메뉴 건너뛰기




Volumn 122, Issue 15, 2009, Pages 1800-1805

Cloning and bioinformatic analysis of lovastatin biosynthesis regulatory gene lovE

Author keywords

Aspergillus; Bioinformatics; Lovastatin

Indexed keywords

GENOMIC DNA; MEVINOLIN; PROTEIN LOVE; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

EID: 70349557870     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2009.15.016     Document Type: Article
Times cited : (11)

References (16)
  • 2
    • 0037233913 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors regulate inflammatory transcription factors in human endothelial and vascular smooth muscle cells
    • Dichtl W, Dulak J, Frick M, Alber HF, Schwarzacher SP, Ares MP, et al. HMG-CoA reductase inhibitors regulate inflammatory transcription factors in human endothelial and vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 2003; 23:58-63.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 58-63
    • Dichtl, W.1    Dulak, J.2    Frick, M.3    Alber, H.F.4    Schwarzacher, S.P.5    Ares, M.P.6
  • 3
    • 0041920695 scopus 로고    scopus 로고
    • Lovastatin induces apoptosis of anaplastic thyroid cancer cells via inhibition of protein geranylgeranylation and de novo protein synthesis
    • Zhong WB, Wang CY, Chang TC, Lee WS. Lovastatin induces apoptosis of anaplastic thyroid cancer cells via inhibition of protein geranylgeranylation and de novo protein synthesis. Endocrinology 2003; 144: 3852-3859.
    • (2003) Endocrinology , vol.144 , pp. 3852-3859
    • Zhong, W.B.1    Wang, C.Y.2    Chang, T.C.3    Lee, W.S.4
  • 4
    • 70349520955 scopus 로고    scopus 로고
    • Effects of lovastatin on proliferation ability and pRb protein expression of MCF-7 cells
    • Zhang P, Mi MT, Wei N, Zhang QY, Zhou Y. Effects of lovastatin on proliferation ability and pRb protein expression of MCF-7 cells. China Public Health (Chin) 2002; 18: 1198.
    • (2002) China Public Health (Chin) , vol.18 , pp. 1198
    • Zhang, P.1    Mi, M.T.2    Wei, N.3    Zhang, Q.Y.4    Zhou, Y.5
  • 5
    • 0037316031 scopus 로고    scopus 로고
    • Integrating transcriptional and metabolite profiles to direct the engineering of lovastatin-producing fungal strains
    • Askenazi M, Driggers EM, Holtzman DA, Norman TC, Lverson S, Zimmer DP, et al. Integrating transcriptional and metabolite profiles to direct the engineering of lovastatin-producing fungal strains. Natl Biotechnol 2003; 21: 150-156.
    • (2003) Natl Biotechnol , vol.21 , pp. 150-156
    • Askenazi, M.1    Driggers, E.M.2    Holtzman, D.A.3    Norman, T.C.4    Lverson, S.5    Zimmer, D.P.6
  • 6
    • 0038058643 scopus 로고    scopus 로고
    • Transformations of cyclic nonaketides by Aspergillus terrus mutants blocked for lovastatin biosynthesis at the lovA and lovC genes
    • Sorensen JL, Auclair K, Kennedy J, Hutchinson CR, Vederas JC. Transformations of cyclic nonaketides by Aspergillus terrus mutants blocked for lovastatin biosynthesis at the lovA and lovC genes. Org Biomol Chem 2003; 1: 50-59.
    • (2003) Org Biomol Chem , vol.1 , pp. 50-59
    • Sorensen, J.L.1    Auclair, K.2    Kennedy, J.3    Hutchinson, C.R.4    Vederas, J.C.5
  • 7
    • 33751092257 scopus 로고    scopus 로고
    • Biosynthesis of lovastatin analogs with a broadly specific acyltransferase
    • Xie X, Watanabe K, Wojcicki WA, Wang CC, Tang Y. Biosynthesis of lovastatin analogs with a broadly specific acyltransferase. Chem Biol 2006; 13: 1161-1169.
    • (2006) Chem Biol , vol.13 , pp. 1161-1169
    • Xie, X.1    Watanabe, K.2    Wojcicki, W.A.3    Wang, C.C.4    Tang, Y.5
  • 8
    • 42549137378 scopus 로고    scopus 로고
    • Lovastatin biosynthetic genes of Aspergillus terreus are expressed differentially in solid-state and in liquid submerged fermentation
    • Barrios-Gonzalez J, Banos JG, Covarrubias AA, Garay-Arroyo A. Lovastatin biosynthetic genes of Aspergillus terreus are expressed differentially in solid-state and in liquid submerged fermentation. Appl Microbiol Biotechnol 2008; 79: 179-186.
    • (2008) Appl Microbiol Biotechnol , vol.79 , pp. 179-186
    • Barrios-Gonzalez, J.1    Banos, J.G.2    Covarrubias, A.A.3    Garay-Arroyo, A.4
  • 9
    • 0033168682 scopus 로고    scopus 로고
    • Lovastatin biosynthesis in Aspergillus terrus: Characterization of blocked mutants, enzyme activities and a mulifunctional polyketide synthase gene
    • Hendrickson L, Davis CR, Roach C, Nguyen DK, Aldrich T, McAda PC, et al. Lovastatin biosynthesis in Aspergillus terrus: characterization of blocked mutants, enzyme activities and a mulifunctional polyketide synthase gene. Chem Biol 1999; 6: 429-439.
    • (1999) Chem Biol , vol.6 , pp. 429-439
    • Hendrickson, L.1    Davis, C.R.2    Roach, C.3    Nguyen, D.K.4    Aldrich, T.5    McAda, P.C.6
  • 10
    • 0033591447 scopus 로고    scopus 로고
    • Modulation of polyketides synthase activity by accessory proteins during lovastatin biosynthesis
    • Kennedy J, Auclair K, Kendrew SG, Park C, Vederas JC, Hutchinson CR. Modulation of polyketides synthase activity by accessory proteins during lovastatin biosynthesis. Science 1999; 284: 1368-1372.
    • (1999) Science , vol.284 , pp. 1368-1372
    • Kennedy, J.1    Auclair, K.2    Kendrew, S.G.3    Park, C.4    Vederas, J.C.5    Hutchinson, C.R.6
  • 12
    • 0031164761 scopus 로고    scopus 로고
    • Evolution of a fungal regulatory gene family: The Zn(II)2Cys6 binuclear cluster DNA binding motif
    • Todd RB, Andrianopoulos A. Evolution of a fungal regulatory gene family: the Zn(II)2Cys6 binuclear cluster DNA binding motif. Fungal Genet Biol 1997; 21: 388-405.
    • (1997) Fungal Genet Biol , vol.21 , pp. 388-405
    • Todd, R.B.1    Andrianopoulos, A.2
  • 13
    • 67649139174 scopus 로고    scopus 로고
    • Method of producing antihypercholesterolemic agents
    • US Patent 2004033570, 02-19
    • Park C, Hutchinson CR, Kennedy J. Method of producing antihypercholesterolemic agents. US Patent 2004033570, 2004-02-19.
    • (2004)
    • Park, C.1    Hutchinson, C.R.2    Kennedy, J.3
  • 15
    • 70349528936 scopus 로고    scopus 로고
    • Fungal Genetics Stock Center. [EB/OL], http://www.fgsc.net/fgn44/ weiland.html.
    • Fungal Genetics Stock Center. [EB/OL], http://www.fgsc.net/fgn44/ weiland.html.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.