Serum leptin levels and irritable bowel syndrome: A new hypothesis

Journal of Clinical Gastroenterology

Volumn 43, Issue 9, 2009, Pages 826-830

  Semnani, Shahryar ^a   Roshandel, Gholamreza ^a   Keshtkar, Abbasali ^a   Najafi, Laily ^b   Amiriani, Taghi ^a   Farajollahi, Mehran ^a   Moradi, Abdolvahab ^a   Joshaghani, Hamidreza ^a  

^a GOLESTAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b GOLESTAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Irritable bowel syndrome; Leptin; Stress

Indexed keywords

LEPTIN;

ADULT; ARTICLE; BODY MASS; CASE CONTROL STUDY; CONTROLLED STUDY; DEMOGRAPHY; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HORMONE BLOOD LEVEL; HUMAN; HYPOTHESIS; IRRITABLE COLON; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; QUESTIONNAIRE; STRESS;

ADULT; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; IRRITABLE BOWEL SYNDROME; LEPTIN; LOGISTIC MODELS; MALE; MIDDLE AGED; ODDS RATIO; RISK ASSESSMENT; RISK FACTORS; STRESS, PSYCHOLOGICAL; YOUNG ADULT;

EID: 70349661449     PISSN: 01920790     EISSN: None     Source Type: Journal    
DOI: 10.1097/MCG.0b013e3181986900     Document Type: Article

References (37)

1. Yamada T, Apples DH, eds. Text Book of Gastroenterology. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2003: 1817-1819.
2. Owyang C. Irritable bowel syndrome. In: Kasper DL, Braunwald E, eds. Harrison's Principles of Internal Medicine. 16th ed. New York: McGrawHill; 2005:1789-1793.
3. Foxx-Orenstein A. IBS - review and what's new. Med Gen Med. 2006;8:20.
4. Feldman M, Fridman LS, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 7th ed. Saunders: Philadelphia; 2002: 1794-17963.
5. Folks DG. The interface of psychiatry and irritable bowel syndrome. Curr Psychiatry Rep. 2004;6:210-215. (Pubitemid 38906847)
6. Porcelli P. Psychological abnormalities in patients with irritable bowel syndrome. Indian J Gastroenterol. 2004;23: 63-69. (Pubitemid 38622982)
7. Lea R, Whorwell PJ. Psychological influences on the irritable bowel syndrome. Minerva Med. 2004;95:443-450. (Pubitemid 39481902)
8. Okamura S, Sekiguchi T. Irritable bowel syndrome - criteria, sub-classification, etiology. Nippon Rinsho. 1992;50: 2686-2690.
9. Simrén M, Månsson A, Langkilde AM, et al. Food-related gastrointestinal symptoms in the irritable bowel syndrome. Digestion. 2001;63:108-115. (Pubitemid 32221204)
10. Barreau F, Ferrier L, Fioramonti J, et al. New insights in the etiology and pathophysiology of irritable bowel syndrome: contribution of neonatal stress models. Pediatr Res. 2007;62: 240-245. (Pubitemid 47301468)
11. Yakoob J, Jafri W, Jafri N, et al. Irritable bowel syndrome in search of an etiology: role of Blastocystis hominis. Am J Trop Med Hyg. 2004;70:383-385. (Pubitemid 38525549)
12. Ruchkina IN, Parfenov AI, Osipov GA. Role of dysbiotic disruption in etiology and pathogenesis of irritable bowel syndrome. Eksp Klin Gastroenterol. 2003;57:183.
13. Levy RL, Jones KR, Whitehead WE, et al. Irritable bowel syndrome in twins: heredity and social learning both contribute to etiology. Gastroenterology. 2001;121:799-804.
14. Murray DR, Flynn J, Ratcliffe L, et al. Effect of acute physical and psychological stress on gut autonomic innervation in irritable bowel syndrome. Gastroenterology. 2004;127: 1695-1703. (Pubitemid 39575848)
15. Considine RV, Sinha MK, Heiman ML, et al. Serum immunoreactive leptin concentrations in normal-weight and obese humans. N Engl J Med. 1996;334:292-295. (Pubitemid 26033933)
16. Mantzoros CS. The role of leptin in human obesity and disease. Ann Intern Med. 1999;130:671-680.
17. Konturek PC, Brzozowski T, Sulekova Z, et al. Enhanced expression of leptin following acute gastric injury in rat. J Physiol Pharmacol. 1999;50:587-595. (Pubitemid 30022137)
18. Cohen S, Kamarck T, Mermelstein R. A global measure of perceived stress. J Health Soc Behav. 1983;24:386-396.
19. Al-Ayadhi LY. Neurohormonal changes in medical students during academic stress. Ann Saudi Med. 2005;25:36-40. (Pubitemid 40403222)
20. Mäestu J, Jürimäe J, Jurimae T. Effect of heavy increase in training stress on the plasma leptin concentration in highly trained male rowers. Horm Res. 2003;59:91-94. (Pubitemid 36206667)
21. Rosenbaum M, Nicolson M, Hirsch J, et al. Effects of gender, body composition, and menopause on plasma concentrations of leptin. J Clin Endocrinol Metab. 1996;81: 3424-3427. (Pubitemid 26296228)
22. Rosenbaum M, Nicolson M, Hirsch J, et al. Effects of weight change on plasma leptin concentrations and energy expenditure. J Clin Endocrinol Metab. 1997;82:3647-3654. (Pubitemid 27509351)
23. Hellstrom L, Wahrenberg H, Hruska K, et al. Mechanisms behind gender differences in circulating leptin levels. J Intern Med. 2000;247:457-462. (Pubitemid 30253164)
24. Ruhl CE, Harris TB, Ding J, et al. Body mass index and serum leptin concentration independently estimate percentage body fat in older adults. Am J Clin Nutr. 2007;85:1121-1126. (Pubitemid 46557930)
25. Zhong N, Wu XP, Xu ZR, et al. Relationship of serum leptin with age, body weight, body mass index, and bone mineral density in healthy mainland Chinese women. Clin Chim Acta. 2005;351:161-168. (Pubitemid 39563571)
26. Wong ShL, DePaoli AM, Lee JH, et al. Leptin hormonal kinetics in the fed state: effects of adiposity, age, and gender on endogenous leptin production and clearance rates. J Clin Endocrinol Metab. 2004;89:2672-2677.
27. Moosa MY, Panz VR, Jeenah FY, et al. African women with depression: the effect of imipramine and fluoxetine on body mass index and leptin secretion. J Clin Psychopharmacol. 2003;23:549-552.
28. Yukawa M, McCormick WC, Rajan S, et al. Leptin levels are appropriate for body mass index in older men who experience involuntary weight loss. J Am Geriatr Soc. 2002;50: 1566-1571. (Pubitemid 35024651)
29. Maffei M, Halaas J, Ravussin E. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med. 1996;1:1155-1161.
30. Afifi M. Gender differences in mental health. Singapore Med J. 2007;48:385-391.
31. Karelis AD, Fontaine J, Rabasa-Lhoret R, et al. Psychosocial profile of the metabolically healthy but obese postmenopausal woman. Diabetes Metab. 2006;32:90-91. (Pubitemid 43872603)
32. Elkelis N, Schlaich M, Aggarwal A, et al. Interaction between leptin and the human sympathetic nervous system. Hypertension. 2003;41:1072-1079. (Pubitemid 36548605)
33. Mulak A, Bonaz B. Irritable bowel syndrome: a model of the brain-gut interactions. Med Sci Monit. 2004;10:55-62. (Pubitemid 38525092)
34. Oates M, Woodside B, Walker CD. Chronic leptin administration in developing rats reduces stress responsiveness partly through changes in maternal behavior. Horm Behav. 2000;37: 366-376. (Pubitemid 30432355)
35. Casanova FF, Dieguez C. Neuroendocrine regulation and action of leptin. Front Neuroendocrinol. 1999;20:317-363.
36. Schwartz MW, Seeley RJ. Seminars in medicine of the Beth Israel Deaconess Medical Center. Neuroendocrine responses to starvation and weight loss. N Engl JMed. 1997;336:1803-1811.
37. Piche T, Huet PM, Gelsi E. Fatigue in irritable bowel syndrome: characterization and putative role of leptin. Eur J Gastroenterol Hepatol. 2007;19:23-43. (Pubitemid 46263281)