Urinary excretion of endothelin receptors ETA and ETB in hypertensive patients and normotensive subjects

Kidney and Blood Pressure Research

Volumn 32, Issue 4, 2009, Pages 293-303

  Karram, Tony ^a   Khamaisi, Mogher ^a   Bishara, Bishara ^a   Ramadan, Rawi ^a   Nitecki, Samy ^a   Ben Izhak, Ofer ^a   Meretyk, Shimon ^a   Winaver, Joseph ^a   Heyman, Samuel N ^b   Hoffman, Aaron ^a   Abassi, Zaid ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

Endothelin; ETA receptors; ETB receptors; Urine

Indexed keywords

ENDOTHELIN 1; ENDOTHELIN CONVERTING ENZYME; ENDOTHELIN RECEPTOR; ENDOTHELIN RECEPTOR TYPE A; ENDOTHELIN RECEPTOR TYPE B; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BLOOD PRESSURE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; HYPERTENSION; IMMUNOREACTIVITY; KIDNEY CONCENTRATING CAPACITY; KIDNEY PARENCHYMA; MALE; MICTURITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; URINALYSIS; URINARY EXCRETION; URINARY TRACT; URINE;

BLOTTING, WESTERN; CREATININE; FEMALE; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HUMANS; HYPERTENSION; IMMUNOPRECIPITATION; KIDNEY; KIDNEY CORTEX; KIDNEY MEDULLA; MALE; MIDDLE AGED; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; REGRESSION ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRICHLOROACETIC ACID;

EID: 70349608361     PISSN: 14204096     EISSN: None     Source Type: Journal    
DOI: 10.1159/000243053     Document Type: Article

References (48)

1. Webb DJ, Monge JC, Rabelink TJ, Yanagisawa M: Endothelin: new discoveries and rapid progress in the clinic. Trends Pharmacol Sci 1988; 19: 5-8.
2. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y, Goto K, Masaki T: A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988; 332: 411-415. (Pubitemid 18090241)
3. Arai H, Hori S, Aramori I, Ohkubo H, Nakanishi S: Cloning and expression of a cDNA encoding an endothelin receptor. Nature 1990; 348: 730-732. (Pubitemid 120015147)
4. Kohan DE: Endothelins in the kidney: physiology and pathophysiology. Am J Kidney Dis 1993; 22: 493-510.
5. Marsen TA, Schramek H, Dunn MJ: Renal actions of endothelin: linking cellular signaling pathways to kidney disease. Kidney Int 1994; 45: 336-344.
6. Rubanyi GM, Polokoff MA: Endothelins: molecular biology, biochemistry, pharmacology, physiology and pathophysiology. Pharm Rev 1994; 46: 325-415.
7. Sakurai T, Yanagisawa M, Takuwa Y, Miyazaki H, Kimura S, Goto K, Masaki T: Cloning of a cDNA encoding a non-isopeptideselective subtype of the endothelin receptor. Nature 1990; 348: 732-735.
8. Tirapelli CR, Casolari DA, Yogi A, Montezano AC, Tostes RC, Legros E, D'Orléans- Juste P, de Oliveira AM: Functional characterization and expression of endothelin receptors in rat carotid artery: involvement of nitric oxide, a vasodilator prostanoid and the opening of K+ channels in ETB-induced relaxation. Br J Pharmacol 2005; 146: 903-912.
9. Schneider MP, Boesen EI, Pollock DM: Contrasting actions of endothelin ET(A) and ET(B) receptors in cardiovascular disease. Annu Rev Pharmacol Toxicol 2007; 47: 731-759.
10. Wendel M, Knels L, Kummer W, Koch T: Distribution of endothelin receptor subtypes ET A and ET B in the rat kidney. J Histochem Cytochem 2006; 54: 1193-1203.
11. Kitamura K, Tanaka T, Kato J, Ogawa T, Eto T, Tanaka K: Immunoreactive endothelin in rat inner medulla: marked decrease in spontaneously hypertensive rats. Biochem Biophys Res Commun 1989; 162: 38-44.
12. Markewitz BA, Kohan DE: Role of intrarenal endothelin in the generation and maintenance of hypertension. Miner Electrolyte Metab 1995; 21: 342-352.
13. Abassi ZA, Klein H, Golomb E, Keiser HR: Urinary endothelin: a possible biological marker of renal damage. Am J Hypertens 1993; 6: 1046-1054.
14. Hsieh TJ, Lin SR, Lee YJ, Shin SJ, Lai YH, Hsu CH, Tsai J: Increased renal medullary endothelin-1 synthesis in prehypertensive DOCA- and salt-treated rats. Am J Physiol Renal Physiol 2000; 279:F112-F121.
15. Kohan DE, Padilla E: Osmolar regulation of endothelin-1 production by rat inner medullary collecting duct. J Clin Invest 1993; 91: 1235-1240.
16. Kohan DE: The renal medullary endothelin system in control of sodium and water excretion and systemic blood pressure. Curr Opin Nephrol Hypertens 2006; 15: 34-40.
17. Pollock DM, Allcock GH, Krishnan A, Dayton BD, Pollock JS: Upregulation of endothelin B receptors in kidneys of DOCA-salt hypertensive rats. Am J Physiol Renal Physiol 2000; 278:F279-F286.
18. Nambi P, Pullen M, Wu HL, Aiyar N, Ohlstein EH, Edwards RM: Identification of endothelin receptor subtypes in human renal cortex and medula using subtype-selective ligands. Endocrinology 1993; 131: 1081-1086.
19. Khamaisi M, Raz I, Shilo V, Shina A, Rosenberger C, Dahan R, Abassi Z, Meidan R, Lecht S, Heyman SN: Diabetes and radiocontrast media increase endothelin converting enzyme-1 in the kidney. Kidney Int 2008; 74: 91-100.
20. Goetz KL, Wang BC, Madwed JB, Zhu JL, Leadley RJ Jr: Cardiovascular, renal, and endocrine responses to intravenous endothelin in conscious dogs. Am J Physiol 1988; 255: R1064-R1068.
21. Kohan DE: Endothelins in the normal and diseased kidney. Am J Kidney Dis 1997; 29: 2-26.
22. Ge Y, Bagnall A, Stricklett PK, Strait K, Webb DJ, Kotelevtsev Y, Kohan DE: Collecting duct-specific knockout of the endothelin B receptor causes hypertension and sodium retention. Am J Physiol Renal Physiol 2006; 291:F1274-F1280.
23. Gariepy CE, Ohuchi T, Williams SC, Richardson JA, Yanagisawa M: Salt-sensitive hypertension in endothelin-B receptor-deficient rats. J Clin Invest 2000; 105: 925-933.
24. Hoffman A, Grossman E, Goldstein DS, Gill JR Jr, Keiser HR: Urinary excretion rate of endothelin-1 in patients with essential hypertension and salt sensitivity. Kidney Int 1994; 45: 556-560.
25. Abassi ZA, Tate JE, Golomb E, Keiser HR: Role of neutral endopeptidase in the metabolism of endothelin. Hypertension 1992; 20: 89-95.
26. Abassi Z, Golomb E, Keiser HR: Neutral endopeptidase inhibition increases the urinary excretion and plasma levels of endothelin. Metabolism 1992; 41: 683-685.
27. Francis BN, Abassi Z, Heyman S, Winaver J, Hoffman A: Differential regulation of ET A and ET B in the renal tissue of rats with compensated and decompensated heart failure. J Cardiovasc Pharmacol 2004; 44(suppl 1): S362-S365.
28. Naicker S, Gathiram P, Naidoo S, Nadar A, Müller-Esterl W, Bhoola KD: Endothelin-1 and endothelin receptor status in kidney transplants undergoing acute rejection. Immunopharmacology 1999; 44: 67-74.
29. Kanno K, Sasaki S, Hirata Y, Ishikawa S, Fushimi K, Nakanishi S, Bichet DG, Marumo F: Urinary excretion of aquaporin-2 in patients with diabetes insipidus. N Engl J Med 1995; 332: 1540-1545.
30. Passero CJ, Mueller GM, Rondon-Berrios H, Tofovic SP, Hughey RP, Kleyman TR: Plasmin activates epithelial Na+ channels by cleaving the gamma subunit. J Biol Chem 2008; 26: 36586-36591.
31. Roos M, Soskic V, Poznanovic S, Godovac- Zimmermann J: Post-translational modifications of endothelin receptor B from bovine lungs analyzed by mass spectrometry. J Biol Chem 1998; 273: 924-931.
32. Abassi ZA, Brodsky S, Karram T, Dobkin I, Winaver J, Hoffman A: Temporal changes in natriuretic and antinatriuretic systems after closure of a large arteriovenous fistula. Cardiovasc Res 2001; 15: 567-576.
33. Pekonen F, Nyman T, Ammala M, Rutanen EM: Decreased expression of messenger RNAs encoding endothelin receptors and neutral endopeptidase 24.11 in endometrial cancer. Br J Cancer 1995; 71: 59-63.
34. Kubota T, Taguchi M, Kamada S, Imai T, Hirata Y, Marumo F, Aso T: Endothelin synthesis and receptors in human endometrium throughout the normal menstrual cycle. Hum Reprod 1995; 10: 2204-2208.
35. Chow LH, Subramanian S, Nuovo GJ, Miller F, Nord EP: Endothelin receptor mRNA expression in renal medulla identified by in situ RT-PCR. Am J Physiol 1995; 269:F449-F457.
36. Takemoto F, Uchida S, Ogata E, Kurokawa K: Endothelin-1 and endothelin-3 binding to rat nephrons. Am J Physiol 1993; 264:F827-F832.
37. Terada Y, Tomita K, Nonoguchi H, Marumo F: Different localization of two types of endothelin receptor mRNA in microdissected rat nephron segments using reverse transcription and polymerase chain reaction assay. J Clin Invest 1992; 90: 107-112.
38. Cernacek P, Legault L, Stewart DJ, Levy M: Specific endothelin binding sites in renal medullary collecting duct cells: lack of interaction with ANP binding and cGMP signalling. Can J Physiol Pharmacol 1992; 70: 1167-1174.
39. Kohan DE, Hughes AK, Perkins S: Characterization of endothelin receptors in the inner medullary collecting duct of the rat. J Biol Chem 1992; 267: 12336-12340.
40. Kohan DE, Padilla E: Endothelin-1 is an autocrine factor in rat inner medullary collecting ducts. Am J Physiol 1992; 263:F607-F612.
41. Rosenberger C, Khamaisi M, Goldfarb M, Shina A, Shilo V, Zilbertrest F, Rosen S, Heyman SN: Acute kidney injury in the diabetic rat: studies in the isolated perfused and intact kidney. Am J Nephrol 2008; 28: 831-839.
42. Langenstroer P, Tang R, Divish B, Opgenorth T, Shapiro E, Lepor H: Endothelins in canine genitourinary tissues. J Urology 1997; 157: 1044-1048.
43. Mumtaz FH, Dashwood MR, Thompson CS, Sullivan ME, Mikhailidis DP, Morgan RJ: Increased expression of endothelin B receptors in the diabetic rabbit urinary bladder: functional relevance. Br J Urol Int 1999; 83: 113-122.
44. Abassi ZA, Ellahham S, Winaver J, Hoffmann A: The intrarenal endothelin system and hypertension. News Physiol Sci 2001; 16: 152-156.
45. Ahn D, Ge Y, Stricklett PK, Gill P, Taylor D, Hughes AK, Yanagisawa M, Miller L, Nelson RD, Kohan DE: Collecting duct-specific knockout of endothelin-1 causes hypertension and sodium retention. J Clin Invest 2004; 114: 504-511.
46. Kitamura K, Tanaka T, Kato J, Eto T, Tanaka K: Regional distribution of immunoreactive endothelin in porcine tissue: abundance in inner medulla of kidney. Biochem Biophys Res Commun 1989; 161: 348-352.
47. Hughes AK, Cline RC, Kohan DE: Alterations in renal endothelin production in the spontaneously hypertensive rat. Hypertension 1992; 20: 666-673.
48. Hocher B, Rohmeiss P, Zart R, Diekmann F, Vogt V, Metz D, Fakhury M, Gretz N, Bauer C, Koppenhagen K: Significance of endothelin receptor subtypes in the kidneys of spontaneously hypertensive rats: renal and hemodynamic effects of endothelin receptor antagonists. J Cardiovasc Pharmacol 1995; 26:S470-S472.