메뉴 건너뛰기




Volumn 48, Issue 9, 2009, Pages 1036-1044

The transport of high amounts of vascular endothelial growth factor by blood platelets underlines their potential contribution in systemic sclerosis angiogenesis

Author keywords

Blood platelets; Systemic sclerosis; Vascular endothelial growth factor

Indexed keywords

AMIODARONE; ANGIOPOIETIN; ANGIOPOIETIN 1; ANGIOPOIETIN 2; ANTIARRHYTHMIC AGENT; BETA THROMBOGLOBULIN; CALCIUM CHANNEL BLOCKING AGENT; CORTICOSTEROID; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GLUCOCORTICOID; ILOPROST; IMMUNOSUPPRESSIVE AGENT; PADGEM PROTEIN; PLATELET DERIVED GROWTH FACTOR BB; PROTON PUMP INHIBITOR; THROMBIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN; ANGPT1 PROTEIN, HUMAN; ANTITHROMBOCYTIC AGENT; PLATELET DERIVED GROWTH FACTOR; PLATELET-DERIVED GROWTH FACTOR BB; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

EID: 70349784606     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/kep154     Document Type: Article
Times cited : (39)

References (45)
  • 1
    • 33847348491 scopus 로고    scopus 로고
    • Systemic sclerosis: a prototypic multisystem fibrotic disorder
    • Varga J, Abraham D. Systemic sclerosis: a prototypic multisystem fibrotic disorder. J Clin Invest 2007;117:557-67.
    • (2007) J Clin Invest , vol.117 , pp. 557-567
    • Varga, J.1    Abraham, D.2
  • 3
    • 1642475081 scopus 로고    scopus 로고
    • Autologous platelets as a source of proteins for healing and tissue regeneration
    • Anitua E, Andia I, Ardanza B, Nurden P, Nurden AT. Autologous platelets as a source of proteins for healing and tissue regeneration. Thromb Haemost 2004;91:4-15.
    • (2004) Thromb Haemost , vol.91 , pp. 4-15
    • Anitua, E.1    Andia, I.2    Ardanza, B.3    Nurden, P.4    Nurden, A.T.5
  • 4
    • 0020046233 scopus 로고
    • Elevated levels of circulating platelet aggregates and beta-thromboglobulin in scleroderma
    • Kahaleh MB, Osborn I, LeRoy EC. Elevated levels of circulating platelet aggregates and beta-thromboglobulin in scleroderma. Ann Intern Med 1982;96:610-3.
    • (1982) Ann Intern Med , vol.96 , pp. 610-613
    • Kahaleh, M.B.1    Osborn, I.2    LeRoy, E.C.3
  • 5
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med 2003;9:669-76.
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 6
    • 15144340197 scopus 로고    scopus 로고
    • Vascular endothelial growth factor in patients with rheumatoid arthritis
    • Harada M, Mitsuyama K, Yoshida H et al. Vascular endothelial growth factor in patients with rheumatoid arthritis. Scand J Rheumatol 1998;27:377-80.
    • (1998) Scand J Rheumatol , vol.27 , pp. 377-380
    • Harada, M.1    Mitsuyama, K.2    Yoshida, H.3
  • 7
    • 0032435446 scopus 로고    scopus 로고
    • Serum concentrations of vascular endothelial growth factor in collagen diseases
    • Kikuchi K, Kubo M, Kadono T, Yazawa N, Ihn H, Tamaki K. Serum concentrations of vascular endothelial growth factor in collagen diseases. Br J Dermatol 1998;139:1049-51.
    • (1998) Br J Dermatol , vol.139 , pp. 1049-1051
    • Kikuchi, K.1    Kubo, M.2    Kadono, T.3    Yazawa, N.4    Ihn, H.5    Tamaki, K.6
  • 8
    • 34247564964 scopus 로고    scopus 로고
    • Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers
    • Distler O, Del Rosso A, Giacomelli R et al. Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers. Arthritis Res 2002;4:R11.
    • (2002) Arthritis Res , vol.4
    • Distler, O.1    Del Rosso, A.2    Giacomelli, R.3
  • 9
    • 0029793371 scopus 로고    scopus 로고
    • During angiogenesis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium
    • Melder RJ, Koenig GC, Witwer BP, Safabakhsh N, Munn LL, Jain RK. During angiogenesis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium. Nat Med 1996;2:992-7.
    • (1996) Nat Med , vol.2 , pp. 992-997
    • Melder, R.J.1    Koenig, G.C.2    Witwer, B.P.3    Safabakhsh, N.4    Munn, L.L.5    Jain, R.K.6
  • 10
    • 0034672373 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-stimulated endothelial cells promote adhesion and activation of platelets
    • Verheul HM, Jorna AS, Hoekman K, Broxterman HJ, Gebbink MF, Pinedo HM. Vascular endothelial growth factor-stimulated endothelial cells promote adhesion and activation of platelets. Blood 2000;96:4216-21.
    • (2000) Blood , vol.96 , pp. 4216-4221
    • Verheul, H.M.1    Jorna, A.S.2    Hoekman, K.3    Broxterman, H.J.4    Gebbink, M.F.5    Pinedo, H.M.6
  • 11
    • 34249825478 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and its relationship to inflammatory mediators
    • Angelo LS, Kurzrock R. Vascular endothelial growth factor and its relationship to inflammatory mediators. Clin Cancer Res 2007;13:2825-30.
    • (2007) Clin Cancer Res , vol.13 , pp. 2825-2830
    • Angelo, L.S.1    Kurzrock, R.2
  • 12
    • 0018887574 scopus 로고
    • Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee
    • Preliminary criteria for the classification of systemic sclerosis (scleroderma)
    • Preliminary criteria for the classification of systemic sclerosis (scleroderma). Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee. Arthritis Rheum 1980;23:581-90.
    • (1980) Arthritis Rheum , vol.23 , pp. 581-590
  • 13
    • 0023854176 scopus 로고
    • Scleroderma (systemic sclerosis): classification, subsets and pathogenesis
    • LeRoy EC, Black C, Fleischmajer R et al. Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol 1988;15:202-5.
    • (1988) J Rheumatol , vol.15 , pp. 202-205
    • LeRoy, E.C.1    Black, C.2    Fleischmajer, R.3
  • 14
    • 0025152770 scopus 로고
    • Outcome of renal crisis in systemic sclerosis: relation to availability of angiotensin converting enzyme (ACE) inhibitors
    • Steen VD, Costantino JP, Shapiro AP, Medsger TA Jr. Outcome of renal crisis in systemic sclerosis: relation to availability of angiotensin converting enzyme (ACE) inhibitors. Ann Intern Med 1990;113:352-7.
    • (1990) Ann Intern Med , vol.113 , pp. 352-357
    • Steen, V.D.1    Costantino, J.P.2    Shapiro, A.P.3    Medsger T.A., Jr.4
  • 15
    • 0026714852 scopus 로고
    • Raynaud's phenomenon: a proposal for classification
    • LeRoy EC, Medsger TA Jr. Raynaud's phenomenon: a proposal for classification. Clin Exp Rheumatol 1992;10:485-8.
    • (1992) Clin Exp Rheumatol , vol.10 , pp. 485-488
    • LeRoy, E.C.1    Medsger T.A. Jr2
  • 16
    • 0036306621 scopus 로고    scopus 로고
    • Evidence that the platelet integrin alphaIIb beta3 is regulated by the integrin-linked kinase, ILK, in a PI3-kinase dependent pathway
    • Pasquet JM, Noury M, Nurden AT. Evidence that the platelet integrin alphaIIb beta3 is regulated by the integrin-linked kinase, ILK, in a PI3-kinase dependent pathway. Thromb Haemost 2002;88:115-22.
    • (2002) Thromb Haemost , vol.88 , pp. 115-122
    • Pasquet, J.M.1    Noury, M.2    Nurden, A.T.3
  • 17
    • 0035291003 scopus 로고    scopus 로고
    • A short peptide domain of platelet factor 4 blocks angiogenic key events induced by FGF-2
    • Hagedorn M, Zilberberg L, Lozano RM et al. A short peptide domain of platelet factor 4 blocks angiogenic key events induced by FGF-2. FASEB J 2001;15:550-2.
    • (2001) FASEB J , vol.15 , pp. 550-552
    • Hagedorn, M.1    Zilberberg, L.2    Lozano, R.M.3
  • 18
    • 0027053487 scopus 로고
    • Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro
    • Pepper MS, Ferrara N, Orci L, Montesano R. Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro. Biochem Biophys Res Commun 1992;189:824-31.
    • (1992) Biochem Biophys Res Commun , vol.189 , pp. 824-831
    • Pepper, M.S.1    Ferrara, N.2    Orci, L.3    Montesano, R.4
  • 19
    • 0027133163 scopus 로고
    • Synergistic effects of vascular endothelial growth factor and basic fibroblast growth factor on the proliferation and cord formation of bovine capillary endothelial cells within collagen gels
    • Goto F, Goto K, Weindel K, Folkman J. Synergistic effects of vascular endothelial growth factor and basic fibroblast growth factor on the proliferation and cord formation of bovine capillary endothelial cells within collagen gels. Lab Invest 1993;69:508-17.
    • (1993) Lab Invest , vol.69 , pp. 508-517
    • Goto, F.1    Goto, K.2    Weindel, K.3    Folkman, J.4
  • 20
    • 33750529948 scopus 로고    scopus 로고
    • VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin
    • Gavard J, Gutkind JS. VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin. Nat Cell Biol 2006;8:1223-34.
    • (2006) Nat Cell Biol , vol.8 , pp. 1223-1234
    • Gavard, J.1    Gutkind, J.S.2
  • 21
    • 0031966498 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) is released from platelets during blood clotting: implications for measurement of circulating VEGF levels in clinical disease
    • Webb NJ, Bottomley MJ, Watson CJ, Brenchley PE. Vascular endothelial growth factor (VEGF) is released from platelets during blood clotting: implications for measurement of circulating VEGF levels in clinical disease. Clin Sci 1998;94: 395-404.
    • (1998) Clin Sci , vol.94 , pp. 395-404
    • Webb, N.J.1    Bottomley, M.J.2    Watson, C.J.3    Brenchley, P.E.4
  • 22
    • 0038376002 scopus 로고    scopus 로고
    • Molecular regulation of vessel maturation
    • Jain RK. Molecular regulation of vessel maturation. Nat Med 2003;9:685-93.
    • (2003) Nat Med , vol.9 , pp. 685-693
    • Jain, R.K.1
  • 23
    • 28444477739 scopus 로고    scopus 로고
    • Scleroderma: from cell and molecular mechanisms to disease models
    • Abraham DJ, Varga J. Scleroderma: from cell and molecular mechanisms to disease models. Trends Immunol 2005;26:587-95.
    • (2005) Trends Immunol , vol.26 , pp. 587-595
    • Abraham, D.J.1    Varga, J.2
  • 24
    • 3142670517 scopus 로고    scopus 로고
    • Uncontrolled expression of vascular endothelial growth factor and its receptors leads to insufficient skin angiogenesis in patients with systemic sclerosis
    • Distler O, Distler JH, Scheid A et al. Uncontrolled expression of vascular endothelial growth factor and its receptors leads to insufficient skin angiogenesis in patients with systemic sclerosis. Circ Res 2004;95:109-16.
    • (2004) Circ Res , vol.95 , pp. 109-116
    • Distler, O.1    Distler, J.H.2    Scheid, A.3
  • 25
    • 30744438818 scopus 로고    scopus 로고
    • The differential expression of VEGF, VEGFR-2, and GLUT-1 proteins in disease subtypes of systemic sclerosis
    • Davies CA, Jeziorska M, Freemont AJ, Herrick AL. The differential expression of VEGF, VEGFR-2, and GLUT-1 proteins in disease subtypes of systemic sclerosis. Hum Pathol 2006;37:190-7.
    • (2006) Hum Pathol , vol.37 , pp. 190-197
    • Davies, C.A.1    Jeziorska, M.2    Freemont, A.J.3    Herrick, A.L.4
  • 26
    • 0037699955 scopus 로고    scopus 로고
    • Angiogenesis in health and disease
    • Carmeliet P. Angiogenesis in health and disease. Nat Med 2003;9:653-60.
    • (2003) Nat Med , vol.9 , pp. 653-660
    • Carmeliet, P.1
  • 27
    • 0020314830 scopus 로고
    • Platelet activation, fibrinolytic activity and circulating immune complexes in Raynaud's phenomenon
    • Kallenberg CG, Vellenga E, Wouda AA, The TH. Platelet activation, fibrinolytic activity and circulating immune complexes in Raynaud's phenomenon. J Rheumatol 1982;9:878-84.
    • (1982) J Rheumatol , vol.9 , pp. 878-884
    • Kallenberg, C.G.1    Vellenga, E.2    Wouda, A.A.3    The, T.H.4
  • 29
    • 0031029290 scopus 로고    scopus 로고
    • Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets
    • Mohle R, Green D, Moore MA, Nachman RL, Rafii S. Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets. Proc Natl Acad Sci USA 1997;94:663-8.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 663-668
    • Mohle, R.1    Green, D.2    Moore, M.A.3    Nachman, R.L.4    Rafii, S.5
  • 30
    • 0031889548 scopus 로고    scopus 로고
    • Release of the angiogenic cytokine vascular endothelial growth factor (VEGF) from platelets: significance for VEGF measurements and cancer biology
    • Banks RE, Forbes MA, Kinsey SE et al. Release of the angiogenic cytokine vascular endothelial growth factor (VEGF) from platelets: significance for VEGF measurements and cancer biology. Br J Cancer 1998;77:956-64.
    • (1998) Br J Cancer , vol.77 , pp. 956-964
    • Banks, R.E.1    Forbes, M.A.2    Kinsey, S.E.3
  • 31
    • 28044461712 scopus 로고    scopus 로고
    • Effect of specimen anticoagulation on the measurement of circulating platelet-derived growth factors
    • Zimmermann R, Koenig J, Zingsem J et al. Effect of specimen anticoagulation on the measurement of circulating platelet-derived growth factors. Clin Chem 2005;51:2365-8.
    • (2005) Clin Chem , vol.51 , pp. 2365-2368
    • Zimmermann, R.1    Koenig, J.2    Zingsem, J.3
  • 32
    • 0025186078 scopus 로고
    • Platelet alpha-granule fibrinogen, albumin, and immunoglobulin G are not synthesized by rat and mouse megakaryocytes
    • Handagama P, Rappolee DA, Werb Z, Levin J, Bainton DF. Platelet alpha-granule fibrinogen, albumin, and immunoglobulin G are not synthesized by rat and mouse megakaryocytes. J Clin Invest 1990;86:1364-8.
    • (1990) J Clin Invest , vol.86 , pp. 1364-1368
    • Handagama, P.1    Rappolee, D.A.2    Werb, Z.3    Levin, J.4    Bainton, D.F.5
  • 34
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996;86:353-64.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 37
    • 40349108592 scopus 로고    scopus 로고
    • The pathology of scleroderma vascular disease
    • vi
    • Fleming JN, Schwartz SM. The pathology of scleroderma vascular disease. Rheum Dis Clin North Am 2008;34:41-55; vi.
    • (2008) Rheum Dis Clin North Am , vol.34 , pp. 41-55
    • Fleming, J.N.1    Schwartz, S.M.2
  • 38
    • 0032215354 scopus 로고    scopus 로고
    • VEGF gene delivery to muscle: potential role for vasculogenesis in adults
    • Springer ML, Chen AS, Kraft PE, Bednarski M, Blau HM. VEGF gene delivery to muscle: potential role for vasculogenesis in adults. Mol Cell 1998;2:549-58.
    • (1998) Mol Cell , vol.2 , pp. 549-558
    • Springer, M.L.1    Chen, A.S.2    Kraft, P.E.3    Bednarski, M.4    Blau, H.M.5
  • 40
    • 0037090776 scopus 로고    scopus 로고
    • Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy
    • Dor Y, Djonov V, Abramovitch R et al. Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy. EMBO J 2002;21:1939-47.
    • (2002) EMBO J , vol.21 , pp. 1939-1947
    • Dor, Y.1    Djonov, V.2    Abramovitch, R.3
  • 41
    • 0022618934 scopus 로고
    • Pharmacokinetics and pharmacodynamics of the prostacyclin analogue iloprost in man
    • Krause W, Krais T. Pharmacokinetics and pharmacodynamics of the prostacyclin analogue iloprost in man. Eur J Clin Pharmacol 1986;30:61-8.
    • (1986) Eur J Clin Pharmacol , vol.30 , pp. 61-68
    • Krause, W.1    Krais, T.2
  • 42
    • 2142854957 scopus 로고
    • cAMP-mediated phosphorylation of the low-Km cAMP phosphodiesterase markedly stimulates its catalytic activity
    • Grant PG, Mannarino AF, Colman RW. cAMP-mediated phosphorylation of the low-Km cAMP phosphodiesterase markedly stimulates its catalytic activity. Proc Natl Acad Sci USA 1988;85:9071-5.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 9071-9075
    • Grant, P.G.1    Mannarino, A.F.2    Colman, R.W.3
  • 43
    • 0034780234 scopus 로고    scopus 로고
    • Systemic sclerosis-related Raynaud's phenomenon: effects of iloprost infusion therapy on serum cytokine, growth factor and soluble adhesion molecule levels
    • Mittag M, Beckheinrich P, Haustein UF. Systemic sclerosis-related Raynaud's phenomenon: effects of iloprost infusion therapy on serum cytokine, growth factor and soluble adhesion molecule levels. Acta Derm Venereol 2001;81:294-7.
    • (2001) Acta Derm Venereol , vol.81 , pp. 294-297
    • Mittag, M.1    Beckheinrich, P.2    Haustein, U.F.3
  • 44
    • 0036200014 scopus 로고    scopus 로고
    • Aerosolized iloprost induces a mild but sustained inhibition of platelet aggregation
    • Beghetti M, Reber G, de MP et al. Aerosolized iloprost induces a mild but sustained inhibition of platelet aggregation. Eur Respir J 2002;19:518-24.
    • (2002) Eur Respir J , vol.19 , pp. 518-524
    • Beghetti, M.1    Reber, G.2    de, M.P.3
  • 45
    • 0038799774 scopus 로고    scopus 로고
    • Natural history of systemic sclerosis and the assessment of disease activity, severity, functional status, and psychologic well-being
    • vi
    • Medsger TA Jr. Natural history of systemic sclerosis and the assessment of disease activity, severity, functional status, and psychologic well-being. Rheum Dis Clin North Am 2003;29:255-73; vi.
    • (2003) Rheum Dis Clin North Am , vol.29 , pp. 255-273
    • Medsger T.A., Jr.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.