Differentiation of gram-negative bacterial aerosol exposure using detected markers in bronchial-alveolar lavage fluid

PLoS ONE

Volumn 4, Issue 9, 2009, Pages

  Wunschel, David ^a   Webb Robertson, Bobbie Jo ^a   Frevert, Charles W ^b   Skerrett, Shawn ^b   Beagley, Nat ^a   Willse, Alan ^a,c   Colburn, Heather ^a   Antolick, Kathryn ^a  

^a PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c MONSANTO COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CINNAMIC ACID; SINAPIC ACID;

AEROSOL; ANIMAL TISSUE; ARTICLE; COLONY FORMING UNIT; DISEASE MARKER; FRANCISELLA TULARENSIS; FRANCISELLA TULARENSIS NOVICIDA; GRAM NEGATIVE AEROBIC RODS AND COCCI; IMMUNE RESPONSE; LUNG LAVAGE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MICROBIAL ATTENUATION; MONONUCLEAR CELL; MOUSE; NONHUMAN; POLYMORPHONUCLEAR CELL; PSEUDOMONAS AERUGINOSA; ANIMAL; C57BL MOUSE; FEMALE; GRAM NEGATIVE BACTERIUM; LUNG; MALE; MASS SPECTROMETRY; METABOLISM; MICROBIOLOGY; PRINCIPAL COMPONENT ANALYSIS; VIRULENCE;

BACTERIA (MICROORGANISMS); FRANCISELLA TULARENSIS; MUS; NEGIBACTERIA; PSEUDOMONAS AERUGINOSA;

AEROSOLS; ANIMALS; BIOLOGICAL MARKERS; BRONCHOALVEOLAR LAVAGE FLUID; FEMALE; FRANCISELLA TULARENSIS; GRAM-NEGATIVE BACTERIA; LUNG; MALE; MICE; MICE, INBRED C57BL; PRINCIPAL COMPONENT ANALYSIS; PSEUDOMONAS AERUGINOSA; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; VIRULENCE;

EID: 70349515141     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007047     Document Type: Article

References (45)

1. Smoll J, Jackman J, Jett M, Moss O, White D, et al. (2003) Rapid determination of infection by mass spectrometry of breath. Experimental Lung Research 29: 108-109.
2. Kyriacou DN, Yarnold PR, Stein AC, Schmitt BP, Soltysik RC, et al. (2007) Discriminating inhalational anthrax from community-acquired pneumonia using chest radiograph findings and a clinical algorithm. Chest 131: 489-496.
3. Jackman J, Moss O (2004) Mass spectrometry of breath for the diagnosis of infection and exposure. Johns Hopkins Apl Technical Digest 25: 6-13.
4. Greenfield RA, Drevets DA, Machado LJ, Voskuhl GW, Bronze MS (2002) Bacterial pathogens as biological weapons and agents of bioterrorism. American Journal of the Medical Sciences 323: 299-315.
5. Friedlander AM, Welkos SL, Pitt MLM, Ezzell JW, Worsham PL, et al. (1993) Postexposure Prophylaxis Against Experimental Inhalation Anthrax. Journal of Infectious Diseases 167: 1239-1243.
6. Evans RG, Lawrence SJ (2006) Preparing for and responding to bioterrorist attacks - The role of disease management initiatives. Disease Management & Health Outcomes 14: 265-274.
7. Sasmano T, Hume D, eds (2004) The biology of Macrophages. Washington, DC: ASM Press.
8. Goodman RB, Strieter RM, Frevert CW, Cummings CJ, Tekamp-Olson P, et al. (1998) Quantitative comparison of C-X-C chemokines produced by endotoxin-stimulated human alveolar macrophages. American Journal of Physiology-Lung Cellular and Molecular Physiology 275: L87-L95.
9. Frevert CW, Kajikawa O, Wynant K, Martin TR (1998) CD14 and interleukin-8 are localized primarily to alveolar macrophages in a rabbit model of acute bacterial pneumonia. Faseb Journal 12: A788-A788.
10. Lee JS, Frevert CW, Matute-Bello G, Wurfel MM, Wong VA, et al. (2005) TLR-4 pathway mediates the inflammatory response but not bacterial elimination in E-coli pneumonia. American Journal of Physiology-Lung Cellular and Molecular Physiology 289: L731-L738.
11. Zhang H, Porro G, Orzech N, Mullen B, Liu MY, et al. (2001) Neutrophil defensins mediate acute inflammatory response and lung dysfunction in dose-related fashion. American Journal of Physiology-Lung Cellular and Molecular Physiology 280: L947-L954.
12. Visentainer JEL, Lieber SR, Persoli LBL, Vigorito AC, Aranha FJP, et al. (2003) Serum cytokine levels and acute graft-versus-host disease after HLA-identical hematopoietic stem cell transplantation. Experimental Hematology 31: 1044-1050.
13. Sack U, Scheibe R, Wotzel M, Hammerschmidt S, Kuhn H, et al. (2006) Multiplex analysis of cytokines in exhaled breath condensate. Cytometry Part A 69A: 169-172.
14. Robroeks C, Jobsis Q, Damoiseaux J, Heijmans PHM, Rosias PPR, et al. (2006) Cytokines in exhaled breath condensate of children with asthma and cystic fibrosis. Annals of Allergy Asthma & Immunology 96: 349-355.
15. Beineke A, Siebert U, van Elk N, Baumgartner W (2004) Development of a lymphocyte-transformation-assay for peripheral blood lymphocytes of the harbor porpoise and detection of cytokines using the reverse-transcription polymerase chain reaction. Veterinary Immunology and Immunopathology 98: 59-68.
16. Miyoshi S, Shinoda S (2000) Microbial metalloproteases and pathogenesis. Microbes and Infection 2: 91-98.
17. Lahteenmaki K, Kukkonen M, Korhonen TK (2001) The Pla surface protease/ adhesin of Yersinia pestis mediates bacterial invasion into human endothelial cells. Febs Letters 504: 69-72.
18. Lahteenmaki K, Kuusela P, Korhonen TK (2001) Bacterial plasminogen activators and receptors. Fems Microbiology Reviews 25: 531-552.
19. Van den Steen PE, Wuyts A, Husson SJ, Proost P, Van Damme J, et al. (2003) Gelatinase B/MMP-9 and neutrophil collagenase/MMP-8 process the chemokines human GCP-2/CXCL6, ENA-78/CXCL5 and mouse GCP-2/LIX and modulate their physiological activities. European Journal of Biochemistry 270: 3739-3749.
20. Van den Steen PE, Husson SJ, Proost P, Van Damme J, Opdenakker G (2003) Carboxyterminal cleavage of the chemokines MIG and IP-10 by gelatinase B and neutrophil collagenase. Biochemical and Biophysical Research Communications 310: 889-896.
21. Ayabe T, Satchell DP, Tanabe H, Hagen SJ, Wilson CL, et al. (2001) Processing and activation of alpha-defensins in mouse intestinal Paneth cells. Gastroenterology 120: A187-A187.
22. Senior BW, Woof JA (2005) Effect of mutations in the human immunoglobulin A1 (IgA1) hinge on its susceptibility to cleavage by diverse bacterial IgAl proteases. Infection and Immunity 73: 1515-1522.
23. Jin T, Bokarewa M, Foster T, Mitchell J, Higgins J, et al. (2004) Staphylococcus aureus resists human defensins by production of staphylokinase, a novel bacterial evasion mechanism. Journal of Immunology 172: 1169-1176.
24. Ardekani AM, Liotta LA, Petricoin EF (2002) Clinical potential of proteomics in the diagnosis of ovarian cancer. Expert Rev Mol Diagn 2: 312-320.
25. Kohn EC, Petricoin E, Liotta L (2002) SELDI-TOF/artificial intelligence (AI) heuristic algorithm analysis of serum to discriminate women with ovarian cancer from unaffected women. Proceedings of the American Association for Cancer Research Annual Meeting 43: 1163.
26. Lay JO (2001) MALDI-TOF mass spectrometry of bacteria. Mass Spectrometry Reviews 20: 172-194.
27. Holland RD, Duffy CR, Rafii F, Sutherland JB, Heinze TM, et al. (1999) Identification of bacterial proteins observed in MALDI TOF mass spectra from whole cells. Analytical Chemistry 71: 3226-3230.
28. Fenselau C, Demirev PA (2001) Characterization of intact microorganisms by MALDI mass spectrometry. Mass Spectrometry Reviews 20: 157-171.
29. Wunschel SC, Jarman KH, Petersen CE, Valentine NB, Wahl KL, et al. (2005) Bacterial analysis by MALDI-TOF mass spectrometry: An inter-lab oratory comparison. Journal of the American Society for Mass Spectrometry 16: 456-462.
30. Mellmann A, Cloud J, Maier T, Keckevoet U, Rarnminger I, et al. (2007) MALDI-TOF for species identification of nonfermenting bacteria: Evaluation and comparison to 16S rDNA sequencing. International Journal of Medical Microbiology 297: 16-17.
31. Mandrell R, Garbus B, Harden L (2007) Comparison of in-house and commercial software for analysis of MALDI-TOF-MS spectra of whole cell lysates for bacterial identification. Molecular & Cellular Proteomics 6: 58-58.
32. Pusch W (2007) Bruker Daltonics: leading the way from basic research to mass-spectrometry based clinical applications. Pharmacogenomics 8: 663-668.
33. Krader P, Emerson D (2004) Identification of archaea and some extremophilic bacteria using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry. Extremophiles 8: 259-268.
34. Issaq HJ, Conrads TP, Prieto DA, Tirumalai R, Veenstra TD (2003) SELDITOF MS for diagnostic proteomics. Analytical Chemistry 75: 148A-155A.
35. Prieto D, Conrads TP, Scudiero DA, Veenstra TD, Issaq HJ (2003) Profiling of secreted proteins from human ovarian cancer cell lines by surface-enhanced laser desorption ionization time-of-flight mass spectrometry. Journal of Liquid Chromatography & Related Technologies 26: 2315-2328.
36. Hajjar AM, Harvey MD, Shaffer SA, Goodlett DR, Sjostedt A, et al. (2006) Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors. Infection and Immunity 74: 6730-6738.
37. Lembo A, Pelletier M, Iyer R, Timko M, Dudda JC, et al. (2008) Administration of a synthetic TLR4 agonist protects mice from pneumonic tularemia. Journal of Immunology 180: 7574-7581.
38. Duenas AI, Aceves M, Orduna A, Diaz R, Crespo MS, et al. (2006) Francisella tularensis LPS induces the production of cytokines in human monocytes and signals via Toll-like receptor 4 with much lower potency than E. coli LPS. International Immunology 18: 785-795.
39. Hager AJ, Bolton DL, Pelletier MR, Brittnacher MJ, Gallagher LA, et al. (2006) Type IV pili-mediated secretion modulates Francisella virulence. Molecular Microbiology 62: 227-237.
40. Jarman KH, Cebula ST, Saenz AJ, Petersen CE, Valentine NB, et al. (2000) An algorithm for automated bacterial identification using matrix-assisted laser desorption/ionization mass spectrometry. Analytical Chemistry 72: 1217-1223.
41. Jarman KH, Daly DS, Petersen CE, Saenz AJ, Valentine NB, et al. (1999) Extracting and visualizing matrix-assisted laser desorption/ionization time-of-flight mass spectral fingerprints. Rapid Communications in Mass Spectrometry 13: 1586-1594.
42. Skerrett SJ, Wilson CB, Liggitt HD, Hajjar AM (2007) Redundant Toll-like receptor signaling in the pulmonary host response to Pseudomonas aeruginosa. American Journal of Physiology-Lung Cellular and Molecular Physiology 292: L312-L322.
43. West TE PM, Majure MC, Lembo A, Hajjar AM, Skerrett SJ (2008) Inhalation of Francisella novicida mglA causes replicative infection that elicits innate and adaptive responses but is not protective against invasive pneumonic tularemia. Microb Infect 10: 773-780.
44. Ott R, Longnecker M (2001) An Introduction to Statistical Methods and Data Analysis. Pacific Grove, CA.: Duxbury.
45. Devijver P, Kittler J (1982) Pattern Recognition: A statistical approach. London: Prentice-Hall.