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Volumn 389, Issue 4, 2009, Pages 640-644

TNFα induces HIF-1α expression through activation of IKKβ

Author keywords

Breast cancer; Hypoxia inducible factor 1 ; I B kinase ; Tumor necrosis factor ; Vascular endothelial growth factor

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; HYPOXIA INDUCIBLE FACTOR 1; I KAPPA B KINASE BETA; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; I KAPPA B KINASE; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

EID: 70349738078     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.09.042     Document Type: Article
Times cited : (30)

References (25)
  • 1
    • 0033233243 scopus 로고    scopus 로고
    • Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1
    • Semenza G.L. Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. Annu. Rev. Cell Dev. Biol. 15 (1999) 551-578
    • (1999) Annu. Rev. Cell Dev. Biol. , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 2
    • 0038037735 scopus 로고    scopus 로고
    • Regulation of angiogenesis by hypoxia: role of the HIF system
    • Pugh C.W., and Ratcliffe P.J. Regulation of angiogenesis by hypoxia: role of the HIF system. Nat. Med. 9 (2003) 677-684
    • (2003) Nat. Med. , vol.9 , pp. 677-684
    • Pugh, C.W.1    Ratcliffe, P.J.2
  • 3
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza G.L. Targeting HIF-1 for cancer therapy. Nat. Rev. 3 (2003) 721-732
    • (2003) Nat. Rev. , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 4
    • 0037490210 scopus 로고    scopus 로고
    • Hypoxia-inducible factor and its biomedical relevance
    • Huang L.E., and Bunn H.F. Hypoxia-inducible factor and its biomedical relevance. J. Biol. Chem. 278 (2003) 19575-19578
    • (2003) J. Biol. Chem. , vol.278 , pp. 19575-19578
    • Huang, L.E.1    Bunn, H.F.2
  • 5
    • 0033181324 scopus 로고    scopus 로고
    • Interleukin-1beta and tumor necrosis factor-alpha stimulate DNA binding of hypoxia-inducible factor-1
    • Hellwig-Burgel T., Rutkowski K., Metzen E., Fandrey J., and Jelkmann W. Interleukin-1beta and tumor necrosis factor-alpha stimulate DNA binding of hypoxia-inducible factor-1. Blood 94 (1999) 1561-1567
    • (1999) Blood , vol.94 , pp. 1561-1567
    • Hellwig-Burgel, T.1    Rutkowski, K.2    Metzen, E.3    Fandrey, J.4    Jelkmann, W.5
  • 6
    • 0034663561 scopus 로고    scopus 로고
    • Interleukin 1 induces hypoxia-inducible factor 1 in human gingival and synovial fibroblasts
    • Thornton R.D., Lane P., Borghaei R.C., Pease E.A., Caro J., and Mochan E. Interleukin 1 induces hypoxia-inducible factor 1 in human gingival and synovial fibroblasts. Biochem. J. 350 Pt. 1 (2000) 307-312
    • (2000) Biochem. J. , vol.350 , Issue.PART 1 , pp. 307-312
    • Thornton, R.D.1    Lane, P.2    Borghaei, R.C.3    Pease, E.A.4    Caro, J.5    Mochan, E.6
  • 7
    • 0035860246 scopus 로고    scopus 로고
    • MAPK and Akt act cooperatively but independently on hypoxia inducible factor-1alpha in rasV12 upregulation of VEGF
    • Sodhi A., Montaner S., Miyazaki H., and Gutkind J.S. MAPK and Akt act cooperatively but independently on hypoxia inducible factor-1alpha in rasV12 upregulation of VEGF. Biochem. Biophys. Res. Commun. 287 (2001) 292-300
    • (2001) Biochem. Biophys. Res. Commun. , vol.287 , pp. 292-300
    • Sodhi, A.1    Montaner, S.2    Miyazaki, H.3    Gutkind, J.S.4
  • 8
    • 0034654174 scopus 로고    scopus 로고
    • Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics
    • Zhong H., Chiles K., Feldser D., Laughner E., Hanrahan C., Georgescu M.M., Simons J.W., and Semenza G.L. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics. Cancer Res. 60 (2000) 1541-1545
    • (2000) Cancer Res. , vol.60 , pp. 1541-1545
    • Zhong, H.1    Chiles, K.2    Feldser, D.3    Laughner, E.4    Hanrahan, C.5    Georgescu, M.M.6    Simons, J.W.7    Semenza, G.L.8
  • 9
    • 0035037527 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase kinase inhibitor PD98059 blocks the trans-activation but not the stabilization or DNA binding ability of hypoxia-inducible factor-1alpha
    • Hur E., Chang K.Y., Lee E., Lee S.K., and Park H. Mitogen-activated protein kinase kinase inhibitor PD98059 blocks the trans-activation but not the stabilization or DNA binding ability of hypoxia-inducible factor-1alpha. Mol. Pharmacol. 59 (2001) 1216-1224
    • (2001) Mol. Pharmacol. , vol.59 , pp. 1216-1224
    • Hur, E.1    Chang, K.Y.2    Lee, E.3    Lee, S.K.4    Park, H.5
  • 10
    • 0037515549 scopus 로고    scopus 로고
    • MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300
    • Sang N., Stiehl D.P., Bohensky J., Leshchinsky I., Srinivas V., and Caro J. MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300. J. Biol. Chem. 278 (2003) 14013-14019
    • (2003) J. Biol. Chem. , vol.278 , pp. 14013-14019
    • Sang, N.1    Stiehl, D.P.2    Bohensky, J.3    Leshchinsky, I.4    Srinivas, V.5    Caro, J.6
  • 15
    • 0036713778 scopus 로고    scopus 로고
    • TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
    • Inoki K., Li Y., Zhu T., Wu J., and Guan K.L. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat. Cell Biol. 4 (2002) 648-657
    • (2002) Nat. Cell Biol. , vol.4 , pp. 648-657
    • Inoki, K.1    Li, Y.2    Zhu, T.3    Wu, J.4    Guan, K.L.5
  • 16
    • 17444431201 scopus 로고    scopus 로고
    • Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis
    • Ma L., Chen Z., Erdjument-Bromage H., Tempst P., and Pandolfi P.P. Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis. Cell 121 (2005) 179-193
    • (2005) Cell , vol.121 , pp. 179-193
    • Ma, L.1    Chen, Z.2    Erdjument-Bromage, H.3    Tempst, P.4    Pandolfi, P.P.5
  • 17
    • 53249129484 scopus 로고    scopus 로고
    • Advances in targeting IKK and IKK-related kinases for cancer therapy
    • Lee D.F., and Hung M.C. Advances in targeting IKK and IKK-related kinases for cancer therapy. Clin. Cancer Res. 14 (2008) 5656-5662
    • (2008) Clin. Cancer Res. , vol.14 , pp. 5656-5662
    • Lee, D.F.1    Hung, M.C.2
  • 18
    • 70349140915 scopus 로고    scopus 로고
    • Phosphorylation of ARD1 by IKKbeta contributes to its destabilization and degradation
    • Kuo H.P., Lee D.F., Xia W., Lai C.C., Li L.Y., and Hung M.C. Phosphorylation of ARD1 by IKKbeta contributes to its destabilization and degradation. Biochem Biophys. Res. Commun. 389 (2009) 156-161
    • (2009) Biochem Biophys. Res. Commun. , vol.389 , pp. 156-161
    • Kuo, H.P.1    Lee, D.F.2    Xia, W.3    Lai, C.C.4    Li, L.Y.5    Hung, M.C.6
  • 19
    • 38149108890 scopus 로고    scopus 로고
    • All roads lead to mTOR: integrating inflammation and tumor angiogenesis
    • Lee D.F., and Hung M.C. All roads lead to mTOR: integrating inflammation and tumor angiogenesis. Cell Cycle 6 (2007) 3011-3014
    • (2007) Cell Cycle , vol.6 , pp. 3011-3014
    • Lee, D.F.1    Hung, M.C.2
  • 21
    • 17144372970 scopus 로고    scopus 로고
    • A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells
    • Li Y.M., Zhou B.P., Deng J., Pan Y., Hay N., and Hung M.C. A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells. Cancer Res. 65 (2005) 3257-3263
    • (2005) Cancer Res. , vol.65 , pp. 3257-3263
    • Li, Y.M.1    Zhou, B.P.2    Deng, J.3    Pan, Y.4    Hay, N.5    Hung, M.C.6
  • 23
    • 0033404948 scopus 로고    scopus 로고
    • Met expression is associated with poor outcome in patients with axillary lymph node negative breast carcinoma
    • Camp R.L., Rimm E.B., and Rimm D.L. Met expression is associated with poor outcome in patients with axillary lymph node negative breast carcinoma. Cancer 86 (1999) 2259-2265
    • (1999) Cancer , vol.86 , pp. 2259-2265
    • Camp, R.L.1    Rimm, E.B.2    Rimm, D.L.3
  • 24
    • 0029039195 scopus 로고
    • Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia
    • Levy A.P., Levy N.S., Wegner S., and Goldberg M.A. Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia. J. Biol. Chem. 270 (1995) 13333-13340
    • (1995) J. Biol. Chem. , vol.270 , pp. 13333-13340
    • Levy, A.P.1    Levy, N.S.2    Wegner, S.3    Goldberg, M.A.4
  • 25
    • 11244280137 scopus 로고    scopus 로고
    • Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer
    • Lo H.W., Xia W., Wei Y., Ali-Seyed M., Huang S.F., and Hung M.C. Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer. Cancer Res. 65 (2005) 338-348
    • (2005) Cancer Res. , vol.65 , pp. 338-348
    • Lo, H.W.1    Xia, W.2    Wei, Y.3    Ali-Seyed, M.4    Huang, S.F.5    Hung, M.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.