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Volumn 157, Issue 4, 2009, Pages 633-644

The role of the PDE4D cAMP phosphodiesterase in the regulation of glucagon-like peptide-1 release

Author keywords

CAMP; Dominant negative; Glucagon like peptide 1; GLUTag cells; H89; PDE4D4; Phosphodiesterase; Rolipram

Indexed keywords

CYCLIC AMP PHOSPHODIESTERASE; GLUCAGON LIKE PEPTIDE 1; ROLIPRAM; CYCLIC AMP; GLUCOSE; ISOENZYME; ISOQUINOLINE DERIVATIVE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PDE4D PROTEIN, RAT; PHOSPHODIESTERASE III; PROTEIN KINASE INHIBITOR; SULFONAMIDE;

EID: 70349898505     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2009.00194.x     Document Type: Article
Times cited : (47)

References (46)
  • 1
    • 0034020931 scopus 로고    scopus 로고
    • Effect of type-selective inhibitors on cyclic nucleotide phosphodiesterase activity and insulin secretion in the clonal insulin secreting cell line BRIN-BD11
    • Ahmad M, Abdel-Wahab Y, Tate R, Flatt P, Pyne N, Furman B (2000). Effect of type-selective inhibitors on cyclic nucleotide phosphodiesterase activity and insulin secretion in the clonal insulin secreting cell line BRIN-BD11. Br J Pharmacol 129: 1228-1234. (Pubitemid 30153980)
    • (2000) British Journal of Pharmacology , vol.129 , Issue.6 , pp. 1228-1234
    • Ahmad, M.1    Abdel-Wahab, Y.H.A.2    Tate, R.3    Flatt, P.R.4    Pyne, N.J.5    Furman, B.L.6
  • 2
    • 0037417890 scopus 로고    scopus 로고
    • Beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi
    • Baillie G, Sood A, McPhee I, Gall I, Perry S, Lefkowitz R et al. (2003). beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi. Proc Natl Acad Sci USA 100: 940-945.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 940-945
    • Baillie, G.1    Sood, A.2    McPhee, I.3    Gall, I.4    Perry, S.5    Lefkowitz, R.6
  • 3
    • 0036729478 scopus 로고    scopus 로고
    • Cyclic nucleotide research - Still expanding after half a century
    • Beavo JA, Brunton LL (2002). Cyclic nucleotide research - still expanding after half a century. Nat Rev Mol Cell Biol 3: 710-718.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 710-718
    • Beavo, J.A.1    Brunton, L.L.2
  • 5
    • 1542572127 scopus 로고    scopus 로고
    • The unique amino-terminal region of the PDE4D5 cAMP phosphodiesterase isoform confers preferential interaction with beta-arrestins
    • Bolger G, McCahill A, Huston E, Cheung Y, McSorley T, Baillie G et al. (2003). The unique amino-terminal region of the PDE4D5 cAMP phosphodiesterase isoform confers preferential interaction with beta-arrestins. J Biol Chem 278: 49230-49238.
    • (2003) J Biol Chem , vol.278 , pp. 49230-49238
    • Bolger, G.1    McCahill, A.2    Huston, E.3    Cheung, Y.4    McSorley, T.5    Baillie, G.6
  • 7
    • 0031765091 scopus 로고    scopus 로고
    • Regulation of glucagon-like peptide-1 synthesis and secretion in the GLUTag enteroendocrine cell line
    • Brubaker PL, Schloos J, Drucker DJ (1998). Regulation of glucagon-like peptide-1 synthesis and secretion in the GLUTag enteroendocrine cell line. Endocrinology 139: 4108-4114. (Pubitemid 28513695)
    • (1998) Endocrinology , vol.139 , Issue.10 , pp. 4108-4114
    • Brubaker, P.L.1    Schloos, J.2    Drucker, D.J.3
  • 10
    • 34447265905 scopus 로고    scopus 로고
    • Biochemistry and physiology of cyclic nucleotide phosphodiesterases: Essential components in cyclic nucleotide signaling
    • Conti M, Beavo JJ (2007). Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling. Annu Rev Biochem 76: 481-1451
    • (2007) Annu Rev Biochem , vol.76 , pp. 481-1451
    • Conti, M.1    Beavo, J.J.2
  • 11
    • 0037458648 scopus 로고    scopus 로고
    • Cyclic AMP-specific PDE4 phosphodiesterases as critical components of cyclic AMP signaling
    • DOI 10.1074/jbc.R200029200
    • Conti M, Richter W, Mehats C, Livera G, Park JY, Jin C (2003). Cyclic AMP-specific PDE4 phosphodiesterases as critical components of cyclic AMP signaling. J Biol Chem 278: 5493-5496. (Pubitemid 36800786)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.8 , pp. 5493-5496
    • Conti, M.1    Richter, W.2    Mehats, C.3    Livera, G.4    Park, J.-Y.5    Jin, C.6
  • 12
    • 0031732608 scopus 로고    scopus 로고
    • Glucagon-like-peptide-1 secretion from canine L-cells is increased by glucose-dependent-insulinotropic peptide but unaffected by glucose
    • Damholt A, Buchan A, Kofod H (1998). Glucagon-like-peptide-1 secretion from canine L-cells is increased by glucose-dependent-insulinotropic peptide but unaffected by glucose. Endocrinology 139: 2085-2091. (Pubitemid 28513872)
    • (1998) Endocrinology , vol.139 , Issue.4 , pp. 2085-2091
    • Damholt, A.B.1    Buchan, A.M.J.2    Kofod, H.3
  • 13
    • 4444278288 scopus 로고    scopus 로고
    • Milrinone efficiently potentiates insulin secretion induced by orally but not intravenously administered glucose in C57BL6J mice
    • DOI 10.1016/j.ejphar.2004.07.096, PII S0014299904008301
    • Degerman E, Manganiello V, Hoist JJ, Ahrén B (2004). Milrinone efficiently potentiates insulin secretion induced by orally but not intravenously administered glucose in C57BL6J mice. Eur J Pharmacol 498: 319-323. (Pubitemid 39208095)
    • (2004) European Journal of Pharmacology , vol.498 , Issue.1-3 , pp. 319-323
    • Degerman, E.1    Manganiello, V.2    Holst, J.J.3    Ahren, B.4
  • 14
    • 0028575660 scopus 로고
    • Activation of proglucagon gene transcription by protein kinase-A in a novel mouse enteroendocrine cell line
    • Drucker DJ, Jin T, Asa SL, Young TA, Brubaker PL (1994). Activation of proglucagon gene transcription by protein kinase-A in a novel mouse enteroendocrine cell line. Mol Endocrinol 8: 1646-1655.
    • (1994) Mol Endocrinol , vol.8 , pp. 1646-1655
    • Drucker, D.J.1    Jin, T.2    Asa, S.L.3    Young, T.A.4    Brubaker, P.L.5
  • 16
    • 0032005005 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
    • Flint A, Raben A, Astrup A, Holst JJ (1998). Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans. J Clin Invest 101: 515-520. (Pubitemid 28084232)
    • (1998) Journal of Clinical Investigation , vol.101 , Issue.3 , pp. 515-520
    • Flint, A.1    Raben, A.2    Astrup, A.3    Holst, J.J.4
  • 17
    • 33750314863 scopus 로고    scopus 로고
    • Modulation of cyclic nucleotides and cyclic nucleotide phosphodiesterases in pancreatic islet β-cells and intestinal L-cells as targets for treating diabetes mellitus
    • Furman B, Pyne N (2006). Modulation of cyclic nucleotides and cyclic nucleotide phosphodiesterases in pancreatic islet beta-cells and intestinal L-cells as targets for treating diabetes mellitus. Curr Opin Investig Drugs 7: 898-905. (Pubitemid 44613717)
    • (2006) Current Opinion in Investigational Drugs , vol.7 , Issue.10 , pp. 898-905
    • Furman, B.1    Pyne, N.2
  • 18
    • 0141532690 scopus 로고    scopus 로고
    • A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from the GLUTag cell line
    • DOI 10.2337/diabetes.52.5.1147
    • Gribble FM, Williams L, Simpson AK, Reimann F (2003). A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from the GLUTag cell line. Diabetes 52: 1147-1154. (Pubitemid 36523349)
    • (2003) Diabetes , vol.52 , Issue.5 , pp. 1147-1154
    • Gribble, F.M.1    Williams, L.2    Simpson, A.K.3    Reimann, F.4
  • 19
    • 0037020258 scopus 로고    scopus 로고
    • Important role of phosphodiesterase 3B for the stimulatory action of cAMP on pancreatic beta-cell exocytosis and release of Insulin
    • Härndahl L, Jing X, Ivarsson R, Degerman E, Ahrén B, Manganiello V et al. (2002). Important role of phosphodiesterase 3B for the stimulatory action of cAMP on pancreatic beta-cell exocytosis and release of Insulin. J Biol Chem 277: 37446-37455.
    • (2002) J Biol Chem , vol.277 , pp. 37446-37455
    • Härndahl, L.1    Jing, X.2    Ivarsson, R.3    Degerman, E.4    Ahrén, B.5    Manganiello, V.6
  • 21
    • 0026645809 scopus 로고
    • Signal transduction crosstalk in the endocrine system: Pancreatic beta-cells and the glucose competence concept
    • Holz GG, Habener JF (1992). Signal transduction crosstalk in the endocrine system: pancreatic beta-cells and the glucose competence concept. Trends Biochem Sci 17: 388-393.
    • (1992) Trends Biochem Sci , vol.17 , pp. 388-393
    • Holz, G.G.1    Habener, J.F.2
  • 22
    • 0037443097 scopus 로고    scopus 로고
    • PDE4 cAMP phosphodiesterases: Modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization
    • Houslay MD, Adams DR (2003). PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization. Biochem J 370: 1-18.
    • (2003) Biochem J , vol.370 , pp. 1-18
    • Houslay, M.D.1    Adams, D.R.2
  • 23
    • 34247105883 scopus 로고    scopus 로고
    • CAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: A molecular toolbox for generating compartmentalized cAMP signaling
    • Houslay MD, Baillie GS, Maurice DH (2007). cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling. Circ Res 100: 950-966.
    • (2007) Circ Res , vol.100 , pp. 950-966
    • Houslay, M.D.1    Baillie, G.S.2    Maurice, D.H.3
  • 26
    • 58249117850 scopus 로고    scopus 로고
    • Epac is involved in cAMP-stimulated proglucagon expression and hormone production, but not hormone secretion in pancreatic alpha and intestinal L cell lines
    • Islam D, Zhang N, Wang P, Li H, Brubaker PL, Gaisano H et al. (2009). Epac is involved in cAMP-stimulated proglucagon expression and hormone production, but not hormone secretion in pancreatic alpha and intestinal L cell lines. Am J Physiol Endocrinol Metab 296: E174-E181.
    • (2009) Am J Physiol Endocrinol Metab , vol.296
    • Islam, D.1    Zhang, N.2    Wang, P.3    Li, H.4    Brubaker, P.L.5    Gaisano, H.6
  • 27
    • 0031728690 scopus 로고    scopus 로고
    • Ancient gene duplication and domain shuffling in the animal cyclic nucleotide phosphodiesterase family
    • DOI 10.1016/S0014-5793(98)01150-8, PII S0014579398011508
    • Koyanagi M, Suga H, Hoshiyama D, Ono K, Iwabe N, Kuma K et al. (1998). Ancient gene duplication and domain shuffling in the animal cyclic nucleotide phosphodiesterase family. FEBS Lett 436: 323-328. (Pubitemid 28482954)
    • (1998) FEBS Letters , vol.436 , Issue.3 , pp. 323-328
    • Koyanagi, M.1    Suga, H.2    Hoshiyama, D.3    Ono, K.4    Iwabe, N.5    Kuma, K.-I.6    Miyata, T.7
  • 28
    • 0031737058 scopus 로고    scopus 로고
    • Expression of cyclic GMP-inbibited phosphodiesterases 3A and 3B (PDE3A and PDE3B) in rat tissues: Differential subcellular localization and regulated expression by cyclic AMP
    • Liu H, Maurice DH (1998). Expression of cyclic GMP-inhibited phosphodiesterases 3A and 3B (PDE3A and PDE3B) in rat tissues: differential subcellular localization and regulated expression by cyclic. AMP Br J Pharmacol 125: 1501-1510. (Pubitemid 28548563)
    • (1998) British Journal of Pharmacology , vol.125 , Issue.7 , pp. 1501-1510
    • Liu, H.1    Maurice, D.H.2
  • 29
    • 33746076698 scopus 로고    scopus 로고
    • Role of the exchange protein directly activated by cyclic adenosine 5′-monophosphate (Epac) pathway in regulating proglucagon gene expression in intestinal endocrine L cells
    • DOI 10.1210/en.2006-0056
    • Lotfi S, Li Z, Sun J, Zuo Y, Lam P, Kang Y et al. (2006). Role of the exchange protein directly activated by cyclic adenosine 5′-monophosphate (Epac) pathway in regulating proglucagon gene expression in intestinal endocrine L cells. Endocrinology 147: 3727-3736. (Pubitemid 44079377)
    • (2006) Endocrinology , vol.147 , Issue.8 , pp. 3727-3736
    • Lotfi, S.1    Li, Z.2    Sun, J.3    Zuo, Y.4    Lam, P.P.L.5    Kang, Y.6    Rahimi, M.7    Islam, D.8    Wang, P.9    Gaisano, H.Y.10    Jin, T.11
  • 30
    • 31144433061 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents
    • Lugnier C (2006). Cyclic nucleotide phosphodiesterase (PDE) superfamily: a new target for the development of specific therapeutic agents. Pharmacol Ther 109: 366-398.
    • (2006) Pharmacol Ther , vol.109 , pp. 366-398
    • Lugnier, C.1
  • 31
    • 23944494162 scopus 로고    scopus 로고
    • 2-adrenergic receptor to activation of ERK in HEK293B2 cells
    • DOI 10.1074/jbc.M414316200
    • Lynch MJ, Baillie GS, Mohamed A, Li X, Maisonneuve C, Klussmann E et al. (2005). RNA silencing identifies PDE4D5 as the functionally relevant cAMP phosphodiesterase interacting with beta arrestin to control the protein kinase A/AKAP79-mediated switching of the beta2-adrenergic receptor to activation of ERK in HEK293B2 cells. J Biol Chem 280: 33178-33189. (Pubitemid 41397113)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.39 , pp. 33178-33189
    • Lynch, M.J.1    Baillie, G.S.2    Mohamed, A.3    Li, X.4    Maisonneuve, C.5    Klussmann, E.6    Van, H.G.7    Houslay, M.D.8
  • 32
    • 21644449363 scopus 로고    scopus 로고
    • In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region
    • DOI 10.1016/j.cellsig.2005.04.003, PII S0898656805000835
    • McCahill A, McSorely T, Huston E, Hill EV, Lynch MJ, Gall I et al. (2005). In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAPtethered protein kinase A type II located in the centrosomal region. Cell Signal 17: 1158-1173. (Pubitemid 40933535)
    • (2005) Cellular Signalling , vol.17 , Issue.9 , pp. 1158-1173
    • McCahill, A.1    McSorley, T.2    Huston, E.3    Hill, E.V.4    Lynch, M.J.5    Gall, I.6    Keryer, G.7    Lygren, B.8    Tasken, K.9    Van, H.G.10    Houslay, M.D.11
  • 33
    • 0030667056 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans
    • Nauck MA, Niedereichholz U, Ettler R, Holst JJ, Orskov C, Ritzel R et al. (1997). Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans. Am J Physiol 273: E981-E988.
    • (1997) Am J Physiol , vol.273
    • Nauck, M.A.1    Niedereichholz, U.2    Ettler, R.3    Holst, J.J.4    Orskov, C.5    Ritzel, R.6
  • 34
    • 40349114501 scopus 로고    scopus 로고
    • GPR119, a novel G protein-coupled receptor target for the treatment of type 2 diabetes and obesity
    • DOI 10.1038/sj.bjp.0707529, PII 0707529
    • Overton HA, Fyfe MC, Reynet C (2008). GPR119, a novel G proteincoupled receptor target for the treatment of type 2 diabetes and obesity. Br J Pharmacol 153 (Suppl. 1): S76-S81. (Pubitemid 351340991)
    • (2008) British Journal of Pharmacology , vol.153 , Issue.SUPPL. 1
    • Overton, H.A.1    Fyfe, M.C.T.2    Reynet, C.3
  • 35
    • 0141594650 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterases in pancreatic islets
    • DOI 10.1007/s00125-003-1176-7
    • Pyne N, Furman B (2003). Cyclic nucleotide phosphodiesterases in pancreatic islets. Diabetologia 46: 1179-1189. (Pubitemid 37214975)
    • (2003) Diabetologia , vol.46 , Issue.9 , pp. 1179-1189
    • Pyne, N.J.1    Furman, B.L.2
  • 36
    • 0036724256 scopus 로고    scopus 로고
    • Glucose-sensing in glucagon-like peptide-1-secreting cells
    • Reimann F, Gribble FM (2002). Glucose-sensing in glucagon-like peptide-1-secreting cells. Diabetes 51: 2757-2763.
    • (2002) Diabetes , vol.51 , pp. 2757-2763
    • Reimann, F.1    Gribble, F.M.2
  • 37
    • 33845544947 scopus 로고    scopus 로고
    • Signaling mechanisms underlying the release of glucagon-like peptide 1
    • DOI 10.2337/db06-S010
    • Reimann F, Ward PS, Gribble FM (2006). Signalling mechanisms underlying the release of glucagon-like peptide 1. Diabetes 55: S78-S85. (Pubitemid 44927036)
    • (2006) Diabetes , vol.55 , Issue.SUPPL. 2
    • Reimann, F.1    Ward, P.S.2    Gribble, F.M.3
  • 40
    • 51849099001 scopus 로고    scopus 로고
    • Discovery of the first potent and orally efficacious agonist of the orphan G-protein coupled receptor 119
    • Semple G, Fioravanti B, Pereira G, Calderón I, Uy J, Choi K et al. (2008). Discovery of the first potent and orally efficacious agonist of the orphan G-protein coupled receptor 119. J Med Chem 51: 5172-5175.
    • (2008) J Med Chem , vol.51 , pp. 5172-5175
    • Semple, G.1    Fioravanti, B.2    Pereira, G.3    Calderón, I.4    Uy, J.5    Choi, K.6
  • 41
    • 0029122198 scopus 로고
    • Effects of type-selective phosphodiesterase inhibitors on glucose-induced insulin secretion and islet phosphodiesterase activity
    • Shafiee-Nick R, Pyne NJ, Furman B (1995). Effects of type-selective phosphodiesterase inhibitors on glucose-induced insulin secretion and islet phosphodiesterase activity. Br J Pharmacol 115:1486-1492.
    • (1995) Br J Pharmacol , vol.115 , pp. 1486-1492
    • Shafiee-Nick, R.1    Pyne, N.J.2    Furman, B.3
  • 42
    • 34548487959 scopus 로고    scopus 로고
    • Cyclic AMP triggers glucagon-like peptide-1 secretion from the GLUTag enteroendocrine cell line
    • DOI 10.1007/s00125-007-0750-9
    • Simpson A, Ward P, Wong K, Collord G, Habib A, Reimann F et al. (2007). Cyclic AMP triggers glucagon-like peptide-1 secretion from the GLUTag enteroendocrine cell line. Diabetologia 50: 2181-2189. (Pubitemid 47373843)
    • (2007) Diabetologia , vol.50 , Issue.10 , pp. 2181-2189
    • Simpson, A.K.1    Ward, P.S.2    Wong, K.Y.3    Collord, G.J.4    Habib, A.M.5    Reimann, F.6    Gribble, F.M.7
  • 43
    • 0015231739 scopus 로고
    • Multiple cyclic nucleotide phosphodiesterase activities from rat brain
    • Thompson WJ, Appleman MM (1971). Multiple cyclic nucleotide phosphodiesterase activities from rat brain. Biochemistry 10: 311-316.
    • (1971) Biochemistry , vol.10 , pp. 311-316
    • Thompson, W.J.1    Appleman, M.M.2
  • 45
    • 0033591233 scopus 로고    scopus 로고
    • The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform
    • Yarwood S, Steele M, Scotland G, Houslay M, Bolger G (1999). The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform. J Biol Chem 274: 14909-14917. (Pubitemid 129518822)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.21 , pp. 14909-14917
    • Yarwood, S.J.1    Steele, M.R.2    Scotland, G.3    Houslay, M.D.4    Bolger, G.B.5


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