Comparative Cognitive and Subjective Side Effects of Immediate-Release Oxycodone in Healthy Middle-Aged and Older Adults

Journal of Pain

Volumn 10, Issue 10, 2009, Pages 1038-1050

  Cherrier, Monique M ^a,b   Amory, John K ^a   Ersek, Mary ^c   Risler, Linda ^d   Shen, Danny D ^e  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d Fred Hutchinson Cancer Research Center   (United States)

^e UNIVERSITY OF WASHINGTON   (United States)

Author keywords

cognition; older adults; Opioid analgesic; oxycodone; pharmacodynamics; pharmacokinetics; side effects

Indexed keywords

OXYCODONE; PLACEBO;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; ATTENTION; CHRONIC PAIN; COGNITION; CONTROLLED STUDY; DRUG EFFECT; DRUG ELIMINATION; DRUG HALF LIFE; DRUG INDUCED HEADACHE; DRUG RELEASE; FLUSHING; HUMAN; HUMAN EXPERIMENT; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; PARESTHESIA; PRURITUS; PUPIL; SIDE EFFECT; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; VERBAL MEMORY; VOMITING; WORKING MEMORY; XEROSTOMIA;

ADMINISTRATION, ORAL; ADULT; AGE FACTORS; AGED; AGING; ATTENTION; COGNITION; COGNITION DISORDERS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG TOXICITY; FEMALE; GERIATRIC ASSESSMENT; HUMANS; MALE; MEMORY DISORDERS; MEMORY, SHORT-TERM; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; OXYCODONE; PAIN; PAIN MEASUREMENT; QUESTIONNAIRES; RISK FACTORS; SINGLE-BLIND METHOD; TREATMENT OUTCOME;

EID: 70349595374     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2009.03.017     Document Type: Article

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