Mast cells induce migration of dendritic cells in a murine model of acute allergic airway disease

International Archives of Allergy and Immunology

Volumn 151, Issue 3, 2010, Pages 214-222

  Reuter, Sebastian ^a   Dehzad, Nina ^a   Martin, Helen ^a   Heinz, Anke ^a   Castor, Timo ^a   Sudowe, Stephan ^a   Reske Kunz, Angelika B ^a   Stassen, Michael ^a   Buhl, Roland ^a   Taube, Christian ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Asthma; Dendritic cells; Inflammation; Mast cells; Murine model

Indexed keywords

FLUORESCENT DYE; OVALBUMIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL MIGRATION; CONTROLLED STUDY; DENDRITIC CELL; LUNG; LYMPH NODE; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT ALLERGY; SENSITIZATION;

ADOPTIVE TRANSFER; ALLERGENS; ANIMALS; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; CELL SEPARATION; CHEMOTAXIS, LEUKOCYTE; DENDRITIC CELLS; FLOW CYTOMETRY; MAST CELLS; MICE; OVALBUMIN;

EID: 70349412100     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000242359     Document Type: Article

References (29)

1. Taube C, Dakhama A, Gelfand EW: Insights into the pathogenesis of asthma utilizing murine models. Int Arch Allergy Immunol 2004; 135: 173-186.
2. Brightling CE, Bradding P, Symon FA, Holgate ST, Wardlaw AJ, Pavord ID: Mast-cell infiltration of airway smooth muscle in asthma. N Engl J Med 2002; 346: 1699-1705.
3. Williams CM, Galli SJ: Mast cells can amplify airway reactivity and features of chronic inflammation in an asthma model in mice. J Exp Med 2000; 192: 455-462.
4. Yu CK, Chen CL: Activation of mast cells is essential for development of house dust mite Dermatophagoides farinae -induced allergic airway inflammation in mice. J Immunol 2003; 171: 3808-3815.
5. Galli SJ, Nakae S, Tsai M: Mast cells in the development of adaptive immune responses. Nat Immunol 2005; 6: 135-142.
6. 1 histamine receptor regulates allergic lung responses. J Clin Invest 2006; 116: 1624-1632.
7. Nakae S, Ho LH, Yu M, Monteforte R, Iikura M, Suto H, Galli SJ: Mast cell-derived TNF contributes to airway hyperreactivity, inflammation, and Th2 cytokine production in an asthma model in mice. J Allergy Clin Immunol 2007; 120: 48-55.
8. Reuter S, Heinz A, Sieren M, Wiewrodt R, Gelfand EW, Stassen M, Buhl R, Taube C: Mast cell-derived tumour necrosis factor is essential for allergic airway disease. Eur Respir J 2008; 31: 773-782.
9. Hammad H, Lambrecht BN: Lung dendritic cell migration. Adv Immunol 2007; 93: 265-278.
10. Hammad H, Lambrecht BN: Dendritic cells and epithelial cells: linking innate and adaptive immunity in asthma. Nat Rev Immunol 2008; 8: 193-204.
11. van Rijt LS, Jung S, Kleinjan A, Vos N, Willart M, Duez C, Hoogsteden HC, Lambrecht BN: In vivo depletion of lung CD11c+ dendritic cells during allergen challenge abrogates the characteristic features of asthma. J Exp Med 2005; 201: 981-991.
12. Hammad H, Kool M, Soullié T, Narumiya S, Trottein F, Hoogsteden HC, Lambrecht BN: Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells. J Exp Med 2007; 204: 357-367.
13. Heib V, Becker M, Warger T, Rechtsteiner G, Tertilt C, Klein M, Bopp T, Taube C, Schild H, Schmitt E, et al: Mast cells are crucial for early inflammation, migration of Langerhans cells, and CTL responses following topical application of TLR7 ligand in mice. Blood 2007; 110: 946-953.
14. Suto H, Nakae S, Kakurai M, Sedgwick JD, Tsai M, Galli SJ: Mast cell-associated TNF promotes dendritic cell migration. J Immunol 2006; 176: 4102-4112.
15. Idzko M, Panther E, Corinti S, Morelli A, Ferrari D, Herouy Y, Dichmann S, Mockenhaupt M, Gebicke-Haerter P, Di Virgilio F, et al: Sphingosine 1-phosphate induces chemotaxis of immature and modulates cytokinerelease in mature human dendritic cells for emergence of Th2 immune responses. FASEB J 2002; 16: 625-627.
16. Bros M, Jährling F, Renzing A, Wiechmann N, Dang NA, Sutter A, Ross R, Knop J, Sudowe S, Reske-Kunz AB: A newly established murine immature dendritic cell line can be differentiated into a mature state, but exerts tolerogenic function upon maturation in the presence of glucocorticoid. Blood 2007; 109: 3820-3829.
17. Lambrecht BN, Pauwels RA, Fazekas De St Groth B: Induction of rapid T cell activation, division, and recirculation by intratracheal injection of dendritic cells in a TCR transgenic model. J Immunol 2000; 164: 2937-2946.
18. Bergstresser PR, Tigelaar RE, Tharp MD: Conjugated avidin identifies cutaneous rodent and human mast cells. J Invest Dermatol 1984; 83: 214-218.
19. Bussolati G, Gugliotta P: Nonspecific staining of mast cells by avidin-biotin-peroxidase complexes (ABC). J Histochem Cytochem 1983; 31: 1419-1421.
20. Bopp T, Dehzad N, Reuter S, Klein M, Ullrich N, Stassen M, Schild H, Buhl R, Schmitt E, Taube C: Inhibition of cAMP degradation improves regulatory T cell-mediated suppression. J Immunol 2009; 182: 4017-4024.
21. Yu M, Tsai M, Tam SY, Jones C, Zehnder J, Galli SJ: Mast cells can promote the development of multiple features of chronic asthma in mice. J Clin Invest 2006; 116: 1633-1641.
22. 4 receptor (BLT1) is required for effector CD8+ T cell-mediated, mast cell-dependent airway hyperresponsiveness. J Immunol 2006; 176: 3157-3164.
23. von Garnier C, Wikstrom ME, Zosky G, Turner DJ, Sly PD, Smith M, Thomas JA, Judd SR, Strickland DH, Holt PG, et al: Allergic airways disease develops after an increase in allergen capture and processing in the airway mucosa. J Immunol 2007; 179: 5748-5759.
24. Taube C, Wei X, Swasey CH, Joetham A, Zarini S, Lively T, Takeda K, Loader J, Miyahara N, Kodama T, et al: Mast cells, FcεRI, and IL-13 are required for development of airway hyperresponsiveness after aerosolized allergen exposure in the absence of adjuvant. J Immunol 2004; 172: 6398-6406.
25. Stumbles PA, Thomas JA, Pimm CL, Lee PT, Venaille TJ, Proksch S, Holt PG: Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th1 immunity. J Exp Med 1998; 188: 2019-2031.
26. Cumberbatch M, Dearman RJ, Antonopoulos C, Groves RW, Kimber I: Interleukin (IL)-18 induces Langerhans cell migration by a tumour necrosis factor-α- and IL-1β-dependent mechanism. Immunology 2001; 102: 323-330.
27. Lambrecht BN, De Veerman M, Coyle AJ, Gutierrez-Ramos JC, Thielemans K, Pauwels RA: Myeloid dendritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation. J Clin Invest 2000; 106: 551-559.
28. Krishnamoorthy N, Oriss TB, Paglia M, Fei M, Yarlagadda M, Vanhaesebroeck B, Ray A, Ray P: Activation of c-Kit in dendritic cells regulates T helper cell differentiation and allergic asthma. Nat Med 2008; 14: 565-573.
29. Zhou JS, Xing W, Friend DS, Austen KF, Katz HR: Mast cell deficiency in Kit(W-Sh) mice does not impair antibody-mediated arthritis. J Exp Med 2007; 204: 2797-2802.