Si-Ni-San, a traditional Chinese prescription, and its active ingredient glycyrrhizin ameliorate experimental colitis through regulating cytokine balance

International Immunopharmacology

Volumn 9, Issue 12, 2009, Pages 1437-1443

  Sun, Yang ^a   Cai, Tian Tian ^a   Shen, Yan ^a   Zhou, Xiao Bin ^a   Chen, Ting ^a   Xu, Qiang ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Crohn's disease; Glycyrrhizin; Inflammatory bowel disease; Si Ni San; TNBS

Indexed keywords

ACEBUTOLOL; CHINESE DRUG; GAMMA INTERFERON; GLYCYRRHIZIC ACID; INTERLEUKIN 10; INTERLEUKIN 12; MYELOPEROXIDASE; SI NI SAN; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; COLITIS; CONTROLLED STUDY; CROHN DISEASE; CYTOKINE PRODUCTION; DIARRHEA; DISEASE MODEL; DOSE RESPONSE; ENZYME ACTIVITY; FEMALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SURVIVAL;

ANIMALS; BODY WEIGHT; COLITIS; COLON; CROHN DISEASE; CYTOKINES; DIARRHEA; DISEASE MODELS, ANIMAL; DRUGS, CHINESE HERBAL; FEMALE; GLYCYRRHIZIC ACID; HUMANS; MEDICINE, CHINESE TRADITIONAL; MICE; MICE, INBRED C57BL; PEROXIDASE; TRINITROBENZENESULFONIC ACID;

EID: 70349433523     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2009.08.017     Document Type: Article

References (36)

1. Sospedra M., and Martin R. Immunology of multiple sclerosis. Annu Rev Immunol 23 (2005) 683-747
2. Toh M.L., and Miossec P. The role of T cells in rheumatoid arthritis: new subsets and new targets. Curr Opin Rheumatol 19 3 (2007) 284-288
3. Chan R.W.Y., Lai F.M.M., Li E.K.M., Tam L.S., Chow K.M., Li P.K.T., et al. Imbalance of Th1/Th2 transcription factors in patients with lupus nephritis. Rheumatology 45 (2006) 951-957
4. Strober W., Fuss I., and Mannon P. The fundamental basis of inflammatory bowel disease. J Clin Invest 117 3 (2007) 514-521
5. + lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-γ, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J Immunol 57 (1996) 1261-1270
6. Holtta V., Klemetti P., Sipponen T., Westerholm-Ormio M., Kociubinski G., Salo H., et al. IL-23/IL-17 immunity as a hallmark of Crohn's disease. Inflamm Bowel Dis 14 9 (2008) 1175-1184
7. Hanada T., and Yoshimura A. Regulation of cytokine signaling and inflammation. Cytokine Growth Factor Rev 13 4-5 (2002) 413-421
8. Neurath M.F., Finotto S., and Glimcher L.H. The role of Th1/Th2 polarization in mucosal immunity. Nat Med 8 6 (2002) 567-573
9. Correa I., Veny M., Esteller M., Piqué J.M., Yagüe J., Panés J., et al. Defective IL-10 production in severe phenotypes of Crohn's disease. J Leukoc Biol 85 (2009) 896-903
10. + regulatory T cells suppress Th1 mediated experimental colitis. Gut 55 (2006) 671-680
11. Rutgeerts P., Vermeire S., and Van Assche G. Biological therapies for inflammatory bowel diseases. Gastroenterology 136 4 (2009) 1182-1197
12. Thomas T., and Cohen R.D. Pharmacoeconomic considerations for inflammatory bowel disease in the era of biological therapies. Expert Rev Gastroenterol Hepatol 1 1 (2007) 101-112
13. Boyer D.L., Li B.U., Fyda J.N., and Friedman R.A. Sulfasalazine-induced hepatotoxicity in children with inflammatory bowel disease. J Pediatr Gastroenterol Nutr 8 4 (1989) 528-532
14. Vihinen M.K., Kolho K.L., Janne O.A., Andersson S., and Raivio T. Circulating adiponectin as a marker for glucocorticoid-related side effects in children and adolescents with inflammatory bowel disease. J Pediatr Gastroenterol Nutr 48 4 (2009) 504-506
15. Wang L., Zhou G.B., Liu P., Song J.H., Liang Y., Yan X.J., et al. Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia. PNAS 105 (2008) 4826-4831
16. Sun Y., Dong Y., Jiang H.J., Cai T.T., Chen L., Zhou X., et al. Dissection of the role of paeoniflorin in the traditional Chinese medicinal formula Si-Ni-San against contact dermatitis in mice. Life Sci 84 11-12 (2009) 337-344
17. Zhang Z.J., and Gu W.J. Treatise on febrile diseases. first ed (1996), China Press of Traditional Chinese Medicine, Beijing
18. Zhang F.W., and Zhang Y. Treatment of chronic atrophic gastritis by Si-Ni-San, fifty-eight cases. Chin J Tradi Chin Med Pharm 15 (2000) 79-80
19. Chen Z.S., Wei B.H., and Zhang W.D. Scheme on diagnosis and treatment of ulcerative colitis by integrative Chinese and Western medicine. Chin J Integr Tradit West Med 24 (2004) 1052-1055
20. Guo X.P., Li D.L., Li J.M., Liu Z.G., and Wang Y.M. Clinical pathological study of Si-Ni-San on treating chronic hepatitis and hepatic fibrosis. Chin J Inform Tradit Chin Med 6 (1999) 71-72
21. Yamamoto M., Kumagai A., and Yamamura Y. Structure and actions of saikosaponins isolated from Bupleurum falcatum L.I. Anti-inflammatory action of saikosaponins. Arzneimittelforschung 25 (1975) 1021-1023
22. Takagi K., and Harada M. Pharmacological studies on herb paeony root. I. Central effects of paeoniflorin and combined effects with licorice component Fm 100. Yakugaku Zasshi 89 (1969) 879-886
23. Rouseff R.L., Martin S.F., and Youtsey C.O. Quantitative survey of narirutin, naringin, hesperidin and neohesperidin in citrus. J Agric Food Chem 35 (1987) 1027-1030
24. Nikitina S.S. Some data on the mechanism of anti-inflammatory action of glycyrrhizic and glycyrrhetinic acids isolated from Glycirrhiza L. Farmakol Toksikol 29 (1966) 67-70
25. Yuan H., Ji W.S., Wu K.X., Jiao J.X., Sun L.H., and Feng Y.T. Anti-inflammatory effect of diammonium glycyrrhizinate in a rat model of ulcerative colitis. World J Gastroenterol 12 28 (2006) 4578-4581
26. Jiang J., Zhou C., and Xu Q. Alleviating effects of Si-Ni-San, a traditional Chinese prescription, on experimental liver injury and its mechanisms. Biol Pharm Bull 26 8 (2003) 1089-1094
27. Sun Y., Chen T., and Xu Q. Si-Ni-San, a traditional Chinese prescription, and its drug-pairs suppress contact sensitivity in mice via inhibiting activities of metalloproteinases and adhesion of T lymphocytes. J Pharm Pharmacol 55 6 (2003) 839-846
28. Zhang L., Dong Y., Sun Y., Chen T., and Xu Q. Role of four major components in the effect of Si-Ni-San, a traditional Chinese prescription, against contact sensitivity in mice. J Pharm Pharmacol 58 (2006) 1257-1264
29. Wirtz S., and Neurath M.F. Mouse models of inflammatory bowel disease. Adv Drug Deliv Rev 59 11 (2007) 1073-1083
30. Ruyssers N.E., De Winter B.Y., De Man J.G., Loukas A., Pearson M.S., Weinstock J.V., et al. Therapeutic potential of helminth soluble proteins in TNBS-induced colitis in mice. Inflamm Bowel Dis 15 4 (2009) 491-500
31. Foligne B., Nutten S., Steidler L., Dennin V., Goudercourt D., Mercenier A., et al. Recommendations for improved use of the murine TNBS-induced colitis model in evaluating anti-inflammatory properties of lactic acid bacteria: technical and microbiological aspects. Dig Dis Sci 51 2 (2006) 390-400
32. Hanauer S.B. Inflammatory bowel disease: epidemiology, pathogenesis, and therapeutic opportunities. Inflamm Bowel Dis 12 (2006) S3-S9
33. Shahrara S., Pickens S.R., Dorfleutner A., and Pope R.M. IL-17 induces monocyte migration in rheumatoid arthritis. J Immunol 182 (2009) 3884-3891
34. Song C., Luo L., Lei Z., Li B., Liang Z., Liu G., et al. IL-17-producing alveolar macrophages mediate allergic lung inflammation related to asthma. J Immunol 181 (2008) 6117-6124
35. Duchmann R., and Zeitz M. T regulatory cell suppression of colitis: the role of TGF-β. Gut 55 (2006) 604-606
36. Fuss I.J., Boirivant M., Lacy B., and Strober W. The interrelated roles of TGF-β and IL-10 in the regulation of experimental colitis. J Immunol 168 (2002) 900-908