Improving design and conduct of randomised trials by embedding them in qualitative research: ProtecT (prostate testing for cancer and treatment) study

British Medical Journal

Volumn 325, Issue 7367, 2002, Pages 766-769

  Donovan, Jenny ^a   Mills, Nicola ^a   Smith, Monica ^b   Brindle, Lucy ^a   Jacoby, Ann ^c   Peters, Tim ^a   Frankel, Stephen ^a   Neal, David ^b   Hamdy, Freddie ^d  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

^d UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROSTATE SPECIFIC ANTIGEN;

ADULT; AGED; CANCER RADIOTHERAPY; CANCER SCREENING; CANCER SURGERY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; HEALTH SERVICES RESEARCH; HUMAN; MAJOR CLINICAL STUDY; MALE; METHODOLOGY; PATIENT MONITORING; PRIORITY JOURNAL; PROSTATE CANCER; QUALITATIVE ANALYSIS; QUALITY CONTROL; RANDOMIZED CONTROLLED TRIAL; REVIEW;

EID: 0037027119     PISSN: 09598146     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (17)

1. Altman DG. Better reporting of randomised controlled trials: the CONSORT statement. BMJ 1996;313:570-1.
2. Lovato L, Hill K, Hertert S, Hunninghake D, Probstfield J. Recruitment for controlled clinical trials: literature summary and annotated bibliography. Control Clin Trials 1997;18:328-57.
3. Tognoni G, Alli C, Avanzini F, Bettelli G, Colombo F, Corso R, et al. Randomised clinical trials in general practice: lessons from a failure. BMJ 1991;303:969-71.
4. Pringle M, Churchill R. Randomised controlled trials in general practice: gold standard or fool's gold? BMJ 1995;311:1382-3.
5. Baum M. Reflections on randomised controlled trials in surgery. Lancet 1999;353:6-8.
6. Ross S, Grant A, Counsell C, Gillespie W, Russell I, Prescott R. Barriers to participation in randomised controlled trials: a systematic review. J Clin Epidemiol 1999;52:1143-56.
7. O'Reilly P, Martin L, Collins G. Few patients with prostate cancer are willing to be randomised to treatment [letter]. BMJ 1999;318:1556.
8. Livesey J, Cowan R, Brown C, Clarke N, Logue P, Lyons J, et al. Trial of randomisation between radical prostatectomy and radiotherapy in early prostate cancer. Clin Oncol 2000;12:63.
9. Glaser B, Strauss A. The discovery of grounded theory. Chicago: Aldine, 1967.
10. Ritchie J, Spencer L. Qualitative data analysis for applied policy research. In: Bryman A, Burgess R, eds. Analysing qualitative data. London: Routledge, 1994.
11. Selley S, Donovan JL, Faulkner A, Coast J, Gillatt D. Diagnosis, management and screening of early localised prostate cancer: a systematic review. Health Technol Asses 1997;1(2):1-96.
12. Featherstone K, Donovan J. Random allocation or allocation at random? Patients' perspectives of participation in a randomised controlled trial. BMJ 1999;317:1177-80.
13. Donovan JL, Blake D. "Just a touch of arthritis, doctor?" Qualitative study of interpretation of reassurance among patients attending rheumatology clinics. BMJ 2000;320:541-4.
14. Mays N, Pope C. Qualitative research in health care. London: BMJ, 1996.
15. Snowdon C, Garcia J, Elbourne D. Making sense of randomisation: responses of parents of critically ill babies to random allocation of treatment in a clinical trial. Soc Sci Med 1997;45:1337-55.
16. Roberson N. Clinical trial participation. Viewpoints from racial/ethnic groups. Cancer 1994;74:2687-91.
17. Featherstone K. Donovan JL. "Why don't they just tell me straight, why allocate it?" The struggle to make sense of participating in a randomised controlled trial. Soc Sci Med 2002;55:709-19.