Influenza virus CTL epitopes, remarkably conserved and remarkably variable

Vaccine

Volumn 27, Issue 45, 2009, Pages 6363-6365

  Rimmelzwaan, Guus F ^a   Kreijtz, Joost H C M ^a   Bodewes, Rogier ^a   Fouchier, Ron A M ^a   Osterhaus, Albert D M E ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Cytotoxic T lymphocytes; Epitopes; Influenza A virus

Indexed keywords

EPITOPE; HLA A ANTIGEN; HLA B ANTIGEN; HLA B0801 ANTIGEN; HLA B1503 ANTIGEN; HLA B2705 ANTIGEN; HLA B3501 ANTIGEN; HLA B4002 ANTIGEN; MATRIX PROTEIN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANTIGEN RECOGNITION; ANTIGENIC VARIATION; ARTICLE; CYTOTOXIC T LYMPHOCYTE; EPIDEMIC; GENETIC CONSERVATION; GENETIC VARIABILITY; HUMORAL IMMUNITY; IMMUNOGLOBULIN VARIABLE REGION; INFECTION CONTROL; INFLUENZA VIRUS A; INFLUENZA VIRUS A H3N2; INFLUENZA VIRUS A H5N1; MUTATIONAL ANALYSIS; NONHUMAN; PANDEMIC; PRIORITY JOURNAL;

AMINO ACID SUBSTITUTION; EPITOPES, T-LYMPHOCYTE; EVOLUTION, MOLECULAR; GENETIC VARIATION; HLA-B ANTIGENS; INFLUENZA A VIRUS, H3N2 SUBTYPE; MUTATION; SEQUENCE ANALYSIS, PROTEIN; T-LYMPHOCYTES, CYTOTOXIC;

EID: 70349976425     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.01.016     Document Type: Article

References (28)

1. Alcami A., and Koszinowski U.H. Viral mechanisms of immune evasion. Immunol Today 21 September (9) (2000) 447-455
2. Lybarger L., Wang X., Harris M., and Hansen T.H. Viral immune evasion molecules attack the ER peptide-loading complex and exploit ER-associated degradation pathways. Curr Opin Immunol 17 February (1) (2005) 71-78
3. Pinto A.K., and Hill A.B. Viral interference with antigen presentation to CD8+ T cells: lessons from cytomegalovirus. Viral Immunol 18 3 (2005) 434-444
4. Tortorella D., Gewurz B.E., Furman M.H., Schust D.J., and Ploegh H.L. Viral subversion of the immune system. Annu Rev Immunol 18 (2000) 861-926
5. Vossen M.T., Westerhout E.M., Soderberg-Naucler C., and Wiertz E.J. Viral immune evasion: a masterpiece of evolution. Immunogenetics 54 November (8) (2002) 527-542
6. Yewdell J.W., and Hill A.B. Viral interference with antigen presentation. Nat Immunol 3 November (11) (2002) 1019-1025
7. Holmes E.C. Error thresholds and the constraints to RNA virus evolution. Trends Microbiol 11 December (12) (2003) 543-546
8. Smith D.J., Lapedes A.S., de Jong J.C., Bestebroer T.M., Rimmelzwaan G.F., Osterhaus A.D., et al. Mapping the antigenic and genetic evolution of influenza virus. Science 305 July (5682) (2004) 371-376
9. Voeten J.T., Bestebroer T.M., Nieuwkoop N.J., Fouchier R.A., Osterhaus A.D., and Rimmelzwaan G.F. Antigenic drift in the influenza A virus (H3N2) nucleoprotein and escape from recognition by cytotoxic T lymphocytes. J Virol 74 August (15) (2000) 6800-6807
10. Rimmelzwaan G.F., Boon A.C., Voeten J.T., Berkhoff E.G., Fouchier R.A., and Osterhaus A.D. Sequence variation in the influenza A virus nucleoprotein associated with escape from cytotoxic T lymphocytes. Virus Res 103 July (1-2) (2004) 97-100
11. Gog J.R., Rimmelzwaan G.F., Osterhaus A.D., and Grenfell B.T. Population dynamics of rapid fixation in cytotoxic T lymphocyte escape mutants of influenza A. Proc Natl Acad Sci USA 100 September (19) (2003) 11143-11147
12. Berkhoff E.G., Boon A.C., Nieuwkoop N.J., Fouchier R.A., Sintnicolaas K., Osterhaus A.D., et al. A mutation in the HLA-B*2705-restricted NP383-391 epitope affects the human influenza A virus-specific cytotoxic T-lymphocyte response in vitro. J Virol 78 May (10) (2004) 5216-5222
13. Rimmelzwaan G.F., Berkhoff E.G., Nieuwkoop N.J., Fouchier R.A., and Osterhaus A.D. Functional compensation of a detrimental amino acid substitution in a cytotoxic-T-lymphocyte epitope of influenza a viruses by comutations. J Virol 78 August (16) (2004) 8946-8949
14. Rimmelzwaan G.F., Berkhoff E.G., Nieuwkoop N.J., Smith D.J., Fouchier R.A., and Osterhaus A.D. Full restoration of viral fitness by multiple compensatory co-mutations in the nucleoprotein of influenza A virus cytotoxic T-lymphocyte escape mutants. J Gen Virol 86 June (Pt 6) (2005) 1801-1805
15. Portela A., and Digard P. The influenza virus nucleoprotein: a multifunctional RNA-binding protein pivotal to virus replication. J Gen Virol 83 April (Pt 4) (2002) 723-734
16. Boon A.C., de Mutsert G., Graus Y.M., Fouchier R.A., Sintnicolaas K., Osterhaus A.D., et al. Sequence variation in a newly identified HLA-B35-restricted epitope in the influenza A virus nucleoprotein associated with escape from cytotoxic T lymphocytes. J Virol 76 March (5) (2002) 2567-2572
17. Boon A.C., de Mutsert G., van Baarle D., Smith D.J., Lapedes A.S., Fouchier R.A., et al. Recognition of homo- and heterosubtypic variants of influenza A viruses by human CD8+ T lymphocytes. J Immunol 172 February (4) (2004) 2453-2460
18. Berkhoff E.G., Geelhoed-Mieras M.M., Verschuren E.J., van Baalen C.A., Gruters R.A., Fouchier R.A., et al. The loss of immunodominant epitopes affects interferon-gamma production and lytic activity of the human influenza virus-specific cytotoxic T lymphocyte response in vitro. Clin Exp Immunol 148 May (2) (2007) 296-306
19. Boon A.C., de Mutsert G., Fouchier R.A., Osterhaus A.D., and Rimmelzwaan G.F. The hypervariable immunodominant NP418-426 epitope from the influenza A virus nucleoprotein is recognized by cytotoxic T lymphocytes with high functional avidity. J Virol 80 June (12) (2006) 6024-6032
20. Berkhoff E.G., Geelhoed-Mieras M.M., Fouchier R.A., Osterhaus A.D., and Rimmelzwaan G.F. Assessment of the extent of variation in influenza A virus cytotoxic T-lymphocyte epitopes by using virus-specific CD8+ T-cell clones. J Gen Virol 88 February (Pt 2) (2007) 530-535
21. Berkhoff E.G., de Wit E., Geelhoed-Mieras M.M., Boon A.C., Symons J., Fouchier R.A., et al. Functional constraints of influenza A virus epitopes limit escape from cytotoxic T lymphocytes. J Virol 79 September (17) (2005) 11239-11246
22. Kreijtz J.H., de Mutsert G., van Baalen C.A., Fouchier R.A., Osterhaus A.D., and Rimmelzwaan G.F. Cross-recognition of avian H5N1 influenza virus by human cytotoxic T-lymphocyte populations directed to human influenza A virus. J Virol 82 June (11) (2008) 5161-5166
23. Jameson J., Cruz J., and Ennis F.A. Human cytotoxic T-lymphocyte repertoire to influenza A viruses. J Virol 72 November (11) (1998) 8682-8689
24. Jameson J., Cruz J., Terajima M., and Ennis F.A. Human CD8+ and CD4+ T lymphocyte memory to influenza A viruses of swine and avian species. J Immunol 162 June (12) (1999) 7578-7583
25. Kreijtz J.H., Bodewes R., van Amerongen G., Kuiken T., Fouchier R.A., Osterhaus A.D., et al. Primary influenza A virus infection induces cross-protective immunity against a lethal infection with a heterosubtypic virus strain in mice. Vaccine 25 January (4) (2007) 612-620
26. Grebe K.M., Yewdell J.W., and Bennink J.R. Heterosubtypic immunity to influenza A virus: where do we stand?. Microbes Infect 10 July (9) (2008) 1024-1029
27. McMichael A.J., Gotch F.M., Noble G.R., and Beare P.A. Cytotoxic T-cell immunity to influenza. N Engl J Med 309 July (1) (1983) 13-17
28. Epstein S.L. Prior H1N1 influenza infection and susceptibility of Cleveland Family Study participants during the H2N2 pandemic of 1957: an experiment of nature. J Infect Dis 193 January (1) (2006) 49-53