메뉴 건너뛰기




Volumn 215, Issue 1-2, 2009, Pages 108-116

Effects of interferon-beta therapy on innate and adaptive immune responses to the human endogenous retroviruses HERV-H and HERV-W, cytokine production, and the lectin complement activation pathway in multiple sclerosis

Author keywords

Complement activation; Cytokines; HERV H; HERV W; Interferon beta; Multiple sclerosis

Indexed keywords

BETA INTERFERON; BETA1A INTERFERON; BIOLOGICAL MARKER; CYTOKINE; INTERFERON BETA SERINE; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; MANNAN BINDING LECTIN; MANNAN BINDING LECTIN ASSOCIATED SERINE PROTEINASE; TUMOR NECROSIS FACTOR ALPHA;

EID: 70349813785     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2009.08.015     Document Type: Article
Times cited : (31)

References (59)
  • 2
    • 0033870194 scopus 로고    scopus 로고
    • HTLV-1 infections
    • Bangham C. HTLV-1 infections. J. Clin. Pathol. 53 (2000) 581-586
    • (2000) J. Clin. Pathol. , vol.53 , pp. 581-586
    • Bangham, C.1
  • 3
    • 1642281535 scopus 로고    scopus 로고
    • Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion
    • Barnett M.H., and Prineas J.W. Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion. Ann. Neurol. 55 (2004) 458-468
    • (2004) Ann. Neurol. , vol.55 , pp. 458-468
    • Barnett, M.H.1    Prineas, J.W.2
  • 5
    • 34447107948 scopus 로고    scopus 로고
    • Multiple sclerosis: disease biomarkers as indicated by pathophysiology
    • Berger T., and Reindl M. Multiple sclerosis: disease biomarkers as indicated by pathophysiology. J. Neurol. Sci. 259 (2007) 21-26
    • (2007) J. Neurol. Sci. , vol.259 , pp. 21-26
    • Berger, T.1    Reindl, M.2
  • 6
    • 0344450781 scopus 로고    scopus 로고
    • Molecular characterization and placental expression of HERV-W, a new human endogenous retrovirus family
    • Blond J.L., Beseme F., Duret L., Bouton O., Bedin F., Perron H., Mandrand B., and Mallet F. Molecular characterization and placental expression of HERV-W, a new human endogenous retrovirus family. J. Virol. 73 (1999) 1175-1185
    • (1999) J. Virol. , vol.73 , pp. 1175-1185
    • Blond, J.L.1    Beseme, F.2    Duret, L.3    Bouton, O.4    Bedin, F.5    Perron, H.6    Mandrand, B.7    Mallet, F.8
  • 9
    • 18744409058 scopus 로고    scopus 로고
    • Association of human endogenous retroviruses with multiple sclerosis and possible interactions with herpes viruses
    • Christensen T. Association of human endogenous retroviruses with multiple sclerosis and possible interactions with herpes viruses. Rev. Med. Virol. 15 (2005) 179-211
    • (2005) Rev. Med. Virol. , vol.15 , pp. 179-211
    • Christensen, T.1
  • 10
    • 70349819920 scopus 로고    scopus 로고
    • Retroviruses in autoimmunity
    • Pandalai S.G. (Ed), Research Signpost, Kerala
    • Christensen T. Retroviruses in autoimmunity. In: Pandalai S.G. (Ed). Recent Research Developments in Immunology vol. 7 (2006), Research Signpost, Kerala 25-43
    • (2006) Recent Research Developments in Immunology , vol.7 , pp. 25-43
    • Christensen, T.1
  • 12
    • 0037330508 scopus 로고    scopus 로고
    • Antibodies against a human endogenous retrovirus and the preponderance of env splice variants in multiple sclerosis patients
    • Christensen T., Dissing Sørensen P., Hansen H.J., and Møller-Larsen A. Antibodies against a human endogenous retrovirus and the preponderance of env splice variants in multiple sclerosis patients. Mult. Scler. 9 (2003) 6-15
    • (2003) Mult. Scler. , vol.9 , pp. 6-15
    • Christensen, T.1    Dissing Sørensen, P.2    Hansen, H.J.3    Møller-Larsen, A.4
  • 13
    • 33846799225 scopus 로고    scopus 로고
    • Gene-environment interactions in multiple sclerosis: innate and adaptive immune responses to human endogenous retrovirus and herpes virus antigens and the lectin complement activation pathway
    • Christensen T., Petersen T., Thiel S., Brudek T., Ellermann-Eriksen E., and Møller-Larsen A. Gene-environment interactions in multiple sclerosis: innate and adaptive immune responses to human endogenous retrovirus and herpes virus antigens and the lectin complement activation pathway. J. Neuroimmunol. 183 (2007) 175-188
    • (2007) J. Neuroimmunol. , vol.183 , pp. 175-188
    • Christensen, T.1    Petersen, T.2    Thiel, S.3    Brudek, T.4    Ellermann-Eriksen, E.5    Møller-Larsen, A.6
  • 17
    • 0141856317 scopus 로고    scopus 로고
    • Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins
    • de Parseval N., Lazar V., Casella J.F., Benit L., and Heidmann T. Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins. J. Virol. 77 (2003) 10414-10422
    • (2003) J. Virol. , vol.77 , pp. 10414-10422
    • de Parseval, N.1    Lazar, V.2    Casella, J.F.3    Benit, L.4    Heidmann, T.5
  • 19
    • 27444448187 scopus 로고    scopus 로고
    • MRI evidence for multiple sclerosis as a diffuse disease of the central nervous system
    • Filippi M., and Rocca M.A. MRI evidence for multiple sclerosis as a diffuse disease of the central nervous system. J. Neurol. 252 S5 (2005) 16-24
    • (2005) J. Neurol. , vol.252 , Issue.SUPPL.5 , pp. 16-24
    • Filippi, M.1    Rocca, M.A.2
  • 20
    • 0033858845 scopus 로고    scopus 로고
    • Effect of interferon beta on human myelin basic protein-specific T-cell lines: comparison of IFNbeta-1a and IFNbeta-1b
    • Francis G., Weber F., and Rieckmann P. Effect of interferon beta on human myelin basic protein-specific T-cell lines: comparison of IFNbeta-1a and IFNbeta-1b. Neurology 55 (2000) 322-323
    • (2000) Neurology , vol.55 , pp. 322-323
    • Francis, G.1    Weber, F.2    Rieckmann, P.3
  • 21
    • 33750621975 scopus 로고    scopus 로고
    • Simultaneous quantification of 17 immune mediators in aqueous humour from patients with corneal rejection
    • Funding M., Hansen T.K., Gjedsted J., and Ehlers N. Simultaneous quantification of 17 immune mediators in aqueous humour from patients with corneal rejection. Acta Ophthalmol. Scand. 84 (2006) 759-765
    • (2006) Acta Ophthalmol. Scand. , vol.84 , pp. 759-765
    • Funding, M.1    Hansen, T.K.2    Gjedsted, J.3    Ehlers, N.4
  • 22
    • 2142662186 scopus 로고    scopus 로고
    • Multiple sclerosis
    • Hafler D. Multiple sclerosis. J. Clin. Invest. 113 (2004) 788-794
    • (2004) J. Clin. Invest. , vol.113 , pp. 788-794
    • Hafler, D.1
  • 23
    • 33947681258 scopus 로고    scopus 로고
    • Cytokine changes during interferon-beta therapy in multiple sclerosis: correlations with interferon dose and MRI response
    • Graber J.J., Ford D., Zhan M., Francis G., Panitch H., and Dhib-Jalbut S. Cytokine changes during interferon-beta therapy in multiple sclerosis: correlations with interferon dose and MRI response. J. Neuroimmunol. 185 (2007) 168-174
    • (2007) J. Neuroimmunol. , vol.185 , pp. 168-174
    • Graber, J.J.1    Ford, D.2    Zhan, M.3    Francis, G.4    Panitch, H.5    Dhib-Jalbut, S.6
  • 25
    • 0030989875 scopus 로고    scopus 로고
    • Biotechnological agents for the immunotherapy of multiple sclerosis. Principles, problems and perspectives
    • Hohlfeld R. Biotechnological agents for the immunotherapy of multiple sclerosis. Principles, problems and perspectives. Brain 120 (1997) 865-916
    • (1997) Brain , vol.120 , pp. 865-916
    • Hohlfeld, R.1
  • 26
    • 0041534400 scopus 로고    scopus 로고
    • Collectins and ficolins: humoral lectins of the innate immune defense
    • Holmskov U., Thiel S., and Jensenius J.C. Collectins and ficolins: humoral lectins of the innate immune defense. Annu. Rev. Immunol. 21 (2003) 547-578
    • (2003) Annu. Rev. Immunol. , vol.21 , pp. 547-578
    • Holmskov, U.1    Thiel, S.2    Jensenius, J.C.3
  • 27
    • 0028723892 scopus 로고
    • A brief history of the use of interferons as treatment of multiple sclerosis
    • Jacobs L., and Johnson K.P. A brief history of the use of interferons as treatment of multiple sclerosis. Arch. Neurol. 51 (1994) 1245-1252
    • (1994) Arch. Neurol. , vol.51 , pp. 1245-1252
    • Jacobs, L.1    Johnson, K.P.2
  • 29
    • 0041589180 scopus 로고    scopus 로고
    • Neuropathology of multiple sclerosis - new concepts
    • Kornek B., and Lassmann H. Neuropathology of multiple sclerosis - new concepts. Brain Res. Bull. 6 (2003) 321-326
    • (2003) Brain Res. Bull. , vol.6 , pp. 321-326
    • Kornek, B.1    Lassmann, H.2
  • 31
    • 0021035886 scopus 로고
    • Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS)
    • Kurtzke J.F. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 33 (1983) 1444-1452
    • (1983) Neurology , vol.33 , pp. 1444-1452
    • Kurtzke, J.F.1
  • 32
    • 0035096330 scopus 로고    scopus 로고
    • Heterogeneity of multiple sclerosis pathogenesis: implications for diagnosis and therapy
    • Lassmann H., Bruck W., and Lucchinetti C. Heterogeneity of multiple sclerosis pathogenesis: implications for diagnosis and therapy. Trends Mol. Med. 7 (2001) 115-121
    • (2001) Trends Mol. Med. , vol.7 , pp. 115-121
    • Lassmann, H.1    Bruck, W.2    Lucchinetti, C.3
  • 33
    • 0033526516 scopus 로고    scopus 로고
    • Isolation of a human endogenous retroviral HERV-H element with an open env reading frame
    • Lindeskog M., Mager D.L., and Blomberg J. Isolation of a human endogenous retroviral HERV-H element with an open env reading frame. Virology 258 (1999) 441-450
    • (1999) Virology , vol.258 , pp. 441-450
    • Lindeskog, M.1    Mager, D.L.2    Blomberg, J.3
  • 36
    • 79958830026 scopus 로고    scopus 로고
    • MBL polymorphisms and infectious diseases
    • Vasta G.R., and Ahmed H. (Eds), CRC Press, Boca Raton, FL Chapter 22
    • Moller-Kristensen M., Thiel S., and Jensenius J.C. MBL polymorphisms and infectious diseases. In: Vasta G.R., and Ahmed H. (Eds). Animal Lectins, a Functional View (2007), CRC Press, Boca Raton, FL Chapter 22
    • (2007) Animal Lectins, a Functional View
    • Moller-Kristensen, M.1    Thiel, S.2    Jensenius, J.C.3
  • 37
    • 0033923618 scopus 로고    scopus 로고
    • Short-term treatment of relapsing remitting multiple sclerosis patients with interferon (IFN)-beta1B transiently increases the blood levels of interleukin (IL)-6, IL-10 and IFN-gamma without significantly modifying those of IL-1beta, IL-2, IL-4 and tumour necrosis factor-alpha
    • Nicoletti F., Di Marco R., Patti F., Zaccone P., L'Episcopo M.R., Reggio E., Xiang M., Nicoletti A., and Reggio A. Short-term treatment of relapsing remitting multiple sclerosis patients with interferon (IFN)-beta1B transiently increases the blood levels of interleukin (IL)-6, IL-10 and IFN-gamma without significantly modifying those of IL-1beta, IL-2, IL-4 and tumour necrosis factor-alpha. Cytokine 12 (2000) 682-687
    • (2000) Cytokine , vol.12 , pp. 682-687
    • Nicoletti, F.1    Di Marco, R.2    Patti, F.3    Zaccone, P.4    L'Episcopo, M.R.5    Reggio, E.6    Xiang, M.7    Nicoletti, A.8    Reggio, A.9
  • 38
    • 20144389230 scopus 로고    scopus 로고
    • Interferon-β1a therapy for HTLV-I-associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) reduces HTLV-I-specific CD8+ T cells: analysis of HAM/TSP biomarkers
    • Oh U., Yamano Y., Mora C.A., Ohayon J., Bagnato F., Buttman J., Dambrosia J., Leist T., McFarland H.F., and Jacobson S. Interferon-β1a therapy for HTLV-I-associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) reduces HTLV-I-specific CD8+ T cells: analysis of HAM/TSP biomarkers. Ann. Neurol. 57 (2005) 526-534
    • (2005) Ann. Neurol. , vol.57 , pp. 526-534
    • Oh, U.1    Yamano, Y.2    Mora, C.A.3    Ohayon, J.4    Bagnato, F.5    Buttman, J.6    Dambrosia, J.7    Leist, T.8    McFarland, H.F.9    Jacobson, S.10
  • 40
    • 0035282476 scopus 로고    scopus 로고
    • Retroviral diseases of the nervous system: pathogenic host response or viral gene-mediated neurovirulence?
    • Power C. Retroviral diseases of the nervous system: pathogenic host response or viral gene-mediated neurovirulence?. Trends Neurosci. 24 (2001) 162-169
    • (2001) Trends Neurosci. , vol.24 , pp. 162-169
    • Power, C.1
  • 41
    • 0030200026 scopus 로고    scopus 로고
    • Recombinant interferon-beta blocks proliferation but enhances interleukin-10 secretion by activated human T-cells
    • Rep M.H., Hintzen R.Q., Polman C.H., and van Lier R.A. Recombinant interferon-beta blocks proliferation but enhances interleukin-10 secretion by activated human T-cells. J. Neuroimmunol. 67 (1996) 111-118
    • (1996) J. Neuroimmunol. , vol.67 , pp. 111-118
    • Rep, M.H.1    Hintzen, R.Q.2    Polman, C.H.3    van Lier, R.A.4
  • 43
    • 0037330509 scopus 로고    scopus 로고
    • Effects of combination therapy of IFNbeta-1a and prednisone on serum immunologic markers in patients with multiple sclerosis
    • Salama H.H., Kolar O.J., Zang Y.C., and Zhang J. Effects of combination therapy of IFNbeta-1a and prednisone on serum immunologic markers in patients with multiple sclerosis. Mult. Scler. 9 (2003) 28-31
    • (2003) Mult. Scler. , vol.9 , pp. 28-31
    • Salama, H.H.1    Kolar, O.J.2    Zang, Y.C.3    Zhang, J.4
  • 46
    • 55849122679 scopus 로고    scopus 로고
    • Nuanced roles of cytokines in three major human brain disorders
    • Steinman L. Nuanced roles of cytokines in three major human brain disorders. Clin. Invest. 118 (2008) 3557-3563
    • (2008) Clin. Invest. , vol.118 , pp. 3557-3563
    • Steinman, L.1
  • 48
    • 34548321364 scopus 로고    scopus 로고
    • Complement activating soluble pattern recognition molecules with collagen-like regions, mannan-binding lectin, ficolins and associated proteins
    • Thiel S. Complement activating soluble pattern recognition molecules with collagen-like regions, mannan-binding lectin, ficolins and associated proteins. Mol. Immunol. 44 (2007) 3875-3888
    • (2007) Mol. Immunol. , vol.44 , pp. 3875-3888
    • Thiel, S.1
  • 50
    • 33846788024 scopus 로고    scopus 로고
    • An assay for mannan-binding lectin (MBL) associated serine protease 3, MASP-3
    • Thiel S., Holmvad S.H., Dahl M., and Jensenius J.C. An assay for mannan-binding lectin (MBL) associated serine protease 3, MASP-3. Mol. Immunol. 43 (2006) 122-191
    • (2006) Mol. Immunol. , vol.43 , pp. 122-191
    • Thiel, S.1    Holmvad, S.H.2    Dahl, M.3    Jensenius, J.C.4
  • 52
    • 0442291926 scopus 로고    scopus 로고
    • The effects of interferon-alpha2a on concentrations of immunoglobulins, complement and lymphocytes in patients with multiple sclerosis
    • Ulvestad E., Aarseth J.H., Vedeler C., Nyland H., and Myhr K.M. The effects of interferon-alpha2a on concentrations of immunoglobulins, complement and lymphocytes in patients with multiple sclerosis. Scand. J. Immunol. 59 (2004) 103-108
    • (2004) Scand. J. Immunol. , vol.59 , pp. 103-108
    • Ulvestad, E.1    Aarseth, J.H.2    Vedeler, C.3    Nyland, H.4    Myhr, K.M.5
  • 53
    • 33748470359 scopus 로고    scopus 로고
    • Fifty years of interferon research: aiming at a moving target
    • Vilcek J. Fifty years of interferon research: aiming at a moving target. Immunity 25 (2006) 343-348
    • (2006) Immunity , vol.25 , pp. 343-348
    • Vilcek, J.1
  • 54
    • 0034855936 scopus 로고    scopus 로고
    • Complex immunomodulatory effects of interferon-beta in multiple sclerosis include the upregulation of T helper 1-associated marker genes
    • Wandinger K.P., Sturzebecher C.S., Bielekova B., Detore G., Rosenwald A., Staudt L.M., McFarland H.F., and Martin R. Complex immunomodulatory effects of interferon-beta in multiple sclerosis include the upregulation of T helper 1-associated marker genes. Ann. Neurol. 50 (2001) 349-357
    • (2001) Ann. Neurol. , vol.50 , pp. 349-357
    • Wandinger, K.P.1    Sturzebecher, C.S.2    Bielekova, B.3    Detore, G.4    Rosenwald, A.5    Staudt, L.M.6    McFarland, H.F.7    Martin, R.8
  • 55
    • 0024504359 scopus 로고
    • The natural history of multiple sclerosis: a geographically based study. 1. Clinical course and disability
    • Weinshenker B.G., Bass B., Rice G.P., Noseworthy J., Carriere W., Baskerville J., and Ebers G.C. The natural history of multiple sclerosis: a geographically based study. 1. Clinical course and disability. Brain 112 (1989) 133-146
    • (1989) Brain , vol.112 , pp. 133-146
    • Weinshenker, B.G.1    Bass, B.2    Rice, G.P.3    Noseworthy, J.4    Carriere, W.5    Baskerville, J.6    Ebers, G.C.7
  • 57
    • 49149116386 scopus 로고    scopus 로고
    • Early identification of interferon-beta responders by ex vivo testing in patients with multiple sclerosis
    • Wiesemann E., Deb M., Hemmer B., Radeke H.H., and Windhagen A. Early identification of interferon-beta responders by ex vivo testing in patients with multiple sclerosis. Clin. Immunol. 128 (2008) 306-313
    • (2008) Clin. Immunol. , vol.128 , pp. 306-313
    • Wiesemann, E.1    Deb, M.2    Hemmer, B.3    Radeke, H.H.4    Windhagen, A.5
  • 58
    • 2342573461 scopus 로고    scopus 로고
    • HIV-1-mediated apoptosis of neuronal cells: proximal molecular mechanisms of HIV-1-induced encephalopathy
    • Xu V., Kulkovsky J., Acheampong E., Nunnari G., Sullivan J., and Pomerantz R.J. HIV-1-mediated apoptosis of neuronal cells: proximal molecular mechanisms of HIV-1-induced encephalopathy. Proc. Natl. Acad. Sci. USA 101 (2004) 7070-7075
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 7070-7075
    • Xu, V.1    Kulkovsky, J.2    Acheampong, E.3    Nunnari, G.4    Sullivan, J.5    Pomerantz, R.J.6
  • 59
    • 34548557423 scopus 로고    scopus 로고
    • Biological variation in circulating levels of mannan-binding lectin (MBL) and MBL-associated serine protease-2 and the influence of age, gender and physical exercise
    • Ytting H., Christensen I.J., Thiel S., Jensenius J.C., Svendsen M.N., Nielsen L., Lottenburger T., and Nielsen H.J. Biological variation in circulating levels of mannan-binding lectin (MBL) and MBL-associated serine protease-2 and the influence of age, gender and physical exercise. Scand. J. Immunol. 66 (2007) 458-464
    • (2007) Scand. J. Immunol. , vol.66 , pp. 458-464
    • Ytting, H.1    Christensen, I.J.2    Thiel, S.3    Jensenius, J.C.4    Svendsen, M.N.5    Nielsen, L.6    Lottenburger, T.7    Nielsen, H.J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.