The Ste-like kinase SLK promotes p53 transactivation and apoptosis (American Journal of Physiology - Renal Physiology (2009) 297, (F971-F980) DOI: 10.1152/ajprenal.00294.2009);The Ste20-like kinase SLK promotes p53 transactivation and apoptosis

American Journal of Physiology - Renal Physiology

Volumn 297, Issue 4, 2009, Pages

  Cybulsky, Andrey V ^a,b   Takano, Tomoko ^a   Guillemette, Julie ^a   Papillon, Joan ^a   Volpini, Rildo A ^a   Di Battista, John A ^a  

^a MCGILL UNIVERSITY   (Canada)

^b ROYAL VICTORIA HOSPITAL   (Canada)

Author keywords

Ischemia reperfusion injury; Kidney; Mitogen activated protein kinases; Phosphorylation

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; JANUS KINASE; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOTRANSFERASE; PIFITHRIN ALPHA; PROTEIN P53; PROTEIN STE20 LIKE KINASE; SERINE; UNCLASSIFIED DRUG;

ANOXIA; APOPTOSIS; ARTICLE; CELL STRAIN COS1; ENHANCER REGION; GENETIC TRANSFECTION; GERMINAL CENTER; GLOMERULUS EPITHELIUM; KIDNEY EPITHELIUM; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REPERFUSION; TRANSACTIVATION;

EID: 70349635306     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.zh2-5752-corr.2009     Document Type: Erratum

References (44)

1. Agarwal ML, Taylor WR, Chernov MV, Chernova OB, Stark GR. The p53 network. J Biol Chem 273: 1-4, 1998.
2. Anderson CW. Human p53 posttranslational modification. Figure 3. http://www.bnl.gov/biology/cellbio/human-p53.asp, 2009.
3. Aoudjit L, Stanciu M, Li H, Lemay S, Takano T. p38 mitogen-activated protein kinase protects glomerular epithelial cells from complement-mediated cell injury. Am J Physiol Renal Physiol 285: F765-F774, 2003. (Pubitemid 37140260)
4. Bain J, McLauchlan H, Elliott M, Cohen P. The specificities of protein kinase inhibitors: an update. Biochem J 371: 199-204, 2003. (Pubitemid 36458094)
5. Chaar Z, O'Reilly P, Gelman I, Sabourin LA. v-Src-dependent down-regulation of the Ste20-like kinase SLK by casein kinase II. J Biol Chem 281: 28193-28199, 2006. (Pubitemid 44414533)
6. Coers W, Reivinen J, Miettinen A, Huitema S, Vos JT, Salant DJ, Weening JJ. Characterization of a rat glomerular visceral epithelial cell line. Exp Nephrol 4: 184-192, 1996. (Pubitemid 26162140)
7. Cybulsky AV, Takano T, Papillon J, Hao W, Mancini A, Di Battista JA, Cybulsky MI. The 3′-untranslated region of the Ste20-like kinase SLK regulates SLK expression. Am J Physiol Renal Physiol 292: F845-F852, 2007. (Pubitemid 46220554)
8. Cybulsky AV, Takano T, Papillon J, Khadir A, Bijian K, Chien CC, Alpers CE, Rabb H. Renal expression and activity of the germinal center kinase SK2. Am J Physiol Renal Physiol 286: F16-F25, 2004. (Pubitemid 38045038)
9. Dan I, Watanabe NM, Kusumi A. The Ste20 group kinases as regulators of MAP kinase cascades. Trends Cell Biol 11: 220-230, 2001. (Pubitemid 32367879)
10. Davies SP, Reddy H, Caivano M, Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 351: 95-105, 2000. (Pubitemid 30781561)
11. Devarajan P. Update on mechanisms of ischemic acute kidney injury. J Am Soc Nephrol 17: 1503-1520, 2006. (Pubitemid 43841396)
12. Ellinger-Ziegelbauer H, Karasuyama H, Yamada E, Tsujikawa K, Todokoro K, Nishida E. Ste20-like kinase (SLK), a regulatory kinase for polo-like kinase (Plk) during the G2/M transition in somatic cells. Genes Cells 5: 491-498, 2000. (Pubitemid 30445495)
13. Fu J, Bian M, Jiang Q, Zhang C. Roles of Aurora kinases in mitosis and tumorigenesis. Mol Cancer Res 5: 1-10, 2007. (Pubitemid 46246762)
14. Hao W, Takano T, Guillemette J, Papillon J, Ren G, Cybulsky AV. Induction of apoptosis by the Ste20-like kinase SLK, a germinal center kinase that activates apoptosis signal-regulating kinase and p38. J Biol Chem 281: 3075-3084, 2006. (Pubitemid 43845917)
15. Huang C, Ma WY, Maxiner A, Sun Y, Dong Z. p38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389. J Biol Chem 274: 12229-12235, 1999. (Pubitemid 129517980)
16. Kelly KJ, Plotkin Z, Vulgamott SL, Dagher PC. P53 mediates the apoptotic response to GTP depletion after renal ischemia-reperfusion: protective role of a p53 inhibitor. J Am Soc Nephrol 14: 128-138, 2003. (Pubitemid 36026304)
17. Komarov PG, Komarova EA, Kondratov RV, Christov-Tselkov K, Coon JS, Chernov MV, Gudkov AV. A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Science 285: 1733-1737, 1999. (Pubitemid 29428873)
18. Koseki C, Herzlinger D, Al-Awqati Q. Apoptosis in metanephric development. J Cell Biol 119: 1327-1333, 1992.
19. Kyriakis JM. Signaling by the germinal center kinase family of protein kinases. J Biol Chem 274: 5259-5262, 1999. (Pubitemid 29109164)
20. Kyriakis JM, Avruch J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 81: 807-869, 2001. (Pubitemid 32267078)
21. Larochelle S, Merrick KA, Terret ME, Wohlbold L, Barboza NM, Zhang C, Shokat KM, Jallepalli PV, Fisher RP. Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells. Mol Cell 25: 839-850, 2007. (Pubitemid 46442792)
22. Lavin MF, Gueven N. The complexity of p53 stabilization and activation. Cell Death Differ 13: 941-950, 2006.
23. Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 88: 323-331, 1997.
24. Lin Y, Khokhlatchev A, Figeys D, Avruch J. Death-associated protein 4 binds MST1 and augments MST1-induced apoptosis. J Biol Chem 277: 47991-48001, 2002. (Pubitemid 35470744)
25. Marshall CB, Pippin JW, Krofft RD, Shankland SJ. Puromycin aminonucleoside induces oxidant-dependent DNA damage in podocytes in vitro and in vivo. Kidney Int 70: 1962-1973, 2006.
26. Olsson A, Manzl C, Strasser A, Villunger A. How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression? Cell Death Differ 14: 1561-1575, 2007. (Pubitemid 47278842)
27. O'Reilly PG, Wagner S, Franks DJ, Cailliau K, Browaeys E, Dissous C, Sabourin LA. The Ste20-like kinase SLK is required for cell cycle progression through G2. J Biol Chem 280: 42383-42390, 2005. (Pubitemid 43023210)
28. Oren M. Decision making by p53: life, death and cancer. Cell Death Differ 10: 431-442, 2003. (Pubitemid 36626355)
29. Pike AC, Rellos P, Niesen FH, Turnbull A, Oliver AW, Parker SA, Turk BE, Pearl LH, Knapp S. Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites. EMBO J 27: 704-714, 2008. (Pubitemid 351273130)
30. Pombo CM, Bonventre JV, Molnar A, Kyriakis J, Force T. Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway. EMBO J 15: 4537-4546, 1996. (Pubitemid 26294572)
31. Pombo CM, Tsujita T, Kyriakis JM, Bonventre JV, Force T. Activation of the Ste20-like oxidant stress response kinase-1 during the initial stages of chemical anoxia-induced necrotic cell death. Requirement for dual inputs of oxidant stress and increased cytosolic [Ca2+]. J Biol Chem 272: 29372-29379, 1997. (Pubitemid 27498232)
32. Racusen LC, Prozialeck DH, Solez K. Glomerular epithelial cell changes after ischemia or dehydration. Possible role of angiotensin II. Am J Pathol 114: 157-163, 1984. (Pubitemid 14179863)
33. Rippe C, Rippe A, Larsson A, Asgeirsson D, Rippe B. Nature of glomerular capillary permeability changes following acute renal ischemia-reperfusion injury in rats. Am J Physiol Renal Physiol 291: F1362-F1368, 2006. (Pubitemid 44887250)
34. Rocha S, Campbell KJ, Roche KC, Perkins ND. The p53-inhibitor pifithrin-alpha inhibits firefly luciferase activity in vivo and in vitro. BMC Mol Biol 4: 9, 2003. (Pubitemid 38693032)
35. Sabourin LA, Rudnicki MA. Induction of apoptosis by SLK, a Ste20-related kinase. Oncogene 18: 7566-7575, 1999.
36. Sabourin LA, Tamai K, Seale P, Wagner J, Rudnicki MA. Caspase 3 cleavage of the Ste20-related kinase SLK releases and activates an apoptosis-inducing kinase domain and an actin-disassembling region. Mol Cell Biol 20: 684-696, 2000. (Pubitemid 30023110)
37. Sutton TA, Wilkinson J, Mang HE, Knipe NL, Plotkin Z, Hosein M, Zak K, Wittenborn J, Dagher PC. p53 regulates renal expression of HIF-1α and pVHL under physiological conditions and after ischemia-reperfusion injury. Am J Physiol Renal Physiol 295: F1666-F1677, 2008.
38. Takano T, Cybulsky AV, Yang X, Aoudjit L. Complement C5b-9 induces cyclooxygenase-2 gene transcription in glomerular epithelial cells. Am J Physiol Renal Physiol 281: F841-F850, 2001. (Pubitemid 33123830)
39. Vousden KH. Apoptosis. p53 and PUMA: a deadly duo. Science 309: 1685-1686, 2005.
40. Wada T, Pippin JW, Marshall CB, Griffin SV, Shankland SJ. Dexamethasone prevents podocyte apoptosis induced by puromycin aminonucleoside: role of p53 and Bcl-2-related family proteins. J Am Soc Nephrol 16: 2615-2625, 2005.
41. Wagner MC, Rhodes G, Wang E, Pruthi V, Arif E, Saleem MA, Wean SE, Garg P, Verma R, Holzman LB, Gattone V, Molitoris BA, Nihalani D. Ischemic injury to kidney induces glomerular podocyte effacement and dissociation of slit diaphragm proteins Neph1 and ZO-1. J Biol Chem 283: 35579-35589, 2008.
42. Wang Z, Canagarajah BJ, Boehm JC, Kassisa S, Cobb MH, Young PR, Abdel-Meguid S, Adams JL, Goldsmith EJ. Structural basis of inhibitor selectivity in MAP kinases. Structure 6: 1117-1128, 1998. (Pubitemid 28434115)
43. Zacchi P, Gostissa M, Uchida T, Salvagno C, Avolio F, Volinia S, Ronai Z, Blandino G, Schneider C, Del Sal G. The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults. Nature 419: 853-857, 2002. (Pubitemid 35238573)
44. Zheng H, You H, Zhou XZ, Murray SA, Uchida T, Wulf G, Gu L, Tang X, Lu KP, Xiao ZX. The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response. Nature 419: 849-853, 2002. (Pubitemid 35238572)