Founder mutations account for the majority of BRCA1-attributable hereditary breast/ovarian cancer cases in a population from Tuscany, Central Italy

Breast Cancer Research and Treatment

Volumn 117, Issue 3, 2009, Pages 497-504

  Papi, Laura ^a   Putignano, Anna Laura ^a   Congregati, Caterina ^a   Zanna, Ines ^b   Sera, Francesco ^b   Morrone, Doralba ^b   Falchetti, Mario ^c   Turco, Marco Rosselli Del ^d   Ottini, Laura ^c   Palli, Domenico ^b   Genuardi, Maurizio ^a,e  

^a UNIVERSITY OF FLORENCE   (Italy)

^b Scientific Institute of Tuscany   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d PRESA   (Italy)

^e Fiorgen Foundation for Pharmacogenomics   (Italy)

Author keywords

BRCA1; BRCA2; Founder mutation; Hereditary breast ovarian cancer; Male breast cancer

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

ARTICLE; BREAST CANCER; DENATURING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; DISEASE ASSOCIATION; FAMILIAL CANCER; FAMILY; FEMALE; GENE MUTATION; GENETIC ASSOCIATION; HAPLOTYPE; HUMAN; ITALY; MALE; NUCLEOTIDE SEQUENCE; OVARY CANCER; PRIORITY JOURNAL;

ADULT; AGED; BREAST NEOPLASMS; BREAST NEOPLASMS, MALE; DNA MUTATIONAL ANALYSIS; FEMALE; FOUNDER EFFECT; GENES, BRCA1; HAPLOTYPES; HUMANS; ITALY; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; PEDIGREE;

EID: 70349573778     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-008-0190-3     Document Type: Article

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