Synthesis of a chiral quaternary carbon center bearing a fluorine atom: Enantio- and diastereoselective guanidine-catalyzed addition of fluorocarbon nucleophiles

Angewandte Chemie - International Edition

Volumn 48, Issue 20, 2009, Pages 3627-3631

  Jiang, Zhiyong ^a   Pan, Yuanhang ^a   Zhao, Yujun ^a   Ma, Ting ^a   Lee, Richmond ^a   Yang, Yuanyong ^a   Huang, Kuo Wei ^a   Wong, Ming Wah ^a   Tan, Choon Hong ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Asymmetric catalysis; Fluorine; Guanidine; Michael addition; Transition states

Indexed keywords

ASYMMETRIC CATALYSIS; BIFUNCTIONAL; DFT CALCULATION; DIASTEREOSELECTIVE; ENANTIO; FLUORINE ATOMS; GUANIDINE; MICHAEL ADDITION; QUATERNARY CARBON; TRANSITION STATE; TRANSITION STATES;

ADDITION REACTIONS; ATOMS; BEARINGS (STRUCTURAL); CATALYSIS; PROBABILITY DENSITY FUNCTION; STEREOSELECTIVITY; SULFUR COMPOUNDS;

FLUORINE;

EID: 70349769686     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200900964     Document Type: Article

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