Multiple founder effects and geographical clustering of BRCA1 and BRCA2 families in Finland

European Journal of Human Genetics

Volumn 8, Issue 10, 2000, Pages 757-763

  Sarantaus, Laura ^a   Huusko, Pia ^b   Eerola, Hannaleena ^a   Launonen, Virpi ^b   Vehmanen, Paula ^a   Rapakko, Katrin ^b   Gillanders, Elizabeth ^c   Syrjäkoski, Kirsi ^d   Kainu, Tommi ^d   Vahteristo, Pia ^a   Krahe, Ralf ^a   Pääkkönen, Kati ^a   Hartikainen, Jaana ^e   Blomqvist, Carl ^a   Löppönen, Tuija ^b   Holli, Kaija ^f   Ryynänen, Markku ^e   Bützow, Ralf ^a   Borg, Åke ^a   Arver, Brita Wasteson ^g   Holmberg, Eva ^h   Mannermaa, Arto ^e   Kere, Juha ^a   Kallioniemi, Olli Pekka ^d   Winqvist, Robert ^b   Nevanlinna, Heli ^a   more..

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF OULU   (Finland)

^c NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF TAMPERE   (Finland)

^e KUOPIO UNIVERSITY HOSPITAL   (Finland)

^f TAMPERE UNIVERSITY HOSPITAL   (Finland)

^g KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^h UMEÅ UNIVERSITY HOSPITAL   (Sweden)

Author keywords

BRCA1; BRCA2; Breast cancer; Founder mutations; Haplotype; Ovarian cancer

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER INCIDENCE; CANCER SUSCEPTIBILITY; CHROMOSOME 13Q; CHROMOSOME 17Q; DATA ANALYSIS; FAMILY HISTORY; FEMALE; FINLAND; FOUNDER EFFECT; GENE LOCATION; GENE MAPPING; GENE MUTATION; GENETIC ANALYSIS; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; GEOGRAPHIC DISTRIBUTION; HERITABILITY; HETEROZYGOTE DETECTION; HUMAN; MAJOR CLINICAL STUDY; MARKER GENE; MULTIGENE FAMILY; NUCLEIC ACID BASE SUBSTITUTION; ONCOGENE; OVARY CANCER; PHENOTYPE; PRIORITY JOURNAL; RISK ASSESSMENT; STATISTICAL ANALYSIS;

ADULT; AGED; BRCA2 PROTEIN; BREAST NEOPLASMS; FAMILY; FEMALE; FINLAND; FOUNDER EFFECT; GENES, BRCA1; GENOTYPE; HAPLOTYPES; HUMANS; MIDDLE AGED; MUTATION; NEOPLASM PROTEINS; OVARIAN NEOPLASMS; PHENOTYPE; TIME FACTORS; TRANSCRIPTION FACTORS;

FALLOPIA;

EID: 0033772932     PISSN: 10184813     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5200529     Document Type: Article

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