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Volumn 24, Issue 3, 2009, Pages 367-371

Protease-activated receptor-1 regulates cytokine production and induces the suppressor of cytokine signaling-3 in microglia

Author keywords

Inflammation; Microglia; Protease activated receptor 1

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PROTEINASE ACTIVATED RECEPTOR 1; SUPPRESSOR OF CYTOKINE SIGNALING 3; THROMBIN; THROMBIN RECEPTOR ACTIVATING PEPTIDE 6; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; MESSENGER RNA; OLIGOPEPTIDE; SER PHE PHE LEU ARG ASN; SER-PHE-PHE-LEU-ARG-ASN; SOCS3 PROTEIN, RAT; SUPPRESSOR OF CYTOKINE SIGNALING;

EID: 70349574106     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm_00000241     Document Type: Article
Times cited : (19)

References (38)
  • 1
    • 28344436780 scopus 로고    scopus 로고
    • Protease-activated receptors in hemostasis, thrombosis and vascular biology
    • Coughlin SR: Protease-activated receptors in hemostasis, thrombosis and vascular biology. J Thromb Haemost 3: 1800-1814, 2005.
    • (2005) J Thromb Haemost , vol.3 , pp. 1800-1814
    • Coughlin, S.R.1
  • 2
    • 34247388037 scopus 로고    scopus 로고
    • Protease-activated receptor signalling, endocytic sorting and dysregulation in cancer
    • Arora P, Ricks TK and Trejo J: Protease-activated receptor signalling, endocytic sorting and dysregulation in cancer. J Cell Sci 120: 921-928, 2007.
    • (2007) J Cell Sci , vol.120 , pp. 921-928
    • Arora, P.1    Ricks, T.K.2    Trejo, J.3
  • 3
    • 17344365478 scopus 로고    scopus 로고
    • Thrombin perturbs neurite outgrowth and induces apoptotic cell death in enriched chick spinal motoneuron cultures through caspase activation
    • Turgeon VL, Lloyd ED, Wang S, Festoff BW and Houenou LJ: Thrombin perturbs neurite outgrowth and induces apoptotic cell death in enriched chick spinal motoneuron cultures through caspase activation. J Neurosci 18: 6882-6891, 1998.
    • (1998) J Neurosci , vol.18 , pp. 6882-6891
    • Turgeon, V.L.1    Lloyd, E.D.2    Wang, S.3    Festoff, B.W.4    Houenou, L.J.5
  • 4
    • 0034660448 scopus 로고    scopus 로고
    • Potentiation of NMDA receptor function by the serine protease thrombin
    • Gingrich MB, Junge CE, Lyuboslavsky P and Traynelis SF: Potentiation of NMDA receptor function by the serine protease thrombin. J Neurosci 20: 4582-4595, 2000.
    • (2000) J Neurosci , vol.20 , pp. 4582-4595
    • Gingrich, M.B.1    Junge, C.E.2    Lyuboslavsky, P.3    Traynelis, S.F.4
  • 5
    • 29044433625 scopus 로고    scopus 로고
    • Increase in proliferation and gliogenesis but decrease of early neurogenesis in the rat forebrain shortly after transient global ischemia
    • Pforte C, Henrich-Noack P, Baldauf K and Reymann KG: Increase in proliferation and gliogenesis but decrease of early neurogenesis in the rat forebrain shortly after transient global ischemia. Neuroscience 136: 1133-1146, 2005.
    • (2005) Neuroscience , vol.136 , pp. 1133-1146
    • Pforte, C.1    Henrich-Noack, P.2    Baldauf, K.3    Reymann, K.G.4
  • 6
    • 33847663776 scopus 로고    scopus 로고
    • Protease-activated receptor-1 induces generation of new microglia in the dentate gyrus of traumatised hippocampal slice cultures
    • Laskowski A, Reiser G and Reymann KG: Protease-activated receptor-1 induces generation of new microglia in the dentate gyrus of traumatised hippocampal slice cultures. Neurosci Lett 415: 17-21, 2007.
    • (2007) Neurosci Lett , vol.415 , pp. 17-21
    • Laskowski, A.1    Reiser, G.2    Reymann, K.G.3
  • 7
    • 32644480452 scopus 로고    scopus 로고
    • Focal ischemia induces expression of protease-activated receptor1 (PAR1) and PAR3 on microglia and enhances PAR4 labeling in the penumbra
    • Henrich-Noack P, Riek-Burchardt M, Baldauf K, Reiser G and Reymann KG: Focal ischemia induces expression of protease-activated receptor1 (PAR1) and PAR3 on microglia and enhances PAR4 labeling in the penumbra. Brain Res 1070: 232-241, 2006.
    • (2006) Brain Res , vol.1070 , pp. 232-241
    • Henrich-Noack, P.1    Riek-Burchardt, M.2    Baldauf, K.3    Reiser, G.4    Reymann, K.G.5
  • 9
    • 0034053127 scopus 로고    scopus 로고
    • The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations
    • Striggow F, Riek M, Breder J, Henrich-Noack P, Reymann KG and Reiser G: The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations. Proc Natl Acad Sci USA 97: 2264-2269, 2000.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 2264-2269
    • Striggow, F.1    Riek, M.2    Breder, J.3    Henrich-Noack, P.4    Reymann, K.G.5    Reiser, G.6
  • 10
    • 0029012029 scopus 로고
    • Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults
    • Vaughan PJ, Pike CJ, Cotman CW and Cunningham DD: Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults. J Neurosci 15: 5389-5401, 1995.
    • (1995) J Neurosci , vol.15 , pp. 5389-5401
    • Vaughan, P.J.1    Pike, C.J.2    Cotman, C.W.3    Cunningham, D.D.4
  • 11
    • 0029914487 scopus 로고    scopus 로고
    • Thrombin attenuates neuronal cell death and modulates astrocyte reactivity induced by beta-amyloid in vitro
    • Pike CJ, Vaughan PJ, Cunningham DD and Cotman CW: Thrombin attenuates neuronal cell death and modulates astrocyte reactivity induced by beta-amyloid in vitro. J Neurochem 66: 1374-1382, 1996.
    • (1996) J Neurochem , vol.66 , pp. 1374-1382
    • Pike, C.J.1    Vaughan, P.J.2    Cunningham, D.D.3    Cotman, C.W.4
  • 12
    • 0037035562 scopus 로고    scopus 로고
    • Thrombin induces IL-10 production in microglia as a negative feedback regulator of TNF-alpha release
    • Kim KY, Kim MY, Choi HS, Jin BK, Kim SU and Lee YB: Thrombin induces IL-10 production in microglia as a negative feedback regulator of TNF-alpha release. Neuroreport 13: 849-852, 2002.
    • (2002) Neuroreport , vol.13 , pp. 849-852
    • Kim, K.Y.1    Kim, M.Y.2    Choi, H.S.3    Jin, B.K.4    Kim, S.U.5    Lee, Y.B.6
  • 14
    • 0033822556 scopus 로고    scopus 로고
    • Thrombin-induced activation of cultured rodent microglia
    • Möller T, Hanisch UK and Ransom BR: Thrombin-induced activation of cultured rodent microglia. J Neurochem 75: 1539-1547, 2000.
    • (2000) J Neurochem , vol.75 , pp. 1539-1547
    • Möller, T.1    Hanisch, U.K.2    Ransom, B.R.3
  • 15
    • 0038383698 scopus 로고    scopus 로고
    • Thrombin-induced microglial activation produces degeneration of nigral dopaminergic neurons in vivo
    • Choi SH, Joe EH, Kim SU and Jin BK: Thrombin-induced microglial activation produces degeneration of nigral dopaminergic neurons in vivo. J Neurosci 23: 5877-5886, 2003.
    • (2003) J Neurosci , vol.23 , pp. 5877-5886
    • Choi, S.H.1    Joe, E.H.2    Kim, S.U.3    Jin, B.K.4
  • 16
    • 0034730753 scopus 로고    scopus 로고
    • Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-kappa B
    • Ryu J, Pyo H, Jou I and Joe E: Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-kappa B. J Biol Chem 275: 29955-29959, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 29955-29959
    • Ryu, J.1    Pyo, H.2    Jou, I.3    Joe, E.4
  • 18
    • 28244490583 scopus 로고    scopus 로고
    • Unraveling thrombin's true microglia-activating potential: Markedly disparate profiles of pharmaceutical-grade and commercial-grade thrombin preparations
    • Weinstein JR, Hong S, Kulman JD, Bishop C, Kuniyoshi J, Andersen H, Ransom BR, Hanisch UK and Möller T: Unraveling thrombin's true microglia-activating potential: markedly disparate profiles of pharmaceutical-grade and commercial-grade thrombin preparations. J Neurochem 95: 1177-1187, 2005.
    • (2005) J Neurochem , vol.95 , pp. 1177-1187
    • Weinstein, J.R.1    Hong, S.2    Kulman, J.D.3    Bishop, C.4    Kuniyoshi, J.5    Andersen, H.6    Ransom, B.R.7    Hanisch, U.K.8    Möller, T.9
  • 19
    • 0032524997 scopus 로고    scopus 로고
    • Microglia are more efficient than astrocytes in antigen processing and in Th1 but not Th2 cell activation
    • Aloisi F, Ria F, Penna G and Adorini L: Microglia are more efficient than astrocytes in antigen processing and in Th1 but not Th2 cell activation. J Immunol 160: 4671-4680, 1998.
    • (1998) J Immunol , vol.160 , pp. 4671-4680
    • Aloisi, F.1    Ria, F.2    Penna, G.3    Adorini, L.4
  • 20
    • 0024595042 scopus 로고
    • Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill
    • Hansen MB, Nielsen K and Berg K: Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J Immunol Methods 119: 203-210, 1989.
    • (1989) J Immunol Methods , vol.119 , pp. 203-210
    • Hansen, M.B.1    Nielsen, K.2    Berg, K.3
  • 22
    • 24744442778 scopus 로고    scopus 로고
    • Thrombin-mediated IL-10 up-regulation involves protease-activated receptor(PAR)-1 expression in human mononuclear leukocytes
    • Naldini A, Bernini C, Pucci A and Carraro F: Thrombin-mediated IL-10 up-regulation involves protease-activated receptor(PAR)-1 expression in human mononuclear leukocytes. J Leukoc Biol 78: 736-744, 2005.
    • (2005) J Leukoc Biol , vol.78 , pp. 736-744
    • Naldini, A.1    Bernini, C.2    Pucci, A.3    Carraro, F.4
  • 24
    • 0030823980 scopus 로고    scopus 로고
    • Proteinase-activated receptors: Structural requirements for activity, receptor cross-reactivity, and receptor selectivity of receptor-activating peptides
    • Hollenberg MD, Saifeddine M, al-Ani B and Kawabata A: Proteinase-activated receptors: structural requirements for activity, receptor cross-reactivity, and receptor selectivity of receptor-activating peptides. Can J Physiol Pharmacol 75: 832-841, 1997.
    • (1997) Can J Physiol Pharmacol , vol.75 , pp. 832-841
    • Hollenberg, M.D.1    Saifeddine, M.2    al-Ani, B.3    Kawabata, A.4
  • 25
    • 1842689861 scopus 로고    scopus 로고
    • Thrombin induces suppressor of cytokine signaling 3 expression in brain microglia via protein kinase Cdelta activation
    • Yang MS, Lee J, Ji KA, Min KJ, Lee MA, Jou I and Joe E: Thrombin induces suppressor of cytokine signaling 3 expression in brain microglia via protein kinase Cdelta activation. Biochem Biophys Res Commun 317: 811-816, 2004.
    • (2004) Biochem Biophys Res Commun , vol.317 , pp. 811-816
    • Yang, M.S.1    Lee, J.2    Ji, K.A.3    Min, K.J.4    Lee, M.A.5    Jou, I.6    Joe, E.7
  • 26
    • 3242657297 scopus 로고    scopus 로고
    • SOCS: Role in inflammation, allergy and homeostasis
    • Elliott J and Johnston JA: SOCS: role in inflammation, allergy and homeostasis. Trends Immunol 25: 434-440, 2004.
    • (2004) Trends Immunol , vol.25 , pp. 434-440
    • Elliott, J.1    Johnston, J.A.2
  • 28
    • 33644898880 scopus 로고    scopus 로고
    • Upregulation of protease-activated receptor-1 in astrocytes in Parkinson disease: Astrocyte-mediated neuroprotection through increased levels of glutathione peroxidase
    • Ishida Y, Nagai A, Kobayashi S and Kim SU: Upregulation of protease-activated receptor-1 in astrocytes in Parkinson disease: astrocyte-mediated neuroprotection through increased levels of glutathione peroxidase. J Neuropathol Exp Neurol 65: 66-77, 2006.
    • (2006) J Neuropathol Exp Neurol , vol.65 , pp. 66-77
    • Ishida, Y.1    Nagai, A.2    Kobayashi, S.3    Kim, S.U.4
  • 29
    • 1342306711 scopus 로고    scopus 로고
    • Trimethyltin-induced differential expression of PAR subtypes in reactive astrocytes of the rat hippocampus
    • Pompili E, Nori SL, Geloso MC, Guadagni E, Corvino V, Michetti F and Fumagalli L: Trimethyltin-induced differential expression of PAR subtypes in reactive astrocytes of the rat hippocampus. Mol Brain Res 122: 93-98, 2004.
    • (2004) Mol Brain Res , vol.122 , pp. 93-98
    • Pompili, E.1    Nori, S.L.2    Geloso, M.C.3    Guadagni, E.4    Corvino, V.5    Michetti, F.6    Fumagalli, L.7
  • 30
    • 33748134817 scopus 로고    scopus 로고
    • PAR-1 upregulation by trimethyltin and lipopolysaccharide in cultured rat astrocytes
    • Pompili E, Fabrizi C and Fumagalli L: PAR-1 upregulation by trimethyltin and lipopolysaccharide in cultured rat astrocytes. Int J Mol Med 18: 33-39, 2006.
    • (2006) Int J Mol Med , vol.18 , pp. 33-39
    • Pompili, E.1    Fabrizi, C.2    Fumagalli, L.3
  • 31
    • 39149117362 scopus 로고    scopus 로고
    • Immunosuppression after traumatic or ischemic CNS damage: It is neuroprotective and illuminates the role of microglial cells
    • Hailer NP: Immunosuppression after traumatic or ischemic CNS damage: it is neuroprotective and illuminates the role of microglial cells. Prog Neurobiol 84: 211-233, 2008.
    • (2008) Prog Neurobiol , vol.84 , pp. 211-233
    • Hailer, N.P.1
  • 32
    • 34548360527 scopus 로고    scopus 로고
    • Exacerbation of dopaminergic terminal damage in a mouse model of Parkinson's disease by the G-protein-coupled receptor protease-activated receptor 1
    • Hamill CE, Caudle WM, Richardson JR, Yuan H, Pennell K, Greene JG, Miller GW and Traynelis SF: Exacerbation of dopaminergic terminal damage in a mouse model of Parkinson's disease by the G-protein-coupled receptor protease-activated receptor 1. Mol Pharmacol 72: 653-664, 2007.
    • (2007) Mol Pharmacol , vol.72 , pp. 653-664
    • Hamill, C.E.1    Caudle, W.M.2    Richardson, J.R.3    Yuan, H.4    Pennell, K.5    Greene, J.G.6    Miller, G.W.7    Traynelis, S.F.8
  • 33
    • 0035799374 scopus 로고    scopus 로고
    • Anti-inflammatory, antithrombotic, and neuroprotective effects of activated protein C in a murine model of focal ischemic stroke
    • Shibata M, Kumar SR, Amar A, Fernandez JA, Hofman F, Griffin JH and Zlokovic BV: Anti-inflammatory, antithrombotic, and neuroprotective effects of activated protein C in a murine model of focal ischemic stroke. Circulation 103: 1799-1805, 2001.
    • (2001) Circulation , vol.103 , pp. 1799-1805
    • Shibata, M.1    Kumar, S.R.2    Amar, A.3    Fernandez, J.A.4    Hofman, F.5    Griffin, J.H.6    Zlokovic, B.V.7
  • 36
    • 17844370507 scopus 로고    scopus 로고
    • Cytokine-mediated inflammation, tumorigenesis, and disease-associated JAK/STAT/SOCS signaling circuits in the CNS
    • Campbell IL: Cytokine-mediated inflammation, tumorigenesis, and disease-associated JAK/STAT/SOCS signaling circuits in the CNS. Brain Res Rev 48: 166-177, 2005.
    • (2005) Brain Res Rev , vol.48 , pp. 166-177
    • Campbell, I.L.1
  • 37
    • 0037097509 scopus 로고    scopus 로고
    • Involvement of suppressor of cytokine signaling-3 as a mediator of the inhibitory effects of IL-10 on lipopolysaccharide-induced macrophage activation
    • Berlato C, Cassatella MA, Kinjyo I, Gatto L, Yoshimura A and Bazzoni F: Involvement of suppressor of cytokine signaling-3 as a mediator of the inhibitory effects of IL-10 on lipopolysaccharide-induced macrophage activation. J Immunol 168: 6404-6411, 2002.
    • (2002) J Immunol , vol.168 , pp. 6404-6411
    • Berlato, C.1    Cassatella, M.A.2    Kinjyo, I.3    Gatto, L.4    Yoshimura, A.5    Bazzoni, F.6
  • 38
    • 33646581368 scopus 로고    scopus 로고
    • Divergent mechanisms utilized by SOCS3 to mediate interleukin-10 inhibition of tumor necrosis factor alpha and nitric oxide production by macrophages
    • Qasimi P, Ming-Lum A, Ghanipour A, Ong CJ, Cox ME, Ihle J, Cacalano N, Yoshimura A and Mui AL: Divergent mechanisms utilized by SOCS3 to mediate interleukin-10 inhibition of tumor necrosis factor alpha and nitric oxide production by macrophages. J Biol Chem 281: 6316-6324, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 6316-6324
    • Qasimi, P.1    Ming-Lum, A.2    Ghanipour, A.3    Ong, C.J.4    Cox, M.E.5    Ihle, J.6    Cacalano, N.7    Yoshimura, A.8    Mui, A.L.9


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