Increasing the selectivity of amikacin in rat peritoneal macrophages using carrier erythrocytes

European Journal of Pharmaceutical Sciences

Volumn 38, Issue 4, 2009, Pages 320-324

  Briones, Elsa ^a   Colino, Clara Isabel ^a   Millán, Carmen G ^a   Lanao, José M ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

Amikacin; Biodistribution; Carrier erythrocytes; Macrophages; Pharmacokinetics

Indexed keywords

AMIKACIN; DRUG CARRIER; SODIUM CHLORIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOENGINEERING; CONTROLLED STUDY; DIALYSIS; DRUG ACCUMULATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG SELECTIVITY; DRUG TISSUE LEVEL; DRUG UPTAKE; ERYTHROCYTE; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CORTEX; KIDNEY MEDULLA; LIVER; LUNG; MALE; MONOLAYER CULTURE; NONHUMAN; PARTITION COEFFICIENT; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; RAT; SPLEEN; TISSUE DISTRIBUTION;

AMIKACIN; ANIMALS; DRUG CARRIERS; ERYTHROCYTES; MACROPHAGES, PERITONEAL; MALE; RATS; RATS, WISTAR; TISSUE DISTRIBUTION;

EID: 70349835152     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2009.08.003     Document Type: Article

References (30)

1. Ahsan F., Rivas I.P., Khan M.A., and Torres Suárez A.I. Targeting to macrophages: role of physicochemical properties of particulate carriers-liposomes and microspheres-on the phagocytosis by macrophages. J. Control. Release 79 (2002) 29-40
2. Alvarez F.J., Jordán J.A., Herráez A., Díez J.C., and Tejedor M.C. Hypotonically loaded rat erythrocytes deliver encapsulated substances into peritoneal macrophages. J. Biochem. 123 (1998) 233-239
3. Barcia-Macay M., Seral C., Mingeot-Leclercq M.P., Tulkens P.M., and Van Bambeke F. Pharmacodynamic evaluation of the intracellular activities of antibiotics against Staphylococcus aureus in a model of THP-1 macrophages. Antimicrob. Agents Chemother. 50 (2006) 841-851
4. Bender A.R., von Briesen H., Kreuter J., Duncan I.B., and Rubsamen-Waigmann H. Efficiency of nanoparticles as a carrier system for antiviral agents in human immunodeficiency virus-infected human monocytes/macrophages in vitro. Antimicrob. Agents Chemother. 40 (1996) 1467-1471
5. Berman J.D., and Gallalee J.V. Antileishmanial activity of human red blood cells containing formycin A. J. Infect. Dis. 151 (1985) 698
6. Briones E., Colino C.I., and Lanao J.M. Delivery systems to increase the selectivity of antibiotics in phagocytic cells. J. Control. Release 125 (2008) 210-227
7. Carryn S., Chanteux H., Seral C., Mingeot-Leclercq M.P., Van Bambeke F., and Tulkens P.M. Intracellular pharmacodynamics of antibiotics. Infect. Dis. Clin. N. Am. 17 (2003) 615-634
8. DeLoach J.R. Encapsulation potential of a trypanocidal drug homidium bromide in bovine carrier erythrocytes. Res. Exp. Med. 185 (1985) 345-353
9. DeLoach J.R., and Wagner G.G. Pharmacokinetics of tetracycline encapsulated in bovine carrier erythrocytes. Am. J. Vet. Res. 45 (1984) 640-642
10. Eichler H.G., Rameis H., Bauer K., Korn A., Bacher S., and Gasic S. Survival of gentamicin-loaded carrier erythrocytes in healthy human volunteers. Eur. J. Clin. Invest. 16 (1986) 39-42
11. Ernst J.D., and Stendahl O. Phagocytosis of Bacteria and Bacterial Pathogenicity (2006), Cambridge University Press, Cambridge
12. Gutiérrez C., Castañeda A.Z., López F.G., Marinero M.L., Lanao J.M., and Arévalo M. Encapsulation and in vitro evaluation of amikacin-loaded erythrocytes. Drug Deliv. 12 (2005) 409-416
13. Gutiérrez C., Marinero M.L., Castañeda A.Z., and Lanao J.M. Drug, enzyme and peptide delivery using erythrocytes as carriers. J. Control. Release 95 (2004) 27-49
14. Gutiérrez C., Zarzuelo A., González F., Sayalero M.L., and Lanao J.M. Pharmacokinetics and biodistribution of amikacin encapsulated in carrier erythrocytes. J. Antimicrob. Chemother. 61 (2008) 375-381
15. Gutiérrez C., Zarzuelo A., Sayalero M.L., and Lanao J.M. Factors associated with the performance of carrier erythrocytes obtained by hypotonic dialysis. Blood Cells Mol. Dis. 33 2 (2004) 132-140
16. Holmes B., Quie P.G., Windhorst D.B., Pollara B., and Good R.A. Protection of phagocytized bacteria from the killing action of antibiotics. Nature 210 (1966) 1131-1132
17. Karlowsky J.A., and Zhanel G.G. Concepts on the use of liposomal antimicrobial agents: applications for aminoglycosides. Clin. Infect. Dis. 15 (1992) 654-667
18. Klempner M.S. White cells. In: Ristuccia A.M., and Cunha B.A. (Eds). Antimicrobial Therapy (1984), Raven Press, New York 513-517
19. Lanao J.M., and Sayalero M.L. Cells and cell ghosts as drug carriers. In: Torchilin V.P. (Ed). Nanoparticulates as Drug Carriers (2006), Imperial College Press, London 329-348
20. Lanao J.M., Briones E., and Colino C.I. Recent advances in delivery systems for anti-HIV1 therapy. J. Drug Target. 15 (2007) 21-36
21. Lutwyche P., Cordeiro C., Wiseman D.J., St-Louis M., Uh M., Hope M.J., Webb M.S., and Finlay B.B. Intracellular delivery and antibacterial activity of gentamicin encapsulated in pH-sensitive liposomes. Antimicrob. Agents Chemother. 42 (1998) 2511-2520
22. Magnani M., Rossi L., Fraternale A., Bianchi M., Antonelli A., Crinelli R., and Chiarantini L. Erythrocyte-mediated delivery of drugs, peptides and modified oligonucleotides. Gene Ther. 9 (2002) 749-751
23. Maurin M., and Raoult D. Use of aminoglycosides in treatment of infections due to intracellular bacteria. Antimicrob. Agents Chemother. 45 (2001) 2977-2986
24. Mishra P.R., Jain S., and Jain N.K. Engineered human erythrocytes as carriers for ciprofloxacin. Drug Deliv. 3 (1996) 239-244
25. Prokesch R.C., and Hand W.L. Antibiotic entry into human polymorphonuclear leukocytes. Antimicrob. Agents Chemother. 21 (1982) 373-380
26. Reinoso R.F., Lanao J.M., Lorente F., López F.G., and Domínguez-Gil A. Uptake of antibiotics by phagocytic cells: study methods and therapeutic implications. Rev. Esp. Quimioterap. 8 (1995) 100-108
27. Santos B., Sayalero M.L., Zarzuelo A., and Lanao J.M. Determination of amikacin in biological tissues by HPLC. J. Liq. Chrom. Rel. Technol. 25 (2002) 463-473
28. Schiffelers R., Storm G., and Bakker-Woudenberg I. Liposome-encapsulated aminoglycosides in pre-clinical and clinical studies. J. Antimicrob. Chemother. 48 (2001) 333-344
29. Weiss M. On pharmacokinetics in target tissues. Biopharm. Drug. Dispos. 6 (1985) 37-66
30. Weitzman E.A. Analyzing qualitative data with computer software. Health Serv. Res. 34 (1999) 1241-1263