Down-regulation of Cdx2 in colorectal carcinoma cells by the Raf-MEK-ERK 1/2 pathway

Cellular Signalling

Volumn 21, Issue 12, 2009, Pages 1846-1856

  Krueger, Felix ^a   Madeja, Zofia ^a   Hemberger, Myriam ^a   McMahon, Martin ^b   Cook, Simon J ^a   Gaunt, Stephen J ^a  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cdx2; Colorectal cancer; ERK; PKC; Raf 1; TS cells

Indexed keywords

K RAS PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PROTEASOME; PROTEIN KINASE C; RAF PROTEIN; TRANSCRIPTION FACTOR CDX2;

ARTICLE; COLORECTAL CARCINOMA; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TROPHOBLAST; TUMOR SUPPRESSOR GENE;

CARCINOMA; CELL LINE, TUMOR; CELLS, CULTURED; COLORECTAL NEOPLASMS; DOWN-REGULATION; HOMEODOMAIN PROTEINS; HUMANS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PROMOTER REGIONS, GENETIC; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-RAF; STEM CELLS; TROPHOBLASTS;

EID: 70349779168     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2009.07.020     Document Type: Article

References (44)

1. Suh E., and Traber P.G. Mol. Cell. Biol. 16 (1996) 619-625
2. Strumpf D., Mao C.A., Yamanaka Y., Ralston A., Chawengsaksophak K., Beck F., and Rossant J. Development 132 (2005) 2093-2102
3. Gaunt S.J., Drage D., and Trubshaw R.C. Development 135 (2008) 2511-2520
4. Benahmed F., Gross I., Gaunt S.J., Beck F., Jehan F., Domon-Dell C., Martin E., Kedinger M., Freund J.N., and Duluc I. Gastroenterology 135 (2008) 1238-1247
5. Bonhomme C., Duluc I., Martin E., Chawengsaksophak K., Chenard M.P., Kedinger M., Beck F., Freund J.N., and Domon-Dell C. Gut 52 (2003) 1465-1471
6. Mallo G.V., Rechreche H., Frigerio J.M., Rocha D., Zweibaum A., Lacasa M., Jordan B.R., Dusetti N.J., Dagorn J.C., and Iovanna J.L. Int. J. Cancer 74 (1997) 35-44
7. Ee H.C., Erler T., Bhathal P.S., Young G.P., and James R.J. Am. J. Pathol. 147 (1995) 586-592
8. Hinoi T., Tani M., Lucas P.C., Caca K., Dunn R.L., Macri E., Loda M., Appelman H.D., Cho K.R., and Fearon E.R. Am. J. Pathol. 159 (2001) 2239-2248
9. da Costa L.T., He T.C., Yu J., Sparks A.B., Morin P.J., Polyak K., Laken S., Vogelstein B., and Kinzler K.W. Oncogene 18 (1999) 5010-5014
10. Aoki K., Tamai Y., Horiike S., Oshima M., and Taketo M.M. Nat. Genet. 35 (2003) 323-330
11. Dang L.H., Chen F., Ying C., Chun S.Y., Knock S.A., Appelman H.D., and Dang D.T. Oncogene 25 (2006) 2264-2272
12. Witek M.E., Nielsen K., Walters R., Hyslop T., Palazzo J., Schulz S., and Waldman S.A. Clin. Cancer Res. 11 (2005) 8549-8556
13. Kawai H., Tomii K., Toyooka S., Yano M., Murakami M., Tsukuda K., and Shimizu N. Oncol. Rep. 13 (2005) 547-551
14. Schlesinger Y., Straussman R., Keshet I., Farkash S., Hecht M., Zimmerman J., Eden E., Yakhini Z., Ben-Shushan E., Reubinoff B.E., Bergman Y., Simon I., and Cedar H. Nat. Genet. 39 (2007) 232-236
15. Hinoi T., Loda M., and Fearon E.R. J. Biol. Chem. 278 (2003) 44608-44616
16. Lu X., Freund J.N., Muller M., Ravey J., Nicolas J.P., Gueant J.L., and Namour F. Biochimie 90 (2008) 697-704
17. Lorentz O., Cadoret A., Duluc I., Capeau J., Gespach C., Cherqui G., and Freund J.N. Oncogene 18 (1999) 87-92
18. Baron-Delage S., Capeau J., Barbu V., Chastre E., Levy P., Gespach C., and Cherqui G. J. Biol. Chem. 269 (1994) 18686-18693
19. Delage S., Chastre E., Empereur S., Wicek D., Veissiere D., Capeau J., Gespach C., and Cherqui G. Cancer Res. 53 (1993) 2762-2770
20. Bos J.L. Cancer Res. 49 (1989) 4682-4689
21. Voice J.K., Klemke R.L., Le A., and Jackson J.H. J. Biol. Chem. 274 (1999) 17164-17170
22. Yan J., Roy S., Apolloni A., Lane A., and Hancock J.F. J. Biol. Chem. 273 (1998) 24052-24056
23. Kolch W., Heidecker G., Kochs G., Hummel R., Vahidi H., Mischak H., Finkenzeller G., Marme D., and Rapp U.R. Nature 364 (1993) 249-252
24. Marais R., Light Y., Mason C., Paterson H., Olson M.F., and Marshall C.J. Science 280 (1998) 109-112
25. Boughan P.K., Argent R.H., Body-Malapel M., Park J.H., Ewings K.E., Bowie A.G., Ong S.J., Cook S.J., Sorensen O.E., Manzo B.A., Inohara N., Klein N.J., Nunez G., Atherton J.C., and Bajaj-Elliott M. J. Biol. Chem. 281 (2006) 11637-11648
26. Shirasawa S., Furuse M., Yokoyama N., and Sasazuki T. Science 260 (1993) 85-88
27. Ries S., Biederer C., Woods D., Shifman O., Shirasawa S., Sasazuki T., McMahon M., Oren M., and McCormick F. Cell 103 (2000) 321-330
28. Tanaka S., Kunath T., Hadjantonakis A.K., Nagy A., and Rossant J. Science 282 (1998) 2072-2075
29. Balmanno K., and Cook S.J. Oncogene 18 (1999) 3085-3097
30. Vandesompele J., De Preter K., Pattyn F., Poppe B., Van Roy N., De Paepe A., and Speleman F. Genome Biol. 3 (2002) Research0034.1-0034.11
31. Woods D., Parry D., Cherwinski H., Bosch E., Lees E., and McMahon M. Mol. Cell. Biol. 17 (1997) 5598-5611
32. Jin T., and Li H. J. Biol. Chem. 276 (2001) 14752-14758
33. Kim S., Domon-Dell C., Wang Q., Chung D.H., Di Cristofano A., Pandolfi P.P., Freund J.N., and Evers B.M. Gastroenterology 123 (2002) 1163-1178
34. Pilon N., Oh K., Sylvestre J.R., Bouchard N., Savory J., and Lohnes D. Dev. Biol. 289 (2006) 55-63
35. Boulanger J., Vezina A., Mongrain S., Boudreau F., Perreault N., Auclair B.A., Laine J., Asselin C., and Rivard N. J. Biol. Chem. 280 (2005) 18095-18107
36. Gross I., Lhermitte B., Domon-Dell C., Duluc I., Martin E., Gaiddon C., Kedinger M., and Freund J.N. Oncogene 24 (2005) 7955-7963
37. Houde M., Laprise P., Jean D., Blais M., Asselin C., and Rivard N. J. Biol. Chem. 276 (2001) 21885-21894
38. Rings E.H., Boudreau F., Taylor J.K., Moffett J., Suh E.R., and Traber P.G. Gastroenterology 121 (2001) 1437-1450
39. Funakoshi M., Sasaki T., Nishimoto T., and Kobayashi H. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 745-750
40. Lu C.W., Yabuuchi A., Chen L., Viswanathan S., Kim K., and Daley G.Q. Nat. Genet. 40 (2008) 921-926
41. Ng R.K., Dean W., Dawson C., Lucifero D., Madeja Z., Reik W., and Hemberger M. Nat. Cell Biol. 10 (2008) 1280-1290
42. Tsvetkov P., Asher G., Paz A., Reuven N., Sussman J.L., Silman I., and Shaul Y. Proteins 70 (2008) 1357-1366
43. Khundmiri S.J., Dean W.L., McLeish K.R., and Lederer E.D. J. Biol. Chem. 280 (2005) 8705-8713
44. Toma O., Weber N.C., Wolter J.I., Obal D., Preckel B., and Schlack W. Anesthesiology 101 (2004) 1372-1380