Bayesian population analysis of a washin-washout physiologically based pharmacokinetic model for acetone

Toxicology and Applied Pharmacology

Volumn 240, Issue 3, 2009, Pages 423-432

  Mörk, Anna Karin ^a   Jonsson, Fredrik ^a,b   Johanson, Gunnar ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b CERTARA   (United States)

Author keywords

Bayesian analysis; Hierarchical model; Human; Markov chain Monte Carlo simulation; PBPK; Respiratory washin washout; Sensitivity analysis

Indexed keywords

ACETONE;

ARTERIAL BLOOD; ARTICLE; BAYES THEOREM; CONTROLLED STUDY; EXPIRED AIR; HUMAN; HUMAN EXPERIMENT; MALE; MONTE CARLO METHOD; NORMAL HUMAN; OCCUPATIONAL EXPOSURE; PHYSICAL STRESS; POPULATION EXPOSURE; QUANTITATIVE ANALYSIS; RISK ASSESSMENT; SENSITIVITY ANALYSIS; TOXICOKINETICS; VENOUS BLOOD; WORKLOAD;

ACETONE; BAYES THEOREM; HUMANS; MARKOV CHAINS; MODELS, THEORETICAL; MONTE CARLO METHOD; UNCERTAINTY;

EID: 70349966232     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.07.033     Document Type: Article

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