-3203, doi:10.1039/b500664c.
58. Zhao, D.; Jimei, Z.; Quanxi, D.; Ning, D.; Shichao, X.; Bo, S.; Yuehua, B. Adaption of Au nanoparticles and CdTe quantum dots in DNA detection. Chin. J. Chem. Eng. 2007, 15, 791-794.
59. Gill, R.; Willner, I.; Shweky, I.; Banin, U. Fluorescence resonance energy transfer in CdSe/ZnS- DNA conjugates: Probing hybridization and DNA cleavage. J. Phys. Chem. B 2005, 109, 23715-23719.
60. Patolsky, F.; Gill, R.; Weizmann, Y.; Mokari, T.; Banin, U.; Willner, I. Lighting-up the dynamics of telomerization and DNA replication by CdSe-ZnS quantum dots. J. Am. Chem. Soc. 2003, 125, 13918-13919.
61. Peng, H.; Zhang, L.; Kjällman, T.H.M.; Soeller, C.; Travas-Sejdic, J. DNA hybridization detection with blue luminescent quantum dots and dye-labeled single-stranded DNA. J. Am. Chem. Soc. 2007, 129, 3048-3049.
62. Yuan, J.; Guo, W.; Yang, X.; Wang, E. Anticancer drug - DNA interactions measured using a photoinduced electron-transfer mechanism based on luminescent quantum dots. Anal. Chem. 2009, 81, 362-368.
63. Pathak, S.; Choi, S.-K.; Arnheim, N.; Thompson, M.E. Hydroxylated quantum dots as luminescent probes for in situ hybridization. J. Am. Chem. Soc. 2001, 123, 4103-4104.
64. Gerion, D.; Chen, F.; Kannan, B.; Fu, A.; Parak, W.J.; Chen, D. J.; Majumdar, A.; Alivisatos, A.P. Room-temperature single-nucleotide polymorphism and multiallele DNA detection using fluorescent nanocrystals and microarrays. Anal. Chem. 2003, 75, 4766-4772.
65. Zhang, C.-Y.; Johnson, L.W. Quantum-dot-based nanosensor for RRE IIB RNA-Rev peptide interaction assay. J. Am. Chem. Soc. 2006, 128, 5324-5325.
66. Medintz, I.L.; Berti, L.; Pons, T.; Grimes, A.F.; English, D.S.; Alessandrini, A.; Facci, P.; Mattoussi, H. A reactive peptidic linker for self-assembling hybrid quantum dot-DNA bioconjugates. Nano Lett. 2007, 7, 1741-1748.
67. Mattoussi, H.; Mauro, J.M.; Goldman, E.R.; Anderson, G.P.; Sundar, V.C.; Mikulec, F.V.; Bawendi, M.G. Self-assembly of CdSe-ZnS quantum dot bioconjugates using an engineered recombinant protein. J. Am. Chem. Soc. 2000, 122, 12142-12150.
68. Goldman, E.R.; Balighian, E.D.; Kuno, M.K.; Labrenz, S.; Tran, P.T.; Anderson, G.P.; Mauro, J.M.; Mattoussi, H. Luminescent quantum dot-adaptor protein-antibody conjugates for use in fluoroimmunoassays. Phys. Stat. Sol. B 2002, 229, 407-414.
69. Goldman, E.R.; Clapp, A.R.; Anderson, G.P.; Uyeda, H.T.; Mauro, J.M.; Medintz, I.L.; Mattoussi, H. Multiplexed toxin analysis using four colors of quantum dot fluororeagents. Anal. Chem. 2004, 76, 684-688.
70. Lao, U.L.; Mulchandani, A.; Chen, W. Simple conjugation and purification of quantum dot- antibody complexes using a thermally responsive elastin-protein L scaffold as immunofluorescent agents. J. Am. Chem. Soc. 2006, 128, 14756-14757.
71. Huang, S.; Xiao, Q.; He, Z.K.; Liu, Y.; Tinnefeld, P.; Su, X.R.; Peng, X.N. A high sensitive and specific QDs FRET bioprobe for MNase. Chem. Commun. 2008, 5990-5992.
72. Chang, E.; Miller, J.S.; Sun, J.; Yu, W.W.; Colvin, V.L.; Drezek, R.; West, J.L. Protease-activated quantum dot probes. Biochem. Biophys. Res. Commun. 2005, 334, 1317-1321.
73. Medintz, I.L.; Clapp, A.R.; Brunel, F.M.; Tiefenbrunn, T.; Uyeda, H.T.; Chang, E.L.; Deschamps, J.R.; Dawson, P.E.; Mattoussi, H. Proteolytic activity monitored by fluorescence resonance energy transfer through quantum-dot-peptide conjugates. Nat. Mater. 2006, 5, 581-589.
74. Boeneman, K.; Mei, B.C.; Dennis, A.M.; Bao, G.; Deschamps, J.R.; Mattoussi, H.; Medintz, I.L. Sensing caspase 3 activity with quantum dot-fluorescent protein assemblies. J. Am. Chem. Soc. 2009, 131, 3828-3829.
75. Choi, J.H.; Chen, K.H.; Strano, M.S. Aptamer-capped nanocrystal quantum dots: a new method for label-free protein detection. J. Am. Chem. Soc. 2006, 128, 15584-15585.
76. Levy, M.; Cater, S.F.; Ellington, A.D. Quantum-dot aptamer beacons for the detection of proteins. ChemBioChem 2005, 6, 2163-2166.
77. Yildiz, I.; Tomasulo, M.; Raymo, F.M. A mechanism to signal receptor-substrate interactions with luminescent quantum dots. Proc. Natl. Acad. Sci. USA 2006, 103, 11457-11460.
78. Zhang, Y.; So, M.-K.; Loening, A.M.; Yao, H.; Gambhir, S.S.; Rao, J. HaloTag protein-mediated site-specific conjugation of bioluminescent proteins to quantum dots. Angew. Chem. Int. Ed. 2006, 45, 4936-4940.
79. Xia, Z.; Xing, Y.; So, M.-K.; Koh, A.L.; Sinclair, R.; Rao, J. Multiplex detection of protease activity with quantum dot nanosensors prepared by intein-mediated specific bioconjugation. Anal. Chem. 2008, 80, 8649-8655.
80. Ma, Q.; Wang, X.; Li, Y.; Shi, Y.; Su, X. Multicolor quantum dot-encoded microspheres for the detection of biomolecules. Talanta 2007, 72, 1446-1452.
81. Suzuki, M.; Husimi, Y.; Komatsu, H.; Suzuki, K.; Douglas, K.T. Quantum dot FRET biosensors that respond to pH, to proteolytic or nucleolytic cleavage, to DNA synthesis, or to a multiplexing combination. J. Am. Chem. Soc. 2008, 130, 5720-5725.
82. Huang, S.; Xiao, Q.; Li, R.; Guan, H.-L.; Liu, J.; Liu, X.-R.; He, Z.-K.; Liu, Y. A simple and sensitive method for L-cysteine detection based on the fluorescence intensity increment of quantum dots. Anal. Chim. Acta 2009, 645, 73-78.
83. Wang, X.; Wu, J.; Li, F.; Li, H. Synthesis of water-soluble CdSe quantum dots by ligand exchange with p-sulfonatocalix(n)arene (n = 4, 6) as fluorescent probes for amino acids. Nanotechnology 2008, 19, 205501:1-205501:8.
84. Han, C.; Li, H. Chiral recognition of amino acids based on cyclodextrin-capped quantum dots. Small 2008, 4, 1344-1350.
85. Liang, J.; Huang, S.; Zeng, D.; He, Z.; Ji, Z.; Ai, X.; Yang, H. CdSe quantum dots as luminescent probes for spironolactone determination. Talanta 2006, 69, 126-130.
86. He, Y.; Wang, H.-F.; Yan, X.-P. Exploring Mn-doped ZnS quantum dots for the room- temperature phosphorescence detection of enoxacin in biological fluids. Anal. Chem. 2008, 80, 3832-3837.
87. Liu, J.; Lee, J.H.; Lu, Y. Quantum dot encoding of aptamer-linked nanostructures for one-pot simultaneous detection of multiple analytes. Anal. Chem. 2007, 79, 4120-4125.
88. Callan, J.F.; Mulrooney, R.C.; Kamila, S. Luminescent detection of ATP in aqueous solution using positively charged CdSe-ZnS quantum dots. J. Fluoresc. 2008, 18, 1157-1161.
89. Jin, T.; Fujii, F.; Sakata, H.; Tamura, M.; Kinjo, M. Amphiphilic p-sulfonatocalix[4]arene-coated CdSe/ZnS quantum dots for the optical detection of the neurotransmitter acetylcholine. Chem. Commun. 2005, 4300-4302.
90. Medintz, I.L.; Clapp, A.R.; Mattoussi, H.; Goldman, E.R.; Fisher, B.; Mauro, J.M. Self-assembled nanoscale biosensors based on quantum dot FRET donors. Nat. Mater. 2003, 2, 630-638.
91. Sapsford, K.E.; Medintz, I.L.; Golden, J.P.; Deschamps, J.R.; Uyeda, H.T.; Mattoussi, H. Surface- immobilized self-assembled protein-based quantum dot nanoassemblies. Langmuir 2004, 20, 7720-7728.
92. Medintz, I.L.; Sapsford, K.E.; Clapp, A.R.; Pons, T.; Higashiya, S.; Welch, J.T.; Mattoussi, H. Designer variable repeat length polypeptides as scaffolds for surface immobilization of quantum dots. J. Phys. Chem. B 2006, 110, 10683-10690.
93. Cao, L.; Ye, J.; Tong, L.; Tang, B. A new route to the considerable enhancement of glucose oxidase (GOx) activity: The simple assembly of a complex from CdTe quantum dots and GOx and its glucose sensing. Chem. Eur. J. 2008, 14, 9633-9640.