Contractile effects of ghrelin-related peptides on the chicken gastrointestinal tract in vitro

Peptides

Volumn 28, Issue 3, 2007, Pages 617-624

  Kitazawa, Takio ^a   Kaiya, Hiroyuki ^b   Taneike, Tetsuro ^a  

^a RAKUNO GAKUEN UNIVERSITY   (Japan)

^b NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Chicken gastrointestinal tract; Contraction; Ghrelin; Growth hormone secretagogue receptor; Motilin

Indexed keywords

ATROPINE; CARBACHOL; DEXTRO LYSINE; GHRELIN; HISTIDYL DEXTRO TRYPTOPHYLALANYLTRYPTOPHYL DEXTRO PHENYLALANYLLYSINAMIDE; TETRODOTOXIN;

ANIMAL EXPERIMENT; ARTICLE; AVIAN STOMACH; CHICKEN; COLON; CONTROLLED STUDY; CROP; DRUG EFFICACY; DRUG MECHANISM; ELECTRIC FIELD; ESOPHAGUS; GASTROINTESTINAL TRACT; HUMAN; IN VITRO STUDY; MALE; MUSCLE CONTRACTILITY; NONHUMAN; PRIORITY JOURNAL; RAT; SMALL INTESTINE; SMOOTH MUSCLE;

ANIMALS; CHICKENS; ELECTRIC STIMULATION; GASTROINTESTINAL MOTILITY; GASTROINTESTINAL TRACT; MALE; MOTILIN; MUSCLE CONTRACTION; OLIGOPEPTIDES; PEPTIDE HORMONES;

MAMMALIA; RATTUS;

EID: 33846833890     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2006.10.012     Document Type: Article

References (30)

1. Asakawa A., Inui A., Kaga T., Yuzuriha H., Nagata T., Ueno N., et al. Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin. Gastroenterology 120 (2001) 337-345
2. Bowers C.Y. Unnatural growth hormone-releasing peptide begets natural ghrelin. J Clin Endocrinol Metab 86 (2001) 1464-1469
3. Dass N.B., Munonyara M., Bassil A.K., Hervieu G.J., Osbourne S., Corcoran S., et al. Growth hormone secretagogue receptors in rat and human gastrointestinal tract and the effects of ghrelin. Neuroscience 120 (2003) 443-453
4. De Clercq P., Depoortere I., Macielag M., Vandermeers A., Vandermeers-Piret M.C., and Peeters T.L. Isolation, sequence, and bioactivity of chicken motilin. Peptides 17 (1996) 203-208
5. Depoortere I., Thijs T., Thielemans L., Robberecht P., and Peeters T.L. Interaction of the growth hormone-releasing peptides ghrelin and growth hormone-releasing peptide-6 with the motilin receptor in the rabbit gastric antrum. J Pharmacol Exp Ther 305 (2003) 660-667
6. Depoortere I., De Winter B., Thijs T., De Man J., Pelckmans P., and Peeters T.L. Comparison of the gastroprokinetic effects of ghrelin, GHRP-6 and motilin in rats in vivo and in vitro. Eur J Pharmacol 515 (2005) 160-168
7. 3-GHRP-6, in rat fundic strips is mediated through 5-HT receptors. Eur J Pharmacol 537 (2006) 160-165
8. Edholm T., Levin F., Hellstrom P.M., and Schmidt P.T. Ghrelin stimulates motility in the small intestine of rats through intrinsic cholinergic neurons. Regul Pept 121 (2004) 25-30
9. Fukuda H., Mizuta Y., Isomoto H., Takeshima F., Ohnita K., Ohba K., et al. Ghrelin enhances gastric motility through direct stimulation of intrinsic neural pathways and capsaicin-sensitive afferent neurones in rats. Scand J Gastroenterol 39 (2004) 1209-1214
10. Fujino K., Inui A., Asakawa A., Kihara N., Fujimura M., and Fujimiya M. Ghrelin induces fasted motor activity of the gastrointestinal tract in conscious fed rats. J Physiol 550 (2003) 227-240
11. Geelissen S.M., Beck I.M., Darras V.M., Kuhn E.R., and Van der Geyten S. Distribution and regulation of chicken growth hormone secretagogue receptor isoforms. Gen Comp Endocrinol 134 (2003) 167-174
12. Gnanapavan S., Kola B., Bustin S.A., Morris D.G., McGee P., Fairclough P., et al. The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans. J Clin Endocrinol Metab 87 (2002) 2988-2991
13. Kaiya H., Sakata I., Kojima M., Hosoda H., Sakai T., and Kangawa K. Structural determination and histochemical localization of ghrelin in the red-eared slider turtle, Trachemys scripta elegans. Gen Comp Endocrinol 138 (2004) 50-57
14. Kaiya H., Kojima M., Hosoda H., Moriyama S., Takahashi A., Kawauchi H., et al. Peptide purification, complementary deoxyribonucleic acid (DNA) and genomic DNA cloning, and functional characterization of ghrelin in rainbow trout. Endocrinology 144 (2003) 5215-5226
15. Kaiya H., Van Der Geyten S., Kojima M., Hosoda H., Kitajima Y., Matsumoto M., et al. Chicken ghrelin: purification, cDNA cloning, and biological activity. Endocrinology 143 (2002) 3454-3463
16. Kitazawa T., Taneike T., and Ohga A. Functional characterization of neural and smooth muscle motilin receptors in the chicken proventriculus and ileum. Regul Pept 71 (1997) 87-95
17. Kitazawa T., De Smet B., Verbeke K., Depoortere I., and Peeters T.L. Gastric motor effects of peptide and non-peptide ghrelin agonists in mice in vivo and in vitro. Gut 54 (2005) 1078-1084
18. Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., and Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402 (1999) 656-660
19. Kojima M., and Kangawa K. Ghrelin: structure and function. Physiol Rev 85 (2005) 495-522
20. Neglia S., Arcamone N., Esposito V., Gargiulo G., and de Girolamo P. Presence and distribution of ghrelin-immunopositive cells in the chicken gastrointestinal tract. Acta Histochem 107 (2005) 3-9
21. Papotti M., Ghe C., Cassoni P., Catapano F., Deghenghi R., Ghigo E., et al. Growth hormone secretagogue binding sites in peripheral human tissues. J Clin Endocrinol Metab 85 (2000) 3803-3807
22. Peeters T.L. Ghrelin: a new player in the control of gastrointestinal functions. Gut (2005) 1638-1649
23. Poitras Z. Motilin. In: Walsh J.H., and Dockray G.J. (Eds). Gut peptides: biochemistry and physiology (1993), Raven Press, New York 261-303
24. Rodriguez-Sinovas A., Jimenez M., De Clercq P., Peeters T.L., and Vergara P. Rhythmic oscillating complexes in gastrointestinal tract of chickens: a role for motilin. Am J Physiol 272 (1997) G916-G922
25. Saito E.S., Kaiya H., Takagi T., Yamasaki I., Denbow D.M., Kangawa K., et al. Chicken ghrelin and growth hormone-releasing peptide-2 inhibit food intake of neonatal chicks. Eur J Pharmacol 453 (2002) 75-79
26. Takeshita E., Matsuura B., Dong M., Miller L.J., Matsui H., and Onji M. Molecular characterization and distribution of motilin family receptors in the human gastrointestinal tract. J Gastroenterol 41 (2006) 223-230
27. Tomasetto C., Karam S.M., Ribieras S., Masson R., Lefebvre O., Staub A., et al. Identification and characterization of a novel gastric peptide hormone: the motilin-related peptide. Gastroenterology 119 (2000) 395-405
28. Trudel L., Tomasetto C., Rio M.C., Bouin M., Plourde V., Eberling P., et al. Ghrelin/motilin-related peptide is a potent prokinetic to reverse gastric postoperative ileus in rat. Am J Physiol Gastrointest Liver Physiol 282 (2002) G948-G952
29. Wada R., Sakata I., Kaiya H., Nakamura K., Hayashi Y., Kangawa K., et al. Existence of ghrelin-immunopositive and -expressing cells in the proventriculus of the hatching and adult chicken. Regul Pept 111 (2003) 123-128
30. Xu L., Depoortere I., Tomasetto C., Zandecki M., Tang M., Timmermans J.P., et al. Evidence for the presence of motilin, ghrelin, and the motilin and ghrelin receptor in neurons of the myenteric plexus. Regul Pept 124 (2005) 119-125