SAP97 regulates Kir2.3 channels by multiple mechanisms

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 297, Issue 4, 2009, Pages

  Vikstrom, Karen L ^a,c   Vaidyanathan, Ravi ^a,c   Levinsohn, Susan ^a   O'Connell, Ryan P ^a,d   Qian, Yueming ^a   Crye, Mark ^a   Mills, Jeffrey H ^b   Anumonwo, Justus M B ^a,c  

^a SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

^b State University of New York Upstate Medical University: College of Medicine   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Channelosome; Inward rectifier; Membrane cytoskeleton; Postsynaptic density protein domain

Indexed keywords

INWARDLY RECTIFYING POTASSIUM CHANNEL; PROTEIN KIR2.3; PROTEIN SAP 97; SIGNALING LYMPHOCYTE ACTIVATION MOLECULE ASSOCIATED PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE; CELL STRAIN HEK293; CELL SURFACE; CONTROLLED STUDY; HUMAN; HUMAN CELL; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BINDING SITES; CELL LINE; CELL MEMBRANE; CYTOPLASMIC VESICLES; GUINEA PIGS; HEART ATRIA; HUMANS; ION CHANNEL GATING; MEMBRANE POTENTIALS; MEMBRANE PROTEINS; MYOCARDIUM; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RATS; SHEEP; TRANSFECTION;

EID: 70349631788     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00638.2008     Document Type: Article

References (40)

1. Abi-Char J, El Haou S, Balse E, Neyroud N, Vranckx R, Coulombe A, Hatem SN. The anchoring protein SAP97 retains Kv1.5 channels in the plasma membrane of cardiac myocytes. Am J Physiol Heart Circ Physiol 294: H1851-H1861, 2008.
2. Brone B, Eggermont J. PDZ proteins retain and regulate membrane transporters in polarized epithelial cell membranes. Am J Physiol Cell Physiol 288: C20-C29, 2005. (Pubitemid 39658423)
3. Cai M, Jordan PC. How does vestibule surface charge affect ion conduction and toxin binding in a sodium channel? Biophys J 57: 883-891, 1990. (Pubitemid 20111247)
4. Dhamoon AS, Pandit SV, Sarmast F, Parisian KR, Guha P, Li Y, Bagwe S, Taffet SM, Anumonwo Unique Kir2 JMB. x properties determine regional and species differences in the cardiac inward rectifier K+ current. Circ Res 94: 1332-1339, 2004. (Pubitemid 38724479)
5. Dobrev D, Wettwer E, Kortner A, Knaut M, Schuler S, Ravens U. Human inward rectifier potassium channels in chronic and postoperative atrial fibrillation. Cardiovasc Res 54: 397-404, 2002. (Pubitemid 34327918)
6. Doyle DA, Morais Cabral J, Pfuetzner RA, Kuo A, Gulbis JM, Cohen SL, Chait BT, MacKinnon R. The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science 280: 69-77, 1998. (Pubitemid 28169082)
7. Horio Y, Hibino H, Inanobe A, Yamada M, Ishii M, Tada Y, Satoh E, Hata Y, Takai Y, Kurachi Y. Clustering and enhanced activity of an inwardly rectifying potassium channel, Kir4.1, by an anchoring protein, PSD-95/SAP90. J Biol Chem 272: 12885-12888, 1997. (Pubitemid 27216699)
8. Hruska-Hageman AM, Benson CJ, Leonard AS, Price MP, Welsh MJ. PSD-95 and Lin-7b interact with acid-sensing ion channel-3 and have opposite effects on H+-gated current. J Biol Chem 279: 46962-46968, 2004.
9. Jugloff DGM, Khanna R, Schlichter LC, Jones OT. Internalization of the Kv1.4 potassium channel is suppressed by clustering interactions with PSD-95. J Biol Chem 275: 1357-1364, 2000. (Pubitemid 30051193)
10. Khakh BS, Lester HA. Dynamic selectivity filters in ion channels. Neuron 23: 653-658, 1999.
11. Kuo A, Gulbis JM, Antcliff JF, Rahman T, Lowe ED, Zimmer J, Cuthbertson J, Ashcroft FM, Ezaki T, Doyle DA. Crystal structure of the potassium channel KirBac1.1 in the closed state. Science 300: 1922-1926, 2003.
12. Lee S, Fan S, Makarova O, Straight S, Margolis B. A novel and conserved protein-protein interaction domain of mammalian Lin-2/CASK binds and recruits SAP97 to the lateral surface of epithelia. Mol Cell Biol 22: 1778-1791, 2002. (Pubitemid 34174995)
13. Le Maout S, Welling PA, Brejon M, Olsen O, Merot J. Basolateral membrane expression of a K+ channel, Kir 2.3, is directed by a cytoplasmic COOH-terminal domain. Proc Natl Acad Sci USA 98: 10475-10480, 2001. (Pubitemid 32803044)
14. Leonoudakis D, Conti LR, Anderson S, Radeke CM, McGuire LM, Adams ME, Froehner SC, Yates JR, III, Vandenberg CA. Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2. x)-associated proteins. J Biol Chem 279: 22331-22346, 2004. (Pubitemid 38679430)
15. Leonoudakis D, Conti LR, Radeke CM, McGuire LM, Vandenberg CA. A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels. J Biol Chem 279: 19051-19063, 2004. (Pubitemid 38623336)
16. Leonoudakis D, Mailliard W, Wingerd K, Clegg D, Vandenberg C. Inward rectifier potassium channel Kir2.2 is associated with synapse-associated protein SAP97. J Cell Sci 114: 987-998, 2001. (Pubitemid 32266269)
17. Lin Y, Skeberdis VA, Francesconi A, Bennett MVL, Zukin RS. Postsynaptic density protein-95 regulates NMDA channel gating and surface expression. J Neurosci 24: 10138-10148, 2004. (Pubitemid 39492039)
18. Lopatin AN, Nichols CG. Inward rectifiers in the heart: an update on I(K1). J Mol Cell Cardiol 33: 625-638, 2001.
19. Maguy A, Hebert TE, Nattel S. Involvement of lipid rafts and caveolae in cardiac ion channel function. Cardiovasc Res 69: 798-807, 2006. (Pubitemid 43227978)
20. Melnyk P, Zhang L, Shrier A, Nattel S. Differential distribution of Kir2.1 and Kir23 subunits in canine atrium and ventricle. Am J Physiol Heart Circ Physiol 283: H1123-H1133, 2002.
21. Munoz V, Vaidyanathan R, Tolkacheva EG, Dhamoon AS, Taffet SM, Anumonwo JM. Kir2.3 isoform confers pH sensitivity to heteromeric Kir2.1/Kir23 channels in HEK293 cells. Heart Rhythm 4: 487-496, 2007. (Pubitemid 46610405)
22. Murata M, Buckett PD, Zhou J, Brunner M, Folco E, Koren G. SAP97 interacts with Kv1.5 in heterologous expression systems. Am J Physiol Heart Circ Physiol 281: H2575-H2584, 2001. (Pubitemid 34003444)
23. Nakagawa T, Futai K, Lashuel HA, Lo I, Okamoto K, Walz T, Hayashi Y, Sheng M. Quaternary structure, protein dynamics, and synaptic function of SAP97 controlled by L27 domain interactions. Neuron 44: 453-467, 2004. (Pubitemid 39423347)
24. Nehring RB, Wischmeyer E, Doring F, Veh RW, Sheng M, Karschin A. Neuronal inwardly rectifying K(+) channels differentially couple to PDZ proteins of the PSD-95/SAP90 family. J Neurosci 20: 156-162, 2000. (Pubitemid 30220502)
25. Noujaim SF, Pandit SV, Berenfeld O, Vikstrom K, Cerrone M, Mironov S, Zugermayr M, Lopatin AN, Jalife J. Up-regulation of the inward rectifier K+ current (I K1) in the mouse heart accelerates and stabilizes rotors. J Physiol 578: 315-326, 2007. (Pubitemid 44971128)
26. Olsen O, Liu H, Wade JB, Merot J, Welling PA. Basolateral membrane expression of the Kir 2.3 channel is coordinated by PDZ interaction with Lin-7/CASK complex. Am J Physiol Cell Physiol 282: C183-C195, 2002.
27. Pegan S, Arrabit C, Zhou W, Kwiatkowski W, Collins A, Slesinger PA, Choe S. Cytoplasmic domain structures of Kir2.1 and Kir31 show sites for modulating gating and rectification. Nature Neurosci 8: 279-287, 2005. (Pubitemid 40300184)
28. Priori SG, Pandit SV, Rivolta I, Berenfeld O, Ronchetti E, Dhamoon A, Napolitano C, Anumonwo J, di Barletta MR, Gudapakkam S, Bosi G, Stramba-Badiale M, Jalife J. A novel form of short QT syndrome (SQT3) is caused by a mutation in the KCNJ2 gene. Circ Res 96: 800-807, 2005. (Pubitemid 40559520)
29. Rose J, Armoundas AA, Tian Y, DiSilvestre D, Burysek M, Halperin V, O'Rourke B, Kass DA, Marban E, Tomaselli GF. Molecular correlates of altered expression of potassium currents in failing rabbit myocardium. Am J Physiol Heart Circ Physiol 288: H2077-H2087, 2005.
30. Sampson LJ, Leyland ML, Dart C. Direct interaction between the actin-binding protein filamin-A and the inwardly rectifying potassium channel, Kir2.1. J Biol Chem 278: 41988-41997, 2003. (Pubitemid 37310462)
31. Sans N, Racca C, Petralia RS, Wang YX, McCallum J, Wenthold RJ. Synapse-associated protein 97 selectively associates with a subset of AMPA receptors early in their biosynthetic pathway. J Neurosci 21: 7506-7516, 2001. (Pubitemid 32904949)
32. Sheng M, Sala C. PDZ domains and the organization of supramolecular complexes. Annu Rev Neurosci 24: 1-29, 2001. (Pubitemid 32695221)
33. Shikano S, Coblitz B, Sun H, Li M. Genetic isolation of transport signals directing cell surface expression. Nature Cell Biology 7: 985-992, 2005. (Pubitemid 41486272)
34. Shyng SL, Sha Q, Ferrigni T, Lopatin AN, Nichols CG. Depletion of intracellular polyamines relieves inward rectification of potassium channels. Proc Natl Acad Sci USA 93: 12014-12019, 1996. (Pubitemid 26347240)
35. Stanfield PR, Nakajima S, Nakajima Y. Constitutively active and G-protein coupled inward rectifier K+ channels: Kir2.0 and Kir30. Rev Physiol Biochem Pharmacol 145: 47-179, 2002.
36. Tiffany AM, Manganas LN, Kim E, Hsueh YP, Sheng M, Trimmer JS. PSD-95 and SAP97 exhibit distinct mechanisms for regulating K+ channel surface expression and clustering. J Cell Biol 148: 147-158, 2000. (Pubitemid 30046789)
37. Wang Z, Yue L, White M, Pelletier G, Nattel S. Differential distribution of inward rectifier potassium channel transcripts in human atrium versus ventricle. Circulation 98: 2422-2428, 1998. (Pubitemid 28549786)
38. Weigel A, Schild D, Zeug A. Resolution in the ApoTome and the confocal laser scanning microscope: comparison. J Biomed Opt 14: 014022, 2009.
39. Xia M, Jin Q, Bendahhou S, He Y, Larroque MM, Chen Y, Zhou Q, Yang Y, Liu Y, Liu B, Zhu Q, Zhou Y, Lin J, Liang B, Li L, Dong X, Pan Z, Wang R, Wan H, Qiu W, Xu W, Eurlings P, Barhanin J, Chen YA. Kir2.1 gain-of-function mutation underlies familial atrial fibrillation. Biochem Biophys Res Commun 332: 1012-1019, 2005. (Pubitemid 40798187)
40. Zhu G, Chanchevalap S, Cui N, Jiang C. Effects of intra- and extracellular acidifications on single channel Kir2.3 currents. J Physiol (Lond) 516: 699-710, 1999. (Pubitemid 29201896)