Superoxides from mitochondrial complex III: The role of manganese superoxide dismutase

Free Radical Biology and Medicine

Volumn 29, Issue 2, 2000, Pages 170-180

  Raha, Sandeep ^a   McEachern, Gillian E ^a   Myint, A Tomoko ^a   Robinson, Brian H ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Complex III; Free radicals; Mitochondria; Reactive oxygen species

Indexed keywords

ANTIMYCIN A1; COPPER ZINC SUPEROXIDE DISMUTASE; FREE RADICAL; MANGANESE SUPEROXIDE DISMUTASE; MYXOTHIAZOL; STIGMATELLIN; SUPEROXIDE; UBIQUINOL CYTOCHROME C REDUCTASE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HEART MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SUBMITOCHONDRIAL PARTICLE;

ANIMALS; ANTIMYCIN A; ELECTRON TRANSPORT COMPLEX III; FREE RADICALS; ISOENZYMES; KINETICS; METHACRYLATES; MITOCHONDRIA, HEART; MODELS, CHEMICAL; POLYENES; RATS; RATS, WISTAR; SUBMITOCHONDRIAL PARTICLES; SUPEROXIDE DISMUTASE; SUPEROXIDES; THIAZOLES;

ANIMALIA;

EID: 0034661024     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(00)00338-5     Document Type: Article

References (36)

1. Dean R.T., Fu S., Stocker R., Davies M.J. Biochemistry and pathology of radical-mediated protein oxidation. Biochem. J. 324:1997;1-18.
2. Lenaz G. Role of mitochondria in oxidative stress and ageing. Biochim. Biophys. Acta. 1366:1998;53-67.
3. Boveris A. Mitochondrial production of superoxide radical and hydrogen peroxide. Adv. Exp. Med. Biol. 78:1977;67-82.
4. Ferrari R. The role of mitochondria in ischemic heart disease. J. Cardiovasc. Pharmacol. 28:(Suppl 1):1996;S1-S10.
5. Zhong Z., Arteel G.E., Connor H.D., Yin M., Frankenberg M.V., Stachlewitz R.F., Raleigh J.A., Mason R.P., Thurman R.G. Cyclosporin A increases hypoxia and free radical production in rat kidneys prevention by dietary glycine . Am. J. Physiol. 275:1998;F595-F604.
6. De Leo M.E., Borrello S., Passantino M., Palazzotti B., Mordente A., Daniele A., Filippini V., Galeotti T., Masullo C. Oxidative stress and overexpression of manganese superoxide dismutase in patients with Alzheimer's disease. Neurosci. Lett. 250:1998;173-176.
7. Rosen, D.; Siddique, T.; Patterson, D.; Figlewicz, D.; Sapp, P.; Hentati, A.; Donaldson, D.; Goto, J.; O'Regan, J.; Deng, H.; Rahman, Z.; Krizus, A.; Mckenna-Yasek, D.; Anarueber, C.; Gaston, S.; Berger, R.; Tanzi, R. Halperin, J.; Herzfeldt, B.; Van den Bergh, R.; Hung, W.; Bird, T.; Deng, G.; Mulder, D.; Smyth, C.; Laing, N.; Soriano, E.; Pericak-Vance, M.; Haines, J., Rouleau, G.; Gusella, J.; Horvitz, H.; Brown, R. Jr. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362:59-62; 1993.
8. Liu R., Althaus J., Ellerbrock B., Becker D., Gurney M. Enhanced oxygen radical production in a transgenic mouse model of familial amyotrophic lateral sclerosis. Ann. Neurol. 44:1998;763-770.
9. Pitkanen S., Robinson B.H. Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase. J. Clin. Invest. 98:1996;345-351.
10. Pitkanen S., Merante F., McLeod D.R., Applegarth D., Tong T., Robinson B.H. Familial cardiomyopathy with cataracts and lactic acidosis A defect in complex I (NADH-dehydrogense) of the mitochondria respiratory chain . Pediatr. Res. 39:1996;513-521.
11. Luo X., Pitkanen S., Kassovaska-Bratinova S., Robinson B.H., Lehotay D.C. Excessive formation of hydroxy radicals and aldehydic lipid peroxidation products in cultured skin fibroblasts from patients with complex I deficiency. J. Clin. Invest. 99:1997;2877-2882.
12. Robinson B.H. Human complex I deficiency clinical spectrum and involvement of oxygen free radicals in the pathogenicity of the defect . Biochem. Biophys. Acta. 1364:1998;271-286.
13. Bailey S.M., Pietsch E.C., Cunningham C.C. Ethanol stimulates the production of reactive oxygen species at mitochondrial complexes I and III [In Process Citation]. Free Radic. Biol. Med. 27:1999;891-900.
14. Trumpower B.L. The protonmotive Q cycle. Energy transduction by coupling of proton translocation to electron transfer by the cytochrome bc1 complex. J. Biol. Chem. 265:1990;11409-11412.
15. Matsuno-Yagi A., Hatefi Y. Ubiquinol-cytochrome c oxidoreductase. The redox reactions of the bis- heme cytochrome b in ubiquinone-sufficient and ubiquinone-deficient systems. J. Biol. Chem. 271:1996;6164-6171.
16. 1 complex Different domains of the quinol binding pocket and their role in the mechanism and binding of inhibitors . Biochemistry. 38:1999;15807-15826.
17. Del Maestro R., McDonald W. Subcellular localization of superoxide dismutases, glutathione peroxidase and catalase in developing rat cerebral cortex. Mech. Ageing Dev. 48:1989;15-31.
18. Craig E.E., Hood D.A. Influence of aging on protein import into cardiac mitochondria. Am. J. Physiol. 272:1997;H2983-H2988.
19. Pitkanen S., Raha S., Robinson B.H. Diagnosis of complex I deficiency in patients with lactic acidemia using skin fibroblast cultures. Biochem. Mol. Med. 59:1996;134-137.
20. Lowry O.H., Rosenbrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
21. Harmon H.J. Isolation of totally inverted submitochondrial particles by sonication of beef heart mitochondria. J. Bioenerg. Biomembr. 14:1982;377-386.
22. Hautecler J.J., Sluse-Goffart C.M., Evens A., Duyckaerts C., Sluse F.E. Effect of aspartate and glutamate on the oxoglutarate carrier investigated in rat heart mitochondria and inverted submitochondrial vesicles. Biochim. Biophys. Acta. 1185:1994;153-159.
23. Rees J.F., de Wergifosse B., Noiset O., Dubuisson M., Janssens B., Thompson E.M. The origins of marine bioluminescence turning oxygen defence mechanisms into deep-sea communication tools . J. Exp. Biol. 201:1998;1211-1221.
24. Lucas M., Solano F. Coelenterazine is a superoxide anion-sensitive chemiluminescent probe its usefulness in the assay of respiratory burst in neutrophils . Anal. Biochem. 206:1992;273-277.
25. 1 complex in Saccharomyces cervisiae. Submitted for publication to Biochem. Biophys. Acta; 2000.
26. (Gly) results in respiratory chain dysfunction. Hum. Mutat. 13:1999;245-254.
27. Ragan, C. I.; Wilson, M. T.; Darley-Usmar, V. M.; Lowe, P. N. Sub-fractionation of mitochondria and isolation of the proteins of oxidative phosphorylation. In: Darley-Usmar, V.; Rickwood, D.; Wilson, M. T., eds. Mitochondria: a practical approach. Washington, DC: IRL Press; 1987:79-112.
28. Tainer J.A., Getzoff E.D., Beem K.M., Richardson J.S., Richardson D.C. Determination and analysis of the 2 A-structure of copper, zinc superoxide dismutase. J. Mol. Biol. 160:1982;181-217.
29. Lang A.E., Lozano A.M. Parkinson's disease. First of two parts. N. Engl. J. Med. 339:1998;1044-1053.
30. Schapira A.H. Mitochondrial involvement in Parkinson's disease, Huntington's disease, hereditary spastic paraplegia and Friedreich's ataxia [see comments]. Biochim. Biophys. Acta. 1410:1999;159-170.
31. Turrens J.F., Alexandre A., Lehninger A.L. Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria. Arch. Biochem. Biophys. 237:1985;408-414.
32. Nohl H., Jordan W. The mitochondrial site of superoxide formation. Biochem. Biophys. Res. Commun. 138:1986;533-539.
33. Ishii N., Fujii M., Hartman P.S., Tsuda M., Yasuda K., Senoo-Matsuda N., Yanase S., Ayusawa D., Suzuki K. A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes [see comments]. Nature. 394:1998;694-697.
34. Ding H., Moser C.C., Robertson D.E., Tokito M.K., Daldal F., Dutton P.L. Ubiquinone pair in the Qo site central to the primary energy conversion reactions of cytochrome bc1 complex. Biochemistry. 34:1995;15979-15996.
35. Crofts A.R., Hong S., Ugulava N., Barquera B., Gennis R., Guergova-Kuras M., Berry E.A. Pathways for proton release during ubihydroquinone oxidation by the bc(1) complex. Proc. Natl. Acad. Sci. USA. 96:1999;10021-10026.
36. Matsuno-Yagi A., Hatefi Y. Ubiquinol-cytochrome c oxidoreductase. The redox reactions of the bis- heme cytochrome b in ubiquinone-sufficient and ubiquinone-deficient systems. J. Biol. Chem. 271:1996;6164-6171.