Spatiotemporal regulation of intracellular trafficking of Toll-like receptor 9 by an inhibitory receptor, Ly49Q

Blood

Volumn 114, Issue 8, 2009, Pages 1518-1527

  Yoshizaki, Mariko ^a   Tazawa, Aya ^a   Kasumi, Eiji ^a   Sasawatari, Shigemi ^a   Itoh, Kenji ^b   Dohi, Taeko ^a   Sasazuki, Takehiko ^a   Inaba, Kayo ^c   Makrigiannis, Andrew P ^d   Toyama Sorimachi, Noriko ^a  

^a NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CPG OLIGODEOXYNUCLEOTIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN INHIBITOR; PROTEIN INHIBITOR LY49Q; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG; CPG OLIGONUCLEOTIDE; CPG-OLIGONUCLEOTIDE; CYTOKINE; KLRA17 PROTEIN, MOUSE; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY A; OLIGODEOXYRIBONUCLEOTIDE; SMALL INTERFERING RNA; TLR9 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; ENDOSOME; ENZYME ACTIVATION; LYSOSOME; MACROPHAGE; MOUSE; NATURAL KILLER CELL; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; ANIMAL; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; PROTEIN TRANSPORT; TIME; TISSUE DISTRIBUTION;

ANIMALS; CELLS, CULTURED; CYTOKINES; DENDRITIC CELLS; ENDOSOMES; MACROPHAGES; MICE; MICE, KNOCKOUT; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY A; OLIGODEOXYRIBONUCLEOTIDES; PROTEIN TRANSPORT; RNA, SMALL INTERFERING; TIME FACTORS; TISSUE DISTRIBUTION; TOLL-LIKE RECEPTOR 9;

EID: 70349563374     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-12-192344     Document Type: Article

References (36)

1. Kawai T, Akira S. TLR signaling. Semin Immunol. 2007;19:24-32.
2. Barton GM, Kagan JC, Medzhitov R. Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA. Nat Immunol. 2006;7:49-56. (Pubitemid 41823868)
3. Latz E, Schoenemeyer A, Visintin A, et al. TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat Immunol. 2004;5:190-198. (Pubitemid 38208361)
4. Kim YM, Brinkmann MM, Paquet ME, Ploegh HL. UNC93B1 delivers nucleotide-sensing Toll-like receptors to endolysosomes. Nature. 2008;452: 234-238.
5. Honda K, Ohba Y, Yanai H, et al. Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction. Nature. 2005;434: 1035-1040. (Pubitemid 40586053)
6. Guiducci C, Ott G, Chan JH, et al. Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation. J Exp Med. 2006;203:1999-2008. (Pubitemid 44188473)
7. Toyama-Sorimachi N, Tsujimura Y, Maruya M, et al. Ly49Q, a member of the Ly49 family that is selectively expressed on myeloid lineage cells and involved in regulation of cytoskeletal architecture. Proc Natl Acad Sci U S A. 2004;101: 1016-1021. (Pubitemid 38160576)
8. Makrigiannis AP, Pau AT, Schwartzberg PL, McVicar DW, Beck TW, Anderson SK. A BAC contig map of the Ly49 gene cluster in 129 mice reveals extensive differences in gene content relative to C57BL/6 mice. Genomics. 2002;79: 437-444.
9. Toyama-Sorimachi N, Omatsu Y, Onoda A, et al. Inhibitory NK receptor Ly49Q is expressed on subsets of dendritic cells in a cellular maturation-and cytokine stimulation-dependent manner. J Immunol. 2005;174:4621-4629. (Pubitemid 40504543)
10. Omatsu Y, Iyoda T, Kimura Y, et al. Development of murine plasmacytoid dendritic cells defined by increased expression of an inhibitory NK receptor, Ly49Q. J Immunol. 2005;174:6657-6662.
11. Kamogawa-Schifter Y, Ohkawa J, Namiki S, Arai N, Arai K, Liu Y. Ly49Q defines 2 pDC subsets in mice. Blood. 2005;105:2787-2792.
12. Tai LH, Goulet ML, Belanger S, et al. Positive regulation of plasmacytoid dendritic cell function via Ly49Q recognition of class I MHC. J Exp Med. 2008;205:3187-3199.
13. Doucey MA, Scarpellino L, Zimmer J, et al. Cis association of Ly49A with MHC class I restricts natural killer cell inhibition. Nat Immunol. 2004;5: 328-336. (Pubitemid 38332130)
14. Tanimura N, Saitoh S, Matsumoto F, Akashi-Takamura S, Miyake K. Roles for LPS-dependent interaction and relocation of TLR4 and TRAM in TRIF-signaling. Biochem Biophys Res Commun. 2008;368:94-99.
15. Matsumoto F, Saitoh S, Fukui R, et al. Cathepsins are required for Toll-like receptor 9 responses. Biochem Biophys Res Commun. 2008;367:693-699.
16. Datta SK, Redecke V, Prilliman KR, et al. A subset of Toll-like receptor ligands induces cross-presentation by bone marrow-derived dendritic cells. J Immunol. 2003;170:4102-4110. (Pubitemid 36428173)
17. Rutz M, Metzger J, Gellert T, et al. Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence-and pH-dependent manner. Eur J Immunol. 2004;34:2541-2550. (Pubitemid 39302811)
18. Vyas JM, Kim YM, Artavanis-Tsakonas K, Love JC, Van der Veen AG, Ploegh HL. Tubulation of class II MHC compartments is microtubule dependent and involves multiple endolysosomal membrane proteins in primary dendritic cells. J Immunol. 2007;178:7199-7210. (Pubitemid 46847446)
19. Wehland J, Weber K. Turnover of the carboxy-terminal tyrosine of α-tubulin and means of reaching elevated levels of detyrosination in living cells. J Cell Sci. 1987;88:185-203.
20. Tai LH, Goulet ML, Belanger S, et al. Recognition of H-2Kb by Ly49Q suggests a role for class Ia MHC regulation of plasmacytoid dendritic cell function. Mol Immunol. 2007;44:2638-2646. (Pubitemid 46240325)
21. Boll W, Ohno H, Songyang Z, et al. Sequence requirements for the recognition of tyrosine-based endocytic signals by clathrin AP-2 complexes. EMBO J. 1996;15:5789-5795. (Pubitemid 26375500)
22. Keller P, Simons K. Cholesterol is required for surface transport of influenza virus hemagglutinin. J Cell Biol. 1998;140:1357-1367. (Pubitemid 28152985)
23. Wang LH, Rothberg KG, Anderson RG. Misassembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation. J Cell Biol. 1993;123:1107-1117. (Pubitemid 23352421)
24. Mukhopadhyay A, Funato K, Stahl PD. Rab7 regulates transport from early to late endocytic compartments in Xenopus oocytes. J Biol Chem. 1997;272:13055-13059. (Pubitemid 27216726)
25. Courtneidge SA. Activation of the pp60c-src kinase by middle T antigen binding or by dephosphorylation. EMBO J. 1985;4:1471-1477.
26. Woodman PG, Futter CE. Multivesicular bodies: co-ordinated progression to maturity. Curr Opin Cell Biol. 2008;20:408-414.
27. Harrison RE, Bucci C, Vieira OV, Schroer TA, Grinstein S. Phagosomes fuse with late endosomes and/or lysosomes by extension of membrane protrusions along microtubules: role of Rab7 and RILP. Mol Cell Biol. 2003;23:6494-6506. (Pubitemid 37075761)
28. Racoosin EL, Swanson JA. Macropinosome maturation and fusion with tubular lysosomes in macrophages. J Cell Biol. 1993;121:1011-1020. (Pubitemid 23154262)
29. Hollenbeck PJ, Swanson JA. Radial extension of macrophage tubular lysosomes supported by kinesin. Nature. 1990;346:864-866. (Pubitemid 20272110)
30. Heuser J. Changes in lysosome shape and distribution correlated with changes in cytoplasmic pH. J Cell Biol. 1989;108:855-864. (Pubitemid 19083739)
31. Shiratori T, Miyatake S, Ohno H, et al. Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2. Immunity. 1997;6:583-589. (Pubitemid 27239349)
32. Orr SJ, Morgan NM, Elliott J, et al. CD33 responses are blocked by SOCS3 through accelerated proteasomal-mediated turnover. Blood. 2007;109:1061-1068.
33. Li C, Ge B, Nicotra M, et al. JNK MAP kinase activation is required for MTOC and granule polarization in NKG2D-mediated NK cell cytotoxicity. Proc Natl Acad Sci U S A. 2008;105:3017-3022. (Pubitemid 351723660)
34. Clark R, Griffiths GM. Lytic granules, secretory lysosomes and disease. Curr Opin Immunol. 2003;15:516-521. (Pubitemid 37130191)
35. Cavalli V, Vilbois F, Corti M, et al. The stress-induced MAP kinase p38 regulates endocytic trafficking via the GDI:Rab5 complex. Mol Cell. 2001; 7:421-432. (Pubitemid 32206509)
36. Mace G, Miaczynska M, Zerial M, Nebreda AR. Phosphorylation of EEA1 by p38 MAP kinase regulates μ opioid receptor endocytosis. EMBO J. 2005;24:3235-3246. (Pubitemid 41348698)