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Volumn 15, Issue 19, 2009, Pages 6177-6184

Translocator protein blockade reduces prostate tumor growth

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; LORAZEPAM; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; RECEPTOR PROTEIN; TRANSLOCATOR PROTEIN; TRANSLOCATOR PROTEIN RECEPTOR; UNCLASSIFIED DRUG;

EID: 70349667466     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-09-0844     Document Type: Article
Times cited : (43)

References (33)
  • 1
    • 0022574416 scopus 로고
    • The peripheral-type benzodiazepine receptor. Localization to the mitochondrial outer membrane
    • Anholt RR, Pedersen PL, De Souza EB, Snyder SH. The peripheral-type benzodiazepine receptor. Localization to the mitochondrial outer membrane. J Biol Chem 1986;261:576-583
    • (1986) J Biol Chem , vol.261 , pp. 576-583
    • Anholt, R.R.1    Pedersen, P.L.2    De Souza, E.B.3    Snyder, S.H.4
  • 2
    • 0027447948 scopus 로고
    • Peripheral-type benzodiazepine/diazepam binding inhibitor receptor: Biological role in steroidogenic cell function
    • DOI 10.1210/er.14.2.222
    • Papadopoulos V. Peripheral-type benzodiazepine/ diazepam binding inhibitor receptor: biological role in steroidogenic cell function. Endocr Rev 1993;14:222-240 (Pubitemid 23118419)
    • (1993) Endocrine Reviews , vol.14 , Issue.2 , pp. 222-240
    • Papadopoulos, V.1
  • 3
    • 0033566312 scopus 로고    scopus 로고
    • Peripheral-type benzodiazepine receptors in the regulation of proliferation of MCF-7 human breast carcinoma cell line
    • DOI 10.1016/S0006-2952(99)00093-3, PII S0006295299000933
    • Carmel I, Fares FA, Leschiner S, Scherubl H, Weisinger G, Gavish M. Peripheral-type benzodiazepine receptors in the regulation of proliferation of MCF-7 human breast carcinoma cell line. Biochem Pharmacol 1999;58:273-278 (Pubitemid 29255945)
    • (1999) Biochemical Pharmacology , vol.58 , Issue.2 , pp. 273-278
    • Carmel, I.1    Fares, F.A.2    Leschiner, S.3    Scherubl, H.4    Weisinger, G.5    Gavish, M.6
  • 4
    • 0028291770 scopus 로고
    • Characterization of peripheral benzodiazepine receptors in rat prostatic adenocarcinoma
    • DOI 10.1002/pros.2990240509
    • Batra S, Alenfall J. Characterization of peripheral benzodiazepine receptors in rat prostatic adenocarcinoma. Prostate 1994;24:269-278 (Pubitemid 24166956)
    • (1994) Prostate , vol.24 , Issue.5 , pp. 269-278
    • Batra, S.1    Alenfall, J.2
  • 5
    • 0025051933 scopus 로고
    • Increase in peripheral benzodiazepine binding sites in colonic adenocarcinoma
    • Katz Y, Eitan A, Gavish M. Increase in peripheral benzodiazepine binding sites in colonic adenocarcinoma. Oncology 1990;47:139-142 (Pubitemid 20075553)
    • (1990) Oncology , vol.47 , Issue.2 , pp. 139-142
    • Katz, Y.1    Eitan, A.2    Gavish, M.3
  • 6
    • 0025101497 scopus 로고
    • Increased density of peripheral benzodiazepine-binding sites in ovarian carcinomas as compared with benign ovarian tumours and normal ovaries
    • Katz Y, Ben-BaruchG, Kloog Y, Menczer J, Gavish M. Increased density of peripheral benzodiazepinebinding sites in ovarian carcinomas as compared with benign ovarian tumours and normal ovaries. Clin Sci 1990;78:155-158 (Pubitemid 20084053)
    • (1990) Clinical Science , vol.78 , Issue.2 , pp. 155-158
    • Katz, Y.1    Ben-Baruch, G.2    Kloog, Y.3    Menczer, J.4    Gavish, M.5
  • 7
    • 0034027974 scopus 로고    scopus 로고
    • Peripheral benzodiazepine receptor in human endometrium and endometrial carcinoma
    • Batra S, Iosif CS. Peripheral benzodiazepine receptor in human endometrium and endometrial carcinoma. Anticancer Res 2000;20:463-466 (Pubitemid 30189796)
    • (2000) Anticancer Research , vol.20 , Issue.1 A , pp. 463-466
    • Batra, S.1    Iosif, C.S.2
  • 8
    • 0242299669 scopus 로고    scopus 로고
    • Expression of Peripheral Benzodiazepine Receptor (PBR) in Human Tumors: Relationship to Breast, Colorectal, and Prostate Tumor Progression
    • DOI 10.1081/RRS-120025210
    • Han Z, Slack RS, Li W, Papadopoulos V. Expression of peripheral benzodiazepine receptor (PBR) in human tumors: relationship to breast, colorectal, and prostate tumor progression. J Recept Signal Transduct Res 2003;23:225-238 (Pubitemid 37362242)
    • (2003) Journal of Receptors and Signal Transduction , vol.23 , Issue.2-3 , pp. 225-238
    • Han, Z.1    Slack, R.S.2    Li, W.3    Papadopoulos, V.4
  • 9
    • 33746912767 scopus 로고    scopus 로고
    • The permeability transition pore complex in cancer cell death
    • erratum appears in Oncogene. 2006 Oct 26;25(50):6678
    • Brenner C, Grimm S. The permeability transition pore complex in cancer cell death. [erratum appears in Oncogene. 2006 Oct 26;25(50):6678]. Oncogene 2006;25:4744-4756
    • (2006) Oncogene , vol.25 , pp. 4744-4756
    • Brenner, C.1    Grimm, S.2
  • 10
    • 0032526746 scopus 로고    scopus 로고
    • PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection
    • DOI 10.1006/excr.1998.4084
    • Hirsch T, Decaudin D, Susin SA, et al. PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection. Exp Cell Res 1998;241:426-434 (Pubitemid 28366568)
    • (1998) Experimental Cell Research , vol.241 , Issue.2 , pp. 426-434
    • Hirsch, T.1    Decaudin, D.2    Susin, S.A.3    Marchetti, P.4    Larochette, N.5    Resche-Rigon, M.6    Kroemer, G.7
  • 11
    • 0029001681 scopus 로고
    • Expression of peripheral-type benzodiazepine receptor and diazepam binding inhibitor in human astrocytomas: Relationship to cell proliferation
    • Miettinen H, Kononen J, Haapasalo H, et al. Expression of peripheral-type benzodiazepine receptor and diazepam binding inhibitor in human astrocytomas: relationship to cell proliferation. Cancer Res 1995;55:2691-2695
    • (1995) Cancer Res , vol.55 , pp. 2691-2695
    • Miettinen, H.1    Kononen, J.2    Haapasalo, H.3
  • 13
    • 26244457184 scopus 로고    scopus 로고
    • Cell cycle arrest and apoptosis induction in hepatocellular carcinoma cells by HMG-CoA reductase inhibitors. Synergistic antiproliferative action with ligands of the peripheral benzodiazepine receptor
    • DOI 10.1016/j.jhep.2005.04.010, PII S0168827805003296
    • Sutter AP, Maaser K, Hopfner M, Huether A, Schuppan D, Scherubl H. Cell cycle arrest and apoptosis induction in hepatocellular carcinoma cells by HMG-CoA reductase inhibitors. Synergisticantiproliferative action with ligands of the peripheral benzodiazepine receptor. J Hepatol 2005;43:808-816 (Pubitemid 41414506)
    • (2005) Journal of Hepatology , vol.43 , Issue.5 , pp. 808-816
    • Sutter, A.P.1    Maaser, K.2    Hopfner, M.3    Huether, A.4    Schuppan, D.5    Scherubl, H.6
  • 16
    • 0028795087 scopus 로고
    • A new aspect of the antiproliferative action of peripheral-type benzodiazepine receptor ligands
    • Camins A, Diez-Fernandez C, Pujadas E, Camarasa J, Escubedo E. A new aspect of the antiproliferative action of peripheral-type benzodiazepine receptor ligands. Eur J Pharmacol 1995;272:289-292
    • (1995) Eur J Pharmacol , vol.272 , pp. 289-292
    • Camins, A.1    Diez-Fernandez, C.2    Pujadas, E.3    Camarasa, J.4    Escubedo, E.5
  • 19
    • 0021150496 scopus 로고
    • Structural requirements for the binding of benzodiazepines to their peripheral-type sites
    • Wang JK, Taniguchi T, Spector S. Structural requirements for the binding of benzodiazepines to their peripheral-type sites. Mol Pharmacol 1984; 25:349-351 (Pubitemid 14033953)
    • (1984) Molecular Pharmacology , vol.25 , Issue.3 , pp. 349-351
    • Wang, J.K.T.1    Taniguchi, T.2    Spector, S.3
  • 20
    • 0029804458 scopus 로고    scopus 로고
    • Characterization of peripheral benzodiazepine type sites in a cultured murine BV-2 microglial cell line
    • DOI 10.1002/(SICI)1098-1136(199601)16:1<65::AID-GLIA7>3.0.CO;2-A
    • Park CH, Carboni E, Wood PL, Gee KW. Characterization of peripheral benzodiazepine type sites in a cultured murine BV-2 microglial cell line. Glia 1996;16:65-70. (Pubitemid 26350512)
    • (1996) GLIA , vol.16 , Issue.1 , pp. 65-70
    • Park, C.H.1    Carboni, E.2    Wood, P.L.3    Gee, K.W.4
  • 21
    • 0028937362 scopus 로고
    • Modulation of peripheral benzodiazepine receptor density by testosterone in Dunning G prostatic adenocarcinoma
    • Alenfall J, Batra S. Modulation of peripheral benzodiazepine receptor density by testosterone in Dunning G prostatic adenocarcinoma. Life Sci 1995;56:1897-1902
    • (1995) Life Sci , vol.56 , pp. 1897-1902
    • Alenfall, J.1    Batra, S.2
  • 22
    • 0025148492 scopus 로고
    • Identification and distribution of peripheral benzodiazepine binding sites in male rat genital tract
    • DOI 10.1016/0006-2952(90)90321-B
    • Katz Y, Amiri Z,Weizman A, GavishM. Identification and distribution of peripheral benzodiazepine binding sites in male rat genital tract. Biochem Pharmacol 1990;40:817-820 (Pubitemid 20246590)
    • (1990) Biochemical Pharmacology , vol.40 , Issue.4 , pp. 817-820
    • Katz, Y.1    Amiri, Z.2    Weizman, A.3    Gavish, M.4
  • 23
    • 0035313305 scopus 로고    scopus 로고
    • Widely used prostate carcinoma cell lines share common origins
    • DOI 10.1002/pros.1045
    • van Bokhoven A, Varella-Garcia M, Korch C, Hessels D, Miller GJ. Widely used prostate carcinoma cell lines share common origins. Prostate 2001;47:38-51. (Pubitemid 32246751)
    • (2001) Prostate , vol.47 , Issue.1 , pp. 36-51
    • Van Bokhoven, A.1    Varella-Garcia, M.2    Korch, C.3    Hessels, D.4    Miller, G.J.5
  • 24
    • 0037461325 scopus 로고    scopus 로고
    • In vivo and in vitro peripheral-type benzodiazepine receptor polymerization: Functional significance in drug ligand and cholesterol binding
    • Delavoie F, Li H, Hardwick M, et al. In vivo and in vitro peripheral-type benzodiazepine receptor polymerization: functional significance in drug ligand and cholesterol binding. Biochemistry 2003;42:4506-4519
    • (2003) Biochemistry , vol.42 , pp. 4506-4519
    • Delavoie, F.1    Li, H.2    Hardwick, M.3
  • 25
    • 0034008139 scopus 로고    scopus 로고
    • TspO of Rhodobacter sphaeroides. a structural and functional model for the mammalian peripheral benzodiazepine receptor
    • DOI 10.1074/jbc.275.8.5657
    • Yeliseev AA, Kaplan S. TspO of Rhodobacter sphaeroides. A structural and functional model for the mammalian peripheral benzodiazepine receptor. J Biol Chem 2000;275:5657-5667 (Pubitemid 30115205)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.8 , pp. 5657-5667
    • Yeliseev, A.A.1    Kaplan, S.2
  • 26
    • 0026625528 scopus 로고
    • Regulation of peripheraltype benzodiazepine receptors following repeated benzodiazepine administration
    • Calvo DJ,Medina JH. Regulation of peripheraltype benzodiazepine receptors following repeated benzodiazepine administration. Funct Neurol 1992;7:227-230
    • (1992) Funct Neurol , vol.7 , pp. 227-230
    • Calvo, D.J.1    Medina, J.H.2
  • 27
    • 0023762604 scopus 로고
    • Chronicben zodiazepine administration. I. Tolerance is associated with benzodiazepine receptor downregulation and decreased gammaaminobutyric acid A receptor function
    • Miller LG, Greenblatt DJ, Barnhill JG, Shader RI. Chronicben zodiazepine administration. I. Tolerance is associated with benzodiazepine receptor downregulation and decreased gammaaminobutyric acid A receptor function. J Pharmacol Exp Ther 1988;246:170-176
    • (1988) J Pharmacol Exp Ther , vol.246 , pp. 170-176
    • Miller, L.G.1    Greenblatt, D.J.2    Barnhill, J.G.3    Shader, R.I.4
  • 28
    • 0027051943 scopus 로고
    • 3 (peripheral-type benzodiazepine) binding site densities in different types of human brain tumours
    • DOI 10.1007/BF01541799
    • Cornu P, Benavides J, Scatton B, Hauw JJ, Philippon J. Increase in ω3 (peripheral-type benzodiazepine) binding site densities in different types of human brain tumours. A quantitative autoradiography study. Acta Neurochir 1992; 119:146-152 (Pubitemid 23022785)
    • (1992) Acta Neurochirurgica , vol.119 , Issue.1-4 , pp. 146-152
    • Cornu, P.1    Benavides, J.2    Scatton, B.3    Hauw, J.-J.4    Philippon, J.5
  • 29
    • 0033558247 scopus 로고    scopus 로고
    • Peripheral-type benzodiazepine receptor (PBR) in human breast cancer: Correlation of breast cancer cell aggressive phenotype with PBR expression, nuclear localization, and PBR-mediated cell proliferation and nuclear transport of cholesterol
    • Hardwick M, Fertikh D, Culty M, Li H, Vidic B, Papadopoulos V. Peripheral-type benzodiazepine receptor (PBR) in human breast cancer: correlation of breast cancer cell aggressive phenotype with PBR expression, nuclear localization, and PBR-mediated cell proliferation and nuclear transport of cholesterol. Cancer Res 1999;59:831-842 (Pubitemid 29086736)
    • (1999) Cancer Research , vol.59 , Issue.4 , pp. 831-842
    • Hardwick, M.1    Fertikh, D.2    Culty, M.3    Li, H.4    Vidic, B.5    Papadopoulos, V.6
  • 30
    • 0033536556 scopus 로고    scopus 로고
    • Specific binding of benzodiazepines to human breast cancer cell lines
    • DOI 10.1016/S0024-3205(99)00475-0, PII S0024320599004750
    • Beinlich A, Strohmeier R, Kaufmann M, Kuhl H. Specific binding of benzodiazepines to human breast cancer cell lines. Life Sci 1999;65:2099-2108 (Pubitemid 29524859)
    • (1999) Life Sciences , vol.65 , Issue.20 , pp. 2099-2108
    • Beinlich, A.1    Strohmeier, R.2    Kaufmann, M.3    Kuhl, H.4
  • 31
    • 0028031729 scopus 로고
    • In vitro reconstitution of a functional peripheral-type benzodiazepine receptor from mouse Leydig tumor cells
    • Garnier M, Dimchev AB, Boujrad N, Price JM, Musto NA, Papadopoulos V. In vitro reconstitution of a functional peripheral-type benzodiazepine receptor from mouse Leydig tumor cells. Mol Pharmacol 1994;45:201-211
    • (1994) Mol Pharmacol , vol.45 , pp. 201-211
    • Garnier, M.1    Dimchev, A.B.2    Boujrad, N.3    Price, J.M.4    Musto, N.A.5    Papadopoulos, V.6
  • 32
    • 0020522650 scopus 로고
    • Differentiation between two ligands for peripheral benzodiazepine binding sites, [3H]RO5-4864 and [3H]PK 11195, by thermodynamic studies
    • Le Fur G, Vaucher N, Perrier ML, et al. Differentiation between two ligands for peripheral benzodiazepine binding sites, [3H]RO5-4864 and [3H]PK 11195, by thermodynamic studies. Life Sci 1983;33:449-457
    • (1983) Life Sci , vol.33 , pp. 449-457
    • Le Fur, G.1    Vaucher, N.2    Perrier, M.L.3
  • 33
    • 0021326298 scopus 로고
    • Long-term comparison of alprazolam, lorazepam and placebo in patients with an anxiety disorder
    • Cohn JB, Wilcox CS. Long-term comparison of alprazolam, lorazepam and placebo in patients with an anxiety disorder. Pharmacotherapy 1984;2:93-98 (Pubitemid 14148711)
    • (1984) Pharmacotherapy , vol.4 , Issue.2 , pp. 93-98
    • Cohn, J.B.1    Wilcox, C.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.