PSEN1 polymorphisms alter the rate of cognitive decline in sporadic Alzheimer's disease patients

Neurobiology of Aging

Volumn 30, Issue 12, 2009, Pages 1992-1999

  Belbin, Olivia ^a   Beaumont, Helen ^b   Warden, Donald ^b   Smith, A David ^b   Kalsheker, Noor ^a   Morgan, Kevin ^a  

^a QUEEN S MEDICAL CENTRE   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Alzheimer's disease; Cognitive decline; Presenilin 1; Single nucleotide polymorphisms

Indexed keywords

PRESENILIN 1;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MENTAL PERFORMANCE; PHENOTYPE; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

AGE OF ONSET; AGED; ALZHEIMER DISEASE; CASE-CONTROL STUDIES; COGNITION DISORDERS; DISEASE PROGRESSION; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MODELS, GENETIC; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PRESENILIN-1; PSYCHIATRIC STATUS RATING SCALES; TIME FACTORS;

EID: 70349866521     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2008.02.013     Document Type: Article

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