Human telomerase reverse transcriptase (hTERT) Q169 is essential for telomerase function in vitro and in vivo

PLoS ONE

Volumn 4, Issue 9, 2009, Pages

  Wyatt, Haley D M ^a   Tsang, Allison R ^a   Lobb, Deirdre A ^a   Beattie, Tara L ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMINE; MUTANT PROTEIN; SINGLE STRANDED DNA; TELOMERASE REVERSE TRANSCRIPTASE; DNA; OLIGONUCLEOTIDE; RNA; TELOMERASE; TERT PROTEIN, HUMAN;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA TEMPLATE; ENZYME ACTIVITY; GENE INTERACTION; GENETIC CONSERVATION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; PROTEIN DEGRADATION; RESIDUE ANALYSIS; SITE DIRECTED MUTAGENESIS; CATALYSIS; CELL LINE; CHEMISTRY; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE;

EUKARYOTA;

CATALYSIS; CELL LINE; CELL LINE, TRANSFORMED; DNA; GLUTAMINE; HUMANS; MUTATION; OLIGONUCLEOTIDES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RNA; TELOMERASE;

EID: 70349490139     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007176     Document Type: Article

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