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Volumn 32, Issue 8, 2009, Pages 793-802

IL-4 suppresses very late antigen-4 expression which is required for therapeutic th1 t-cell trafficking into tumors

Author keywords

IL 4; Melanoma; T helper 1; VLA 4; VLA 6

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12P70; INTERLEUKIN 4 RECEPTOR; LAMININ; RECOMBINANT INTERLEUKIN 4; STAT6 PROTEIN; VASCULAR CELL ADHESION MOLECULE 1; VERY LATE ACTIVATION ANTIGEN 4; VERY LATE ACTIVATION ANTIGEN 6;

EID: 70349694504     PISSN: 15249557     EISSN: None     Source Type: Journal    
DOI: 10.1097/CJI.0b013e3181acec1e     Document Type: Article
Times cited : (25)

References (37)
  • 1
    • 0024353079 scopus 로고
    • TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann TR, Co.man RL. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol. 1989;7:145-173.
    • (1989) Annu Rev Immunol , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coman, R.L.2
  • 2
    • 0032033419 scopus 로고    scopus 로고
    • Cytokines induce the development of functionally heterogeneous T helper cell subsets
    • O'Garra A. Cytokines induce the development of functionally heterogeneous T helper cell subsets. Immunity. 1998;8: 275-283.
    • (1998) Immunity , vol.8 , pp. 275-283
    • O'Garra, A.1
  • 3
    • 33847206969 scopus 로고    scopus 로고
    • IL-17 family cytokines and the expanding diversity of effector T cell lineages
    • Weaver CT, Hatton RD, Mangan PR, et al. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu Rev Immunol. 2007;25:821-852.
    • (2007) Annu Rev Immunol , vol.25 , pp. 821-852
    • Weaver, C.T.1    Hatton, R.D.2    Mangan, P.R.3
  • 4
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17- producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • Harrington LE, Hatton RD, Mangan PR, et al. Interleukin 17- producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol. 2005;6: 1123-1132.
    • (2005) Nat Immunol , vol.6 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3
  • 5
    • 0035180065 scopus 로고    scopus 로고
    • Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance
    • Sakaguchi S, Sakaguchi N, Shimizu J, et al. Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev. 2001; 182:18-32.
    • (2001) Immunol Rev , vol.182 , pp. 18-32
    • Sakaguchi, S.1    Sakaguchi, N.2    Shimizu, J.3
  • 6
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
    • Chen Y, Kuchroo VK, Inobe J, et al. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science. 1994;265:1237-1240.
    • (1994) Science , vol.265 , pp. 1237-1240
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.3
  • 7
    • 0031127143 scopus 로고    scopus 로고
    • T-cell subsets: Recruiting the right kind of help
    • Lichtman AH, Abbas AK. T-cell subsets: recruiting the right kind of help. Curr Biol. 1997;7:R242-R244.
    • (1997) Curr Biol , vol.7
    • Lichtman, A.H.1    Abbas, A.K.2
  • 8
    • 0032504982 scopus 로고    scopus 로고
    • T-cell subsets: Chemokine receptors guide the way
    • O'Garra A, McEvoy LM, Zlotnik A. T-cell subsets: chemokine receptors guide the way. Curr Biol. 1998;8:R646-R649.
    • (1998) Curr Biol , vol.8
    • O'Garra, A.1    McEvoy, L.M.2    Zlotnik, A.3
  • 9
    • 0033457890 scopus 로고    scopus 로고
    • Th1/Th2 subsets: Distinct di.erences in homing and chemokine receptor expression?
    • Syrbe U, Siveke J, Hamann A. Th1/Th2 subsets: distinct di.erences in homing and chemokine receptor expression? Springer Semin Immunopathol. 1999;21:263-285.
    • (1999) Springer Semin Immunopathol , vol.21 , pp. 263-285
    • Syrbe, U.1    Siveke, J.2    Hamann, A.3
  • 10
    • 0031012138 scopus 로고    scopus 로고
    • P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into in.ammed tissues
    • Austrup F, Vestweber D, Borges E, et al. P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into in.ammed tissues. Nature. 1997;385:81-83.
    • (1997) Nature , vol.385 , pp. 81-83
    • Austrup, F.1    Vestweber, D.2    Borges, E.3
  • 11
    • 0031963014 scopus 로고    scopus 로고
    • Differential expression of chemokine receptors and chemotactic responsiveness responsiveness of type 1 T helper cells (Th1s) and Th2s
    • Bonecchi R, Bianchi G, Bordignon PP, et al. Differential expression of chemokine receptors and chemotactic responsiveness responsiveness of type 1 T helper cells (Th1s) and Th2s. J Exp Med. 1998;187:129-134.
    • (1998) J Exp Med , vol.187 , pp. 129-134
    • Bonecchi, R.1    Bianchi, G.2    Bordignon, P.P.3
  • 12
    • 34447132205 scopus 로고    scopus 로고
    • Preferential expression of very late antigen-4 on type 1 CTL cells plays a critical role in tra.cking into central nervous system tumors
    • Sasaki K, Zhu X, Vasquez C, et al. Preferential expression of very late antigen-4 on type 1 CTL cells plays a critical role in tra.cking into central nervous system tumors. Cancer Res. 2007;67:6451-6458.
    • (2007) Cancer Res , vol.67 , pp. 6451-6458
    • Sasaki, K.1    Zhu, X.2    Vasquez, C.3
  • 13
    • 33646261645 scopus 로고    scopus 로고
    • Adoptive transfer of type 1 CTL mediates effective anti-central nervous system tumor response: Critical roles of IFN-inducible protein-10
    • Nishimura F, Dusak JE, Eguchi J, et al. Adoptive transfer of type 1 CTL mediates effective anti-central nervous system tumor response: critical roles of IFN-inducible protein-10. Cancer Res. 2006;66:4478-4487.
    • (2006) Cancer Res , vol.66 , pp. 4478-4487
    • Nishimura, F.1    Dusak, J.E.2    Eguchi, J.3
  • 14
    • 33745820353 scopus 로고    scopus 로고
    • Suppression of antitumor immunity by IL-10 and TGF-beta-producing T cells in.ltrating the growing tumor: In.uence of tumor environment on the induction of CD4+ and CD8+ regulatory T cells
    • Jarnicki AG, Lysaght J, Todryk S, et al. Suppression of antitumor immunity by IL-10 and TGF-beta-producing T cells in.ltrating the growing tumor: in.uence of tumor environment on the induction of CD4+ and CD8+ regulatory T cells. J Immunol. 2006;177:896-904.
    • (2006) J Immunol , vol.177 , pp. 896-904
    • Jarnicki, A.G.1    Lysaght, J.2    Todryk, S.3
  • 15
    • 0032433126 scopus 로고    scopus 로고
    • Genetic regulation of commitment to interleukin 4 production by a CD4+ T cellintrinsic mechanism
    • Bix M, Wang ZE, Thiel B, et al. Genetic regulation of commitment to interleukin 4 production by a CD4+ T cellintrinsic mechanism. J Exp Med. 1998;188:2289-2299.
    • (1998) J Exp Med , vol.188 , pp. 2289-2299
    • Bix, M.1    Wang, Z.E.2    Thiel, B.3
  • 16
    • 0033010373 scopus 로고    scopus 로고
    • The IL-4 receptor: Signaling mechanisms and biologic functions
    • Nelms K, Keegan AD, Zamorano J, et al. The IL-4 receptor: signaling mechanisms and biologic functions. Annu Rev Immunol. 1999;17:701-738.
    • (1999) Annu Rev Immunol , vol.17 , pp. 701-738
    • Nelms, K.1    Keegan, A.D.2    Zamorano, J.3
  • 17
    • 0029876629 scopus 로고    scopus 로고
    • Stat6 is required for mediating responses to IL-4 and for development of Th2 cells
    • Kaplan MH, Schindler U, Smiley ST, et al. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity. 1996;4:313-319.
    • (1996) Immunity , vol.4 , pp. 313-319
    • Kaplan, M.H.1    Schindler, U.2    Smiley, S.T.3
  • 18
    • 0028173015 scopus 로고
    • The pathophysiologic role of alpha 4 integrins in vivo
    • Lobb RR, Hemler ME. The pathophysiologic role of alpha 4 integrins in vivo. J Clin Invest. 1994;94:1722-1728.
    • (1994) J Clin Invest , vol.94 , pp. 1722-1728
    • Lobb, R.R.1    Hemler, M.E.2
  • 19
    • 0025363922 scopus 로고
    • Regulated expression and binding of three VLA (beta 1) integrin receptors on T cells
    • Shimizu Y, Van Seventer GA, Horgan KJ, et al. Regulated expression and binding of three VLA (beta 1) integrin receptors on T cells. Nature. 1990;345:250-253.
    • (1990) Nature , vol.345 , pp. 250-253
    • Shimizu, Y.1    Van Seventer, G.A.2    Horgan, K.J.3
  • 20
    • 0025195765 scopus 로고
    • Roles of adhesion molecules in T-cell recognition: Fundamental similarities between four integrins on resting human T cells (LFA-1, VLA-4, VLA-5, VLA-6) in expression, binding, and costimulation
    • Shimizu Y, van Seventer GA, Horgan KJ, et al. Roles of adhesion molecules in T-cell recognition: fundamental similarities between four integrins on resting human T cells (LFA-1, VLA-4, VLA-5, VLA-6) in expression, binding, and costimulation. Immunol Rev. 1990;114:109-143.
    • (1990) Immunol Rev , vol.114 , pp. 109-143
    • Shimizu, Y.1    Van Seventer, G.A.2    Horgan, K.J.3
  • 21
    • 0034541167 scopus 로고    scopus 로고
    • Tumor-specific CD4+ T cells have a major ''post-licensing'' role in CTL mediated antitumor immunity
    • Marzo AL, Kinnear BF, Lake RA, et al. Tumor-specific CD4+ T cells have a major ''post-licensing'' role in CTL mediated antitumor immunity. J Immunol. 2000;165:6047-6055.
    • (2000) J Immunol , vol.165 , pp. 6047-6055
    • Marzo, A.L.1    Kinnear, B.F.2    Lake, R.A.3
  • 22
    • 49149130306 scopus 로고    scopus 로고
    • Tumor-specific CD4+ T cells render the tumor environment permissive for in.ltration by low-avidity CD8+ T cells
    • Wong SB, Bos R, Sherman LA. Tumor-specific CD4+ T cells render the tumor environment permissive for in.ltration by low-avidity CD8+ T cells. J Immunol. 2008;180: 3122-3131.
    • (2008) J Immunol , vol.180 , pp. 3122-3131
    • Wong, S.B.1    Bos, R.2    Sherman, L.A.3
  • 23
    • 34249677872 scopus 로고    scopus 로고
    • Adoptive transfer of tumorprimed, in vitro-activated, CD4+ T effector cells (TEs) combined with CD8+ TEs provides intratumoral TE proliferation and synergistic antitumor response
    • Wang LX, Shu S, Disis ML, et al. Adoptive transfer of tumorprimed, in vitro-activated, CD4+ T effector cells (TEs) combined with CD8+ TEs provides intratumoral TE proliferation and synergistic antitumor response. Blood. 2007;109: 4865-4876.
    • (2007) Blood , vol.109 , pp. 4865-4876
    • Wang, L.X.1    Shu, S.2    Disis, M.L.3
  • 24
    • 0034668011 scopus 로고    scopus 로고
    • Divergent roles for CD4+ T cells in the priming and effector/memory phases of adoptive immunotherapy
    • Hu HM, Winter H, Urba WJ, et al. Divergent roles for CD4+ T cells in the priming and effector/memory phases of adoptive immunotherapy. J Immunol. 2000;165:4246-4253.
    • (2000) J Immunol , vol.165 , pp. 4246-4253
    • Hu, H.M.1    Winter, H.2    Urba, W.J.3
  • 25
    • 0032824973 scopus 로고    scopus 로고
    • Signaling defects in T lymphocytes of patients with malignancy
    • Whiteside TL. Signaling defects in T lymphocytes of patients with malignancy. Cancer Immunol Immunother. 1999;48: 346-352.
    • (1999) Cancer Immunol Immunother , vol.48 , pp. 346-352
    • Whiteside, T.L.1
  • 26
    • 0033034333 scopus 로고    scopus 로고
    • Down-regulation of HLA class i antigen-processing molecules in malignant melanoma: Association with disease progression
    • Kageshita T, Hirai S, Ono T, et al. Down-regulation of HLA class I antigen-processing molecules in malignant melanoma: association with disease progression. Am J Pathol. 1999;154: 745-754.
    • (1999) Am J Pathol , vol.154 , pp. 745-754
    • Kageshita, T.1    Hirai, S.2    Ono, T.3
  • 27
    • 0025095664 scopus 로고
    • Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response
    • Fearon ER, Pardoll DM, Itaya T, et al. Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response. Cell. 1990;60: 397-403.
    • (1990) Cell , vol.60 , pp. 397-403
    • Fearon, E.R.1    Pardoll, D.M.2    Itaya, T.3
  • 28
    • 20044363610 scopus 로고    scopus 로고
    • CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells
    • Antony PA, Piccirillo CA, Akpinarli A, et al. CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells. J Immunol. 2005;174:2591-2601.
    • (2005) J Immunol , vol.174 , pp. 2591-2601
    • Antony, P.A.1    Piccirillo, C.A.2    Akpinarli, A.3
  • 29
    • 0033213599 scopus 로고    scopus 로고
    • CTLA-4 blockade reverses CD8+ T cell tolerance to tumor by a CD4+ T cell- and IL-2-dependent mechanism
    • Shrikant P, Khoruts A, Mescher MF. CTLA-4 blockade reverses CD8+ T cell tolerance to tumor by a CD4+ T cell- and IL-2-dependent mechanism. Immunity. 1999;11: 483-493.
    • (1999) Immunity , vol.11 , pp. 483-493
    • Shrikant, P.1    Khoruts, A.2    Mescher, M.F.3
  • 30
    • 0032482474 scopus 로고    scopus 로고
    • T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions
    • Schoenberger SP, Toes RE, van der Voort EI, et al. T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature. 1998;393:480-483.
    • (1998) Nature , vol.393 , pp. 480-483
    • Schoenberger, S.P.1    Toes, R.E.2    Van Der Voort, E.I.3
  • 31
    • 0035893748 scopus 로고    scopus 로고
    • CD40 crosslinking bypasses the absolute requirement for CD4 T cells during immunization with melanoma antigen gene-modi.ed dendritic cells
    • Ribas A, Butter.eld LH, Amarnani SN, et al. CD40 crosslinking bypasses the absolute requirement for CD4 T cells during immunization with melanoma antigen gene-modi.ed dendritic cells. Cancer Res. 2001;61:8787-8793.
    • (2001) Cancer Res , vol.61 , pp. 8787-8793
    • Ribas, A.1    Buttereld, L.H.2    Amarnani, S.N.3
  • 32
    • 0034123555 scopus 로고    scopus 로고
    • Melanoma immunotherapy by targeted IL-2 depends on CD4(+) T-cell help mediated by CD40/CD40L interaction
    • Lode HN, Xiang R, Pertl U, et al. Melanoma immunotherapy by targeted IL-2 depends on CD4(+) T-cell help mediated by CD40/CD40L interaction. J Clin Invest. 2000;105: 1623-1630.
    • (2000) J Clin Invest , vol.105 , pp. 1623-1630
    • Lode, H.N.1    Xiang, R.2    Pertl, U.3
  • 33
    • 0033119468 scopus 로고    scopus 로고
    • A critical role for a peritumoral stromal reaction in the induction of T-cell migration responsible for interleukin-12-induced tumor regression
    • Ogawa M, Umehara K, Yu WG, et al. A critical role for a peritumoral stromal reaction in the induction of T-cell migration responsible for interleukin-12-induced tumor regression. Cancer Res. 1999;59:1531-1538.
    • (1999) Cancer Res , vol.59 , pp. 1531-1538
    • Ogawa, M.1    Umehara, K.2    Yu, W.G.3
  • 34
    • 0030810155 scopus 로고    scopus 로고
    • The transcription factor GATA-3 is necessary and su.cient for Th2 cytokine gene expression in CD4 T cells
    • Zheng W, Flavell RA. The transcription factor GATA-3 is necessary and su.cient for Th2 cytokine gene expression in CD4 T cells. Cell. 1997;89:587-596.
    • (1997) Cell , vol.89 , pp. 587-596
    • Zheng, W.1    Flavell, R.A.2
  • 35
    • 0032538985 scopus 로고    scopus 로고
    • Glimcher LH. c-maf promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms
    • Ho IC, Lo D, Glimcher LH. c-maf promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms. J Exp Med. 1998;188:1859-1866.
    • (1998) J Exp Med , vol.188 , pp. 1859-1866
    • Ho, I.C.1    Lo, D.2
  • 36
    • 34247474890 scopus 로고    scopus 로고
    • Tumour microenvironment: Laminin 332 in squamous-cell carcinoma
    • Marinkovich MP. Tumour microenvironment: laminin 332 in squamous-cell carcinoma. Nat Rev Cancer. 2007;7:370-380.
    • (2007) Nat Rev Cancer , vol.7 , pp. 370-380
    • Marinkovich, M.P.1
  • 37
    • 33644912882 scopus 로고    scopus 로고
    • Laminin-5 (laminin-332): Unique biological activity and role in tumor growth and invasion
    • Miyazaki K. Laminin-5 (laminin-332): unique biological activity and role in tumor growth and invasion. Cancer Sci. 2006;97:91-98.
    • (2006) Cancer Sci , vol.97 , pp. 91-98
    • Miyazaki, K.1


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