메뉴 건너뛰기




Volumn 238, Issue 10, 2009, Pages 2459-2470

The Pitx2c N-terminal domain is a critical interaction domain required for asymmetric morphogenesis

Author keywords

Chick embryo; Heart looping; Homeodomain; Left right patterning; Pitx2c

Indexed keywords

AMINO ACID; LEUCINE; PROCOLLAGEN; PROCOLLAGEN LYSYL HYDROXYLASE; TRANSCRIPTION FACTOR NKX2.5; TRANSCRIPTION FACTOR PITX2; TRANSCRIPTION FACTOR PITX2C; UNCLASSIFIED DRUG;

EID: 70349338915     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.22062     Document Type: Article
Times cited : (12)

References (57)
  • 3
    • 0032493822 scopus 로고    scopus 로고
    • The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities
    • Amendt BA, Sutherland LB, Semina EV, Russo AF. 1998. The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities. J Biol Chem 273:20066-20072.
    • (1998) J Biol Chem , vol.273 , pp. 20066-20072
    • Amendt, B.A.1    Sutherland, L.B.2    Semina, E.V.3    Russo, A.F.4
  • 4
    • 0032873653 scopus 로고    scopus 로고
    • Multifunctional role of the Pitx2 homeodomain protein C-terminal tail
    • Amendt BA, Sutherland LB, Russo AF. 1999. Multifunctional role of the Pitx2 homeodomain protein C-terminal tail. Mol Cell Biol 19:7001-7010.
    • (1999) Mol Cell Biol , vol.19 , pp. 7001-7010
    • Amendt, B.A.1    Sutherland, L.B.2    Russo, A.F.3
  • 6
    • 33646810876 scopus 로고    scopus 로고
    • Rotation of the myocardial wall of the outflow tract is implicated in the normal positioning of the great arteries
    • DOI 10.1161/01.RES.0000202800.85341.6e, PII 0000301220060217000019
    • Bajolle F, Zaffran S, Kelly RG, Hadchouel J, Bonnet D, Brown NA, Buckingham ME. 2006. Rotation of the myocardial wall of the outflow tract is implicated in the normal positioning of the great arteries. Circ Res 98:421-428. (Pubitemid 43755339)
    • (2006) Circulation Research , vol.98 , Issue.3 , pp. 421-428
    • Bajolle, F.1    Zaffran, S.2    Kelly, R.G.3    Hadchouel, J.4    Bonnet, D.5    Brown, N.A.6    Buckingham, M.E.7
  • 8
    • 0035101835 scopus 로고    scopus 로고
    • Improved method for chick whole-embryo culture using a filter paper carrier
    • DOI 10.1002/1097-0177(20010301)220:3<284::AID-DVDY1102>3.0.CO;2-5
    • Chapman SC, Collignon J, Schoenwolf GC, Lumsden A. 2001. Improved method for chick whole-embryo culture using a filter paper carrier. Dev Dyn 220:284-289. (Pubitemid 32173384)
    • (2001) Developmental Dynamics , vol.220 , Issue.3 , pp. 284-289
    • Chapman, S.C.1    Collignon, J.2    Schoenwolf, G.C.3    Lumsden, A.4
  • 10
    • 0141571141 scopus 로고    scopus 로고
    • Pitx2c attenuation results in cardiac defects and abnormalities of intestinal orientation in developing Xenopus laevis
    • Dagle JM, Sabel JL, Littig JL, Sutherland LB, Kolker SJ, Weeks DL. 2003. Pitx2c attenuation results in cardiac defects and abnormalities of intestinal orientation in developing Xenopus laevis. Dev Biol 262:268-281.
    • (2003) Dev Biol , vol.262 , pp. 268-281
    • Dagle, J.M.1    Sabel, J.L.2    Littig, J.L.3    Sutherland, L.B.4    Kolker, S.J.5    Weeks, D.L.6
  • 11
    • 46049120809 scopus 로고    scopus 로고
    • The Chirality of Gut Rotation Derives from Left-Right Asymmetric Changes in the Architecture of the Dorsal Mesentery
    • DOI 10.1016/j.devcel.2008.05.001, PII S1534580708001792
    • Davis NM, Kurpios NA, Sun X, Gros J, Martin JF, Tabin CJ. 2008. The chirality of gut rotation derives from left-right asymmetric changes in the architecture of the dorsal mesentery. Dev Cell 15:134-145. (Pubitemid 351895597)
    • (2008) Developmental Cell , vol.15 , Issue.1 , pp. 134-145
    • Davis, N.M.1    Kurpios, N.A.2    Sun, X.3    Gros, J.4    Martin, J.F.5    Tabin, C.J.6
  • 12
    • 0034023068 scopus 로고    scopus 로고
    • Mesendoderm and left-right brain, heart and gut development are differentially regulated by pitx2 isoforms
    • Essner JJ, Branford WW, Zhang J, Yost HJ. 2000. Mesendoderm and left-right brain, heart and gut development are differentially regulated by pitx2 isoforms. Development 127:1081-1093. (Pubitemid 30162654)
    • (2000) Development , vol.127 , Issue.5 , pp. 1081-1093
    • Essner, J.J.1    Branford, W.W.2    Zhang, J.3    Yost, H.J.4
  • 13
    • 0031043428 scopus 로고    scopus 로고
    • Pituitary homeobox 2, a novel member of the bicoidrelated family of homeobox genes, is a potential regulator of anterior structure formation
    • Gage PJ, Camper SA. 1997. Pituitary homeobox 2, a novel member of the bicoidrelated family of homeobox genes, is a potential regulator of anterior structure formation. Hum Mol Genet 6:457-464.
    • (1997) Hum Mol Genet , vol.6 , pp. 457-464
    • Gage, P.J.1    Camper, S.A.2
  • 14
    • 0032722672 scopus 로고    scopus 로고
    • Dosage requirement of Pitx2 for development of multiple organs
    • Gage PJ, Suh H, Camper SA. 1999. Dosage requirement of Pitx2 for development of multiple organs. Development 126:4643-4651.
    • (1999) Development , vol.126 , pp. 4643-4651
    • Gage, P.J.1    Suh, H.2    Camper, S.A.3
  • 15
    • 0038266156 scopus 로고    scopus 로고
    • PITX2 isoform-specific regulation of atrial natriuretic factor expression: Synergism and repression with Nkx2.5
    • DOI 10.1074/jbc.M210163200
    • Ganga M, Espinoza HM, Cox CJ, Morton L, Hjalt TA, Lee Y, Amendt BA. 2003. PITX2 isoform-specific regulation of atrial natriuretic factor expression: synergism and repression with Nkx2.5. J Biol Chem 278:22437-22445. (Pubitemid 36830296)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.25 , pp. 22437-22445
    • Ganga, M.1    Espinoza, H.M.2    Cox, C.J.3    Morton, L.4    Hjalt, T.A.5    Lee, Y.6    Amendt, B.A.7
  • 16
    • 38349000730 scopus 로고    scopus 로고
    • PITX2 controls asymmetric gonadal development in both sexes of the chick and can rescue the degeneration of the right ovary
    • Guioli S, Lovell-Badge R. 2007. PITX2 controls asymmetric gonadal development in both sexes of the chick and can rescue the degeneration of the right ovary. Development 134:4199-4208.
    • (2007) Development , vol.134 , pp. 4199-4208
    • Guioli, S.1    Lovell-Badge, R.2
  • 17
    • 44249106203 scopus 로고    scopus 로고
    • Breakthroughs and future challenges in left-right patterning
    • DOI 10.1111/j.1440-169X.2008.01008.x
    • Hamada H. 2008. Breakthroughs and future challenges in left-right patterning. Dev Growth Differ 50(suppl 1):S71-S78. (Pubitemid 351725076)
    • (2008) Development Growth and Differentiation , vol.50 , Issue.SUPPL. 1
    • Hamada, H.1
  • 18
    • 0027018236 scopus 로고
    • A series of normal stages in the development of the chick embryo. 1951
    • Hamburger V, Hamilton HL. 1992. A series of normal stages in the development of the chick embryo. 1951. Dev Dyn 195: 231-272.
    • (1992) Dev Dyn , vol.195 , pp. 231-272
    • Hamburger, V.1    Hamilton, H.L.2
  • 19
    • 31044445987 scopus 로고    scopus 로고
    • Current molecular understanding of Axenfeld-Rieger syndrome
    • Hjalt TA, Semina EV. 2005. Current molecular understanding of Axenfeld-Rieger syndrome. Expert Rev Mol Med 7:1-17.
    • (2005) Expert Rev Mol Med , vol.7 , pp. 1-17
    • Hjalt, T.A.1    Semina, E.V.2
  • 20
    • 0035809197 scopus 로고    scopus 로고
    • PITX2 regulates procollagen lysyl hydroxylase (PLOD) gene expression: Implications for the pathology of Rieger syndrome
    • Hjalt TA, Amendt BA, Murray JC. 2001. PITX2 regulates procollagen lysyl hydroxylase (PLOD) gene expression: implications for the pathology of Rieger syndrome. J Cell Biol 152:545-552.
    • (2001) J Cell Biol , vol.152 , pp. 545-552
    • Hjalt, T.A.1    Amendt, B.A.2    Murray, J.C.3
  • 21
    • 0023265819 scopus 로고
    • Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retroviral vectors
    • Hughes SH, Greenhouse JJ, Petropoulos CJ, Sutrave P. 1987. Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retroviral vectors. J Virol 61:3004-3012. (Pubitemid 17131484)
    • (1987) Journal of Virology , vol.61 , Issue.10 , pp. 3004-3012
    • Hughes, S.H.1    Greenhouse, J.J.2    Petropoulos, C.J.3    Sutrave, P.4
  • 22
    • 0031051863 scopus 로고    scopus 로고
    • Control of vertebrate left-right asymmetry by a snail-related zinc finger gene
    • DOI 10.1126/science.275.5304.1301
    • Isaac A, Sargent MG, Cooke J. 1997. Control of vertebrate left-right asymmetry by a Snail-related zinc finger gene. Science 275:1301-1304. (Pubitemid 27114157)
    • (1997) Science , vol.275 , Issue.5304 , pp. 1301-1304
    • Isaac, A.1    Sargent, M.G.2    Cooke, J.3
  • 25
    • 42549135492 scopus 로고    scopus 로고
    • Novel forms of Paired-like homeodomain transcription factor 2 (PITX2): Generation by alternative translation initiation and mRNA splicing
    • DOI 10.1186/1471-2199-9-31
    • Lamba P, Hjalt TA, Bernard DJ. 2008. Novel forms of Paired-like homeodomain transcription factor 2 (PITX2) generation by alternative translation initiation and mRNA splicing. BMC Mol Biol 9:31. (Pubitemid 351584223)
    • (2008) BMC Molecular Biology , vol.9 , pp. 31
    • Lamba, P.1    Hjalt, T.A.2    Bernard, D.J.3
  • 26
    • 0029939460 scopus 로고    scopus 로고
    • Ptx1, a bicoid-related homeo box transcription factor involved in transcription of the pro-opiomelanocortin gene
    • Lamonerie T, Tremblay JJ, Lanctot C, Therrien M, Gauthier Y, Drouin J. 1996. Ptx1, a bicoid-related homeobox transcription factor involved in transcription of the pro-opiomelanocortin gene. Genes Dev 10:1284-1295. (Pubitemid 26171108)
    • (1996) Genes and Development , vol.10 , Issue.10 , pp. 1284-1295
    • Lamonerie, T.1    Tremblay, J.J.2    Lanctot, C.3    Therrien, M.4    Gauthier, Y.5    Drouin, J.6
  • 27
    • 9944241753 scopus 로고    scopus 로고
    • Left-right asymmetry in embryonic development: A comprehensive review
    • DOI 10.1016/j.mod.2004.08.006, PII S0925477304002114
    • Levin M. 2005. Left-right asymmetry in embryonic development: a comprehensive review. Mech Dev 122:3-25. (Pubitemid 39593742)
    • (2005) Mechanisms of Development , vol.122 , Issue.1 , pp. 3-25
    • Levin, M.1
  • 28
    • 57349120584 scopus 로고    scopus 로고
    • A novel PITX2 mutation in a Chinese family with Axenfeld-Rieger syndrome
    • Li D, Zhu Q, Lin H, Zhou N, Qi Y. 2008. A novel PITX2 mutation in a Chinese family with Axenfeld-Rieger syndrome. Mol Vis 14:2205-2210.
    • (2008) Mol Vis , vol.14 , pp. 2205-2210
    • Li, D.1    Zhu, Q.2    Lin, H.3    Zhou, N.4    Qi, Y.5
  • 30
    • 0036066106 scopus 로고    scopus 로고
    • Directionality of heart looping: Effects of Pitx2c misexpression on flectin asymmetry and midline structures
    • DOI 10.1006/dbio.2002.0661
    • Linask KK, Yu X, Chen Y, Han M-D. 2002. Directionality of heart looping: effects of Pitx2c misexpression on flectin asymmetry and midline structures. Dev Biol 246: 407-417. (Pubitemid 34775356)
    • (2002) Developmental Biology , vol.246 , Issue.2 , pp. 407-417
    • Linask, K.K.1    Yu, X.2    Chen, Y.3    Han, M.-D.4
  • 31
    • 0037092595 scopus 로고    scopus 로고
    • Molecular genetics of Axenfeld-Rieger malformations
    • Lines MA, Kozlowski K, Walter MA. 2002. Molecular genetics of Axenfeld-Rieger malformations. Hum Mol Genet 11:1177-1184.
    • (2002) Hum Mol Genet , vol.11 , pp. 1177-1184
    • Lines, M.A.1    Kozlowski, K.2    Walter, M.A.3
  • 32
    • 0034954830 scopus 로고    scopus 로고
    • Regulation of left-right asymmetry by thresholds of Pitx2c activity
    • Liu C, Liu W, Lu MF, Brown NA, Martin JF. 2001. Regulation of left-right asymmetry by thresholds of Pitx2c activity. Development 128:2039-2048. (Pubitemid 32605652)
    • (2001) Development , vol.128 , Issue.11 , pp. 2039-2048
    • Liu, C.1    Liu, W.2    Lu, M.-F.3    Brown, N.A.4    Martin, J.F.5
  • 33
    • 0036849873 scopus 로고    scopus 로고
    • Pitx2c patterns anterior myocardium and aortic arch vessels and is required for local cell movement into atrioventricular cushions
    • Liu C, Liu W, Palie J, Lu MF, Brown NA, Martin JF. 2002. Pitx2c patterns anterior myocardium and aortic arch vessels and is required for local cell movement into atrioventricular cushions. Development 129:5081-5091. (Pubitemid 35355924)
    • (2002) Development , vol.129 , Issue.21 , pp. 5081-5091
    • Liu, C.1    Liu, W.2    Palie, J.3    Lu, M.F.4    Brown, N.A.5    Martin, J.F.6
  • 34
    • 0346888506 scopus 로고    scopus 로고
    • Genetic dissection of Pitx2 in craniofacial development uncovers new functions in branchial arch morphogenes, late aspects of tooth morphogenesis and cell migration
    • DOI 10.1242/dev.00849
    • Liu W, Selever J, Lu MF, Martin JF. 2003. Genetic dissection of Pitx2 in craniofacial development uncovers new functions in branchial arch morphogenesis, late aspects of tooth morphogenesis and cell migration. Development 130:6375-6385. (Pubitemid 38008834)
    • (2003) Development , vol.130 , Issue.25 , pp. 6375-6385
    • Liu, W.1    Selever, J.2    Lu, M.-F.3    Martin, J.F.4
  • 35
    • 0032493897 scopus 로고    scopus 로고
    • The transcription factor pitx2 mediates situs-specific morphogenesis in response to left-right asymmetric signals
    • DOI 10.1016/S0092-8674(00)81474-9
    • Logan M, Pagan-Westphal SM, Smith DM, Paganessi L, Tabin CJ. 1998. The transcription factor Pitx2 mediates situs-specific morphogenesis in response to left-right asymmetric signals. Cell 94:307-317. (Pubitemid 28376075)
    • (1998) Cell , vol.94 , Issue.3 , pp. 307-317
    • Logan, M.1    Pagan-Westphal, S.M.2    Smith, D.M.3    Paganessi, L.4    Tabin, C.J.5
  • 36
    • 0033575873 scopus 로고    scopus 로고
    • Function of Rieger syndrome gene in left-right asymmetry and craniofacial development
    • Lu MF, Pressman C, Dyer R, Johnson RL, Martin JF. 1999. Function of Rieger syndrome gene in left-right asymmetry and craniofacial development. Nature 401: 276-278. (Pubitemid 129515540)
    • (1999) Nature , vol.401 , Issue.6750 , pp. 276-278
    • Lu, M.-F.1    Pressman, C.2    Dyer, R.3    Johnson, R.L.4    Martin, J.F.5
  • 37
    • 0032493860 scopus 로고    scopus 로고
    • Pitx2 participates in the late phase of the pathway controlling left- Right asymmetry
    • DOI 10.1016/S0092-8674(00)81475-0
    • Piedra ME, Icardo JM, Albajar M, Rodriguez- Rey JC, Ros MA. 1998. Pitx2 participates in the late phase of the pathway controlling left-right asymmetry. Cell 94: 319-324. (Pubitemid 28376076)
    • (1998) Cell , vol.94 , Issue.3 , pp. 319-324
    • Piedra, M.E.1    Icardo, J.M.2    Albajar, M.3    Rodriguez-Rey, J.C.4    Ros, M.A.5
  • 38
    • 0036323255 scopus 로고    scopus 로고
    • Regulation of prolactin, GH, and Pit-1 gene expression in anterior pituitary by Pitx2: An approach using Pitx2 mutants
    • DOI 10.1210/en.143.8.2839
    • Quentien MH, Pitoia F, Gunz G, Guillet MP, Enjalbert A, Pellegrini I. 2002. Regulation of prolactin, GH, and Pit-1 gene expression in anterior pituitary by Pitx2: an approach using Pitx2 mutants. Endocrinology 143:2839-2851. (Pubitemid 34809854)
    • (2002) Endocrinology , vol.143 , Issue.8 , pp. 2839-2851
    • Quentien, M.-H.1    Pitoia, F.2    Gunz, G.3    Guillet, M.-P.4    Enjalbert, A.5    Pellegrini, I.6
  • 43
    • 0033991656 scopus 로고    scopus 로고
    • Pitx2 isoforms: Involvement of Pitx2c but not Pitx2a or Pitx2b in vertebrate left-right asymmetry
    • Schweickert A, Campione M, Steinbeisser H, Blum M. 2000. Pitx2 isoforms: involvement of Pitx2c but not Pitx2a or Pitx2b in vertebrate left-right asymmetry. Mech Dev 90:41-51.
    • (2000) Mech Dev , vol.90 , pp. 41-51
    • Schweickert, A.1    Campione, M.2    Steinbeisser, H.3    Blum, M.4
  • 45
    • 33646003223 scopus 로고    scopus 로고
    • Alterations in heart looping induced by overexpression of the tight junction protein Claudin-1 are dependent on its C-terminal cytoplasmic tail
    • Simard A, Di Pietro E, Young CR, Plaza S, Ryan AK. 2006. Alterations in heart looping induced by overexpression of the tight junction protein Claudin-1 are dependent on its C-terminal cytoplasmic tail. Mech Dev 123:210-227.
    • (2006) Mech Dev , vol.123 , pp. 210-227
    • Simard, A.1    Di Pietro, E.2    Young, C.R.3    Plaza, S.4    Ryan, A.K.5
  • 47
    • 0006889681 scopus 로고    scopus 로고
    • Cloning and expression pattern of chicken Pitx2: A new component in the SHH signaling pathway controlling embryonic heart looping
    • DOI 10.1006/bbrc.1998.8740
    • St Amand TR, Ra J, Zhang Y, Hu Y, Baber SI, Qiu M, Chen Y. 1998. Cloning and expression pattern of chicken Pitx2: a new component in the SHH signaling pathway controlling embryonic heart looping. Biochem Biophys Res Commun 247:100-105. (Pubitemid 28412533)
    • (1998) Biochemical and Biophysical Research Communications , vol.247 , Issue.1 , pp. 100-105
    • Amand, T.R.S.1    Ra, J.2    Zhang, Y.3    Hu, Y.4    Baber, S.I.5    Qiu, M.6    Chen, Y.7
  • 48
    • 0036339730 scopus 로고    scopus 로고
    • Pitx2 is required at multiple stages of pituitary organogenesis: Pituitary primordium formation and cell specification
    • Suh H, Gage PJ, Drouin J, Camper SA. 2002. Pitx2 is required at multiple stages of pituitary organogenesis: pituitary primordium formation and cell specification. Development 129:329-337. (Pubitemid 34863800)
    • (2002) Development , vol.129 , Issue.2 , pp. 329-337
    • Suh, H.1    Gage, P.J.2    Drouin, J.3    Camper, S.A.4
  • 49
    • 10644220151 scopus 로고    scopus 로고
    • Cell-specific activation of the atrial natriuretic factor promoter by PITX2 and MEF2A
    • DOI 10.1074/jbc.M404802200
    • Toro R, Saadi I, Kuburas A, Nemer M, Russo AF. 2004. Cell-specific activation of the atrial natriuretic factor promoter by PITX2 and MEF2A. J Biol Chem 279: 52087-52094. (Pubitemid 39656581)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.50 , pp. 52087-52094
    • Toro, R.1    Saadi, I.2    Kuburas, A.3    Nemer, M.4    Russo, A.F.5
  • 50
    • 0034101061 scopus 로고    scopus 로고
    • Transcriptional properties of Ptx1 and Ptx2 isoforms
    • Tremblay JJ, Goodyer CG, Drouin J. 2000a. Transcriptional properties of Ptx1 and Ptx2 isoforms. Neuroendocrinology 71:277-286. (Pubitemid 30312093)
    • (2000) Neuroendocrinology , vol.71 , Issue.5 , pp. 277-286
    • Tremblay, J.J.1    Goodyer, C.G.2    Drouin, J.3
  • 51
    • 0033854950 scopus 로고    scopus 로고
    • Formation of the definitive endoderm in mouse is a Smad2-dependent process
    • Tremblay KD, Hoodless PA, Bikoff EK, Robertson EJ. 2000b. Formation of the definitive endoderm in mouse is a Smad2-dependent process. Development 127:3079-3090.
    • (2000) Development , vol.127 , pp. 3079-3090
    • Tremblay, K.D.1    Hoodless, P.A.2    Bikoff, E.K.3    Robertson, E.J.4
  • 54
    • 4344659834 scopus 로고    scopus 로고
    • Novel identification of a four-base-pair deletion mutation in PITX2 in a Rieger syndrome family
    • Wang Y, Zhao H, Zhang X, Feng H. 2003. Novel identification of a four-base-pair deletion mutation in PITX2 in a Rieger syndrome family. J Dent Res 82:1008-1012. (Pubitemid 41713821)
    • (2003) Journal of Dental Research , vol.82 , Issue.12 , pp. 1008-1012
    • Wang, Y.1    Zhao, H.2    Zhang, X.3    Feng, H.4
  • 57
    • 0035073766 scopus 로고    scopus 로고
    • Differential expression and functional analysis of Pitx2 isoforms in regulation of heart looping in the chick
    • Yu X, St Amand TR, Wang S, Li G, Zhang Y, Hu YP, Nguyen L, Qiu MS, Chen YP. 2001. Differential expression and functional analysis of Pitx2 isoforms in regulation of heart looping in the chick. Development 128:1005-1013. (Pubitemid 32288209)
    • (2001) Development , vol.128 , Issue.6 , pp. 1005-1013
    • Yu, X.1    St Amand, T.R.2    Wang, S.3    Li, G.4    Zhang, Y.5    Hu, Y.6    Nguyen, L.7    Qiu, M.8    Chen, Y.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.