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Volumn 351, Issue 13, 2009, Pages 2075-2080

A symmetry-based synthesis of the heterobicyclic core of the zaragozic acids/squalestatins

Author keywords

Aldol reaction; Asymmetric catalysis; Chemoselectivity; Cyclization; Dihydroxylation; Two directional synthesis

Indexed keywords


EID: 70349433681     PISSN: 16154150     EISSN: 15213897     Source Type: Journal    
DOI: 10.1002/adsc.200900295     Document Type: Article
Times cited : (10)

References (47)
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    • 2, 0°C to room temperature, 80% 18), cf.
    • 2, 0°C to room temperature, 80% 18), cf.: J. R. Parikh, W. v. E. Doering, J. Am. Chem. Soc. 1967, 89, 5505-5507.
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    • The easily removable cyclopentylidene protecting groups were essential for an efficient intramolecular acetalization to give the desired heterobicyclic core. First experiments for this key step with the bis-isopropylidene protected analog of 22 snowed that one of the two isopropylidene protecting groups was not cleaved rapidly enough
    • The easily removable cyclopentylidene protecting groups were essential for an efficient intramolecular acetalization to give the desired heterobicyclic core. First experiments for this key step with the bis-isopropylidene protected analog of 22 snowed that one of the two isopropylidene protecting groups was not cleaved rapidly enough.
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    • CCDC 718839 contains the supplementary crystallography data for the structure 27 reported in this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via
    • CCDC 718839 contains the supplementary crystallography data for the structure 27 reported in this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data- request/cif.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.