Recruiting patients to medical research: Double blind randomised trial of "opt-in" versus "opt-out" strategies

British Medical Journal

Volumn 331, Issue 7522, 2005, Pages 940-942

  Junghans, Cornelia ^a   Feder, Gene ^b   Hemingway, Harry ^a   Timmis, Adam ^c   Jones, Melvyn ^b  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c BARTS HEALTH NHS TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ANGINA PECTORIS; ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; ETHICS; FEMALE; GENERAL PRACTICE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL RESEARCH; PRIORITY JOURNAL; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; RISK FACTOR; UNITED KINGDOM;

BIOMEDICAL AND BEHAVIORAL RESEARCH; EMPIRICAL APPROACH;

ADULT; AGED; ANGINA PECTORIS; DOUBLE-BLIND METHOD; ETHICS COMMITTEES, RESEARCH; FEMALE; HUMANS; INFORMED CONSENT; MALE; MIDDLE AGED; PATIENT COMPLIANCE; PATIENT SELECTION; PERSONAL AUTONOMY; PROGNOSIS; RESEARCH DESIGN; SELECTION BIAS;

EID: 27144455789     PISSN: 09598146     EISSN: None     Source Type: Journal    
DOI: 10.1136/bmj.38583.625613.AE     Document Type: Article

References (11)

1. Sommerville A. What's wrong with opting out? (Commentary). BMJ 2001;322:1220.
2. Young AF, Dobson AJ, Byles JE. Health services research using linked records: who consents and what is the gain? Aust N Z J Public Health 2001;25:417-20.
3. Woolf SH, Rothermich SF, Johnson RE, Marsland DW. Selection bias from requiring patients to give consent to examine data for health services research. Arch Fam Med 2000;9:1111-8.
4. Stanley B, Fraser J, Cox NH. Uptake of HIV screening in genito-urinary medicine after change to "opt out" consent. BMJ 2003;326:1174.
5. Rogers CG, Tyson JE, Kennedy KA, Broyles RS, Hickman JF. Conventional consent with opting in versus simplified consent with opting out: an exploratory trial for studies that do not increase patient risk. J Pediatr 1998;132:606-11.
6. Mutch L, King R. Obtaining parental consent-opting in or opting out? Arch Dis Child 1985;60:979-80.
7. Evans S, Day S, Royston P. MINIM: A programme for randomising patients to groups in clinical trials by the method of minimisation. Version 1.5. London Hospital Medical School.
8. Jones AM, Bamford B. The other face of research governance. BMJ 2004;329:280-1.
9. Ward HJT, Cousens SN, Smith-Bathgate B, Leitch M, Everington D, Will RG, et al. Obstacles to conducting epidemiological research in the UK general population. BMJ 2004;329:277-9.
10. Anderson LM, May DS. Has the use of cervical, breast, and colorectal cancer screening increased in the United States? Am J Public Health 1995;85:840-2.
11. Ebrahim S, Montaner D, Lawlor DA. Clustering of risk factors and social class in childhood and adulthood in British women's heart and health study: cross sectional analysis. BMJ 2004;328:861.