Straightforward, racemization-free synthesis of peptides with fairly to very bulky di- and trisubstituted glycines

Tetrahedron

Volumn 65, Issue 45, 2009, Pages 9165-9179

  Pinto, Filipa C S C ^a   Pereira Lima, Sílvia M M A ^a   Maia, Hernâni L S ^a  

^a UNIVERSITY OF MINHO   (Portugal)

Author keywords

, Dialkylglycines; N, , Trialkylglycines; Peptide synthesis; Ugi Passerini reaction

Indexed keywords

1 (N ACETYLAMINO) CYCLOHEXYLCARBONYLGLYCINE TERT BUTYL ESTER; 1 (N BENZYLOXYCARBONYLPHENYLALANYLAMINO) CYCLOHEXYLCARBONYLGLYCINE TERT BUTYL ESTER; 1 (N BENZYLOXYCARBONYLPHENYLALANYLAMINO) CYCLOHEXYLCARBOXYLIC ACID; 4 METHOXYBENZYL DERIVATIVE; ALKYL GROUP; BENZYL DERIVATIVE; CYANAMIDE; GLYCINE DERIVATIVE; N [(1H BENZOTRIAZOL 1 YL) (DIMETHYLAMINO)METHYLENE] N METHYLMETHANAMINIUM HEXAFLUOROPHOSPHATE N OXIDE; N ACETYL ALPHA,ALPHA DIBENZYLGLYCYLGLYCINE TERT BUTYL ESTER; N ACETYL ALPHA,ALPHA DIETHYLGLYCYLGLYCINE TERT BUTYL ESTER; N ACETYL ALPHA,ALPHA DIISOBUTYLGLYCYLGLYCINE TERT BUTYL ESTER; N ACETYL ALPHA,ALPHA DIPROPYLGLYCYLGLYCINE TERT BUTYL ESTER; N BENZYLOXYCARBONYLPHENYLALANYL ALPHA,ALPHA DIBENZYLGLYCINE; N BENZYLOXYCARBONYLPHENYLALANYL ALPHA,ALPHA DIBENZYLGLYCYLGLYCINE TERT BUTYL ESTER; N BENZYLOXYCARBONYLPHENYLALANYL ALPHA,ALPHA DIETHYLGLYCINE; N BENZYLOXYCARBONYLPHENYLALANYL ALPHA,ALPHA DIETHYLGLYCYLGLYCINE TERT BUTYL ESTER; N BENZYLOXYCARBONYLPHENYLALANYL ALPHA,ALPHA DIISOBUTYLGLYCINE; N BENZYLOXYCARBONYLPHENYLALANYL ALPHA,ALPHA DIISOBUTYLGLYCYLGLYCINE TERT BUTYL ESTER; N BENZYLOXYCARBONYLPHENYLALANYL ALPHA,ALPHA DIMETHYLGLYCINE; N BENZYLOXYCARBONYLPHENYLALANYL ALPHA,ALPHA DIMETHYLGLYCYLGLYCINE TERT BUTYL ESTER; N BENZYLOXYCARBONYLPHENYLALANYL ALPHA,ALPHA DIPROPYLGLYCINE; N BENZYLOXYCARBONYLPHENYLALANYL ALPHA,ALPHA DIPROPYLGLYCYLGLYCINE TERT BUTYL ESTER; N BENZYLOXYCARBONYLPHENYLALANYLGLYCYL ALPHA,ALPHA DIBENZYLGLYCINE; N BENZYLOXYCARBONYLPHENYLALANYLGLYCYL ALPHA,ALPHA DIETHYLGLYCINE; N BENZYLOXYCARBONYLPHENYLALANYLGLYCYL ALPHA,ALPHA DIETHYLGLYCYLPHENYLALANYLGLYCINE TERT BUTYL ESTER; N,N' DICYCLOHEHYLCARBODIIMIDE; PENTAPEPTIDE; PEPTIDE DERIVATIVE; TRIPEPTIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; RACEMIZATION; UGI PASSERINI REACTION;

EID: 70349779334     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2009.09.022     Document Type: Article

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