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Volumn 154, Issue 5, 2009, Pages 222-227

γδ T cells and Th17 cytokines in hypersensitivity pneumonitis and lung fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 22; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 70349956628     PISSN: 19315244     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trsl.2009.08.006     Document Type: Review
Times cited : (53)

References (59)
  • 1
    • 0142121237 scopus 로고    scopus 로고
    • Hypersensitivity pneumonitis
    • Schwarz M.I., and King Jr. T.E. (Eds), B.C. Decker, Hamilton, Canada
    • Selman M. Hypersensitivity pneumonitis. In: Schwarz M.I., and King Jr. T.E. (Eds). Interstitial lung disease. 3rd ed (2003), B.C. Decker, Hamilton, Canada 452-484
    • (2003) Interstitial lung disease. 3rd ed , pp. 452-484
    • Selman, M.1
  • 2
    • 37949013431 scopus 로고
    • Spore concentration in the air of farm buildings
    • Lacy J., and Lacey M.E. Spore concentration in the air of farm buildings. Trans Br Mycol Soc 47 (1964) 547-552
    • (1964) Trans Br Mycol Soc , vol.47 , pp. 547-552
    • Lacy, J.1    Lacey, M.E.2
  • 3
    • 0024385864 scopus 로고
    • Longitudinal course of extrinsic allergic alveolitis in pigeon breeders
    • Bourke S.J., Banham S.W., Carter R., Lynch P., and Boyd G. Longitudinal course of extrinsic allergic alveolitis in pigeon breeders. Thorax 44 (1989) 415-418
    • (1989) Thorax , vol.44 , pp. 415-418
    • Bourke, S.J.1    Banham, S.W.2    Carter, R.3    Lynch, P.4    Boyd, G.5
  • 4
    • 0027269650 scopus 로고
    • Farmer's lung. Long-term outcome and lack of predictive value of bronchoalveolar lavage fibrosing factors
    • Lalancette M., Carrier G., Laviolette M., et al. Farmer's lung. Long-term outcome and lack of predictive value of bronchoalveolar lavage fibrosing factors. Am Rev Respir Dis 148 (1993) 216-221
    • (1993) Am Rev Respir Dis , vol.148 , pp. 216-221
    • Lalancette, M.1    Carrier, G.2    Laviolette, M.3
  • 5
    • 85004795330 scopus 로고
    • Farmer's lung-a 5-year follow-up of eighty-six patients
    • Monkare S., and Haahtela T. Farmer's lung-a 5-year follow-up of eighty-six patients. Clin Allergy 17 (1987) 143-151
    • (1987) Clin Allergy , vol.17 , pp. 143-151
    • Monkare, S.1    Haahtela, T.2
  • 7
    • 2342644889 scopus 로고    scopus 로고
    • The effect of pulmonary fibrosis on survival in patients with hypersensitivity pneumonitis
    • Vourlekis J.S., Schwarz M.I., Cherniack R.M., et al. The effect of pulmonary fibrosis on survival in patients with hypersensitivity pneumonitis. Am J Med 116 (2004) 662-668
    • (2004) Am J Med , vol.116 , pp. 662-668
    • Vourlekis, J.S.1    Schwarz, M.I.2    Cherniack, R.M.3
  • 8
    • 0020066287 scopus 로고
    • The pulmonary pathology of farmer's lung disease
    • Reyes C.N., Wenzel F.J., Lawton B.R., and Emanuel D.A. The pulmonary pathology of farmer's lung disease. Chest 81 (1982) 142-146
    • (1982) Chest , vol.81 , pp. 142-146
    • Reyes, C.N.1    Wenzel, F.J.2    Lawton, B.R.3    Emanuel, D.A.4
  • 9
    • 0021967891 scopus 로고
    • Bronchoalveolar lavage and lung histology. Comparative analysis of inflammatory and immunocompetent cells in patients with sarcoidosis and hypersensitivity pneumonitis
    • Semenzato G., Chilosi M., Ossi E., et al. Bronchoalveolar lavage and lung histology. Comparative analysis of inflammatory and immunocompetent cells in patients with sarcoidosis and hypersensitivity pneumonitis. Am Rev Respir Dis 132 (1985) 400-404
    • (1985) Am Rev Respir Dis , vol.132 , pp. 400-404
    • Semenzato, G.1    Chilosi, M.2    Ossi, E.3
  • 10
    • 0017657420 scopus 로고
    • Immunopathogenesis of hypersensitivity pneumonitis
    • Roberts R.C., and Moore V.L. Immunopathogenesis of hypersensitivity pneumonitis. Am Rev Respir Dis 116 (1977) 1075-1090
    • (1977) Am Rev Respir Dis , vol.116 , pp. 1075-1090
    • Roberts, R.C.1    Moore, V.L.2
  • 13
    • 0033568179 scopus 로고    scopus 로고
    • Polarized type 1 cytokine profile in bronchoalveolar lavage t cells of patients with hypersensitivity pneumonitis
    • Yamasaki H., Ando M., Brazer W., Center D.M., and Cruikshank W.W. Polarized type 1 cytokine profile in bronchoalveolar lavage t cells of patients with hypersensitivity pneumonitis. J Immunol 163 (1999) 3516-3523
    • (1999) J Immunol , vol.163 , pp. 3516-3523
    • Yamasaki, H.1    Ando, M.2    Brazer, W.3    Center, D.M.4    Cruikshank, W.W.5
  • 14
    • 0026479567 scopus 로고
    • Murine hypersensitivity pneumonitis: a study of cellular infiltrates and cytokine production and its modulation by cyclosporin a
    • Denis M., Cormier Y., and Laviolette M. Murine hypersensitivity pneumonitis: a study of cellular infiltrates and cytokine production and its modulation by cyclosporin a. Am J Respir Cell Mol Biol 6 (1992) 68-74
    • (1992) Am J Respir Cell Mol Biol , vol.6 , pp. 68-74
    • Denis, M.1    Cormier, Y.2    Laviolette, M.3
  • 15
    • 0026812988 scopus 로고
    • T cells in hypersensitivity pneumonitis: effects of in vivo depletion of t cells in a mouse model
    • Denis M., Cormier Y., Laviolette M., and Ghadirian E. T cells in hypersensitivity pneumonitis: effects of in vivo depletion of t cells in a mouse model. Am J Respir Cell Mol Biol 6 (1992) 183-189
    • (1992) Am J Respir Cell Mol Biol , vol.6 , pp. 183-189
    • Denis, M.1    Cormier, Y.2    Laviolette, M.3    Ghadirian, E.4
  • 16
    • 59849115870 scopus 로고    scopus 로고
    • Th17-polarized immune response in a murine model of hypersensitivity pneumonitis and lung fibrosis
    • Simonian P.L., Roark C.L., Wehrmann F., et al. Th17-polarized immune response in a murine model of hypersensitivity pneumonitis and lung fibrosis. J Immunol 182 (2009) 657-665
    • (2009) J Immunol , vol.182 , pp. 657-665
    • Simonian, P.L.1    Roark, C.L.2    Wehrmann, F.3
  • 17
    • 0026710342 scopus 로고
    • Hypersensitivity pneumonitis in athymic nude mice. Additional evidence of t cell dependency
    • Takizawa H., Ohta K., Horiuchi T., et al. Hypersensitivity pneumonitis in athymic nude mice. Additional evidence of t cell dependency. Am Rev Respir Dis 146 (1992) 479-484
    • (1992) Am Rev Respir Dis , vol.146 , pp. 479-484
    • Takizawa, H.1    Ohta, K.2    Horiuchi, T.3
  • 18
    • 0023835163 scopus 로고
    • Experimental hypersensitivity pneumonitis in the mouse: histologic and immunologic features and their modulation with cyclosporin a
    • Takizawa H., Suko M., Kobayashi N., et al. Experimental hypersensitivity pneumonitis in the mouse: histologic and immunologic features and their modulation with cyclosporin a. J Allergy Clin Immunol 81 (1988) 391-400
    • (1988) J Allergy Clin Immunol , vol.81 , pp. 391-400
    • Takizawa, H.1    Suko, M.2    Kobayashi, N.3
  • 19
    • 0032707714 scopus 로고    scopus 로고
    • Th1 cells that adoptively transfer experimental hypersensitivity pneumonitis are activated memory cells
    • Schuyler M., Gott K., and Edwards B. Th1 cells that adoptively transfer experimental hypersensitivity pneumonitis are activated memory cells. Lung 177 (1999) 377-389
    • (1999) Lung , vol.177 , pp. 377-389
    • Schuyler, M.1    Gott, K.2    Edwards, B.3
  • 21
    • 0030962332 scopus 로고    scopus 로고
    • Interferon-gamma is necessary for the expression of hypersensitivity pneumonitis
    • Gudmundsson G., and Hunninghake G.W. Interferon-gamma is necessary for the expression of hypersensitivity pneumonitis. J Clin Invest 99 (1997) 2386-2390
    • (1997) J Clin Invest , vol.99 , pp. 2386-2390
    • Gudmundsson, G.1    Hunninghake, G.W.2
  • 22
    • 0032528531 scopus 로고    scopus 로고
    • Il-12 modulates expression of hypersensitivity pneumonitis
    • Gudmundsson G., Monick M.M., and Hunninghake G.W. Il-12 modulates expression of hypersensitivity pneumonitis. J Immunol 161 (1998) 991-999
    • (1998) J Immunol , vol.161 , pp. 991-999
    • Gudmundsson, G.1    Monick, M.M.2    Hunninghake, G.W.3
  • 23
    • 0036785587 scopus 로고    scopus 로고
    • Altered il-4 mrna stability correlates with th1 and th2 bias and susceptibility to hypersensitivity pneumonitis in two inbred strains of mice
    • Butler N.S., Monick M.M., Yarovinsky T.O., Powers L.S., and Hunninghake G.W. Altered il-4 mrna stability correlates with th1 and th2 bias and susceptibility to hypersensitivity pneumonitis in two inbred strains of mice. J Immunol 169 (2002) 3700-3709
    • (2002) J Immunol , vol.169 , pp. 3700-3709
    • Butler, N.S.1    Monick, M.M.2    Yarovinsky, T.O.3    Powers, L.S.4    Hunninghake, G.W.5
  • 24
    • 65249134949 scopus 로고    scopus 로고
    • Interleukin-17-mediated immunopathogenesis in experimental hypersensitivity pneumonitis
    • Joshi A.D., Fong D.J., Oak S.R., et al. Interleukin-17-mediated immunopathogenesis in experimental hypersensitivity pneumonitis. Am J Respir Crit Care Med 179 (2009) 705-716
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 705-716
    • Joshi, A.D.1    Fong, D.J.2    Oak, S.R.3
  • 25
    • 0037434789 scopus 로고    scopus 로고
    • Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
    • Cua D.J., Sherlock J., Chen Y., et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 421 (2003) 744-748
    • (2003) Nature , vol.421 , pp. 744-748
    • Cua, D.J.1    Sherlock, J.2    Chen, Y.3
  • 26
    • 33749134183 scopus 로고    scopus 로고
    • Regulatory role of gammadelta T cells in the recruitment of cd4+ and cd8+ t cells to lung and subsequent pulmonary fibrosis
    • Simonian P.L., Roark C.L., Diaz del Valle F., et al. Regulatory role of gammadelta T cells in the recruitment of cd4+ and cd8+ t cells to lung and subsequent pulmonary fibrosis. J Immunol 177 (2006) 4436-4443
    • (2006) J Immunol , vol.177 , pp. 4436-4443
    • Simonian, P.L.1    Roark, C.L.2    Diaz del Valle, F.3
  • 27
    • 70349946374 scopus 로고    scopus 로고
    • Il-17a-expressing t cells are essential for bacterial clearance in a murine model of hypersensitivity pneumonitis
    • Simonian P.L., Roark C.L., Wehrmann F., et al. Il-17a-expressing t cells are essential for bacterial clearance in a murine model of hypersensitivity pneumonitis. J Immunol 182 (2009) 6540-6549
    • (2009) J Immunol , vol.182 , pp. 6540-6549
    • Simonian, P.L.1    Roark, C.L.2    Wehrmann, F.3
  • 29
    • 0028176950 scopus 로고
    • Increased gamma/delta-positive t-cells in blood and bronchoalveolar lavage of patients with sarcoidosis and hypersensitivity pneumonitis
    • Raulf M., Liebers V., Steppert C., and Baur X. Increased gamma/delta-positive t-cells in blood and bronchoalveolar lavage of patients with sarcoidosis and hypersensitivity pneumonitis. Eur Respir J 7 (1994) 140-147
    • (1994) Eur Respir J , vol.7 , pp. 140-147
    • Raulf, M.1    Liebers, V.2    Steppert, C.3    Baur, X.4
  • 30
    • 0025188814 scopus 로고
    • Mechanisms accounting for lymphocytic alveolitis in hypersensitivity pneumonitis
    • Trentin L., Migone N., Zambello R., et al. Mechanisms accounting for lymphocytic alveolitis in hypersensitivity pneumonitis. J Immunol 145 (1990) 2147-2154
    • (1990) J Immunol , vol.145 , pp. 2147-2154
    • Trentin, L.1    Migone, N.2    Zambello, R.3
  • 31
    • 37849029903 scopus 로고    scopus 로고
    • Functional diversity of T-cell subpopulations in subacute and chronic hypersensitivity pneumonitis
    • Barrera L., Mendoza F., Zuniga J., et al. Functional diversity of T-cell subpopulations in subacute and chronic hypersensitivity pneumonitis. Am J Respir Crit Care Med 177 (2008) 44-55
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 44-55
    • Barrera, L.1    Mendoza, F.2    Zuniga, J.3
  • 32
    • 0036582288 scopus 로고    scopus 로고
    • Gammadelta T cells: functional plasticity and heterogeneity
    • Carding S.R., and Egan P.J. Gammadelta T cells: functional plasticity and heterogeneity. Nat Rev Immunol 2 (2002) 336-345
    • (2002) Nat Rev Immunol , vol.2 , pp. 336-345
    • Carding, S.R.1    Egan, P.J.2
  • 33
    • 0037363585 scopus 로고    scopus 로고
    • Immunoregulation in the tissues by gammadelta T cells
    • Hayday A., and Tigelaar R. Immunoregulation in the tissues by gammadelta T cells. Nat Rev Immunol 3 (2003) 233-242
    • (2003) Nat Rev Immunol , vol.3 , pp. 233-242
    • Hayday, A.1    Tigelaar, R.2
  • 34
    • 0028829424 scopus 로고
    • Direct presentation of nonpeptide prenyl pyrophosphate antigens to human gamma delta T cells
    • Morita C.T., Beckman E.M., Bukowski J.F., et al. Direct presentation of nonpeptide prenyl pyrophosphate antigens to human gamma delta T cells. Immunity 3 (1995) 495-507
    • (1995) Immunity , vol.3 , pp. 495-507
    • Morita, C.T.1    Beckman, E.M.2    Bukowski, J.F.3
  • 35
    • 0029073751 scopus 로고
    • Natural and synthetic non-peptide antigens recognized by human gamma delta T cells
    • Tanaka Y., Morita C.T., Tanaka Y., Nieves E., Brenner M.B., and Bloom B.R. Natural and synthetic non-peptide antigens recognized by human gamma delta T cells. Nature 375 (1995) 155-158
    • (1995) Nature , vol.375 , pp. 155-158
    • Tanaka, Y.1    Morita, C.T.2    Tanaka, Y.3    Nieves, E.4    Brenner, M.B.5    Bloom, B.R.6
  • 36
    • 0032513388 scopus 로고    scopus 로고
    • Recognition of stress-induced mhc molecules by intestinal epithelial gammadelta t cells
    • Groh V., Steinle A., Bauer S., and Spies T. Recognition of stress-induced mhc molecules by intestinal epithelial gammadelta t cells. Science 279 (1998) 1737-1740
    • (1998) Science , vol.279 , pp. 1737-1740
    • Groh, V.1    Steinle, A.2    Bauer, S.3    Spies, T.4
  • 37
    • 33846837461 scopus 로고    scopus 로고
    • Gammadelta t cells: firefighters or fire boosters in the front lines of inflammatory responses
    • Nanno M., Shiohara T., Yamamoto H., Kawakami K., and Ishikawa H. Gammadelta t cells: firefighters or fire boosters in the front lines of inflammatory responses. Immunol Rev 215 (2007) 103-113
    • (2007) Immunol Rev , vol.215 , pp. 103-113
    • Nanno, M.1    Shiohara, T.2    Yamamoto, H.3    Kawakami, K.4    Ishikawa, H.5
  • 38
    • 27644584691 scopus 로고    scopus 로고
    • Distribution and leukocyte contacts of gammadelta t cells in the lung
    • Wands J.M., Roark C.L., Aydintug M.K., et al. Distribution and leukocyte contacts of gammadelta t cells in the lung. J Leukoc Biol 78 (2005) 1086-1096
    • (2005) J Leukoc Biol , vol.78 , pp. 1086-1096
    • Wands, J.M.1    Roark, C.L.2    Aydintug, M.K.3
  • 39
    • 10744227223 scopus 로고    scopus 로고
    • Different potentials of gamma delta T cell subsets in regulating airway responsiveness: V gamma 1+ cells, but not v gamma 4+ cells, promote airway hyperreactivity, Th2 cytokines, and airway inflammation
    • Hahn Y.S., Taube C., Jin N., et al. Different potentials of gamma delta T cell subsets in regulating airway responsiveness: V gamma 1+ cells, but not v gamma 4+ cells, promote airway hyperreactivity, Th2 cytokines, and airway inflammation. J Immunol 172 (2004) 2894-2902
    • (2004) J Immunol , vol.172 , pp. 2894-2902
    • Hahn, Y.S.1    Taube, C.2    Jin, N.3
  • 40
    • 2942525398 scopus 로고    scopus 로고
    • Accumulation of gammadelta T cells in the lungs and their regulatory roles in Th1 response and host defense against pulmonary infection with cryptococcus neoformans
    • Uezu K., Kawakami K., Miyagi K., et al. Accumulation of gammadelta T cells in the lungs and their regulatory roles in Th1 response and host defense against pulmonary infection with cryptococcus neoformans. J Immunol 172 (2004) 7629-7634
    • (2004) J Immunol , vol.172 , pp. 7629-7634
    • Uezu, K.1    Kawakami, K.2    Miyagi, K.3
  • 41
    • 0036716775 scopus 로고    scopus 로고
    • Increased host resistance against pneumocystis carinii pneumonia in gammadelta T-cell-deficient mice: protective role of gamma interferon and CD8(+) T cells
    • Steele C., Zheng M., Young E., Marrero L., Shellito J.E., and Kolls J.K. Increased host resistance against pneumocystis carinii pneumonia in gammadelta T-cell-deficient mice: protective role of gamma interferon and CD8(+) T cells. Infect Immun 70 (2002) 5208-5215
    • (2002) Infect Immun , vol.70 , pp. 5208-5215
    • Steele, C.1    Zheng, M.2    Young, E.3    Marrero, L.4    Shellito, J.E.5    Kolls, J.K.6
  • 42
    • 33644780747 scopus 로고    scopus 로고
    • Gammadelta T cells regulate the early inflammatory response to bordetella pertussis infection in the murine respiratory tract
    • Zachariadis O., Cassidy J.P., Brady J., and Mahon B.P. Gammadelta T cells regulate the early inflammatory response to bordetella pertussis infection in the murine respiratory tract. Infect Immun 74 (2006) 1837-1845
    • (2006) Infect Immun , vol.74 , pp. 1837-1845
    • Zachariadis, O.1    Cassidy, J.P.2    Brady, J.3    Mahon, B.P.4
  • 43
    • 0034741430 scopus 로고    scopus 로고
    • Increase of gammadelta t lymphocytes in murine lungs occurs during recovery from pulmonary infection by nocardia asteroides
    • Tam S., King D.P., and Beaman B.L. Increase of gammadelta t lymphocytes in murine lungs occurs during recovery from pulmonary infection by nocardia asteroides. Infect Immun 69 (2001) 6165-6171
    • (2001) Infect Immun , vol.69 , pp. 6165-6171
    • Tam, S.1    King, D.P.2    Beaman, B.L.3
  • 44
    • 0033136629 scopus 로고    scopus 로고
    • Protective response to pulmonary injury requires gamma delta t lymphocytes
    • King D.P., Hyde D.M., Jackson K.A., et al. Protective response to pulmonary injury requires gamma delta t lymphocytes. J Immunol 162 (1999) 5033-5036
    • (1999) J Immunol , vol.162 , pp. 5033-5036
    • King, D.P.1    Hyde, D.M.2    Jackson, K.A.3
  • 45
    • 31944436620 scopus 로고    scopus 로고
    • Gene expression profiles distinguish idiopathic pulmonary fibrosis from hypersensitivity pneumonitis
    • Selman M., Pardo A., Barrera L., et al. Gene expression profiles distinguish idiopathic pulmonary fibrosis from hypersensitivity pneumonitis. Am J Respir Crit Care Med 173 (2006) 188-198
    • (2006) Am J Respir Crit Care Med , vol.173 , pp. 188-198
    • Selman, M.1    Pardo, A.2    Barrera, L.3
  • 46
    • 33847206969 scopus 로고    scopus 로고
    • Il-17 family cytokines and the expanding diversity of effector t cell lineages
    • Weaver C.T., Hatton R.D., Mangan P.R., and Harrington L.E. Il-17 family cytokines and the expanding diversity of effector t cell lineages. Annu Rev Immunol 25 (2007) 821-852
    • (2007) Annu Rev Immunol , vol.25 , pp. 821-852
    • Weaver, C.T.1    Hatton, R.D.2    Mangan, P.R.3    Harrington, L.E.4
  • 47
    • 33749318470 scopus 로고    scopus 로고
    • Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
    • Liang S.C., Tan X.Y., Luxenberg D.P., et al. Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J Exp Med 203 (2006) 2271-2279
    • (2006) J Exp Med , vol.203 , pp. 2271-2279
    • Liang, S.C.1    Tan, X.Y.2    Luxenberg, D.P.3
  • 48
    • 5644277476 scopus 로고    scopus 로고
    • Interleukin-17 family members and inflammation
    • Kolls J.K., and Linden A. Interleukin-17 family members and inflammation. Immunity 21 (2004) 467-476
    • (2004) Immunity , vol.21 , pp. 467-476
    • Kolls, J.K.1    Linden, A.2
  • 49
    • 33749138039 scopus 로고    scopus 로고
    • Il-17 production is dominated by gammadelta T cells rather than CD4 t cells during mycobacterium tuberculosis infection
    • Lockhart E., Green A.M., and Flynn J.L. Il-17 production is dominated by gammadelta T cells rather than CD4 t cells during mycobacterium tuberculosis infection. J Immunol 177 (2006) 4662-4669
    • (2006) J Immunol , vol.177 , pp. 4662-4669
    • Lockhart, E.1    Green, A.M.2    Flynn, J.L.3
  • 50
    • 23244432880 scopus 로고    scopus 로고
    • Long-term control of mycobacterium tuberculosis infection is mediated by dynamic immune responses
    • Lazarevic V., Nolt D., and Flynn J.L. Long-term control of mycobacterium tuberculosis infection is mediated by dynamic immune responses. J Immunol 175 (2005) 1107-1117
    • (2005) J Immunol , vol.175 , pp. 1107-1117
    • Lazarevic, V.1    Nolt, D.2    Flynn, J.L.3
  • 51
    • 0031067995 scopus 로고    scopus 로고
    • An anti-inflammatory role for gamma delta T lymphocytes in acquired immunity to mycobacterium tuberculosis
    • D'Souza C.D., Cooper A.M., Frank A.A., Mazzaccaro R.J., Bloom B.R., and Orme I.M. An anti-inflammatory role for gamma delta T lymphocytes in acquired immunity to mycobacterium tuberculosis. J Immunol 158 (1997) 1217-1221
    • (1997) J Immunol , vol.158 , pp. 1217-1221
    • D'Souza, C.D.1    Cooper, A.M.2    Frank, A.A.3    Mazzaccaro, R.J.4    Bloom, B.R.5    Orme, I.M.6
  • 52
    • 40049098958 scopus 로고    scopus 로고
    • Il-22 mediates mucosal host defense against gram-negative bacterial pneumonia
    • Aujla S.J., Chan Y.R., Zheng M., et al. Il-22 mediates mucosal host defense against gram-negative bacterial pneumonia. Nat Med 14 (2008) 275-281
    • (2008) Nat Med , vol.14 , pp. 275-281
    • Aujla, S.J.1    Chan, Y.R.2    Zheng, M.3
  • 53
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector th17 and regulatory T cells
    • Bettelli E., Carrier Y., Gao W., et al. Reciprocal developmental pathways for the generation of pathogenic effector th17 and regulatory T cells. Nature 441 (2006) 235-238
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3
  • 54
    • 33748588423 scopus 로고    scopus 로고
    • The orphan nuclear receptor rorgammat directs the differentiation program of proinflammatory IL-17 + T helper cells
    • Ivanov II, McKenzie B.S., Zhou L., et al. The orphan nuclear receptor rorgammat directs the differentiation program of proinflammatory IL-17 + T helper cells. Cell 126 (2006) 1121-1133
    • (2006) Cell , vol.126 , pp. 1121-1133
    • Ivanov II1    McKenzie, B.S.2    Zhou, L.3
  • 55
    • 33646560950 scopus 로고    scopus 로고
    • Transforming growth factor-beta induces development of the T(h)17 lineage
    • Mangan P.R., Harrington L.E., O'Quinn D.B., et al. Transforming growth factor-beta induces development of the T(h)17 lineage. Nature 441 (2006) 231-234
    • (2006) Nature , vol.441 , pp. 231-234
    • Mangan, P.R.1    Harrington, L.E.2    O'Quinn, D.B.3
  • 56
    • 32244442562 scopus 로고    scopus 로고
    • TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of il-17-producing t cells
    • Veldhoen M., Hocking R.J., Atkins C.J., Locksley R.M., and Stockinger B. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of il-17-producing t cells. Immunity 24 (2006) 179-189
    • (2006) Immunity , vol.24 , pp. 179-189
    • Veldhoen, M.1    Hocking, R.J.2    Atkins, C.J.3    Locksley, R.M.4    Stockinger, B.5
  • 57
    • 34548133583 scopus 로고    scopus 로고
    • Development, cytokine profile and function of human interleukin 17-producing helper T cells
    • Wilson N.J., Boniface K., Chan J.R., et al. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat Immunol 8 (2007) 950-957
    • (2007) Nat Immunol , vol.8 , pp. 950-957
    • Wilson, N.J.1    Boniface, K.2    Chan, J.R.3
  • 58
    • 38549159026 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of fibrosis
    • Wynn T.A. Cellular and molecular mechanisms of fibrosis. J Pathol 214 (2008) 199-210
    • (2008) J Pathol , vol.214 , pp. 199-210
    • Wynn, T.A.1
  • 59
    • 0026905242 scopus 로고
    • Transforming growth factor-beta is generated in the course of hypersensitivity pneumonitis: contribution to collagen synthesis
    • Denis M., and Ghadirian E. Transforming growth factor-beta is generated in the course of hypersensitivity pneumonitis: contribution to collagen synthesis. Am J Respir Cell Mol Biol 7 (1992) 156-160
    • (1992) Am J Respir Cell Mol Biol , vol.7 , pp. 156-160
    • Denis, M.1    Ghadirian, E.2


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